Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Determine how inhibition of autophagy/proteasome degradation or inhibition of protein synthesis in models of muscle insulin resistance affect amino acid metabolites (Study ST000511)

Reversed phase POSITIVE ION MODE (Analysis AN000784)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8
alpha-Amino-N-butyric-acid	ME157218	0.39	0.43	1.12	4.58	0.44	0.67	0.50	0.53
Anserine	ME157204	1.08	1.43	1.88	2.04	0.64	0.62	0.19	0.22
Carnosine	ME157203	1.24	1.58	1.26	1.45	0.88	0.85	0.34	0.33
gamma-Amino-N-butyric-acid	ME157212	0.30	0.52	0.22	0.29	1.13	1.04	2.23	2.14
Proline	ME157215	0.30	0.52	0.22	0.29	1.13	1.04	2.23	2.14
Phosphoethanolamine	ME157201	0.54	0.53	0.47	0.42	1.03	1.31	1.95	1.78
alpha-Aminoadipic-acid	ME157213	0.52	0.57	0.57	0.47	0.82	0.98	2.07	1.96
Glutamic Acid	ME157209	0.53	0.63	0.48	0.28	0.91	0.93	2.00	2.14
3-Methylhistidine^	ME157199	1.19	0.62	1.06	0.43	1.04	0.67	0.74	2.22
Cystathionine 1	ME157220	1.80	1.33	0.57	0.96	0.71	0.84	0.78	0.61
Aspartic Acid	ME157206	0.67	0.76	1.07	0.95	0.68	0.85	1.35	1.68
Ornithine	ME157219	0.69	0.97	0.44	0.64	1.01	0.93	1.65	1.56
Cystine	ME157223	0.61	0.72	0.53	0.76	1.18	1.55	1.36	1.42
Glycine	ME157237	0.69	0.95	0.39	0.63	1.17	1.48	1.32	1.37
Serine	ME157235	0.68	0.78	0.66	0.81	1.01	1.12	1.67	1.30
Asparagine	ME157200	0.61	0.73	0.73	0.84	1.21	1.32	1.41	1.27
Glutamine	ME157236	0.68	0.75	0.71	0.83	1.06	1.27	1.46	1.32
Arginine	ME157202	1.23	1.15	0.55	0.74	0.74	0.89	1.34	1.12
Hydroxyproline	ME157233	1.17	1.18	0.39	0.70	1.10	1.29	1.02	0.99
Histidine	ME157197	0.77	1.26	0.79	0.80	0.98	1.14	1.04	1.16
Tyrosine	ME157224	0.82	1.17	0.64	0.87	1.26	1.16	1.01	1.06
Ethanolamine	ME157205	0.83	0.99	1.03	1.17	1.14	1.14	0.85	0.96
Taurine	ME157234	1.06	1.11	0.99	1.10	0.92	1.00	0.84	0.97
Lysine	ME157222	1.14	0.96	0.87	1.17	0.70	0.77	1.14	1.14
Phenylalanine	ME157231	0.86	0.89	0.95	0.88	1.21	1.00	1.24	1.02
Citrulline	ME157208	1.05	1.02	0.79	0.94	1.05	1.09	1.11	0.91
Methionine	ME157225	0.93	0.98	0.77	0.91	1.15	1.04	1.18	1.04
Threonine	ME157211	0.79	0.75	0.93	1.18	0.87	0.93	1.42	1.19
Isoleucine	ME157227	0.87	0.74	0.94	1.09	0.94	1.00	1.37	1.11
Leucine	ME157230	0.84	0.72	0.99	1.07	0.95	0.97	1.43	1.11
Tryptophan	ME157232	0.89	0.82	0.87	1.02	1.03	0.98	1.21	1.22
Alanine	ME157238	0.93	0.91	0.78	1.13	0.97	1.09	1.08	1.13
Valine	ME157226	0.89	0.89	0.96	1.19	0.95	1.01	1.15	1.02
Hydroxylysine 2	ME157217	0.85	1.32	NA	NA	0.57	0.85	0.95	0.91
beta-alanine	ME157210	1.26	1.23	0.16	0.30	1.32	1.25	1.19	1.04
Sarcosine	ME157207	1.26	1.24	0.12	0.26	1.37	1.35	1.18	0.98

Factors:

F1	Group:Control \| Treatment:Colch
F2	Group:Control \| Treatment:Saline
F3	Group:HFD+Colch \| Treatment:Colch
F4	Group:HFD \| Treatment:Saline
F5	Group:IRKO \| Treatment:Colch
F6	Group:IRKO \| Treatment:Saline
F7	Group:MIGIRKO \| Treatment:Colch
F8	Group:MIGIRKO \| Treatment:Saline

Data matrix