Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 2:Plasma (Study ST000916)

Core I Sphingolipids (Analysis AN001495)

Metabolite	Structure	F1	F2	F3	F4
C26:1 1-deoxyCer	ME231817	1.86	0.80	0.77	0.65
C26:1 GlcCer	ME231835	1.83	0.76	0.75	0.76
C24:1DH HexCer	ME231796	1.65	0.73	0.83	0.86
C26:1 HexCer	ME231768	1.70	0.78	0.78	0.83
C24:1 GlcCer	ME231833	1.74	0.85	0.74	0.77
C24:1 HexCer	ME231766	1.67	0.89	0.76	0.78
C24 GlcCer	ME231834	1.64	0.87	0.78	0.80
C24 HexCer	ME231767	1.63	0.87	0.78	0.81
C18DH HexCer	ME231793	1.17	1.04	1.01	0.73
C20DH HexCer	ME231794	1.43	0.95	0.95	0.63
C22 GlcCer	ME231832	1.34	1.02	0.83	0.87
C22 HexCer	ME231765	1.34	1.02	0.83	0.87
C20 GlcCer	ME231831	1.28	1.06	0.87	0.83
C20 HexCer	ME231764	1.27	1.06	0.87	0.84
C16 1-deoxyCer	ME231811	1.44	0.94	0.85	0.82
C26 HexCer	ME231769	1.44	0.97	0.81	0.86
C24DH HexCer	ME231797	1.50	0.88	0.79	0.90
C26 GlcCer	ME231836	1.54	0.90	0.82	0.81
C16DH 1-deoxyCer	ME231819	0.61	1.29	1.16	0.82
C26:1DH 1-deoxyCer	ME231825	0.73	1.48	1.03	0.68
C24:1DH 1-deoxyCer	ME231823	0.66	1.40	1.03	0.87
C26DH 1-deoxyCer	ME231826	0.62	1.46	1.07	0.76
C18DH Sphingomyelin	ME231802	0.56	1.36	0.96	1.16
C24:1DH Cer	ME231786	0.73	1.28	0.91	1.15
C18DH Cer	ME231783	0.66	1.38	0.95	1.05
C24:1 Cer	ME231756	0.67	1.25	1.00	1.09
C24 Sphingomyelin	ME231777	0.66	1.28	1.02	1.02
C26 Sphingomyelin	ME231779	0.67	1.27	1.03	1.02
C18 1-deoxyCer	ME231812	0.56	1.11	1.10	1.20
Sphinganine-P	ME231810	0.61	1.12	1.07	1.18
C22 1-deoxyCer	ME231814	0.68	1.14	1.01	1.18
C24 1-deoxyCer	ME231816	0.63	1.15	1.02	1.22
C18:1 Sphingomyelin	ME231772	0.51	1.17	1.12	1.15
C24DH Sphingomyelin	ME231805	0.53	1.22	1.06	1.18
C20 Sphingomyelin	ME231774	0.50	1.22	1.10	1.15
C22DH Sphingomyelin	ME231804	0.49	1.25	1.07	1.19
C24 Cer	ME231757	0.46	1.24	1.10	1.17
C20 Cer	ME231754	0.59	1.28	1.07	1.03
C18 Sphingomyelin	ME231773	0.53	1.27	1.09	1.06
C26DH Sphingomyelin	ME231806	0.54	1.27	1.08	1.09
C22 Cer	ME231755	0.49	1.33	1.07	1.08
C22 Sphingomyelin	ME231775	0.51	1.31	1.08	1.06
C24:1 GalCer	ME231843	0.31	1.52	1.15	0.92
C18 Cer	ME231753	0.45	1.39	1.05	1.08
C24DH 1-deoxyCer	ME231824	0.45	1.41	1.09	1.00
C22DH 1-deoxyCer	ME231822	0.36	1.43	1.11	1.05
C18DH 1-deoxyCer	ME231820	0.32	1.34	1.16	1.11
C20DH 1-deoxyCer	ME231821	0.39	1.35	1.13	1.07
C26:1 GalCer	ME231845	0.85	0.90	0.97	1.39
Sphingosine	ME231807	0.64	0.87	1.09	1.41
Sphingosine-P	ME231809	0.61	1.00	1.08	1.31
C26:1DH HexCer	ME231798	1.26	0.63	0.95	1.24
C26DH HexCer	ME231799	1.17	0.70	1.10	0.96
C14DH HexCer	ME231790	1.21	0.86	0.99	0.93
C16DH HexCer	ME231791	1.17	0.90	1.01	0.89
C26DH Cer	ME231789	1.15	0.81	0.95	1.13
C14DH Cer	ME231780	1.09	0.82	1.03	1.06
C18:1DH HexCer	ME231792	1.07	0.86	1.05	0.98
C22 GalCer	ME231842	1.11	1.08	0.82	1.12
C24 GalCer	ME231844	1.21	1.18	0.73	1.03
C26 1-deoxyCer	ME231818	1.26	1.12	0.73	1.03
C14 GalCer	ME231837	0.82	1.09	1.18	0.79
C18 GalCer	ME231840	0.91	1.27	1.00	0.78
C16 GalCer	ME231838	0.86	1.34	0.87	1.00
C22DH Cer	ME231785	0.85	1.26	0.90	1.05
C24DH Cer	ME231787	0.91	1.16	0.87	1.15
C26 GalCer	ME231846	0.95	1.28	0.79	1.12
C24:1 1-deoxyCer	ME231815	0.94	1.13	0.95	1.01
Sphinganine	ME231808	0.93	1.10	0.94	1.07
C24:1 Sphingomyelin	ME231776	0.88	1.07	1.03	1.00
C26:1 Cer	ME231758	0.87	1.03	1.02	1.09
C18:1 GlcCer	ME231829	0.93	1.06	0.99	1.04
C18:1 HexCer	ME231762	0.92	1.07	0.99	1.04
C14DH Sphingomyelin	ME231800	0.88	1.09	0.98	1.08
C14 Sphingomyelin	ME231770	0.89	1.06	0.99	1.07
C18:1 GalCer	ME231839	0.78	1.21	0.97	1.06
C20DH Sphingomyelin	ME231803	0.79	1.16	1.00	1.06
C26 Cer	ME231759	0.74	1.03	1.07	1.15
C20 1-deoxyCer	ME231813	0.77	1.10	1.02	1.12
C18:1 Cer	ME231752	0.81	1.08	1.01	1.10
C18:1DH Cer	ME231782	0.84	1.07	0.99	1.11
C26:1DH Cer	ME231788	0.99	0.97	0.98	1.09
C26:1 Sphingomyelin	ME231778	1.02	1.01	0.97	1.00
C14 Cer	ME231750	0.93	1.00	1.04	1.00
C14 GlcCer	ME231827	1.01	1.02	1.02	0.92
C14 HexCer	ME231760	0.99	1.03	1.04	0.91
C20DH Cer	ME231784	0.91	1.16	0.97	0.96
C18 GlcCer	ME231830	0.95	1.17	0.99	0.89
C18 HexCer	ME231763	0.95	1.18	0.99	0.88
C22DH HexCer	ME231795	1.06	1.14	0.92	0.90
C16 Sphingomyelin	ME231771	1.05	1.08	0.96	0.92
C16 GlcCer	ME231828	1.11	1.08	0.94	0.89
C16 HexCer	ME231761	1.10	1.08	0.94	0.89
C20 GalCer	ME231841	1.06	1.11	0.88	1.02
C16DH Sphingomyelin	ME231801	1.00	1.08	0.94	1.01
C16 Cer	ME231751	1.00	1.13	0.94	0.95
C16DH Cer	ME231781	1.01	1.14	0.91	0.99

Factors:

F1	Diagnosis:Cirrhosis
F2	Diagnosis:NASH
F3	Diagnosis:Normal
F4	Diagnosis:Steatosis

Data matrix