Clustering data with hclust algorithm for Absolute Quantification of 180 metabolites in serum from african american and european american in prostate cancer and case control samples (Study ST000783)
Direct infusion POSITIVE ION MODE (Analysis AN001239)| Metabolite | Structure | F1 | F2 | F3 | F4 |
|---|---|---|---|---|---|
| PEA | ME218417 | 1.32 | NA | 0.05 | NA |
| lysoPC a C26:1 | ME218270 | 0.57 | 1.73 | 0.26 | 1.40 |
| Putrescine | ME218418 | 0.49 | 2.00 | 0.77 | 0.66 |
| SM C22:3 | ME218360 | 0.45 | 1.87 | 0.73 | 1.14 |
| C18:1-OH | ME218385 | 1.20 | 0.85 | 0.25 | 1.65 |
| lysoPC a C24:0 | ME218268 | 1.51 | 0.66 | 0.08 | 1.73 |
| lysoPC a C26:0 | ME218269 | 1.39 | 0.64 | 0.05 | 1.92 |
| lysoPC a C28:0 | ME218271 | 1.27 | 0.70 | 0.10 | 1.94 |
| C16:1-OH | ME218378 | 1.00 | 0.89 | 0.22 | 1.88 |
| lysoPC a C28:1 | ME218272 | 0.96 | 0.75 | 0.39 | 1.95 |
| C14:1-OH | ME218374 | 0.75 | 0.79 | 0.28 | 2.20 |
| C14:2-OH | ME218376 | 0.79 | 0.85 | 0.30 | 2.08 |
| C16-OH | ME218380 | 0.79 | 0.98 | 0.24 | 1.99 |
| C5:1-DC | ME218398 | 0.78 | 0.93 | 0.39 | 1.91 |
| C14:2 | ME218375 | 1.11 | 0.90 | 0.52 | 1.45 |
| C9 | ME218404 | 1.08 | 1.01 | 0.42 | 1.45 |
| C14:1 | ME218373 | 0.88 | 0.85 | 0.63 | 1.66 |
| C7-DC | ME218402 | 0.84 | 0.86 | 0.63 | 1.68 |
| C5-OH (C3-DC-M) | ME218396 | 0.89 | 0.97 | 0.69 | 1.46 |
| C5-M-DC | ME218395 | 0.88 | 0.97 | 0.61 | 1.54 |
| C8 | ME218403 | 0.91 | 0.95 | 0.63 | 1.50 |
| C5-DC (C6-OH) | ME218400 | 0.84 | 0.99 | 0.50 | 1.68 |
| C16:2-OH | ME218382 | 0.83 | 1.01 | 0.53 | 1.62 |
| C5:1 | ME218397 | 0.86 | 1.03 | 0.49 | 1.61 |
| C16:1 | ME218379 | 0.91 | 0.92 | 0.51 | 1.67 |
| C4:1 | ME218393 | 0.96 | 0.94 | 0.51 | 1.58 |
| C3-OH | ME218389 | 0.91 | 1.03 | 0.33 | 1.71 |
| PC aa C24:0 | ME218273 | 0.92 | 1.08 | 0.41 | 1.59 |
| PC ae C42:4 | ME218343 | 1.04 | 0.93 | 0.37 | 1.63 |
| C16:2 | ME218381 | 0.89 | 0.89 | 0.42 | 1.80 |
| C14 | ME218372 | 0.92 | 0.95 | 0.36 | 1.76 |
| C3:1 | ME218390 | 0.96 | 0.88 | 0.37 | 1.78 |
| DOPA | ME218411 | 1.14 | 0.94 | 1.15 | 0.70 |
| PC ae C44:3 | ME218345 | 0.84 | 0.82 | 0.92 | 1.46 |
| PC aa C26:0 | ME218274 | 0.94 | 1.07 | 0.60 | 1.39 |
| PC ae C30:0 | ME218311 | 0.95 | 1.12 | 0.60 | 1.30 |
| PC ae C30:2 | ME218313 | 0.97 | 0.88 | 0.75 | 1.41 |
| C16 | ME218377 | 0.97 | 0.93 | 0.80 | 1.31 |
| C5 | ME218394 | 0.93 | 0.93 | 0.80 | 1.35 |
| PC aa C36:6 | ME218292 | 0.90 | 0.92 | 0.81 | 1.38 |
| C6:1 | ME218401 | 0.96 | 1.03 | 0.75 | 1.26 |
| lysoPC a C14:0 | ME218259 | 1.04 | 0.93 | 0.70 | 1.33 |
| PC ae C44:4 | ME218346 | 1.06 | 0.87 | 0.83 | 1.24 |
| C10:2 | ME218368 | 1.08 | 0.93 | 0.72 | 1.26 |
| C10 | ME218366 | 1.03 | 0.95 | 0.76 | 1.26 |
| C12 | ME218369 | 1.03 | 0.93 | 0.80 | 1.23 |
| C18 | ME218383 | 1.22 | 0.91 | 0.66 | 1.18 |
| lysoPC a C17:0 | ME218262 | 1.10 | 1.00 | 0.62 | 1.27 |
| Serotonin | ME218419 | 0.81 | 0.81 | 1.37 | 1.07 |
| PC ae C38:1 | ME218327 | 0.92 | 0.70 | 1.14 | 1.31 |
| PC ae C40:3 | ME218335 | 0.89 | 0.81 | 1.16 | 1.18 |
| Spermidine | ME218420 | 0.87 | 1.28 | 0.96 | 0.87 |
| Ac-Orn | ME218405 | 1.03 | 1.14 | 0.86 | 0.96 |
| Orn | ME218437 | 0.89 | 1.11 | 1.00 | 0.99 |
| PC aa C36:0 | ME218286 | 1.10 | 0.82 | 1.05 | 1.04 |
| PC ae C34:3 | ME218319 | 1.09 | 0.81 | 1.04 | 1.08 |
| PC aa C42:4 | ME218308 | 1.01 | 0.82 | 1.00 | 1.20 |
| PC aa C38:1 | ME218294 | 0.98 | 0.81 | 1.09 | 1.14 |
| PC aa C42:2 | ME218307 | 1.06 | 0.77 | 1.05 | 1.14 |
| cis-OH-Pro | ME218408 | 0.96 | 0.81 | 1.25 | 1.04 |
| Arg | ME218425 | 0.99 | 0.84 | 1.24 | 0.95 |
| Met-SO | ME218415 | 1.00 | 0.85 | 1.22 | 0.96 |
| Taurine | ME218423 | 0.87 | 0.91 | 1.20 | 1.06 |
| Ile | ME218433 | 0.95 | 0.88 | 1.15 | 1.05 |
| Met | ME218436 | 0.95 | 0.91 | 1.16 | 0.99 |
| PC aa C40:6 | ME218304 | 0.98 | 0.94 | 1.12 | 0.97 |
| PC aa C36:4 | ME218290 | 1.01 | 0.95 | 1.11 | 0.95 |
| SM C18:0 | ME218357 | 1.02 | 0.92 | 1.11 | 0.97 |
| SM C24:1 | ME218362 | 1.02 | 0.89 | 1.14 | 0.97 |
| PC aa C38:4 | ME218296 | 1.02 | 0.91 | 1.16 | 0.94 |
| SM C18:1 | ME218358 | 1.03 | 0.92 | 1.14 | 0.93 |
| PC aa C40:4 | ME218302 | 1.04 | 0.83 | 1.15 | 0.99 |
| PC ae C36:4 | ME218324 | 1.07 | 0.85 | 1.12 | 0.97 |
| PC ae C38:5 | ME218331 | 1.03 | 0.89 | 1.10 | 0.98 |
| PC ae C38:6 | ME218332 | 1.06 | 0.88 | 1.10 | 0.97 |
| SM C16:0 | ME218355 | 1.05 | 0.91 | 1.06 | 0.98 |
| SM C16:1 | ME218356 | 1.06 | 0.93 | 1.05 | 0.96 |
| PC ae C40:4 | ME218336 | 1.00 | 0.88 | 1.10 | 1.04 |
| PC ae C32:1 | ME218314 | 1.00 | 0.91 | 1.08 | 1.02 |
| PC aa C38:0 | ME218293 | 1.01 | 0.91 | 1.09 | 1.00 |
| PC ae C38:4 | ME218330 | 1.02 | 0.92 | 1.08 | 0.99 |
| ADMA | ME218406 | 0.92 | 1.03 | 1.06 | 1.00 |
| Cit | ME218428 | 0.95 | 1.02 | 1.05 | 0.99 |
| lysoPC a C20:4 | ME218267 | 0.99 | 1.01 | 1.08 | 0.92 |
| Creatinine | ME218410 | 0.95 | 1.00 | 1.10 | 0.96 |
| SM C20:2 | ME218359 | 0.96 | 0.98 | 1.13 | 0.93 |
| Tyr | ME218443 | 0.91 | 0.95 | 1.15 | 1.01 |
| Ala | ME218424 | 0.92 | 0.96 | 1.10 | 1.03 |
| Ser | ME218440 | 0.93 | 0.95 | 1.11 | 1.02 |
| Lys | ME218435 | 0.90 | 1.01 | 1.09 | 1.01 |
| Thr | ME218441 | 0.91 | 1.00 | 1.12 | 0.98 |
| Trp | ME218442 | 0.88 | 0.98 | 1.13 | 1.04 |
| Gly | ME218431 | 0.86 | 1.02 | 1.11 | 1.02 |
| Asn | ME218426 | 0.88 | 1.00 | 1.09 | 1.04 |
| Gln | ME218429 | 0.86 | 1.00 | 1.10 | 1.06 |
| PC aa C38:5 | ME218297 | 0.97 | 0.98 | 1.02 | 1.03 |
| PC ae C40:6 | ME218338 | 1.00 | 0.94 | 1.04 | 1.02 |
| PC aa C38:6 | ME218298 | 0.98 | 0.96 | 1.06 | 1.00 |
| PC aa C40:5 | ME218303 | 0.98 | 0.96 | 1.06 | 1.02 |
| Leu | ME218434 | 0.96 | 0.91 | 1.10 | 1.05 |
| PC ae C40:5 | ME218337 | 0.97 | 0.92 | 1.07 | 1.05 |
| Phe | ME218438 | 0.94 | 0.95 | 1.07 | 1.04 |
| Val | ME218444 | 0.94 | 0.94 | 1.08 | 1.06 |
| His | ME218432 | 0.92 | 0.96 | 1.05 | 1.08 |
| PC aa C38:3 | ME218295 | 0.94 | 0.94 | 1.06 | 1.08 |
| PC ae C44:5 | ME218347 | 0.83 | 1.04 | 0.99 | 1.15 |
| PC aa C32:1 | ME218279 | 0.85 | 0.99 | 0.97 | 1.21 |
| PC aa C42:0 | ME218305 | 0.86 | 1.02 | 0.97 | 1.17 |
| PC aa C42:5 | ME218309 | 0.86 | 1.02 | 0.93 | 1.18 |
| PC ae C30:1 | ME218312 | 0.92 | 1.09 | 0.79 | 1.19 |
| PC aa C40:1 | ME218299 | 0.90 | 1.03 | 0.90 | 1.16 |
| PC ae C34:0 | ME218316 | 0.93 | 1.06 | 0.86 | 1.14 |
| C4 | ME218391 | 0.89 | 1.09 | 0.86 | 1.16 |
| lysoPC a C16:1 | ME218261 | 0.90 | 1.07 | 0.89 | 1.14 |
| C10:1 | ME218367 | 1.02 | 0.97 | 0.83 | 1.17 |
| PC aa C28:1 | ME218275 | 1.04 | 0.98 | 0.80 | 1.18 |
| C12-DC | ME218370 | 1.04 | 1.00 | 0.84 | 1.10 |
| SM (OH) C14:1 | ME218350 | 1.03 | 0.97 | 0.88 | 1.11 |
| PC ae C38:2 | ME218328 | 0.98 | 0.88 | 0.97 | 1.19 |
| PC ae C38:3 | ME218329 | 0.92 | 0.89 | 1.00 | 1.22 |
| PC ae C42:3 | ME218342 | 0.95 | 0.89 | 0.96 | 1.23 |
| PC aa C40:2 | ME218300 | 0.91 | 0.88 | 1.05 | 1.19 |
| SM C26:1 | ME218364 | 0.93 | 0.92 | 1.00 | 1.16 |
| PC ae C36:2 | ME218322 | 0.96 | 0.96 | 0.91 | 1.17 |
| PC aa C30:0 | ME218276 | 0.98 | 0.94 | 0.92 | 1.16 |
| PC ae C36:1 | ME218321 | 0.98 | 0.94 | 0.90 | 1.18 |
| PC aa C36:5 | ME218291 | 0.95 | 1.00 | 0.89 | 1.17 |
| PC aa C32:2 | ME218280 | 0.93 | 0.98 | 0.93 | 1.17 |
| PC ae C42:0 | ME218339 | 0.93 | 0.96 | 0.92 | 1.20 |
| Glucose | ME218349 | 1.02 | 0.87 | 0.91 | 1.21 |
| PC ae C36:0 | ME218320 | 1.03 | 0.90 | 0.95 | 1.13 |
| C4-OH (C3-DC) | ME218392 | 1.01 | 0.91 | 0.93 | 1.17 |
| SM (OH) C16:1 | ME218351 | 1.00 | 0.92 | 0.94 | 1.15 |
| Asp | ME218427 | 1.09 | 0.93 | 0.90 | 1.08 |
| PC ae C32:2 | ME218315 | 1.05 | 0.92 | 0.94 | 1.09 |
| C12:1 | ME218371 | 1.07 | 0.88 | 1.01 | 1.04 |
| SM C24:0 | ME218361 | 1.05 | 0.91 | 1.02 | 1.03 |
| SM (OH) C22:2 | ME218353 | 1.05 | 0.93 | 1.01 | 1.01 |
| lysoPC a C18:0 | ME218263 | 1.05 | 0.96 | 0.96 | 1.03 |
| PC aa C30:2 | ME218277 | 1.04 | 0.93 | 0.99 | 1.05 |
| SM (OH) C22:1 | ME218352 | 1.02 | 0.93 | 0.99 | 1.06 |
| PC ae C34:2 | ME218318 | 1.05 | 0.89 | 0.99 | 1.09 |
| PC ae C36:3 | ME218323 | 1.02 | 0.88 | 1.01 | 1.11 |
| C3 | ME218388 | 0.98 | 0.93 | 0.97 | 1.12 |
| C2 | ME218387 | 0.96 | 0.92 | 1.03 | 1.11 |
| PC aa C40:3 | ME218301 | 0.97 | 0.91 | 1.04 | 1.11 |
| PC ae C40:1 | ME218333 | 1.01 | 0.91 | 1.02 | 1.08 |
| PC aa C34:4 | ME218285 | 1.00 | 0.90 | 1.01 | 1.10 |
| PC aa C36:2 | ME218288 | 0.99 | 0.92 | 1.01 | 1.09 |
| PC aa C36:1 | ME218287 | 0.97 | 0.94 | 1.01 | 1.09 |
| PC aa C32:0 | ME218278 | 0.98 | 0.96 | 1.00 | 1.07 |
| PC aa C34:2 | ME218283 | 1.00 | 0.94 | 0.99 | 1.08 |
| lysoPC a C20:3 | ME218266 | 1.01 | 1.06 | 0.89 | 1.03 |
| lysoPC a C18:2 | ME218265 | 1.00 | 1.00 | 0.95 | 1.05 |
| PC aa C42:1 | ME218306 | 1.01 | 0.99 | 0.92 | 1.06 |
| lysoPC a C18:1 | ME218264 | 0.96 | 1.04 | 0.97 | 1.03 |
| lysoPC a C16:0 | ME218260 | 1.00 | 1.01 | 0.98 | 1.01 |
| PC aa C32:3 | ME218281 | 0.98 | 1.02 | 0.99 | 1.01 |
| SDMA | ME218407 | 0.89 | 0.95 | 1.07 | 1.11 |
| PC ae C42:5 | ME218344 | 0.91 | 0.99 | 1.03 | 1.09 |
| PC ae C44:6 | ME218348 | 0.87 | 1.00 | 1.03 | 1.13 |
| PC ae C42:2 | ME218341 | 0.91 | 1.04 | 0.95 | 1.11 |
| Pro | ME218439 | 0.89 | 1.03 | 1.00 | 1.07 |
| C6 (C4:1-DC) | ME218399 | 0.98 | 0.99 | 0.92 | 1.11 |
| PC ae C34:1 | ME218317 | 0.96 | 0.98 | 0.95 | 1.12 |
| PC ae C38:0 | ME218326 | 0.94 | 0.99 | 0.95 | 1.13 |
| SM (OH) C24:1 | ME218354 | 0.95 | 1.00 | 0.94 | 1.12 |
| PC aa C34:3 | ME218284 | 0.91 | 0.98 | 0.98 | 1.14 |
| C0 | ME218365 | 0.96 | 1.00 | 0.98 | 1.07 |
| PC ae C42:1 | ME218340 | 0.95 | 0.96 | 1.01 | 1.10 |
| Kynurenine | ME218414 | 0.95 | 0.98 | 1.00 | 1.09 |
| PC aa C36:3 | ME218289 | 0.95 | 0.97 | 1.01 | 1.09 |
| PC aa C34:1 | ME218282 | 0.95 | 0.96 | 0.99 | 1.11 |
| PC ae C40:2 | ME218334 | 0.94 | 0.95 | 1.00 | 1.12 |
| C18:1 | ME218384 | 1.19 | 1.00 | 0.82 | 0.96 |
| PC aa C42:6 | ME218310 | 1.14 | 0.97 | 0.85 | 1.02 |
| Histamine | ME218413 | 1.19 | 0.89 | 0.94 | 0.96 |
| Carnosine | ME218409 | 1.14 | 1.00 | 0.97 | 0.92 |
| Spermine | ME218421 | 1.15 | 0.97 | 0.96 | 0.90 |
| Dopamine | ME218412 | 1.27 | 0.81 | 1.01 | 0.91 |
| Glu | ME218430 | 1.20 | 0.84 | 1.04 | 0.92 |
| PC ae C36:5 | ME218325 | 1.13 | 0.82 | 1.14 | 0.93 |
| trans-OH-Pro | ME218422 | 1.12 | 0.76 | 1.21 | 0.92 |
| Nitro-Tyr1) | ME218416 | 1.40 | 0.29 | 1.03 | 0.76 |
| C18:2 | ME218386 | 1.40 | 0.80 | 0.59 | 1.15 |
| SM C26:0 | ME218363 | 1.55 | 0.65 | 0.83 | 0.94 |
Factors:
| F1 | Status:Case control | RACE:AA |
| F2 | Status:Case control | RACE:EA |
| F3 | Status:Prostate cancer | RACE:AA |
| F4 | Status:Prostate cancer | RACE:EA |
