Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Slow Aging Mice Plasma Metabolomics (Study ST000705)

Reversed phase NEGATIVE ION MODE (Analysis AN001096)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16	F17
DEOXYCHOLIC ACID (2M-H)-	ME199357	2.01	0.61	0.86	1.78	0.63	0.48	0.66	2.36	1.04	8.79	0.37	NA	NA	1.38	0.72	0.22	0.10
GLYCOCHOLIC ACID (M-H)-	ME199367	0.06	0.02	0.28	0.15	1.23	0.08	0.16	0.10	3.70	0.06	0.05	0.12	NA	5.81	0.19	0.08	0.02
CHOLIC ACID (2M-H)-	ME199353	0.02	0.01	0.52	1.33	0.03	0.24	0.06	0.53	2.86	3.59	0.00	0.00	NA	3.05	0.69	0.03	0.00
GLUTATHIONE (OXIDIZED) (M-H)-	ME199365	0.14	0.16	0.68	1.12	1.18	0.53	0.72	0.36	2.41	1.32	0.64	1.04	NA	3.04	0.55	0.50	0.94
CHOLIC ACID (M+CL)-	ME199354	0.10	0.10	0.81	1.47	0.23	0.49	0.23	1.05	2.80	1.52	0.06	0.04	NA	4.47	1.41	0.15	0.06
CHOLIC ACID (M-H)-	ME199355	0.20	0.27	0.98	1.20	0.60	0.93	0.49	1.49	2.10	1.32	0.16	0.08	NA	3.36	1.93	0.39	0.17
XANTHURENIC ACID (M-H)-	ME199403	0.36	0.46	0.43	1.90	0.83	0.36	0.60	0.56	0.71	3.37	0.32	1.83	NA	1.74	0.65	0.52	0.41
MANDELIC ACID (M-H)-	ME199379	2.16	1.09	0.24	0.09	0.98	0.44	1.64	0.15	0.58	0.69	0.25	0.34	NA	1.07	1.91	0.38	NA
URSODIOL (M+HCOO)-	ME199401	0.43	0.41	1.40	0.89	0.28	1.10	0.46	1.92	0.91	1.83	0.11	0.11	NA	2.32	2.21	0.43	0.12
DEOXYURIDINE (M+HCOO)-	ME199358	0.21	NA	1.10	1.38	0.53	0.76	0.92	0.82	1.88	1.31	0.23	0.22	NA	1.27	1.59	0.57	0.54
THYMIDINE (M-H)-	ME199394	0.34	0.36	1.11	1.30	0.68	1.09	0.90	1.36	1.83	1.74	0.39	0.43	NA	1.50	1.59	0.46	0.74
BEHENIC ACID (M-H)-	ME199351	2.22	1.77	0.71	0.95	1.02	0.95	0.69	0.83	1.03	0.91	0.61	0.89	NA	1.21	0.55	0.66	0.86
OXALOACETIC ACID (M-H)-[-H2O]	ME199383	2.34	1.86	0.32	0.67	0.53	NA	0.75	1.80	1.35	1.94	0.54	0.39	NA	0.81	0.62	0.69	0.59
URSODIOL (M-H)-	ME199402	1.42	0.85	1.16	0.83	1.12	1.49	1.55	1.95	1.21	0.46	0.44	0.33	NA	0.59	0.79	1.03	0.46
ADIPIC ACID (M-H)-	ME199348	1.06	1.17	0.77	2.04	1.08	0.95	1.01	1.99	0.71	0.81	0.73	0.70	NA	0.97	0.59	0.85	0.83
GLUTARIC ACID (M-H)-	ME199364	1.86	1.41	1.20	1.73	0.64	1.67	0.55	1.72	0.36	0.54	1.03	0.66	NA	0.64	0.57	0.68	0.49
18:0 LYSO-PE (M-H)-	ME199344	0.49	0.51	1.12	0.18	1.22	1.24	0.83	0.70	1.63	0.71	1.07	0.79	NA	2.16	0.89	1.25	0.48
DUMP (M-H)-	ME199360	0.78	0.55	0.61	0.92	1.71	0.72	0.74	0.61	2.01	0.67	0.92	0.74	NA	1.78	0.96	0.96	0.80
BENZOIC ACID (M-H)-	ME199352	0.69	0.50	1.38	0.74	1.10	1.12	0.86	0.48	0.79	1.45	0.95	0.87	NA	0.86	2.27	1.19	0.72
CIS-ACONITIC ACID (M-H)-	ME199356	1.10	0.76	1.19	0.77	1.45	0.78	0.51	0.70	1.25	1.48	0.52	1.92	NA	1.08	0.89	1.05	0.68
ASPARTIC ACID (M-H)-	ME199350	1.02	1.19	0.97	0.65	1.54	1.15	1.54	0.83	1.05	0.66	0.73	0.80	NA	1.29	0.66	0.88	0.55
GLUTAMINE (M-H)-	ME199363	1.31	1.65	1.11	0.58	0.97	1.08	1.50	0.64	0.94	0.96	0.84	0.72	NA	0.96	0.74	1.21	0.47
N-ACETYL-L-PHENYLALANINE (M-H)-	ME199381	1.25	1.32	0.98	0.71	0.88	1.36	1.08	1.12	0.76	0.59	1.54	0.76	NA	0.90	0.93	0.99	0.53
PANTOTHENIC ACID (M+CL)-	ME199386	0.95	0.99	1.11	NA	0.98	1.24	0.84	0.38	1.01	0.38	1.31	0.46	NA	1.11	0.73	1.06	NA
PANTOTHENIC ACID (M-H)-	ME199387	1.06	1.16	0.75	0.39	1.21	1.28	0.95	0.55	1.33	0.70	1.71	0.53	NA	1.31	0.89	1.04	0.55
TRICARBALLYLIC ACID (M-H)-	ME199395	0.84	1.06	0.59	1.04	1.29	0.68	1.10	0.90	0.94	0.98	0.54	0.67	NA	0.85	1.08	1.76	1.80
HYODEOXYCHOLIC ACID (M-H)-	ME199370	1.02	1.08	0.81	1.19	0.96	1.00	1.09	0.47	0.98	1.66	0.45	1.00	NA	1.05	1.41	1.29	0.70
4-PYRIDOXIC ACID (M-H)-	ME199346	1.61	1.31	0.65	0.67	1.24	0.66	1.15	0.69	0.66	1.55	1.09	1.04	NA	1.02	1.26	0.84	0.68
KYNURENIC ACID (M-H)-	ME199372	1.31	1.57	0.67	1.07	0.90	0.79	1.08	0.87	0.50	1.66	0.86	1.35	NA	0.86	0.87	0.80	0.94
ISOCITRIC ACID (M-H)-	ME199371	0.97	1.01	0.71	1.20	0.87	0.90	1.32	1.29	0.81	0.87	1.04	0.76	NA	0.79	1.40	0.94	1.50
METHYL BETA-D-GALACTOSIDE (M+HCOO)-	ME199380	1.23	1.07	0.85	0.60	0.90	1.05	1.11	1.21	0.73	1.25	0.86	0.73	NA	0.78	1.73	0.70	1.23
5^-METHYLTHIOADENOSINE (M+CL)-	ME199347	0.56	0.72	0.97	1.40	0.63	1.02	0.99	1.31	1.18	1.30	0.80	1.03	NA	1.24	1.33	0.88	1.05
OXALIC ACID (M-H)-	ME199382	0.54	0.37	0.95	1.19	1.04	0.87	0.69	0.74	1.04	1.14	0.97	1.28	NA	1.25	1.42	1.05	1.47
S-ADENOSYL-L-HOMOCYSTEINE (M-H)-	ME199389	0.51	0.62	1.17	1.02	0.67	1.04	0.64	0.77	0.84	1.30	1.50	1.07	NA	1.15	1.47	0.78	0.95
URIC ACID (M-H)-	ME199399	0.93	0.73	0.87	1.17	1.10	1.11	0.89	0.90	0.90	0.62	0.97	0.74	NA	1.49	0.72	1.26	1.38
DOCOSAHEXAENOIC ACID (M-H)-	ME199359	0.72	0.85	1.08	0.85	1.36	0.98	0.97	0.98	1.55	0.76	0.82	0.81	NA	1.34	0.64	1.05	0.96
STEARIC ACID (M-H)-	ME199391	0.74	0.73	1.15	0.99	1.21	1.24	0.92	0.99	0.88	0.98	0.80	0.86	NA	1.80	0.70	0.90	0.88
PALMITOLEIC ACID (M-H)-	ME199385	0.52	0.63	1.19	0.91	1.52	1.25	1.01	0.88	1.08	1.49	0.55	1.05	NA	1.38	0.74	0.84	0.85
ELAIDIC ACID (M-H)-	ME199361	0.56	0.70	1.15	1.00	1.16	0.91	1.05	1.08	1.06	1.34	0.75	0.98	NA	1.45	0.87	0.98	0.95
PALMITIC ACID (M-H)-	ME199384	0.57	0.72	1.10	1.00	1.34	1.17	0.98	1.20	1.09	1.31	0.65	0.74	NA	1.31	0.88	0.93	0.97
HEPTADECANOIC ACID (M-H)-	ME199368	0.85	0.97	1.11	1.09	1.19	1.15	0.97	1.17	0.87	1.07	0.72	0.76	NA	1.36	0.76	0.95	0.96
LINOLEIC ACID (M-H)-	ME199377	0.75	0.93	1.21	0.91	1.43	1.19	1.08	1.24	1.02	1.17	0.57	0.85	NA	1.12	0.76	0.81	0.94
3-HYDROXY-3-METHYLGLUTARIC ACID (M-H)-	ME199345	0.74	1.02	0.92	1.06	1.06	1.18	0.92	1.26	0.81	1.42	0.72	0.77	NA	0.93	1.07	1.41	0.78
TRICARBALLYLIC ACID (M-H)-[-H2O]	ME199396	0.65	1.02	0.46	1.05	1.08	1.38	0.69	0.86	0.62	1.66	1.07	0.92	NA	0.96	1.03	1.20	1.12
SUCCINIC ACID (M-H)-	ME199392	1.43	1.15	0.77	0.94	1.15	0.79	1.11	0.80	0.68	0.87	1.03	0.94	NA	1.24	1.14	1.05	0.87
TAURINE (M-H)-	ME199393	1.16	1.40	0.73	1.07	1.02	0.97	1.04	1.10	0.89	1.04	0.94	0.98	NA	1.39	0.77	0.81	0.83
TRICOSANOIC ACID (M-H)-	ME199397	1.18	0.90	0.81	0.68	1.29	0.88	0.96	0.80	0.91	1.19	0.98	0.75	NA	1.06	0.83	1.44	1.14
LEUCINE (M-H)-	ME199376	0.95	0.74	0.93	0.93	0.72	1.05	0.69	0.77	1.06	0.93	1.19	0.93	NA	1.11	1.47	1.28	1.21
TRYPTOPHAN (2M-H)-	ME199398	0.88	0.99	0.92	0.66	0.83	0.97	0.97	0.76	1.03	0.85	1.45	0.75	NA	0.81	1.38	1.24	0.79
LYSINE (M-H)-	ME199378	0.96	0.67	1.23	0.87	0.94	1.31	0.69	1.04	1.10	0.73	1.35	0.83	NA	1.05	0.84	1.18	0.84
URIDINE (M-H)-	ME199400	0.76	0.66	1.11	1.25	0.88	1.13	0.75	1.10	1.14	0.93	1.02	0.95	NA	1.00	1.09	1.15	1.00
PHENYLALANINE (M-H)-	ME199388	1.00	1.01	1.00	0.93	0.71	1.08	0.93	1.04	1.14	0.95	1.12	1.00	NA	1.13	1.33	0.84	0.76
L-HISTIDINE (M-H)-	ME199373	1.04	1.20	0.88	0.84	0.88	1.00	1.24	0.94	1.02	0.92	1.22	1.12	NA	0.93	0.87	1.11	0.76
EPIBRASSINOLIDE [ISTD] (M+HCOO)-	ME199362	1.04	1.02	1.07	1.05	0.94	1.20	1.03	1.14	0.73	1.23	1.11	1.09	NA	0.60	0.84	1.05	0.96
L-[15N]ANTHRANILIC ACID [ISTD] (M-H)-	ME199375	0.97	0.97	1.26	1.15	0.89	1.19	0.86	1.14	0.90	0.93	1.05	0.97	NA	0.75	0.99	0.96	1.04
SEBACIC ACID (M-H)-	ME199390	0.99	1.09	0.92	1.12	1.32	0.97	1.01	0.89	1.10	1.06	0.86	0.79	NA	0.90	0.91	1.21	0.77
HEXACOSANOIC ACID (M-H)-	ME199369	1.06	1.11	0.90	0.84	1.20	0.85	0.99	0.92	0.98	1.02	0.99	0.89	NA	0.97	1.09	1.12	1.04
ALPHA-LINOLENIC ACID (M+HCOO)-	ME199349	0.86	0.96	1.02	1.02	1.11	1.06	1.04	1.10	0.98	1.22	0.79	0.87	NA	0.99	1.01	1.00	1.06
L-TRYPTOPHAN-15N2 [ISTD] (M-H)-	ME199374	0.92	0.97	1.12	0.98	0.99	1.10	0.97	1.03	0.99	0.96	1.01	0.87	NA	0.94	1.09	1.02	1.00
ZEATIN [ISTD] (M-H)-	ME199404	0.96	0.96	0.99	0.97	0.97	1.01	1.00	1.01	1.03	0.96	1.05	1.03	NA	0.96	1.01	1.03	1.05

Factors:

F1	Genotype:Dwarf \| Sex:F \| Strain:Snell
F2	Genotype:Dwarf \| Sex:M \| Strain:Snell
F3	Genotype:Het \| Sex:F \| Strain:PappA
F4	Genotype:Het \| Sex:M \| Strain:PappA
F5	Genotype:KO \| Sex:F \| Strain:GHRKO Global
F6	Genotype:KO \| Sex:F \| Strain:PappA
F7	Genotype:KO \| Sex:M \| Strain:GHRKO Global
F8	Genotype:KO \| Sex:M \| Strain:PappA
F9	Genotype:Neg \| Sex:F \| Strain:Liver GHRKO
F10	Genotype:Neg \| Sex:M \| Strain:Liver GHRKO
F11	Genotype:Normal \| Sex:F \| Strain:Snell
F12	Genotype:Normal \| Sex:M \| Strain:Snell
F13	Genotype:Pooled plasma \| Sex:Pooled plasma \| Strain:Pooled plasma
F14	Genotype:Pos \| Sex:F \| Strain:Liver GHRKO
F15	Genotype:Pos \| Sex:M \| Strain:Liver GHRKO
F16	Genotype:WT \| Sex:F \| Strain:GHRKO Global
F17	Genotype:WT \| Sex:M \| Strain:GHRKO Global

Data matrix