Clustering data with hclust algorithm for Trace 13C-glucose, 13C-glutamine, and 13C-serine in genetically engineered pancreatic cell lines through free fatty acids (part I) (Study ST000642)
Reversed phase POSITIVE ION MODE (Analysis AN000974)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 13C-palmitate m0 | ME174845 | NA | NA | NA | NA | NA | 1.77 | 1.24 | 0.92 | 1.03 | 1.18 | 1.10 | 0.88 | 0.83 | 0.69 | 0.80 | 0.92 | 0.76 | 0.90 |
| 13C-stearate m0 | ME174885 | NA | NA | NA | NA | NA | 1.73 | 1.28 | 0.96 | 1.06 | 1.32 | 1.25 | 0.91 | 0.78 | 0.67 | 0.67 | 0.84 | 0.69 | 0.84 |
| 13C-myristate m0 | ME174828 | NA | NA | NA | NA | NA | 3.45 | 1.15 | 0.90 | 0.88 | 0.97 | 0.94 | 0.90 | 0.65 | 0.60 | 0.54 | 0.73 | 0.66 | 0.62 |
| 13C-oleate m0 | ME174865 | NA | NA | NA | NA | NA | 2.76 | 1.00 | 0.99 | 1.00 | 1.10 | 1.13 | 1.12 | 0.64 | 0.62 | 0.60 | 0.69 | 0.68 | 0.67 |
| 13C-palmitate m3 | ME174848 | NA | NA | NA | NA | NA | NA | 0.67 | 0.95 | 1.82 | NA | 1.86 | 0.57 | 0.26 | 1.70 | 0.82 | 0.06 | 1.57 | 0.71 |
| 13C-stearate m4 | ME174889 | NA | NA | NA | NA | NA | 0.00 | 1.05 | 1.54 | 1.33 | 1.18 | 1.44 | 2.50 | 0.23 | 0.38 | 0.38 | 0.53 | 1.30 | 1.13 |
| 13C-oleate m1 | ME174866 | NA | NA | NA | NA | NA | 0.00 | 1.37 | 1.01 | 1.02 | 1.16 | 1.03 | 1.34 | 0.55 | 1.11 | 0.93 | 0.94 | 2.18 | 0.35 |
| 13C-palmitate m4 | ME174849 | NA | NA | NA | NA | NA | 0.00 | 0.66 | 0.79 | 1.01 | 0.82 | 0.99 | 1.69 | 1.28 | 0.80 | 0.92 | 0.95 | 1.89 | 1.21 |
| 13C-palmitate m6 | ME174851 | NA | NA | NA | NA | NA | 0.00 | 0.64 | 0.79 | 0.96 | 0.63 | 1.01 | 1.63 | 1.17 | 0.96 | 1.09 | 0.91 | 1.80 | 1.42 |
| 13C-oleate m8 | ME174873 | NA | NA | NA | NA | NA | 0.00 | 0.55 | 0.62 | 0.79 | 0.87 | 1.02 | 1.23 | 1.39 | 0.98 | 1.01 | 0.84 | 1.87 | 1.84 |
| 13C-stearate m8 | ME174893 | NA | NA | NA | NA | NA | 0.00 | 0.62 | 0.52 | 0.77 | 0.50 | 0.86 | 1.62 | 1.25 | 1.05 | 1.05 | 0.96 | 2.11 | 1.69 |
| 13C-oleate m9 | ME174874 | NA | NA | NA | NA | NA | 0.00 | 1.47 | 1.19 | 0.87 | 0.75 | 0.90 | 1.33 | 1.45 | 0.46 | 1.36 | 0.97 | 1.03 | 1.22 |
| 13C-stearate m9 | ME174894 | NA | NA | NA | NA | NA | 0.00 | 1.16 | 0.84 | 0.92 | 1.46 | 0.74 | 1.28 | 1.25 | 1.25 | 1.25 | 0.32 | 1.22 | 1.31 |
| 13C-myristate m1 | ME174829 | NA | NA | NA | NA | NA | 0.00 | 0.59 | 1.11 | 1.22 | 1.04 | 1.07 | 1.00 | 1.01 | 1.30 | 1.21 | 1.08 | 1.21 | 1.15 |
| 13C-oleate m10 | ME174875 | NA | NA | NA | NA | NA | 0.00 | 0.97 | 0.93 | 1.04 | 0.91 | 0.87 | 1.15 | 1.19 | 0.98 | 1.22 | 1.09 | 1.29 | 1.36 |
| 13C-myristate m7 | ME174835 | NA | NA | NA | NA | NA | 0.00 | 0.96 | 0.98 | 1.05 | 1.10 | 0.94 | 0.96 | 1.12 | 1.20 | 1.23 | 1.14 | 1.16 | 1.17 |
| 13C-myristate m11 | ME174839 | NA | NA | NA | NA | NA | 0.00 | 0.97 | 1.06 | 1.02 | 1.05 | 1.04 | 1.00 | 1.11 | 1.19 | 1.20 | 1.11 | 1.11 | 1.14 |
| 13C-myristate m14 | ME174842 | NA | NA | NA | NA | NA | 0.00 | 0.92 | 1.04 | 1.04 | 1.01 | 1.00 | 1.00 | 1.15 | 1.20 | 1.21 | 1.13 | 1.14 | 1.15 |
| 13C-myristate m3 | ME174831 | NA | NA | NA | NA | NA | 0.00 | 0.94 | 1.05 | 1.05 | 1.00 | 0.99 | 0.99 | 1.15 | 1.22 | 1.21 | 1.14 | 1.13 | 1.14 |
| 13C-myristate m12 | ME174840 | NA | NA | NA | NA | NA | 0.00 | 0.98 | 1.08 | 1.08 | 1.02 | 1.01 | 1.05 | 1.13 | 1.13 | 1.18 | 1.11 | 1.08 | 1.16 |
| 13C-myristate m9 | ME174837 | NA | NA | NA | NA | NA | 0.00 | 0.99 | 1.02 | 1.05 | 1.04 | 0.96 | 1.02 | 1.16 | 1.14 | 1.22 | 1.12 | 1.10 | 1.18 |
| 13C-myristate m2 | ME174830 | NA | NA | NA | NA | NA | 0.00 | 0.86 | 0.97 | 1.03 | 1.05 | 1.07 | 1.06 | 1.17 | 1.14 | 1.17 | 1.11 | 1.21 | 1.17 |
| 13C-myristate m4 | ME174832 | NA | NA | NA | NA | NA | 0.00 | 0.81 | 0.98 | 1.05 | 1.06 | 1.08 | 1.06 | 1.15 | 1.15 | 1.17 | 1.10 | 1.22 | 1.17 |
| 13C-myristate m8 | ME174836 | NA | NA | NA | NA | NA | 0.00 | 0.95 | 0.97 | 1.03 | 1.00 | 1.08 | 1.11 | 1.14 | 1.11 | 1.13 | 1.10 | 1.18 | 1.18 |
| 13C-myristate m10 | ME174838 | NA | NA | NA | NA | NA | 0.00 | 0.96 | 1.06 | 1.04 | 1.00 | 1.04 | 1.12 | 1.16 | 1.12 | 1.16 | 1.06 | 1.16 | 1.13 |
| 13C-myristate m6 | ME174834 | NA | NA | NA | NA | NA | 0.00 | 0.96 | 1.06 | 1.04 | 1.00 | 1.04 | 1.12 | 1.16 | 1.12 | 1.16 | 1.06 | 1.16 | 1.13 |
| 13C-oleate m12 | ME174877 | NA | NA | NA | NA | NA | 0.00 | 0.98 | 0.95 | 1.01 | 0.81 | 0.85 | 0.99 | 1.28 | 1.15 | 1.32 | 1.18 | 1.28 | 1.20 |
| 13C-myristate m13 | ME174841 | NA | NA | NA | NA | NA | 0.00 | 0.91 | 0.96 | 1.02 | 0.94 | 1.01 | 0.91 | 1.17 | 1.26 | 1.25 | 1.21 | 1.16 | 1.19 |
| 13C-myristate m5 | ME174833 | NA | NA | NA | NA | NA | 0.00 | 0.91 | 1.01 | 1.01 | 0.96 | 0.96 | 0.96 | 1.18 | 1.23 | 1.23 | 1.19 | 1.17 | 1.19 |
| 13C-oleate m14 | ME174879 | NA | NA | NA | NA | NA | 0.00 | 1.03 | 1.00 | 0.96 | 0.90 | 0.90 | 0.97 | 1.24 | 1.17 | 1.29 | 1.14 | 1.19 | 1.21 |
| 13C-oleate m16 | ME174881 | NA | NA | NA | NA | NA | 0.00 | 1.04 | 1.01 | 1.00 | 0.92 | 0.87 | 0.87 | 1.23 | 1.24 | 1.25 | 1.19 | 1.17 | 1.22 |
| 13C-oleate m18 | ME174883 | NA | NA | NA | NA | NA | 0.00 | 0.97 | 0.97 | 0.94 | 0.92 | 0.89 | 0.88 | 1.24 | 1.30 | 1.26 | 1.22 | 1.19 | 1.22 |
| 13C-oleate m11 | ME174876 | NA | NA | NA | NA | NA | 0.00 | 1.17 | 0.98 | 0.78 | 0.83 | 0.87 | 0.90 | 1.43 | 1.19 | 1.25 | 1.30 | 1.07 | 1.23 |
| 13C-oleate m17 | ME174882 | NA | NA | NA | NA | NA | 0.00 | 0.97 | 0.92 | 0.90 | 0.76 | 0.76 | 0.77 | 1.37 | 1.45 | 1.19 | 1.35 | 1.27 | 1.29 |
| 13C-oleate m13 | ME174878 | NA | NA | NA | NA | NA | 0.00 | 0.93 | 0.93 | 1.01 | 0.83 | 0.80 | 0.91 | 1.35 | 1.39 | 1.29 | 1.23 | 1.15 | 1.20 |
| 13C-oleate m15 | ME174880 | NA | NA | NA | NA | NA | 0.00 | 0.99 | 1.02 | 1.01 | 0.85 | 0.73 | 0.81 | 1.26 | 1.32 | 1.31 | 1.30 | 1.24 | 1.16 |
| 13C-stearate m10 | ME174895 | NA | NA | NA | NA | NA | 0.00 | 0.59 | 0.84 | 1.02 | 0.59 | 0.70 | 1.33 | 1.25 | 1.32 | 1.32 | 1.02 | 1.62 | 1.41 |
| 13C-palmitate m7 | ME174852 | NA | NA | NA | NA | NA | NA | 0.63 | 0.90 | 0.84 | 0.78 | 0.83 | 1.30 | 1.00 | 1.07 | 1.07 | 1.02 | 1.39 | 1.17 |
| 13C-palmitate m8 | ME174853 | NA | NA | NA | NA | NA | 0.00 | 0.62 | 0.94 | 0.95 | 0.77 | 0.96 | 1.41 | 1.13 | 1.19 | 1.21 | 1.05 | 1.49 | 1.28 |
| 13C-stearate m17 | ME174902 | NA | NA | NA | NA | NA | 0.00 | 0.47 | 1.04 | 0.89 | 0.61 | 0.57 | 0.90 | 1.34 | 1.54 | 1.54 | 1.36 | 1.49 | 1.23 |
| 13C-stearate m18 | ME174903 | NA | NA | NA | NA | NA | 0.00 | 0.58 | 1.03 | 0.86 | 0.54 | 0.63 | 1.05 | 1.33 | 1.50 | 1.50 | 1.29 | 1.44 | 1.27 |
| 13C-stearate m13 | ME174898 | NA | NA | NA | NA | NA | 0.00 | 0.70 | 1.14 | 0.89 | 0.55 | 0.61 | 1.10 | 1.36 | 1.51 | 1.51 | 1.17 | 1.29 | 1.17 |
| 13C-stearate m14 | ME174899 | NA | NA | NA | NA | NA | 0.00 | 0.66 | 1.07 | 0.94 | 0.54 | 0.66 | 1.16 | 1.32 | 1.45 | 1.45 | 1.16 | 1.39 | 1.21 |
| 13C-stearate m15 | ME174900 | NA | NA | NA | NA | NA | 0.00 | 0.64 | 1.11 | 0.91 | 0.54 | 0.63 | 1.12 | 1.34 | 1.46 | 1.46 | 1.27 | 1.35 | 1.16 |
| 13C-stearate m16 | ME174901 | NA | NA | NA | NA | NA | 0.00 | 0.61 | 1.08 | 0.91 | 0.53 | 0.66 | 1.11 | 1.32 | 1.48 | 1.48 | 1.24 | 1.38 | 1.20 |
| 13C-stearate m11 | ME174896 | NA | NA | NA | NA | NA | 0.00 | 0.75 | 1.03 | 0.77 | 0.55 | 0.64 | 1.11 | 1.35 | 1.42 | 1.42 | 1.25 | 1.46 | 1.26 |
| 13C-stearate m12 | ME174897 | NA | NA | NA | NA | NA | 0.00 | 0.61 | 1.04 | 0.88 | 0.53 | 0.66 | 1.21 | 1.32 | 1.42 | 1.42 | 1.13 | 1.50 | 1.28 |
| 13C-palmitate m9 | ME174854 | NA | NA | NA | NA | NA | NA | 0.83 | 0.99 | 0.89 | 0.68 | 0.76 | 1.01 | 1.27 | 1.20 | 1.23 | 1.00 | 1.12 | 1.01 |
| 13C-palmitate m11 | ME174856 | NA | NA | NA | NA | NA | NA | 0.65 | 1.03 | 0.91 | 0.71 | 0.82 | 1.09 | 1.13 | 1.24 | 1.19 | 0.96 | 1.25 | 1.01 |
| 13C-palmitate m13 | ME174858 | NA | NA | NA | NA | NA | NA | 0.64 | 1.06 | 0.90 | 0.68 | 0.77 | 1.03 | 1.13 | 1.37 | 1.21 | 1.03 | 1.18 | 1.02 |
| 13C-palmitate m15 | ME174860 | NA | NA | NA | NA | NA | 0.00 | 0.62 | 1.03 | 0.86 | 0.74 | 0.82 | 1.01 | 1.25 | 1.55 | 1.30 | 1.21 | 1.41 | 1.21 |
| 13C-palmitate m18 | ME174863 | NA | NA | NA | NA | NA | 0.00 | 0.76 | 1.06 | 0.92 | 0.78 | 0.79 | 1.41 | 1.13 | 1.33 | 1.17 | 1.17 | 1.33 | 1.16 |
| 13C-palmitate m10 | ME174855 | NA | NA | NA | NA | NA | 0.00 | 0.82 | 1.04 | 0.96 | 0.75 | 0.86 | 1.18 | 1.32 | 1.27 | 1.30 | 1.07 | 1.28 | 1.14 |
| 13C-palmitate m16 | ME174861 | NA | NA | NA | NA | NA | 0.00 | 0.66 | 1.07 | 0.94 | 0.75 | 0.84 | 1.11 | 1.23 | 1.46 | 1.29 | 1.15 | 1.34 | 1.15 |
| 13C-palmitate m12 | ME174857 | NA | NA | NA | NA | NA | 0.00 | 0.72 | 1.14 | 1.01 | 0.77 | 0.90 | 1.20 | 1.23 | 1.34 | 1.23 | 1.06 | 1.29 | 1.11 |
| 13C-palmitate m14 | ME174859 | NA | NA | NA | NA | NA | 0.00 | 0.69 | 1.14 | 0.95 | 0.78 | 0.88 | 1.16 | 1.22 | 1.43 | 1.26 | 1.09 | 1.28 | 1.12 |
| 13C-oleate m2 | ME174867 | NA | NA | NA | NA | NA | 0.00 | 1.18 | 1.21 | 1.22 | 1.15 | 1.19 | 1.21 | 0.91 | 0.97 | 1.00 | 0.98 | 0.98 | 1.00 |
| 13C-oleate m4 | ME174869 | NA | NA | NA | NA | NA | 0.00 | 1.29 | 1.32 | 1.18 | 1.28 | 1.45 | 1.25 | 1.04 | 0.68 | 0.89 | 1.03 | 0.85 | 0.73 |
| 13C-stearate m2 | ME174887 | NA | NA | NA | NA | NA | 0.00 | 0.79 | 1.34 | 1.09 | 0.76 | 0.97 | 1.52 | 1.03 | 1.11 | 1.11 | 1.06 | 1.20 | 1.02 |
| 13C-palmitate m2 | ME174847 | NA | NA | NA | NA | NA | NA | 0.91 | 1.04 | 0.94 | 1.09 | 1.06 | 1.52 | 0.88 | 0.96 | 0.96 | 0.65 | 0.97 | 1.02 |
| 13C-palmitate m5 | ME174850 | NA | NA | NA | NA | NA | NA | 0.54 | 0.96 | 0.80 | 0.98 | 1.03 | 1.57 | 1.03 | 0.93 | 0.87 | 0.97 | 1.02 | 1.30 |
Factors:
| F1 | experiment:20_PSPH B7 + Dox (PKM1)_0 hr_No label | tracer:No Label | time:- |
| F2 | experiment:21_PSPH B7 + Dox (PKM1)_0 hr_No label | tracer:No Label | time:- |
| F3 | experiment:22_PSPH B7 + Dox (PKM1)_0 hr_No label | tracer:No Label | time:- |
| F4 | experiment:23_PSPH B7 - Dox (PKM2)_0 hr_No label | tracer:No Label | time:- |
| F5 | experiment:24_PSPH B7 - Dox (PKM2)_0 hr_No label | tracer:No Label | time:- |
| F6 | experiment:25_PSPH B7 - Dox (PKM2)_0 hr_No label | tracer:No Label | time:- |
| F7 | experiment:26_PSPH B7 + Dox (PKM1)_24 hr_13C-glucose | tracer:13C-glucose | time:24 |
| F8 | experiment:27_PSPH B7 + Dox (PKM1)_24 hr_13C-glucose | tracer:13C-glucose | time:24 |
| F9 | experiment:28_PSPH B7 + Dox (PKM1)_24 hr_13C-glucose | tracer:13C-glucose | time:24 |
| F10 | experiment:29_PSPH B7 - Dox (PKM2)_24 hr_13C-glucose | tracer:13C-glucose | time:24 |
| F11 | experiment:30_PSPH B7 - Dox (PKM2)_24 hr_13C-glucose | tracer:13C-glucose | time:24 |
| F12 | experiment:31_PSPH B7 - Dox (PKM2)_24 hr_13C-glucose | tracer:13C-glucose | time:24 |
| F13 | experiment:32_PSPH B7 + Dox (PKM1)_48 hr_13C-glucose | tracer:13C-glucose | time:48 |
| F14 | experiment:33_PSPH B7 + Dox (PKM1)_48 hr_13C-glucose | tracer:13C-glucose | time:48 |
| F15 | experiment:34_PSPH B7 + Dox (PKM1)_48 hr_13C-glucose | tracer:13C-glucose | time:48 |
| F16 | experiment:35_PSPH B7 - Dox (PKM2)_48 hr_13C-glucose | tracer:13C-glucose | time:48 |
| F17 | experiment:36_PSPH B7 - Dox (PKM2)_48 hr_13C-glucose | tracer:13C-glucose | time:48 |
| F18 | experiment:37_PSPH B7 - Dox (PKM2)_48 hr_13C-glucose | tracer:13C-glucose | time:48 |
