Clustering data with hclust algorithm for TCA Concentrations in Neuromyelitis Optica Patients (part - II) (Study ST001036)
GC POSITIVE ION MODE (Analysis AN001697)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ketoglutarate | ME250979 | 1.68 | 0.11 | 0.11 | 3.85 | 0.09 | 0.11 | 0.28 | 0.22 | 0.27 | 0.28 | 0.73 | 2.87 | 0.60 | 2.76 | 0.57 | 3.05 | 1.17 |
| Glutamate | ME250983 | 2.04 | 1.48 | 0.16 | 0.20 | 0.25 | 0.22 | 0.05 | 0.02 | 0.03 | 0.04 | 1.28 | 3.80 | 0.73 | 3.33 | 1.18 | 4.33 | 0.10 |
| Aspartate | ME250981 | 0.25 | 0.21 | 0.31 | 0.31 | 0.15 | 0.26 | 0.32 | 0.19 | 0.78 | 0.15 | 0.67 | 4.08 | 0.44 | 2.87 | 1.07 | 4.44 | 0.13 |
| Malate | ME250980 | 0.13 | 0.22 | 0.22 | 0.12 | 0.11 | 0.25 | 0.32 | 0.36 | 0.29 | 0.35 | 0.80 | 3.14 | 0.72 | 3.87 | 0.80 | 3.22 | 0.80 |
| Citrate | ME250986 | NA | 0.02 | 0.03 | NA | 0.03 | 0.01 | 0.18 | 0.20 | 0.15 | 0.16 | 0.07 | 0.43 | 0.07 | 0.47 | 0.07 | 0.40 | 6.08 |
| Lactate | ME250975 | 0.04 | 0.00 | 0.01 | 0.04 | 0.02 | 0.02 | 0.21 | 0.11 | 0.23 | 0.16 | 0.01 | 0.03 | 0.01 | 0.04 | 0.01 | 0.05 | 7.53 |
| Glutamine | ME250984 | 0.45 | 0.44 | 0.41 | 0.44 | 3.47 | NA | 0.46 | 0.44 | 0.51 | 3.69 | NA | 0.16 | NA | 0.16 | 0.00 | 0.19 | 0.26 |
| cis-Aconitic Acid | ME250985 | 1.02 | 0.33 | 0.42 | 0.87 | 0.61 | 0.22 | 0.73 | 0.59 | 2.33 | 1.12 | 0.40 | 0.18 | 0.75 | 0.29 | 0.58 | 0.21 | 2.95 |
| 2-Hydroxyglutarate | ME250982 | NA | 1.88 | 1.95 | NA | 1.91 | 2.03 | 1.81 | 1.80 | NA | 1.80 | 0.01 | 0.19 | 0.01 | 0.21 | 0.01 | 0.20 | 2.04 |
| Fumarate | ME250977 | 0.15 | 0.77 | 0.62 | 0.22 | 0.42 | 0.61 | 0.57 | 1.33 | 0.40 | 1.34 | 0.20 | 1.69 | 0.18 | 2.46 | 0.21 | 1.93 | 1.46 |
| Isocitrate | ME250987 | NA | 0.42 | 0.84 | NA | 0.84 | NA | 0.56 | 0.84 | NA | 0.70 | NA | 0.79 | NA | 0.88 | NA | 0.78 | 2.31 |
| Succinate | ME250976 | 0.58 | 1.25 | 1.25 | 0.58 | 0.95 | 1.39 | 1.25 | 1.20 | 0.85 | 1.38 | 0.10 | 1.02 | 0.07 | 0.85 | 0.09 | 0.93 | 1.60 |
Factors:
| F1 | Time Point:0h | Matrix:Fresh Media | Condition:BGP 50uMGt Gn |
| F2 | Time Point:0h | Matrix:Fresh Media | Condition:BGP50uMGt Gn |
| F3 | Time Point:0h | Matrix:Fresh Media | Condition:BGPGt 0.5 mM Gn |
| F4 | Time Point:0h | Matrix:Fresh Media | Condition:BGPGt 0.5mM Gn |
| F5 | Time Point:0h | Matrix:Fresh Media | Condition:BGPGt 5mM Gn |
| F6 | Time Point:0h | Matrix:Fresh Media | Condition:E Med |
| F7 | Time Point:1h nonCO2 | Matrix:Spent Sup | Condition:BGP50uMGt Gn |
| F8 | Time Point:1h nonCO2 | Matrix:Spent Sup | Condition:BGPGt 0.5 mM Gn |
| F9 | Time Point:1h nonCO2 | Matrix:Spent Sup | Condition:BGPGt 0.5mM Gn |
| F10 | Time Point:1h nonCO2 | Matrix:Spent Sup | Condition:BGPGt 5mM Gn |
| F11 | Time Point:23h +1h nonCO2 | Matrix:pellet | Condition:BGP50uMGt Gn |
| F12 | Time Point:23h + 1h nonCO2 | Matrix:Pellet | Condition:BGP50uMGt Gn |
| F13 | Time Point:23h +1h nonCO2 | Matrix:pellet | Condition:BGPGt 0.5mM Gn |
| F14 | Time Point:23h + 1h nonCO2 | Matrix:Pellet | Condition:BGPGt 0.5 mM Gn |
| F15 | Time Point:23h +1h nonCO2 | Matrix:pellet | Condition:BGPGt 5mM Gn |
| F16 | Time Point:23h + 1h nonCO2 | Matrix:Pellet | Condition:BGPGt 5mM Gn |
| F17 | Time Point:23h | Matrix:Spent Sup | Condition:E Med |
