Clustering data with hclust algorithm for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 2:Liver (Study ST000915)
Core H Phospholipids (Analysis AN001490)| Metabolite | Structure | F1 | F2 | F3 | F4 |
|---|---|---|---|---|---|
| LPE(22:6) | ME231401 | 0.38 | 0.65 | 0.66 | 2.88 |
| LPE(20:4) | ME231400 | 0.38 | 0.60 | 0.54 | 3.04 |
| LPE(22:4) | ME231403 | 0.46 | 0.64 | 0.52 | 3.05 |
| LPE(22:5) | ME231402 | 0.49 | 0.60 | 0.48 | 3.00 |
| LPE(18:1) | ME231398 | 0.72 | 0.72 | 0.73 | 2.23 |
| LPE(18:2) | ME231397 | 0.49 | 0.58 | 0.69 | 2.47 |
| PA(34:0) | ME231338 | 0.86 | NA | 0.61 | 1.72 |
| LPI(20:4) | ME231429 | 0.63 | 0.82 | 0.91 | 1.85 |
| LPE(16:0) | ME231396 | 0.73 | 0.75 | 0.94 | 1.82 |
| LPE(18:0) | ME231399 | 0.67 | 0.78 | 0.97 | 1.74 |
| LPC(18:2) | ME231370 | 0.61 | 0.67 | 1.03 | 1.95 |
| LPC(20:4) | ME231373 | 0.51 | 0.59 | 1.00 | 2.05 |
| PG(34:2) | ME231404 | 0.78 | 1.04 | 0.87 | 1.71 |
| BMP(40:7) | ME231411 | 0.67 | 0.84 | 1.09 | 1.41 |
| BMP(40:8) | ME231410 | 0.60 | 0.84 | 1.08 | 1.51 |
| LPC(18:1) | ME231371 | 0.84 | 0.76 | 1.00 | 1.54 |
| LPI(18:0) | ME231428 | 0.74 | 0.85 | 0.96 | 1.56 |
| LPG(18:1) | ME231413 | 0.55 | 1.21 | 1.14 | 1.05 |
| LPG(18:2) | ME231412 | 0.58 | 1.26 | 1.14 | 0.95 |
| PC(36:0e) | ME231357 | 0.92 | 0.82 | 1.34 | 0.89 |
| PE(34:0) | ME231378 | 1.17 | 0.59 | 1.26 | 0.91 |
| PI(36:1) | ME231421 | 1.01 | 0.88 | 0.95 | 1.22 |
| PI(36:4) | ME231418 | 1.05 | 0.84 | 0.95 | 1.23 |
| PI(34:1) | ME231417 | 1.11 | 0.84 | 0.89 | 1.24 |
| PA(36:2) | ME231341 | 1.03 | 0.87 | 0.88 | 1.31 |
| PA(32:2) | ME231333 | 1.10 | 0.88 | 0.87 | 1.30 |
| PA(36:1) | ME231342 | 1.09 | 0.89 | 0.84 | 1.30 |
| PC(36:1e) | ME231356 | 0.86 | 0.80 | 1.08 | 1.28 |
| PC(36:2e) | ME231355 | 0.93 | 0.80 | 1.03 | 1.30 |
| LPC(16:0) | ME231369 | 0.77 | 0.91 | 1.07 | 1.29 |
| PC(38:6) | ME231363 | 0.76 | 0.88 | 1.05 | 1.33 |
| PA(40:6) | ME231345 | 0.77 | 0.92 | 0.95 | 1.35 |
| PE(40:4) | ME231395 | 0.85 | 0.91 | 0.97 | 1.37 |
| BMP(38:5) | ME231409 | 0.66 | 0.97 | 1.05 | 1.34 |
| PA(40:4) | ME231347 | 0.72 | 1.02 | 0.94 | 1.27 |
| PC(36:4) | ME231358 | 0.71 | 1.02 | 1.04 | 1.25 |
| PS(40:6) | ME231440 | 0.69 | 1.03 | 1.11 | 1.13 |
| PC(38:4) | ME231365 | 0.78 | 0.99 | 1.05 | 1.18 |
| PI(38:4) | ME231423 | 0.80 | 1.05 | 1.02 | 1.14 |
| PI(40:4) | ME231427 | 0.83 | 0.95 | 1.01 | 1.25 |
| PA(40:5) | ME231346 | 0.87 | 0.93 | 1.00 | 1.18 |
| PA(38:4) | ME231343 | 0.86 | 1.00 | 0.96 | 1.22 |
| PA(36:4) | ME231339 | 0.83 | 1.00 | 1.01 | 1.18 |
| PI(40:5) | ME231426 | 0.86 | 0.99 | 1.00 | 1.18 |
| PC(40:6) | ME231367 | 0.81 | 0.90 | 1.14 | 1.11 |
| PS(38:6) | ME231436 | 0.83 | 0.87 | 1.16 | 1.06 |
| PI(38:3) | ME231424 | 0.87 | 0.96 | 1.06 | 1.10 |
| BMP(36:2) | ME231408 | 0.85 | 0.89 | 1.10 | 1.12 |
| PE(40:5) | ME231394 | 0.84 | 0.93 | 1.08 | 1.13 |
| PE(40:6) | ME231393 | 0.69 | 0.94 | 1.11 | 1.24 |
| LPC(18:0) | ME231372 | 0.76 | 0.87 | 1.10 | 1.19 |
| BMP(36:3) | ME231407 | 0.81 | 0.92 | 1.08 | 1.19 |
| BMP(36:4) | ME231406 | 0.75 | 0.93 | 1.10 | 1.19 |
| PE(38:6) | ME231386 | 0.76 | 0.95 | 1.09 | 1.16 |
| PC(36:1) | ME231361 | 0.96 | 0.76 | 1.15 | 1.06 |
| PE(36:4) | ME231380 | 0.98 | 1.09 | 0.95 | 1.01 |
| PA(32:1) | ME231334 | 1.00 | 1.03 | 0.91 | 1.14 |
| PC(30:0) | ME231348 | 1.01 | 1.01 | 0.93 | 1.11 |
| PE(38:4) | ME231388 | 0.89 | 1.01 | 1.01 | 1.10 |
| PG(34:1) | ME231405 | 0.90 | 1.01 | 1.02 | 1.06 |
| PS(36:4) | ME231432 | 0.98 | 0.97 | 1.00 | 1.07 |
| PS(40:4) | ME231442 | 0.97 | 0.99 | 1.00 | 1.05 |
| PC(34:2) | ME231353 | 0.93 | 0.97 | 1.00 | 1.11 |
| PA(34:1) | ME231337 | 0.94 | 1.01 | 0.98 | 1.09 |
| PA(36:3) | ME231340 | 0.93 | 1.02 | 0.99 | 1.08 |
| PA(32:0) | ME231335 | 0.96 | 1.02 | 0.96 | 1.10 |
| PA(38:3) | ME231344 | 0.96 | 0.99 | 0.98 | 1.10 |
| PC(36:2) | ME231360 | 0.98 | 0.87 | 1.04 | 1.11 |
| PC(34:1) | ME231354 | 1.00 | 0.87 | 1.04 | 1.09 |
| PC(36:3) | ME231359 | 1.00 | 0.86 | 1.04 | 1.10 |
| PE(40:7) | ME231392 | 0.93 | 0.86 | 1.07 | 1.12 |
| PI(40:6) | ME231425 | 0.95 | 0.85 | 1.05 | 1.14 |
| PC(38:5) | ME231364 | 0.96 | 0.91 | 1.00 | 1.15 |
| PI(36:2) | ME231420 | 1.02 | 0.91 | 0.98 | 1.12 |
| PI(34:2) | ME231416 | 1.09 | 0.87 | 0.98 | 1.09 |
| PE(38:5) | ME231387 | 1.02 | 0.92 | 1.03 | 1.01 |
| PI(32:0) | ME231415 | 1.08 | 0.98 | 0.96 | 1.01 |
| PC(32:2) | ME231349 | 1.05 | 0.92 | 1.09 | 0.85 |
| PS(38:3) | ME231439 | 1.02 | 1.00 | 1.05 | 0.88 |
| PC(38:3) | ME231366 | 0.85 | 0.94 | 1.15 | 0.97 |
| PS(40:5) | ME231441 | 0.84 | 1.00 | 1.11 | 0.99 |
| PE(40:6p) | ME231389 | 0.94 | 0.88 | 1.15 | 0.93 |
| PE(40:5p) | ME231390 | 0.91 | 0.99 | 1.10 | 0.93 |
| PE(38:5p) | ME231384 | 0.91 | 0.94 | 1.11 | 0.95 |
| PC(34:3) | ME231352 | 0.93 | 0.92 | 1.10 | 0.99 |
| PC(40:5) | ME231368 | 0.93 | 0.92 | 1.11 | 0.98 |
| PE(40:4p) | ME231391 | 0.83 | 1.10 | 1.08 | 0.92 |
| PA(34:2) | ME231336 | 0.86 | 1.04 | 1.04 | 1.04 |
| PS(38:4) | ME231438 | 0.86 | 1.09 | 1.03 | 1.00 |
| PE(38:4p) | ME231385 | 1.23 | 0.98 | 1.06 | 0.63 |
| PI(36:3) | ME231419 | 1.42 | 0.74 | 0.89 | 1.01 |
| PI(38:5) | ME231422 | 1.26 | 0.87 | 0.88 | 1.07 |
| PC(32:0) | ME231351 | 1.17 | 0.90 | 0.88 | 1.15 |
| PI(32:1) | ME231414 | 1.17 | 0.88 | 0.89 | 1.14 |
| PS(34:1) | ME231431 | 1.25 | 0.96 | 0.88 | 0.98 |
| PE(34:1) | ME231377 | 1.16 | 0.96 | 0.92 | 1.01 |
| PE(36:1) | ME231383 | 1.17 | 0.93 | 0.92 | 1.03 |
| PE(34:2) | ME231376 | 1.17 | 0.98 | 0.93 | 0.95 |
| PE(36:2) | ME231382 | 1.15 | 1.03 | 0.90 | 0.95 |
| PS(36:1) | ME231435 | 1.16 | 1.01 | 0.89 | 1.00 |
| PE(34:3) | ME231375 | 1.23 | 0.84 | 0.99 | 0.93 |
| PS(34:2) | ME231430 | 1.24 | 0.89 | 0.94 | 0.96 |
| PS(36:3) | ME231433 | 1.30 | 0.89 | 0.91 | 0.93 |
| PC(32:1) | ME231350 | 1.21 | 0.94 | 0.98 | 0.85 |
| PS(38:5) | ME231437 | 1.14 | 0.88 | 1.04 | 0.91 |
| PE(36:4p) | ME231379 | 1.45 | 1.03 | 0.82 | 0.74 |
| PC(38:5e) | ME231362 | 1.29 | 0.92 | 0.93 | 0.85 |
| PE(32:1) | ME231374 | 1.38 | 0.93 | 0.88 | 0.84 |
| PE(36:3) | ME231381 | 1.38 | 0.88 | 0.91 | 0.87 |
| PS(36:2) | ME231434 | 1.36 | 0.90 | 0.92 | 0.84 |
Factors:
| F1 | Diagnosis:Cirrhosis |
| F2 | Diagnosis:NASH |
| F3 | Diagnosis:Normal |
| F4 | Diagnosis:Steatosis |
