Clustering data with hclust algorithm for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 2:Liver (Study ST000915)
Core G Fatty acids/Eicosanoids (Analysis AN001485)Metabolite | Structure | F1 | F2 | F3 | F4 |
---|---|---|---|---|---|
5-iso PGF2a VI | ME230922 | 0.10 | 2.13 | 0.88 | 3.87 |
FA(26:0) | ME230997 | 0.20 | 0.17 | 2.47 | 0.21 |
LTE4 | ME230928 | 2.70 | 0.22 | 0.24 | 0.15 |
15-HETrE | ME230935 | 2.29 | 0.65 | 0.51 | 0.71 |
dhk PGF2a | ME230910 | 2.43 | 0.76 | 0.75 | 0.54 |
6k PGE1 | ME230906 | 2.20 | 0.20 | 0.97 | 0.51 |
6k PGF1a | ME230901 | 1.72 | 0.77 | 0.74 | 0.79 |
6,15 dk-,dh- PGF1a | ME230907 | 1.87 | 0.43 | 0.78 | 0.36 |
FA(20:3 N3) | ME230981 | 1.81 | 0.55 | 1.04 | 0.40 |
FA(22:2) | ME230988 | 1.69 | 0.62 | 0.92 | 0.55 |
15k PGF2a | ME230908 | 1.05 | 0.42 | 1.25 | 1.73 |
11-HEPE | ME230917 | 1.39 | 0.45 | 0.89 | 1.29 |
FA(22:3) | ME230989 | 1.97 | 0.35 | 0.99 | 1.38 |
9-oxoODE | ME230946 | 0.81 | 0.81 | 0.90 | 1.62 |
9,10 diHOME | ME230963 | 0.99 | 0.93 | 0.89 | 1.29 |
FA(15:0) | ME230967 | 1.02 | 0.80 | 0.99 | 1.32 |
FA(20:0) | ME230978 | 0.89 | 0.76 | 1.05 | 1.37 |
12-HETE | ME230938 | 0.48 | 0.96 | 1.11 | 1.50 |
14 HDoHE | ME230940 | 0.46 | 0.85 | 1.15 | 1.39 |
13-HODE | ME230934 | 0.80 | 1.09 | 0.89 | 1.32 |
9-HODE | ME230942 | 0.76 | 1.10 | 0.88 | 1.37 |
16 HDoHE | ME230926 | 0.59 | 1.10 | 0.99 | 1.31 |
9-HOTrE | ME230931 | 0.56 | 1.17 | 1.04 | 1.38 |
12-HEPE | ME230939 | 0.38 | 0.73 | 1.49 | 1.15 |
14,15-EET | ME230955 | 0.54 | 0.68 | 1.47 | 1.04 |
19,20 DiHDPA | ME230956 | 0.63 | 0.78 | 1.26 | 1.26 |
20-HETE | ME230947 | 0.80 | 0.90 | 1.10 | 1.23 |
5-oxoETE | ME230944 | 0.80 | 0.79 | 1.12 | 1.24 |
15-HEPE | ME230933 | 0.82 | 1.08 | 1.02 | 1.12 |
15-HETE | ME230932 | 0.89 | 1.01 | 1.01 | 1.10 |
12,13 diHOME | ME230964 | 1.01 | 1.00 | 0.95 | 1.08 |
FA(18:1) | ME230973 | 1.00 | 0.94 | 1.02 | 1.03 |
20 HDoHE | ME230927 | 0.64 | 1.09 | 1.09 | 1.09 |
PGF1a | ME230905 | 0.73 | 1.09 | 1.06 | 1.09 |
9,10 EpOME | ME230957 | 0.72 | 0.90 | 1.16 | 1.15 |
18-HETE | ME230949 | 0.76 | 0.87 | 1.22 | 1.01 |
5-HETE | ME230929 | 0.69 | 0.92 | 1.24 | 1.03 |
PGA2 | ME230919 | 0.82 | 0.99 | 1.12 | 1.07 |
9-HEPE | ME230925 | 0.74 | 0.94 | 1.16 | 1.02 |
12,13 EpOME | ME230958 | 0.81 | 0.89 | 1.16 | 1.05 |
PGE2 | ME230903 | 0.77 | 0.92 | 1.16 | 1.07 |
8-iso PGF2a III | ME230923 | 0.82 | 0.99 | 1.21 | 0.87 |
FA(17:0) | ME230970 | 0.86 | 0.98 | 1.13 | 0.92 |
11 HDoHE | ME230941 | 0.89 | 0.83 | 1.20 | 0.89 |
FA(18:0) | ME230972 | 0.90 | 0.86 | 1.14 | 1.03 |
15d PGD2 | ME230921 | 0.72 | 0.92 | 1.47 | 0.61 |
FA(23:0) | ME230994 | 0.57 | 0.95 | 1.47 | 0.71 |
FA(22:0) | ME230986 | 0.64 | 0.89 | 1.35 | 0.89 |
FA(24:0) | ME230995 | 0.54 | 0.89 | 1.41 | 0.91 |
11,12-EET | ME230954 | 0.46 | 1.15 | 1.29 | 0.93 |
HXB3 | ME230943 | 0.40 | 1.11 | 1.37 | 0.80 |
PGJ2 | ME230920 | 0.66 | 1.13 | 1.24 | 0.81 |
4 HDoHE | ME230930 | 0.55 | 1.02 | 1.26 | 1.00 |
8,9-EET | ME230953 | 0.58 | 1.05 | 1.23 | 0.97 |
FA(18:4) | ME230977 | 0.97 | 1.16 | 1.14 | 0.42 |
FA(20:1) | ME230979 | 1.23 | 1.13 | 0.98 | 0.54 |
15k PGE2 | ME230909 | 1.08 | 0.67 | 1.08 | 1.14 |
17-HETE | ME230950 | 1.03 | 0.83 | 1.04 | 1.03 |
8-HETE | ME230936 | 1.12 | 0.84 | 1.02 | 1.01 |
FA(18:2) | ME230974 | 1.08 | 0.80 | 1.12 | 0.93 |
FA(18:3 N6) | ME230976 | 0.99 | 0.85 | 1.13 | 0.96 |
11-HETE | ME230916 | 1.18 | 0.82 | 1.08 | 0.85 |
12-HHTrE | ME230915 | 1.19 | 0.84 | 1.15 | 0.70 |
FA(18:3 N3) | ME230975 | 1.11 | 0.88 | 1.14 | 0.75 |
FA(17:1) | ME230971 | 1.09 | 1.02 | 1.09 | 0.72 |
FA(16:0) | ME230968 | 0.99 | 0.98 | 1.09 | 0.86 |
FA(14:0) | ME230966 | 1.16 | 1.01 | 0.98 | 0.83 |
PGD2 | ME230904 | 1.06 | 1.02 | 0.99 | 0.93 |
FA(20:3 N9) | ME230983 | 1.31 | 0.60 | 1.12 | 0.78 |
TxB2 | ME230902 | 1.28 | 0.70 | 1.02 | 1.01 |
15-oxoETE | ME230945 | 1.33 | 0.70 | 1.05 | 0.88 |
dhk PGD2 | ME230912 | 1.36 | 0.75 | 0.99 | 0.89 |
9-HETE | ME230924 | 1.29 | 0.90 | 0.92 | 0.90 |
FA(16:1) | ME230969 | 1.34 | 0.96 | 1.00 | 0.66 |
FA(22:1) | ME230987 | 1.43 | 0.89 | 0.88 | 0.76 |
5,6-diHETrE | ME230959 | 0.88 | 0.71 | 1.36 | 0.84 |
FA(20:3 N6) | ME230982 | 1.28 | 0.74 | 1.23 | 0.55 |
FA(22:4) | ME230990 | 1.32 | 0.73 | 1.20 | 0.58 |
FA(20:2) | ME230980 | 1.25 | 0.72 | 1.21 | 0.62 |
FA(22:5 N6) | ME230992 | 1.23 | 0.72 | 1.27 | 0.57 |
FA(24:1) | ME230996 | 1.13 | 0.81 | 1.25 | 0.62 |
11,12-diHETrE | ME230961 | 1.18 | 0.66 | 1.28 | 0.67 |
20cooh AA | ME230965 | 1.12 | 0.72 | 1.27 | 0.74 |
FA(22:6) | ME230993 | 0.92 | 0.61 | 1.52 | 0.61 |
tetranor 12-HETE | ME230913 | 1.15 | 0.64 | 1.51 | 0.52 |
8,9-diHETrE | ME230960 | 0.97 | 0.72 | 1.39 | 0.65 |
FA(20:4) | ME230984 | 1.10 | 0.66 | 1.40 | 0.55 |
FA(20:5) | ME230985 | 1.15 | 0.66 | 1.38 | 0.54 |
14,15-diHETrE | ME230962 | 1.09 | 0.76 | 1.34 | 0.55 |
FA(22:5 N3) | ME230991 | 1.05 | 0.70 | 1.38 | 0.60 |
11b PGE2 | ME230914 | 1.14 | 1.69 | 0.61 | 0.63 |
19-HETE | ME230948 | 0.48 | 1.88 | 0.77 | 0.88 |
10 HDoHE | ME230937 | 0.78 | 1.52 | 0.85 | 0.77 |
dhk PGE2 | ME230911 | 0.90 | 1.37 | 0.96 | 0.77 |
5,6-EET | ME230952 | 0.32 | 1.36 | 1.24 | 0.95 |
13 HDoHE | ME230918 | 0.56 | 1.34 | 1.28 | 0.75 |
16-HETE | ME230951 | 0.59 | 1.42 | 1.06 | 0.95 |
Factors:
F1 | Diagnosis:Cirrhosis |
F2 | Diagnosis:NASH |
F3 | Diagnosis:Normal |
F4 | Diagnosis:Steatosis |