Clustering data with hclust algorithm for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 3:Urine (Study ST000917)
Core G Fatty acids/Eicosanoids (Analysis AN001497)| Metabolite | Structure | F1 | F2 | F3 | F4 |
|---|---|---|---|---|---|
| 9,10 diHOME | ME231930 | 3.23 | 0.26 | 0.09 | 0.16 |
| 12,13 diHOME | ME231931 | 2.23 | 0.48 | 0.42 | 0.37 |
| LTE4 | ME231927 | 2.59 | 0.59 | 0.48 | 0.45 |
| PGF3a | ME231919 | 2.59 | 0.90 | 0.35 | 0.35 |
| FA(20:0) | ME231945 | 0.22 | 0.33 | 0.50 | 3.57 |
| FA(22:0) | ME231953 | 0.32 | 0.34 | 0.36 | 3.74 |
| FA(20:1) | ME231946 | 0.09 | 0.29 | 1.16 | 3.30 |
| FA(22:5 N6) | ME231959 | 0.31 | 0.16 | 0.98 | 3.33 |
| FA(26:0) | ME231964 | 0.15 | 1.30 | 0.32 | 3.02 |
| FA(22:3) | ME231956 | 0.60 | 0.68 | 0.27 | 3.00 |
| FA(24:0) | ME231962 | 0.38 | 0.65 | 0.46 | 2.93 |
| FA(18:0) | ME231939 | 0.29 | 0.62 | 0.80 | 3.00 |
| FA(24:1) | ME231963 | 0.53 | 0.50 | 0.67 | 2.87 |
| FA(23:0) | ME231961 | 0.79 | 0.69 | 0.52 | 2.21 |
| FA(22:1) | ME231954 | 1.19 | 0.45 | 0.57 | 2.24 |
| FA(22:2) | ME231955 | 1.21 | 0.44 | 0.62 | 2.24 |
| FA(14:0) | ME231933 | 0.53 | 0.49 | 1.27 | 1.70 |
| FA(20:3 N3) | ME231948 | 0.73 | 0.30 | 1.30 | 1.82 |
| FA(15:0) | ME231934 | 0.64 | 0.53 | 0.80 | 2.22 |
| FA(17:0) | ME231937 | 0.52 | 0.64 | 0.97 | 2.26 |
| FA(16:0) | ME231935 | 0.32 | 0.72 | 1.10 | 2.15 |
| FA(20:3 N9) | ME231950 | 0.54 | 0.57 | 1.18 | 2.01 |
| FA(20:4) | ME231951 | 0.12 | 0.20 | 1.53 | 2.13 |
| FA(20:3 N6) | ME231949 | 0.16 | 0.08 | 1.31 | 2.81 |
| FA(22:5 N3) | ME231958 | 0.49 | 0.35 | 1.11 | 2.32 |
| FA(22:6) | ME231960 | 0.43 | 0.31 | 1.04 | 2.55 |
| FA(20:2) | ME231947 | 0.21 | 0.30 | 1.10 | 2.55 |
| FA(22:4) | ME231957 | 0.22 | 0.26 | 1.14 | 2.50 |
| FA(20:5) | ME231952 | 0.33 | 2.24 | 1.05 | 1.03 |
| 11b PGF2a | ME231918 | 0.82 | 2.00 | 0.42 | 0.53 |
| dhk PGE2 | ME231921 | 0.87 | 1.87 | 0.45 | 1.02 |
| 13-HODE | ME231928 | 0.51 | 1.33 | 0.92 | 1.35 |
| FA(18:3 N3) | ME231942 | 0.52 | 1.45 | 1.06 | 1.20 |
| 9-HODE | ME231929 | 0.67 | 1.47 | 0.63 | 1.41 |
| FA(18:4) | ME231944 | 0.95 | 1.25 | 0.78 | 1.24 |
| 2,3 dinor 8-iso PGF2a | ME231932 | 1.12 | 1.00 | 0.84 | 1.14 |
| dhk PGD2 | ME231922 | 1.16 | 0.75 | 1.02 | 1.06 |
| 8-iso PGF2a III | ME231926 | 1.33 | 1.14 | 0.83 | 0.78 |
| 5-iso PGF2a VI | ME231925 | 1.72 | 0.85 | 0.62 | 0.98 |
| dhk PGF2a | ME231920 | 1.49 | 0.93 | 0.67 | 1.05 |
| PGFM | ME231923 | 0.37 | 0.53 | 2.05 | 0.44 |
| FA(16:1) | ME231936 | 0.21 | 0.63 | 1.44 | 1.54 |
| FA(17:1) | ME231938 | 0.30 | 0.33 | 1.70 | 1.30 |
| PGEM | ME231924 | 0.80 | 0.79 | 1.57 | 0.62 |
| FA(18:1) | ME231940 | 0.59 | 0.81 | 1.26 | 1.28 |
| FA(18:2) | ME231941 | 0.41 | 1.06 | 1.34 | 1.10 |
| FA(18:3 N6) | ME231943 | 0.55 | 1.04 | 1.39 | 0.89 |
Factors:
| F1 | Diagnosis:Cirrhosis |
| F2 | Diagnosis:NASH |
| F3 | Diagnosis:Normal |
| F4 | Diagnosis:Steatosis |
