Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 2:Liver (Study ST000915)

Core I Sphingolipids (Analysis AN001489)

Metabolite	Structure	F1	F2	F3	F4
C14DH HexCer	ME231276	0.31	0.61	2.08	0.29
C26:1 1-deoxyCer	ME231303	1.94	0.58	0.68	0.98
C18:1DH HexCer	ME231278	1.43	1.69	0.65	0.29
C26DH 1-deoxyCer	ME231312	0.73	0.93	0.86	1.71
C26:1 Cer	ME231244	1.07	0.98	1.09	0.78
C20DH Sphingomyelin	ME231289	1.02	1.02	1.05	0.86
C26 Sphingomyelin	ME231265	1.03	1.05	1.05	0.82
C16 GalCer	ME231324	0.96	1.00	1.05	0.96
C24:1 Cer	ME231242	0.99	1.02	1.03	0.94
C22DH HexCer	ME231281	0.95	1.07	1.05	0.88
C16 GlcCer	ME231314	0.96	1.14	1.01	0.87
C16 HexCer	ME231247	0.96	1.14	1.01	0.88
C20 GlcCer	ME231317	0.97	1.14	0.99	0.88
C20 HexCer	ME231250	0.98	1.14	0.99	0.87
C24:1DH Cer	ME231272	1.22	1.19	0.85	0.80
C26 GalCer	ME231332	1.06	1.24	0.89	0.82
C16DH Cer	ME231267	1.11	1.12	0.91	0.89
C24DH HexCer	ME231283	1.13	1.13	0.94	0.80
C20 GalCer	ME231327	1.20	1.07	0.93	0.80
C24:1 GlcCer	ME231319	1.22	1.05	0.92	0.82
C24:1 HexCer	ME231252	1.21	1.05	0.92	0.83
C14 GalCer	ME231323	1.18	0.99	0.93	0.92
C18DH Sphingomyelin	ME231288	1.14	1.04	0.96	0.86
C14DH Sphingomyelin	ME231286	1.30	1.01	0.97	0.70
C26:1 Sphingomyelin	ME231264	1.29	0.96	0.95	0.80
C24:1DH HexCer	ME231282	1.16	1.02	1.04	0.69
C16 Sphingomyelin	ME231257	1.17	0.96	1.02	0.81
C24:1 Sphingomyelin	ME231262	1.19	0.97	1.01	0.80
C18DH HexCer	ME231279	0.94	1.26	1.06	0.64
C26DH Sphingomyelin	ME231292	0.82	1.22	1.18	0.63
C20DH HexCer	ME231280	0.97	1.05	1.28	0.48
C18:1 GlcCer	ME231315	0.93	0.97	1.28	0.61
C18:1 HexCer	ME231248	0.97	0.96	1.24	0.65
C18:1 GalCer	ME231325	1.03	0.93	1.17	0.73
C14 HexCer	ME231246	0.90	1.02	1.20	0.74
C14 Sphingomyelin	ME231256	0.96	1.06	1.13	0.73
C18:1 Cer	ME231238	0.67	1.01	1.09	1.22
C20 Cer	ME231240	0.62	1.01	1.16	1.16
C24 Cer	ME231243	0.55	1.13	1.15	1.11
C18 Cer	ME231239	0.52	1.03	1.16	1.23
C22 Cer	ME231241	0.51	1.08	1.15	1.20
C22 GlcCer	ME231318	0.69	1.13	1.08	1.08
C22 HexCer	ME231251	0.69	1.12	1.08	1.08
C24 GlcCer	ME231320	0.72	1.12	1.07	1.07
C24 HexCer	ME231253	0.72	1.11	1.07	1.07
C20 Sphingomyelin	ME231260	0.75	1.04	1.13	1.01
C22 Sphingomyelin	ME231261	0.75	1.03	1.16	0.98
C18 Sphingomyelin	ME231259	0.85	1.04	1.13	0.89
C24 Sphingomyelin	ME231263	0.85	1.01	1.11	0.95
C20DH Cer	ME231270	0.87	1.12	1.05	0.92
C22DH Sphingomyelin	ME231290	0.83	1.10	1.07	0.96
C24DH Sphingomyelin	ME231291	0.79	1.08	1.11	0.95
C14DH Cer	ME231266	0.88	0.76	1.29	0.90
C14 GlcCer	ME231313	0.79	1.02	1.30	0.68
C18:1 Sphingomyelin	ME231258	0.68	1.15	1.26	0.72
C26 Cer	ME231245	0.66	1.12	1.21	0.89
C14 Cer	ME231236	0.74	0.93	1.23	0.97
C26:1DH Cer	ME231274	0.72	0.94	1.33	0.79
C26DH HexCer	ME231285	0.73	0.97	1.31	0.77
C18:1DH Cer	ME231268	0.76	1.00	1.24	0.85
C18DH Cer	ME231269	0.68	0.98	1.28	0.89
C22 GalCer	ME231328	0.89	0.72	1.17	1.14
C24 GalCer	ME231330	0.75	0.81	1.07	1.35
C16 Cer	ME231237	0.81	0.92	1.03	1.26
C26DH Cer	ME231275	0.79	0.88	1.13	1.16
C26:1DH 1-deoxyCer	ME231311	1.06	1.06	0.78	1.24
C18 GalCer	ME231326	1.06	0.87	1.05	0.98
C16 1-deoxyCer	ME231297	1.05	0.90	0.93	1.18
C24:1 GalCer	ME231329	1.05	0.91	0.94	1.15
Sphingosine-P	ME231296	0.40	1.33	1.21	0.93
C22DH 1-deoxyCer	ME231308	0.35	1.64	0.98	1.05
C18DH 1-deoxyCer	ME231306	0.37	1.45	1.04	1.14
C20DH 1-deoxyCer	ME231307	0.41	1.53	1.00	1.07
C24DH 1-deoxyCer	ME231310	0.40	1.52	1.03	1.03
C16DH 1-deoxyCer	ME231305	0.46	1.65	0.99	0.89
C24:1DH 1-deoxyCer	ME231309	0.66	1.54	0.94	0.88
Sphingosine	ME231295	0.58	1.21	0.97	1.31
C20 1-deoxyCer	ME231299	0.78	1.34	0.77	1.27
C22 1-deoxyCer	ME231300	0.62	1.43	0.83	1.26
C24 1-deoxyCer	ME231302	0.62	1.38	0.83	1.31
C18 1-deoxyCer	ME231298	0.65	1.30	0.91	1.22
Sphinganine	ME231293	0.73	1.37	0.86	1.15
C24:1 1-deoxyCer	ME231301	1.05	1.32	0.76	0.99
C18 GlcCer	ME231316	0.81	1.39	0.96	0.83
C18 HexCer	ME231249	0.83	1.36	0.97	0.84
C26 1-deoxyCer	ME231304	0.87	1.36	0.86	0.98
Sphinganine-P	ME231294	0.80	1.18	1.01	1.01
C22DH Cer	ME231271	0.81	1.28	0.96	0.96
C24DH Cer	ME231273	0.83	1.29	0.95	0.95
C26:1 GalCer	ME231331	1.48	1.13	0.71	0.81
C16DH HexCer	ME231277	1.44	0.90	0.94	0.67
C16DH Sphingomyelin	ME231287	1.47	0.91	0.90	0.75
C26:1 GlcCer	ME231321	0.96	1.46	1.08	0.32
C26:1 HexCer	ME231254	1.03	1.42	1.03	0.38
C26:1DH HexCer	ME231284	1.27	0.84	1.22	0.44
C26 GlcCer	ME231322	1.25	1.09	1.17	0.29
C26 HexCer	ME231255	1.20	1.13	1.10	0.42

Factors:

F1	Diagnosis:Cirrhosis
F2	Diagnosis:NASH
F3	Diagnosis:Normal
F4	Diagnosis:Steatosis

Data matrix