Clustering data with hclust algorithm for Metabolomic profiles in healthy research cats receiving clindamycin with a synbiotic or a placebo: a randomized, controlled trial (Part II) (Study ST000981)

GC POSITIVE ION MODE (Analysis AN001607)
MetaboliteStructureF1F2F3F4F5F6F7F8F9F10F11F12F13F14F15F16F17F18F19F20F21F22F23F24F25F26
glyceric acidME2415980.290.310.330.170.380.090.150.130.100.080.140.100.100.240.120.2544.070.150.130.120.130.130.060.190.190.10
1-kestoseME2417051.740.010.020.030.080.060.833.530.100.010.010.000.080.010.010.010.030.010.216.8818.200.180.010.110.030.02
cellobioseME2416360.661.141.352.620.551.9916.543.270.570.110.200.050.380.220.232.520.390.570.790.240.270.430.230.070.360.21
mannoseME2415521.270.240.090.090.390.321.245.200.460.260.180.050.090.020.020.090.060.290.2113.490.042.070.240.370.040.13
melezitoseME2415510.520.060.060.040.070.098.556.031.030.050.060.020.410.020.100.060.040.090.1611.083.082.320.190.440.070.03
norvalineME2415320.630.880.450.720.703.840.080.140.257.490.9610.830.090.300.671.220.100.580.590.050.160.120.280.160.350.52
sucroseME2414870.740.040.090.220.150.054.353.600.230.050.060.0010.590.160.010.100.660.070.331.236.810.310.000.380.050.09
3,4-dihydroxyphenylacetic acidME2416800.420.941.160.590.660.890.120.220.374.560.910.840.390.370.280.741.860.380.590.260.390.6210.630.520.091.74
5,6-dihydrouracil majorME2416650.710.281.214.041.3610.410.270.290.550.310.420.340.400.823.310.680.600.360.750.310.271.081.550.230.691.35
isomaltoseME2415751.600.010.030.050.190.205.526.110.110.020.020.010.220.020.000.010.080.130.054.289.440.660.010.060.010.01
sophoroseME2414921.440.060.170.140.980.605.025.180.080.110.050.050.550.160.030.150.330.240.153.179.990.560.040.050.090.09
lactoseME2415690.560.240.161.511.191.3310.355.510.340.050.040.020.070.150.040.442.010.390.285.047.180.510.020.040.090.10
galactinolME2416090.900.070.090.170.140.0810.565.051.610.030.040.030.100.290.060.090.160.040.576.7511.200.200.110.120.070.03
raffinoseME2415001.200.010.010.020.050.049.666.210.420.010.010.010.050.010.030.000.020.010.154.6012.680.030.030.070.010.03
maltitolME2415561.520.260.490.280.680.378.742.400.920.750.200.130.520.070.100.750.160.400.451.583.101.160.170.990.400.36
gluconic acidME2416041.170.430.370.870.620.337.435.980.550.380.170.120.520.410.300.241.310.160.153.812.590.970.140.390.050.16
guanosineME2415901.060.280.960.630.320.165.474.141.460.100.070.130.040.130.080.130.771.120.454.072.971.680.080.090.060.30
inosineME2415780.860.381.900.310.400.334.174.711.900.060.070.460.070.590.160.140.831.361.131.732.161.700.030.290.060.29
maltotriitolME2415541.390.040.200.462.801.364.633.223.570.040.050.060.650.120.030.090.600.620.022.375.740.420.200.260.030.08
beta-mannosylglycerateME2416431.140.490.320.430.740.511.882.521.200.650.380.100.230.340.350.180.370.680.871.416.551.950.480.650.280.79
galactoseME2416071.580.340.240.450.240.274.652.970.830.640.480.530.630.050.500.400.100.460.780.086.151.210.651.060.090.36
palatinitolME2415231.470.170.190.520.620.685.862.811.510.210.320.100.090.030.100.220.190.651.432.586.971.010.090.920.050.10
glycerol-3-galactosideME2415961.150.180.330.341.740.752.626.610.720.200.210.180.830.460.190.470.990.201.011.125.890.920.160.590.290.14
maltotrioseME2415530.980.060.470.611.670.652.763.931.310.110.090.150.271.350.060.284.760.141.030.845.652.070.110.260.030.23
2-deoxyerythritolME2416960.346.519.050.762.110.260.050.110.700.380.220.150.220.960.360.771.880.250.300.080.180.530.500.530.270.39
1-hexadecanolME2417060.600.330.330.290.500.370.110.100.610.200.120.130.110.130.880.370.384.6312.590.120.120.660.170.180.100.34
octadecanolME2415300.720.650.680.340.500.340.220.220.420.440.320.190.300.280.520.660.422.959.430.220.361.500.420.340.250.94
homovanillic acidME2415841.160.252.931.640.180.220.080.060.170.800.110.130.220.290.160.200.790.406.860.120.152.050.073.030.261.55
ferulic acidME2416130.971.051.493.911.811.280.070.110.120.341.200.150.670.550.261.291.340.5011.000.080.070.181.153.080.490.37
cis-sinapinic acidME2416300.930.250.690.830.870.590.130.702.600.161.410.190.600.190.061.490.800.347.820.080.433.380.281.000.770.38
cholic acidME2416320.880.010.352.511.300.030.350.394.250.050.840.011.460.800.010.220.890.2411.300.880.382.002.031.570.010.21
sinapinic acidME2414930.560.370.872.931.461.400.111.503.110.330.930.170.630.530.110.100.360.389.710.140.312.430.361.410.710.52
2,8-dihydroxyquinolineME2416970.900.400.931.080.520.351.831.359.290.300.350.130.400.160.250.630.400.245.401.370.562.800.200.270.250.20
glucoheptuloseME2416051.580.290.311.400.743.230.224.248.380.250.610.100.460.440.060.230.310.361.610.230.150.230.161.960.440.22
norleucineME2415330.562.810.531.121.295.051.920.060.140.510.960.291.070.331.040.936.410.780.202.710.060.130.205.621.340.33
4-hydroxyhippuric acid NISTME2416680.332.922.761.003.771.830.250.162.090.250.280.300.120.941.290.949.960.321.080.280.231.050.051.180.370.45
maltoseME2415551.110.401.570.763.382.722.171.450.190.230.150.180.622.680.161.186.010.360.070.804.350.200.050.140.730.29
beta-glutamic acidME2416440.420.030.050.010.400.000.070.030.260.060.010.430.020.430.110.020.230.098.030.060.009.260.020.020.030.20
3-hydroxypalmitic acidME2416750.310.700.220.390.470.830.130.140.290.460.280.330.070.100.710.500.241.010.780.290.147.250.680.090.181.24
alpha-ketoglutarateME2416540.580.630.770.990.340.260.060.041.010.420.160.290.111.500.311.390.940.491.920.040.057.220.060.090.190.44
3-hydroxy-3-methylglutaric acidME2416770.561.392.594.011.490.440.210.120.280.710.860.670.512.008.051.012.760.180.960.230.160.243.181.010.571.02
phenylethylamineME2415130.530.171.070.820.970.230.791.092.492.340.952.080.191.048.350.790.160.631.000.600.810.501.250.361.061.53
3,4-dihydroxycinnamic acidME2416820.940.421.052.091.871.110.351.030.270.500.420.185.980.500.100.760.690.254.520.540.430.240.683.720.380.53
2-hydroxyglutaric acidME2416920.840.781.242.171.060.792.700.501.400.130.600.090.774.520.541.010.860.180.304.141.022.090.592.161.330.34
2-methylglyceric acid NISTME2416880.580.630.820.452.010.634.050.271.500.211.990.912.461.070.420.341.640.420.675.480.240.201.532.500.781.14
succinic acidME2414880.760.100.110.361.280.684.430.311.670.012.230.982.731.450.010.180.090.310.336.390.290.151.602.792.931.16
3-hydroxypropionic acidME2416730.860.140.671.281.130.190.110.243.110.313.210.114.120.820.200.810.040.180.370.120.181.642.662.183.780.30
3-phenyllactic acidME2416720.880.190.821.440.950.510.390.371.881.051.720.233.064.130.401.040.090.130.310.541.050.223.343.573.650.79
p-hydroxylphenyllactic acidME2415100.810.210.340.740.780.350.420.290.680.932.300.403.862.600.100.100.170.152.200.620.300.775.573.091.381.02
butane-2,3-diol NISTME2416401.130.400.300.380.370.410.280.500.370.544.920.264.410.610.170.360.130.270.270.360.780.525.850.862.050.43
N-acetylputrescineME2415370.360.280.780.470.590.391.661.681.230.831.090.254.320.241.360.380.381.330.431.321.200.635.770.160.281.25
creatinineME2416261.223.120.870.620.820.791.420.472.210.200.330.240.730.050.590.341.590.390.470.353.470.390.100.495.621.12
3-(3-hydroxyphenyl)propionic acidME2416850.752.862.411.251.831.550.000.000.002.890.150.030.010.003.112.652.742.050.030.000.000.013.390.010.010.09
3-hydroxyphenylacetic acidME2416740.731.850.350.120.160.380.010.040.084.880.100.090.070.250.800.161.854.680.410.040.020.520.400.090.160.14
1-methyladenosineME2417040.820.392.093.594.190.372.331.000.830.220.940.201.800.210.220.482.580.171.822.531.080.370.232.151.240.29
taurineME2414850.304.471.650.842.761.290.060.092.220.540.072.220.072.120.120.053.130.430.080.030.313.630.040.520.360.27
thymidineME2414810.351.742.903.051.643.280.210.090.490.940.462.110.111.080.280.773.220.810.820.220.151.750.561.420.201.10
citric acidME2416293.041.423.070.621.290.230.100.050.260.100.040.090.040.360.470.202.600.110.710.100.080.240.060.250.130.15
uric acidME2414660.934.221.670.460.760.150.200.360.560.430.190.520.340.930.940.995.631.710.240.070.890.110.430.112.760.79
2,3-dihydroxybutanoic acid NISTME2417000.701.602.822.123.120.630.210.210.870.180.410.580.585.180.620.994.540.420.610.020.510.260.472.552.500.59
parabanic acid NISTME2415190.771.121.650.382.110.340.530.461.000.410.520.890.263.240.270.495.770.410.810.160.632.180.671.631.050.77
isothreonic acidME2415730.822.411.621.493.290.840.870.410.860.170.400.410.771.870.590.605.280.281.900.550.911.280.461.230.290.42
pseudo uridineME2415030.652.232.110.922.590.670.150.260.420.600.410.790.301.610.640.984.951.190.690.300.340.490.551.741.791.08
threonic acidME2414831.581.491.390.992.600.220.900.600.890.210.700.231.200.880.410.554.340.290.690.640.650.490.401.032.250.35
sorbitolME2414910.980.320.400.460.740.590.552.080.740.273.320.285.410.410.120.480.810.250.962.180.571.030.380.522.500.24
daidzeinME2416220.840.100.640.961.060.201.781.500.580.380.870.212.370.290.180.580.540.140.411.561.763.620.372.912.090.27
conduritol-beta-epoxideME2416270.880.100.260.450.710.130.531.130.490.272.220.104.810.390.070.220.110.100.040.231.392.800.012.403.840.64
pinitolME2415081.200.050.260.361.570.030.682.020.520.141.370.043.920.220.030.220.240.030.040.021.553.120.042.102.310.23
lactamideME2415710.780.030.230.260.550.063.143.681.260.153.560.043.510.450.040.220.020.030.452.824.520.980.251.742.030.12
cystineME2416241.110.160.270.390.471.122.743.060.621.010.810.112.410.530.210.260.560.452.280.671.461.791.430.870.810.37
ornithineME2415261.210.570.650.170.560.761.711.891.030.471.380.523.170.290.460.320.350.760.401.800.900.992.030.100.210.90
melibioseME2415501.770.050.120.070.920.802.144.920.560.051.050.041.500.040.070.020.220.440.152.472.231.160.080.07NA0.10
galactonic acidME2416080.900.640.490.830.940.964.263.750.710.500.930.391.130.590.731.100.300.290.672.221.491.161.461.081.210.66
glucoseME2416031.940.660.650.921.101.402.932.590.190.670.460.140.630.320.120.730.850.390.202.252.920.450.150.320.330.33
UDP-glucuronic acidME2414690.761.100.742.891.681.422.352.130.441.090.960.480.990.620.220.560.410.500.342.313.201.130.371.970.800.57
N-methylalanineME2415350.811.370.930.830.740.810.040.471.252.870.593.820.102.012.631.120.261.870.530.330.070.390.200.060.271.16
2,4-diaminobutyric acidME2416990.981.340.880.980.632.010.110.120.132.311.284.940.210.631.071.690.211.440.190.130.090.150.880.250.361.63
piperidoneME2415060.801.630.771.350.682.630.010.020.082.210.485.950.040.921.951.030.021.190.090.020.010.100.870.030.222.42
3,4-dihydroxyhydrocinnamic acid NISTME2416810.490.280.430.440.180.450.370.360.620.092.772.750.700.480.210.360.020.240.690.410.340.610.121.730.985.08
tyrosolME2414700.460.650.800.600.320.510.040.110.432.090.492.730.080.580.980.760.550.902.190.060.260.990.370.200.274.16
4-aminobutyric acidME2416711.460.130.210.182.830.400.821.825.050.840.710.270.781.160.440.130.650.090.222.341.400.892.550.720.390.51
butyrolactam NISTME2416391.410.310.400.370.270.480.892.294.300.980.841.120.811.480.190.350.150.400.612.361.520.931.950.870.550.75
2-hydroxybutanoic acidME2416931.280.651.561.131.250.170.231.283.841.381.630.371.162.240.211.060.210.061.250.900.610.910.330.700.770.82
histidineME2415861.181.130.750.270.790.290.221.094.460.680.940.661.901.020.540.441.250.820.530.090.192.350.290.250.700.36
1,5-anhydroglucitolME2417070.360.190.200.221.001.150.480.462.070.600.940.110.860.110.130.170.280.162.480.580.522.990.170.240.433.93
pentitolME2415160.940.710.380.730.500.580.820.403.240.521.730.360.831.640.140.560.290.264.040.820.543.370.290.961.550.43
adenosineME2416591.440.260.930.861.430.250.991.091.990.340.150.070.420.110.120.651.860.492.520.682.063.180.250.240.150.18
levoglucosanME2415660.860.720.480.870.710.661.040.463.121.600.920.130.600.540.101.780.660.331.200.490.833.310.040.850.791.08
ureaME2414671.100.681.512.142.510.031.271.332.350.020.030.760.171.190.340.031.540.522.031.412.420.990.011.702.800.58
ribitolME2414990.931.341.300.901.541.130.730.461.090.590.840.431.041.570.330.833.060.554.310.410.501.230.171.492.400.50
erythritolME2416160.831.031.261.761.850.950.810.582.530.250.820.351.012.460.280.752.290.292.620.920.502.110.211.911.530.30
ribonic acidME2414980.930.710.931.612.571.941.530.581.630.190.860.241.021.490.220.452.570.262.590.981.461.650.411.170.540.66
tyramineME2414720.540.741.081.480.581.691.491.403.061.161.000.790.211.552.391.370.210.813.691.201.271.320.130.621.110.88
pyruvic acidME2415010.900.401.152.551.180.252.351.473.020.820.770.231.750.530.300.961.190.273.503.212.120.910.140.870.760.42
n-acetyl-d-hexosamineME2415411.000.810.911.081.591.761.291.920.280.950.720.221.750.470.190.981.520.393.160.913.331.011.051.080.540.38
beta-gentiobioseME2416451.800.220.270.590.510.541.392.101.630.740.150.141.040.400.090.420.340.293.071.723.211.360.190.690.150.52
methanolphosphateME2415491.170.380.610.120.180.881.531.321.510.901.400.710.910.110.731.300.201.293.031.491.990.840.171.631.570.60
allantoic acidME2416551.111.192.110.744.030.060.920.732.110.090.570.050.683.320.861.181.570.990.100.610.910.290.050.462.670.26
malic acidME2415581.271.011.470.971.481.880.500.280.450.350.760.340.794.250.300.311.340.700.550.740.260.601.050.732.431.15
hexitolME2415871.131.070.900.660.851.130.081.290.860.380.540.831.104.630.380.301.480.860.482.000.181.830.170.981.200.47
N-acetylglutamateME2415390.640.950.990.641.141.620.350.210.851.070.381.432.045.380.701.221.810.531.040.540.361.780.831.550.650.94
myo-inositolME2415451.460.311.000.561.020.400.602.910.960.601.100.502.453.930.230.430.670.210.150.170.251.080.301.831.900.18
N-acetyl-D-mannosamineME2415401.211.011.040.760.751.610.311.721.011.161.730.291.502.390.082.150.640.600.130.580.130.930.151.131.000.75
lyxitolME2415610.941.171.181.032.200.621.450.521.130.231.290.453.152.830.400.203.030.360.741.201.290.510.542.012.160.24
xylitolME2414600.691.111.010.331.490.372.070.590.621.431.540.333.651.140.410.642.110.410.831.111.620.641.521.310.571.04
adenineME2416600.910.722.182.062.510.630.470.390.281.650.970.501.331.100.722.024.080.410.140.740.860.131.402.551.680.53
fructoseME2416121.550.600.951.152.541.440.660.150.071.001.090.072.280.120.300.892.430.740.230.210.740.160.742.350.500.69
propane-1,3-diol NISTME2415041.170.070.400.501.330.101.611.051.390.311.680.164.300.660.060.140.050.140.901.732.220.891.722.043.880.28
2-hydroxyhexanoic acidME2416911.260.091.021.330.990.221.201.501.270.951.620.152.072.490.201.080.140.050.801.432.361.131.101.512.350.26
lactic acidME2415701.450.010.560.721.830.052.102.081.710.351.410.033.021.100.010.430.010.010.552.512.880.440.552.032.010.21
oleamide NISTME2415280.970.790.560.790.570.242.680.640.770.491.800.191.290.790.781.020.951.340.570.403.740.840.321.171.640.98
phosphateME2415121.111.941.820.570.930.380.921.201.730.350.840.630.801.930.230.340.750.622.270.901.740.690.203.240.690.74
erythroseME2416150.790.811.201.401.321.661.661.291.570.622.570.362.021.100.310.840.830.420.600.702.260.770.642.251.270.59
glycerol-alpha-phosphateME2415950.770.790.901.951.411.650.691.031.720.631.240.631.481.330.380.690.760.670.910.932.061.390.612.531.180.72
lanosterolME2415680.990.510.854.011.100.060.580.220.990.550.790.850.071.730.160.721.182.220.100.950.491.460.211.380.020.91
N-acetylaspartic acidME2415431.371.672.763.781.840.890.150.250.150.671.040.490.962.200.601.250.730.300.620.450.200.520.550.940.890.62
xyloseME2414581.771.471.153.800.840.960.730.180.231.091.940.150.480.080.141.560.590.680.210.240.310.920.690.780.190.50
galacturonic acidME2416061.180.612.813.141.410.161.752.930.310.080.400.070.160.110.412.291.160.320.381.432.021.701.500.060.340.14
xylulose NISTME2414571.120.961.164.470.850.672.672.180.851.001.470.110.840.150.131.701.080.620.191.531.940.670.740.490.230.40
2^-deoxyguanosineME2416950.970.533.292.011.740.401.171.050.580.910.900.360.410.270.693.042.521.020.111.530.710.540.470.050.600.78
ketohexoseME2415721.440.691.181.602.041.280.821.451.000.631.170.370.620.500.282.801.650.391.260.851.320.800.540.330.480.47
tagatoseME2414861.270.451.041.412.340.212.671.250.880.331.670.311.360.440.842.462.250.321.110.611.130.760.471.540.430.35
2-hydroxyvaleric acidME2416900.962.001.810.491.990.310.040.660.390.340.220.391.190.400.460.352.081.640.310.071.310.613.362.080.280.80
O-acetylserineME2415310.820.781.252.621.071.151.381.271.690.880.720.890.930.750.210.730.400.821.211.101.090.884.740.680.330.93
lyxoseME2415601.942.780.461.470.321.500.350.100.161.682.800.080.130.140.072.691.050.390.290.150.150.701.300.340.020.32
inositol-4-monophosphateME2415770.375.421.441.011.210.810.290.480.810.660.390.400.161.731.590.633.221.780.650.270.270.640.800.290.221.20
3-(4-hydroxyphenyl)propionic acidME2416840.792.741.431.251.101.270.080.130.351.270.530.670.260.531.832.872.832.400.590.110.110.261.080.370.290.62
phosphoethanolamineME2415110.873.152.331.322.451.450.300.310.650.590.391.390.331.550.572.141.281.240.890.260.270.640.250.440.550.64
xanthineME2414611.264.161.240.930.472.070.020.070.430.950.470.960.091.580.531.490.671.640.280.160.030.360.600.280.640.99
putrescineME2415020.461.171.602.281.423.060.190.471.171.300.610.050.340.734.102.110.542.170.030.640.130.840.300.920.860.76
orotic acidME2415250.651.501.360.791.544.750.130.080.181.690.690.310.501.960.681.611.591.920.340.160.070.280.670.700.271.44
glycyl-prolineME2415920.690.640.871.351.362.461.571.440.240.860.510.850.570.362.330.210.052.570.140.731.330.990.240.360.590.86
4-hydroxybutyric acidME2416691.171.620.861.512.544.380.861.181.060.580.580.210.580.640.621.090.990.661.031.151.230.850.660.490.590.42
tryptophanME2414730.981.781.001.541.353.390.891.180.101.171.290.981.130.262.230.391.450.590.260.791.150.341.560.040.901.04
beta-alanineME2416460.960.581.280.260.370.300.030.050.662.470.572.630.090.313.042.110.520.840.160.040.040.262.800.090.462.78
3,4-dihydroxybenzoic acidME2416830.640.871.401.141.141.050.320.230.433.221.461.020.270.410.491.462.100.390.230.310.310.292.740.740.362.72
4-hydroxyphenylacetic acidME2416670.691.321.131.220.832.350.050.110.481.900.861.520.190.341.151.471.430.300.700.100.091.401.350.400.492.71
deoxycholic acidME2416210.541.721.350.770.680.060.000.000.021.591.780.030.070.060.180.680.243.730.200.000.030.010.040.120.002.52
isopentadecanoic acidME2415740.861.870.880.820.610.860.670.551.000.332.650.371.000.531.761.150.912.610.210.490.530.460.270.450.660.62
hydrocinnamic acidME2415830.741.420.700.250.490.120.260.450.320.440.500.510.560.110.600.610.485.390.370.440.240.160.200.530.520.72
glutamineME2416001.601.380.700.600.601.740.250.170.610.510.480.881.191.000.990.350.582.220.410.140.200.580.210.280.330.86
pentadecanoic acidME2415171.062.581.150.880.731.050.550.630.220.490.330.270.280.401.521.140.753.150.390.420.490.390.350.380.230.73
biphenylME2416410.641.470.670.770.451.140.550.401.252.040.530.570.650.210.820.200.362.960.370.540.521.190.370.100.311.38
pipecolinic acidME2415070.830.831.180.640.841.320.460.260.851.370.291.050.370.372.430.630.542.940.320.240.400.970.640.340.471.07
palmitoleic acidME2415210.750.700.320.260.300.760.640.740.460.400.510.250.200.421.090.510.434.240.800.170.290.680.330.280.201.73
D-erythro-sphingosineME2416201.320.510.450.150.300.320.250.550.320.910.730.240.870.280.690.510.273.780.320.220.110.470.370.070.221.13
phytosphingosineME2415091.440.560.520.290.470.280.890.660.370.650.410.221.140.330.610.640.213.090.440.310.790.660.400.190.221.02
linoleic acidME2415641.191.710.690.500.730.650.711.050.650.950.900.890.560.750.910.730.662.070.960.830.190.460.870.700.490.99
octadecylglycerolME2415290.891.240.750.550.490.750.490.750.561.080.531.140.350.730.761.030.672.700.480.830.850.530.960.330.321.56
arachidonic acidME2416510.850.570.560.520.530.820.610.780.720.490.630.730.490.730.710.430.322.371.390.520.291.780.800.490.371.62
myristic acidME2415440.880.730.460.370.390.500.760.890.790.710.820.430.510.680.650.670.442.911.040.500.501.220.680.620.441.35
dihydrocholesterolME2416180.650.860.520.540.220.090.240.280.571.140.660.690.390.761.200.350.253.261.540.340.201.331.700.410.311.59
docosahexaenoic acidME2416170.510.700.570.470.520.830.370.230.431.480.910.810.370.570.250.490.453.521.450.100.320.891.210.460.091.87
3-aminoisobutyric acidME2416780.610.870.720.340.420.260.031.040.861.861.791.620.952.312.130.871.571.600.310.030.980.431.761.640.841.35
5-aminovaleric acidME2416640.930.990.911.060.501.160.020.312.411.391.012.160.301.080.811.110.060.700.830.330.012.971.510.100.560.86
glutamic acidME2416010.840.931.180.961.171.440.170.270.740.550.870.700.802.051.051.600.670.741.650.080.103.200.570.441.330.63
aminomalonateME2416531.800.660.760.620.721.410.360.610.160.441.670.332.230.460.642.040.330.820.270.400.630.370.701.681.630.55
fucoseME2416111.351.251.030.881.340.760.390.390.511.231.950.512.120.460.270.580.360.750.730.690.330.750.601.882.140.53
prolineME2415051.180.661.000.691.001.970.270.350.150.861.051.551.321.190.981.020.171.040.230.240.450.242.342.071.641.49
4-methyl-5-thiazoleethanolME2416660.620.861.190.891.060.231.050.620.600.841.580.901.831.130.990.140.651.000.900.420.730.902.011.753.191.41
threonineME2414820.900.801.190.901.010.730.750.750.280.861.830.792.461.320.671.360.740.640.310.630.760.372.431.933.001.01
xylonic acid isomerME2414590.740.990.701.331.410.250.830.900.960.940.460.151.031.283.141.521.181.561.260.520.781.440.330.961.550.70
urocanic acidME2414641.290.441.760.391.190.620.080.130.111.521.521.650.582.410.271.461.231.211.140.050.150.112.140.150.511.33
alanine-alanineME2416560.880.821.041.051.011.710.730.840.462.341.491.300.981.900.981.140.460.620.211.400.510.942.020.420.961.03
tyrosineME2414711.051.461.110.581.420.530.140.140.241.781.132.091.851.290.660.881.431.030.740.190.130.301.451.051.261.13
serineME2414951.241.161.820.751.360.520.340.510.480.760.981.430.971.180.971.720.881.060.460.240.580.340.940.931.521.12
leucineME2415670.951.351.640.911.100.680.610.640.361.220.723.010.771.361.341.010.791.080.420.280.560.291.190.921.971.34
homoserineME2415850.921.731.221.161.351.170.450.570.751.670.891.720.711.171.011.060.871.180.440.380.430.361.260.771.451.22
phenylalanineME2415140.981.261.280.810.970.800.620.830.471.591.132.700.951.361.381.280.880.910.490.690.520.321.620.661.141.20
alanineME2416571.121.311.481.041.180.960.200.520.561.330.811.990.771.271.371.751.001.060.430.290.280.481.030.781.181.09
isoleucineME2415761.031.521.620.870.940.570.390.530.261.350.821.960.841.341.431.390.681.200.380.360.340.211.370.741.431.41
valineME2414630.991.291.440.781.070.650.460.580.371.390.882.220.871.251.441.190.921.100.380.300.510.311.430.821.691.39
indole-3-acetateME2415800.971.961.670.781.161.430.100.140.381.370.731.330.200.601.351.381.360.800.320.160.111.561.350.350.381.46
methionine sulfoxideME2415471.382.181.260.531.410.700.210.320.301.000.881.210.671.361.031.001.231.220.490.210.120.441.140.330.531.03
4-hydroxybenzoateME2416700.802.081.371.651.232.100.150.250.762.101.351.690.450.851.161.561.300.400.230.270.110.641.620.821.071.53
methionineME2415480.681.771.710.901.321.880.360.400.671.590.721.380.601.591.731.121.221.180.630.370.220.520.900.321.241.55
N-acetyl-D-galactosamineME2415421.361.381.631.471.211.560.090.290.251.321.100.490.670.930.273.110.641.140.230.340.110.570.370.790.261.01
riboseME2414971.081.641.662.430.950.810.580.530.671.281.410.240.860.500.231.901.451.280.250.880.490.640.990.380.340.88
2-ketoisocaproic acidME2416891.111.101.051.290.730.370.460.480.302.080.690.520.610.790.891.890.671.670.550.440.530.520.560.670.741.44
lysineME2415621.361.061.330.691.390.570.260.310.311.720.760.731.140.640.780.971.091.850.100.250.290.500.530.320.590.85
nicotinic acidME2415361.031.381.691.820.791.750.380.500.761.131.280.790.881.531.011.820.370.730.470.390.360.941.410.691.261.04
citrullineME2416281.221.601.390.790.881.090.310.320.571.140.561.110.550.760.941.780.951.560.340.140.320.960.450.300.831.08
thymineME2414800.921.631.411.560.341.270.320.330.550.860.720.700.600.770.611.590.811.610.720.540.311.240.740.890.851.37
hypoxanthineME2415811.072.471.231.050.262.040.450.150.791.061.200.770.651.250.501.110.661.500.160.540.360.540.840.501.431.23
uracilME2414681.062.661.670.820.480.970.160.140.290.890.840.710.571.880.621.650.711.400.260.370.041.140.810.661.071.05
threitolME2414840.820.801.151.842.071.230.450.260.840.580.870.291.932.240.280.761.830.651.680.690.511.050.332.932.060.84
ethanolamineME2416141.141.121.532.672.431.120.500.790.490.590.551.290.651.190.861.141.320.970.380.520.780.470.681.961.720.54
glycineME2415941.241.411.200.791.651.520.280.460.180.450.940.771.571.590.811.191.520.780.700.330.460.430.691.491.631.08
cytosinME2416230.930.451.012.402.161.180.900.130.460.871.220.401.611.460.431.482.200.330.460.800.300.740.471.572.471.47
guanineME2415910.911.042.031.591.531.520.900.400.350.991.501.141.071.480.761.602.390.720.140.990.720.181.041.452.540.78
vanillic acidME2414620.992.011.262.201.352.250.310.451.281.241.410.240.741.860.611.101.490.461.770.540.221.070.641.970.180.58
2-deoxytetronic acidME2416940.820.971.971.661.131.180.670.240.760.981.510.611.442.580.690.711.040.391.260.540.550.641.931.421.721.33
benzoic acidME2416471.191.370.861.161.000.620.640.611.230.720.750.490.672.180.420.790.581.211.510.631.250.850.641.301.140.98
fumaric acidME2416100.901.231.391.710.781.010.590.531.170.730.861.490.412.730.390.840.910.781.400.940.571.250.600.751.301.40
pantothenic acidME2415200.840.971.911.101.371.540.380.381.101.120.830.740.510.951.632.301.110.550.840.400.091.043.320.750.891.30
shikimic acidME2414941.001.161.571.881.321.480.680.720.760.850.920.481.100.770.811.041.870.842.490.180.640.802.211.281.070.54
tocopherol alpha-ME2414750.741.180.691.400.961.370.490.571.081.170.860.511.001.231.570.891.111.062.870.830.591.092.621.230.800.95
oxoprolineME2415240.970.550.611.120.840.751.011.002.500.301.280.561.192.270.340.350.780.281.300.741.263.150.380.571.080.57
diglycerolME2416190.740.680.930.830.831.501.230.551.190.421.050.551.161.430.610.671.351.400.630.650.751.781.051.651.910.89
asparagineME2416500.801.270.791.321.011.821.040.671.110.520.941.871.300.870.580.370.600.910.960.490.461.790.760.891.691.14
asparagine dehydratedME2416490.710.870.691.381.112.421.340.831.470.451.030.861.371.080.720.240.600.501.290.590.582.460.900.951.721.02
3,6-anhydro-D-galactoseME2416791.140.790.850.790.931.880.890.841.281.071.010.671.121.020.550.850.540.592.240.860.841.321.360.680.910.94
trans-4-hydroxyprolineME2414741.230.730.790.730.911.970.700.481.650.430.700.340.911.160.781.130.340.480.980.580.861.771.630.880.781.32
glucose-1-phosphateME2416020.810.360.741.170.871.001.351.050.800.501.300.141.311.040.350.461.090.471.641.071.272.010.520.770.571.83
cysteineME2416250.710.540.550.850.891.301.491.312.180.761.250.771.790.800.430.350.330.470.860.891.342.040.991.051.651.23
2,5-dihydroxypyrazine NISTME2416980.790.610.800.670.651.331.461.041.820.620.770.550.871.330.320.550.760.891.030.711.182.400.750.951.041.23
maleimideME2415591.150.580.650.760.761.220.970.811.590.640.880.371.280.840.300.600.440.951.240.660.852.060.500.760.841.03
cerotinic acidME2416350.461.081.711.351.290.731.782.121.200.461.270.570.960.690.390.531.230.931.691.762.361.181.121.300.800.85
lignoceric acidME2415650.471.111.300.891.470.871.522.300.980.631.270.601.190.780.550.361.381.231.811.511.150.831.061.980.680.96
arachidic acidME2416520.680.970.890.810.980.831.141.970.860.701.120.491.041.000.730.890.961.112.131.130.901.231.041.930.601.05
behenic acidME2416480.651.391.250.911.170.880.931.821.040.841.161.231.001.080.421.251.171.232.101.340.570.660.971.760.620.91
hydroxylamineME2415820.790.851.341.441.120.301.220.721.090.660.860.730.841.150.291.101.460.693.250.511.311.321.331.371.091.22
acetophenone NISTME2416610.730.600.670.890.600.401.211.231.091.020.851.011.740.420.650.850.481.191.591.401.091.200.860.871.441.52
capric acidME2416381.181.000.531.090.680.941.010.771.110.860.960.800.910.610.770.600.850.992.340.821.611.080.981.560.940.86
caprylic acidME2416371.130.611.141.081.150.390.910.941.460.620.780.780.970.820.360.600.470.992.251.151.291.181.021.271.360.86
pelargonic acidME2415181.170.560.921.380.690.531.220.871.150.711.170.831.250.760.420.870.100.762.340.891.221.250.811.741.140.92
1-monostearinME2417011.281.030.761.061.120.361.361.460.590.481.211.140.860.501.641.000.781.340.770.590.480.710.850.820.550.83
glycerolME2415971.491.641.010.901.080.640.401.870.380.640.920.920.611.400.861.130.661.100.570.421.230.430.810.691.080.57
linolenic acidME2415630.631.431.040.421.000.961.371.721.160.160.360.550.760.331.810.920.122.281.960.651.090.661.221.280.951.07
nonadecanoic acidME2415340.971.120.991.000.751.031.071.431.380.540.990.460.890.880.571.060.511.480.740.520.291.120.811.380.971.06
cis-gondoic acidME2416311.010.560.350.560.740.950.481.230.520.400.860.170.660.781.690.350.572.151.760.740.551.051.241.310.461.23
oleic acidME2415271.030.960.720.550.720.860.841.120.540.590.820.490.580.581.790.880.902.211.410.610.600.700.920.940.461.09
stearic acidME2414890.770.810.690.670.780.871.071.430.880.720.940.450.930.790.950.690.811.501.280.800.861.331.191.910.601.24
heptadecanoic acidME2415890.881.430.860.660.520.830.961.400.770.510.710.360.590.730.771.000.801.901.930.580.651.130.831.320.481.12
palmitic acidME2415220.870.710.510.460.600.751.361.650.900.540.780.330.710.660.870.680.681.831.810.680.761.271.051.260.511.29
tocopherol acetateME2414790.851.100.730.980.690.940.860.511.081.851.501.480.830.790.260.300.521.400.330.830.721.110.161.380.761.46
hexadecylglycerol NISTME2415880.810.830.850.820.921.110.130.940.990.540.980.730.780.561.120.920.981.800.591.120.501.911.000.700.660.97
adipic acidME2416580.761.170.780.851.011.280.510.400.981.140.711.120.610.851.090.531.211.440.930.530.871.161.461.091.191.53
indole-3-lactateME2415790.551.410.910.990.811.550.330.130.911.611.130.721.040.581.061.111.171.680.670.470.440.982.010.801.001.55
cholesterolME2416330.880.880.840.740.680.930.520.650.811.350.870.900.640.950.780.640.561.361.560.540.441.351.350.580.431.71
glycolic acidME2415931.330.821.041.180.790.900.430.430.771.270.931.190.850.480.621.360.270.771.110.730.101.270.690.570.441.45
N-acetylornithineME2415381.120.830.640.540.660.680.150.160.520.991.250.341.930.420.540.870.241.310.740.210.091.012.240.360.581.93
1-monopalmitinME2417021.481.420.330.530.501.260.470.720.231.001.480.690.911.692.460.520.160.850.930.620.750.461.810.440.811.11
monomyristinME2415461.571.710.450.230.411.480.380.480.500.761.800.910.661.750.630.280.251.451.410.270.450.511.440.480.500.79
1-monooleinME2417031.941.840.370.290.240.510.290.650.331.211.010.890.440.171.320.150.391.480.940.340.440.890.910.350.480.49
2-monooleinME2416872.290.980.370.590.371.110.790.791.480.720.510.340.320.370.660.410.621.181.780.450.800.660.800.330.240.28
malonic acidME2415570.542.401.141.931.461.690.540.510.851.110.770.790.520.650.950.940.391.252.320.690.561.421.260.930.501.08
uridineME2414650.602.261.011.710.471.820.550.560.661.090.332.160.630.450.410.400.271.392.300.891.682.160.410.610.500.85
phenylacetic acidME2415150.740.980.450.940.512.480.200.020.780.960.360.940.070.081.441.190.102.421.680.060.011.760.280.020.061.95
2-monopalmitinME2416861.480.900.721.110.670.870.380.520.790.450.520.160.790.491.180.720.540.992.890.900.401.851.021.060.250.70
chenodeoxycholic acidME2416340.550.340.291.540.620.960.170.191.100.180.520.220.550.410.870.300.612.882.150.600.282.031.040.640.551.72
beta-sitosterolME2416420.700.971.060.060.791.370.910.931.361.800.851.051.390.010.231.241.590.720.151.450.981.680.021.750.021.63
6-deoxyglucoseME2416631.440.500.860.601.070.370.800.450.140.330.730.201.390.800.650.781.460.540.740.560.732.872.330.701.080.27
3-hydroxybutyric acidME2416762.290.320.540.970.490.491.130.390.271.420.930.340.260.550.341.250.170.240.101.031.500.752.020.881.020.77
1,2-anhydro-myo-inositol NISTME2417081.640.830.921.521.620.981.391.661.040.690.500.080.940.610.250.981.200.470.051.841.810.860.320.380.350.60
sarcosineME2414961.690.350.561.181.050.780.170.721.200.560.600.261.950.290.411.800.470.830.331.431.971.120.970.870.610.49
squaleneME2414900.711.820.500.420.462.180.300.471.151.590.930.810.281.011.230.480.341.735.430.370.210.902.620.450.160.94
tocopherol delta-ME2414780.751.230.550.730.421.360.350.420.971.250.730.560.501.011.380.460.591.394.540.200.221.392.220.570.341.52
tocopherol beta-ME2414760.811.200.470.820.741.080.440.361.091.290.880.780.760.331.350.600.771.793.150.400.601.261.810.610.411.09
tocopherol gamma-ME2414770.731.500.270.540.401.700.310.261.401.590.840.800.291.411.130.340.351.533.100.310.231.541.910.310.201.57
6-hydroxynicotinic acidME2416620.834.251.090.660.700.670.110.140.501.900.531.010.250.192.850.731.090.621.600.170.150.881.970.350.441.61
glutaric acidME2415990.871.301.230.841.381.110.290.120.491.420.561.070.350.524.070.921.221.182.580.270.330.802.840.350.351.08

Factors:

F1Group:NA | Timepoint:NA | Gender:NA | Age at start of study (years):-
F2Group:Placebo | Timepoint:Baseline (days 5-7) | Gender:Female spayed | Age at start of study (years):10
F3Group:Placebo | Timepoint:Baseline (days 5-7) | Gender:Female spayed | Age at start of study (years):5
F4Group:Placebo | Timepoint:Baseline (days 5-7) | Gender:Female spayed | Age at start of study (years):7
F5Group:Placebo | Timepoint:Baseline (days 5-7) | Gender:Male castrated | Age at start of study (years):7
F6Group:Placebo | Timepoint:Baseline (days 5-7) | Gender:Male castrated | Age at start of study (years):9
F7Group:Placebo | Timepoint:Completion of treatment (days 26-28) | Gender:Female spayed | Age at start of study (years):5
F8Group:Placebo | Timepoint:Completion of treatment (days 26-28) | Gender:Male castrated | Age at start of study (years):7
F9Group:Placebo | Timepoint:Completion of treatment (days 26-28) | Gender:Male castrated | Age at start of study (years):9
F10Group:Placebo | Timepoint:Recovery (days 68-70) | Gender:Female spayed | Age at start of study (years):10
F11Group:Placebo | Timepoint:Recovery (days 68-70) | Gender:Female spayed | Age at start of study (years):5
F12Group:Placebo | Timepoint:Recovery (days 68-70) | Gender:Female spayed | Age at start of study (years):7
F13Group:Placebo | Timepoint:Recovery (days 68-70) | Gender:Male castrated | Age at start of study (years):7
F14Group:Placebo | Timepoint:Recovery (days 68-70) | Gender:Male castrated | Age at start of study (years):9
F15Group:Synbiotic | Timepoint:Baseline (days 5-7) | Gender:Female spayed | Age at start of study (years):10
F16Group:Synbiotic | Timepoint:Baseline (days 5-7) | Gender:Female spayed | Age at start of study (years):5
F17Group:Synbiotic | Timepoint:Baseline (days 5-7) | Gender:Male castrated | Age at start of study (years):7
F18Group:Synbiotic | Timepoint:Baseline (days 5-7) | Gender:Male castrated | Age at start of study (years):9
F19Group:Synbiotic | Timepoint:Completion of treatment (days 26-28) | Gender:Female spayed | Age at start of study (years):10
F20Group:Synbiotic | Timepoint:Completion of treatment (days 26-28) | Gender:Female spayed | Age at start of study (years):5
F21Group:Synbiotic | Timepoint:Completion of treatment (days 26-28) | Gender:Male castrated | Age at start of study (years):7
F22Group:Synbiotic | Timepoint:Completion of treatment (days 26-28) | Gender:Male castrated | Age at start of study (years):9
F23Group:Synbiotic | Timepoint:Recovery (days 68-70) | Gender:Female spayed | Age at start of study (years):10
F24Group:Synbiotic | Timepoint:Recovery (days 68-70) | Gender:Female spayed | Age at start of study (years):5
F25Group:Synbiotic | Timepoint:Recovery (days 68-70) | Gender:Male castrated | Age at start of study (years):7
F26Group:Synbiotic | Timepoint:Recovery (days 68-70) | Gender:Male castrated | Age at start of study (years):9
Data matrix
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