Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for P4HA1 knockdown in the breast cell line MDA231 Gln metabolism (part II) (Study ST001050)

Targeted GC POSITIVE ION MODE (Analysis AN001865)

Metabolite	Structure	F1	F2	F3	F4
a-ketoglutarate-13C1_15N0	ME271508	3.83	1.58	0.55	0.32
a-glycerol-3P_#2-13C1_15N0	ME271503	NA	NA	0.66	1.68
aOHglutarate-13C4_15N0	ME271518	NA	2.21	1.10	0.30
Arg-13C1_15N0	ME271270	NA	NA	0.87	1.13
a-ketoglutarate-13C2_15N0	ME271509	2.09	0.66	0.78	0.97
aOHglutarate-ALL	ME271520	0.74	0.98	1.12	0.97
Arg-13C2_15N0	ME271271	1.24	1.81	NA	0.47
a-glycerol-3P_#1-13C2_15N0	ME271499	2.11	NA	0.36	0.53
a-glycerol-3P_#1-13C3_15N0	ME271500	NA	NA	0.30	1.35
a-ketoglutarate-13C0_15N0	ME271507	3.34	4.10	0.09	0.10
aOHglutarate-13C2_15N0	ME271516	NA	0.48	1.17	NA
Arg-13C0_15N0	ME271269	1.04	1.24	0.97	0.93
a-glycerol-3P_#2-13C2_15N0	ME271504	NA	1.34	0.83	NA
Asn-13C6_15N0	ME271282	0.90	NA	1.01	1.02
Ala-13C0_15N0	ME271263	1.60	1.59	0.82	0.79
aOHglutarate-13C0_15N0	ME271514	0.95	1.01	1.10	0.92
a-glycerol-3P_#2-13C3_15N0	ME271505	NA	0.20	NA	1.40
Asn-13C1_15N0	ME271278	1.20	0.76	1.11	0.85
Ala-13C2_15N0	ME271265	NA	1.23	1.10	0.73
Arg-13C3_15N0	ME271272	NA	0.08	1.14	1.26
a-glycerol-3P_#1-13C0_15N0	ME271497	0.17	0.33	2.02	0.48
Asn-13C0_15N0	ME271277	2.63	3.04	0.25	0.52
Ala-13C1_15N0	ME271264	0.30	0.29	1.29	1.18
Arg-13C4_15N0	ME271273	1.73	0.05	0.74	1.37
aOHglutarate-13C5_15N0	ME271519	0.25	NA	1.00	1.25
a-glycerol-3P_#2-ALL	ME271506	0.17	0.11	0.12	3.18
aOHglutarate-13C1_15N0	ME271515	NA	1.90	0.76	0.94
a-glycerol-3P_#2-13C0_15N0	ME271502	0.18	0.07	0.09	3.23
Asn-ALL	ME271283	1.85	2.20	0.73	0.59
a-ketoglutarate-13C4_15N0	ME271511	0.55	0.57	1.73	0.56
Asp-13C1_15N0	ME271285	0.06	0.35	1.29	1.25
Ala-13C4_15N0	ME271267	1.71	0.43	1.15	0.41
aOHglutarate-13C3_15N0	ME271517	0.05	NA	1.21	1.11
Asn-13C3_15N0	ME271280	0.53	NA	1.42	0.21
Asn-13C4_15N0	ME271281	0.35	2.07	0.46	1.22
a-glycerol-3P_#1-ALL	ME271501	0.45	0.29	1.84	0.58
Ala-13C3_15N0	ME271266	NA	NA	0.67	1.33
Arg-13C5_15N0	ME271274	1.46	1.09	1.00	0.81
Asp-13C4_15N0	ME271288	NA	NA	1.03	0.97
Ala-ALL	ME271268	1.29	1.31	0.93	0.88
Asp-13C3_15N0	ME271287	0.34	0.05	1.36	1.17
a-glycerol-3P_#1-13C1_15N0	ME271498	0.48	NA	0.76	2.00
Asp-13C0_15N0	ME271284	2.31	2.22	0.61	0.55
a-ketoglutarate-13C3_15N0	ME271510	1.74	1.37	NA	0.63
ASn-13C5_15N0	ME271262	0.44	NA	0.88	1.46
Arg-13C6_15N0	ME271275	NA	0.87	1.11	0.91
a-ketoglutarate-ALL	ME271513	3.06	3.41	0.26	0.25
Asp-13C2_15N0	ME271286	0.09	0.05	1.32	1.30
Asn-13C2_15N0	ME271279	NA	2.02	0.68	0.94
a-ketoglutarate-13C5_15N0	ME271512	NA	0.16	0.96	1.32
Arg-ALL	ME271276	1.05	1.24	0.95	0.96

Factors:

F1	protocol.id:12C14NGln_shCTL
F2	protocol.id:12C14NGln_shP4HA1
F3	protocol.id:13C15NGln_shCTL
F4	protocol.id:13C15NGln_shP4HA1

Data matrix