Clustering data with hclust algorithm for Aspirin Metabolomics in Colorectal Cancer Chemoprevention (part 1 - Colon) (Study ST001091)
HILIC POSITIVE ION MODE (Analysis AN001776)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 |
|---|---|---|---|---|---|---|
| Indoleacetic acid | ME263959 | 0.37 | 0.28 | 5.15 | 0.62 | 0.30 |
| 5-Aminolevulinic acid | ME263943 | 0.64 | 0.55 | 3.35 | 1.33 | 0.60 |
| Creatinine | ME263937 | 0.39 | 0.37 | 4.25 | 1.83 | 0.40 |
| Dodecanoylcarnitine | ME263972 | 0.59 | 0.62 | 1.12 | 2.75 | 0.64 |
| Ornithine | ME263945 | 1.05 | 0.67 | 0.71 | 2.13 | 0.67 |
| Tryptophan | ME263963 | 0.91 | 0.92 | 0.33 | 2.12 | 0.92 |
| Phosphocreatine | ME263965 | 0.36 | 0.30 | 3.02 | 0.05 | 0.37 |
| Arabitol | ME263952 | 0.88 | 0.77 | 2.49 | 0.40 | 0.80 |
| Hypotaurine | ME263936 | 0.96 | 0.95 | 1.99 | 0.28 | 0.97 |
| Benzylamine | ME263935 | 1.06 | 1.02 | 1.93 | 0.37 | 0.61 |
| Phenylethylamine | ME263940 | 1.13 | 1.05 | 2.12 | 0.27 | 0.49 |
| Kynurenic acid | ME263962 | 2.37 | 1.65 | 0.60 | 0.41 | 0.84 |
| Ergocalciferol | ME263973 | 1.19 | 0.86 | NA | NA | 0.93 |
| Sphinganine | ME263971 | 1.07 | 0.94 | 0.05 | 0.08 | 1.13 |
| Imidazoleacetic acid | ME263942 | 1.10 | 1.17 | 0.24 | 0.15 | 1.04 |
| Xanthine | ME263951 | 1.20 | 1.08 | 0.20 | 0.14 | 1.09 |
| Dethiobiotin | ME263966 | 1.32 | 1.01 | 0.30 | 0.26 | 1.10 |
| Uridine | ME263970 | 1.31 | 1.09 | 0.42 | 0.07 | 1.07 |
| Urocanic acid | ME263947 | 1.42 | 1.04 | 0.60 | 0.14 | 0.91 |
| Histidine | ME263953 | 1.21 | 1.02 | 0.53 | 0.72 | 1.10 |
| Kynurenine | ME263964 | 1.33 | 1.05 | 0.47 | 0.56 | 1.06 |
| Proline | ME263938 | 1.21 | 1.12 | 0.41 | 0.60 | 1.12 |
| Cystine | ME263968 | 1.25 | 1.07 | 0.66 | 0.34 | 1.04 |
| Lysine | ME263949 | 1.22 | 1.10 | 0.52 | 0.38 | 1.09 |
| Anserine | ME263969 | 1.15 | 1.02 | 0.44 | 0.29 | 1.22 |
| Serine | ME263934 | 1.20 | 1.16 | 0.38 | 0.39 | 1.14 |
| Tyrosine | ME263961 | 1.16 | 1.08 | 0.37 | 0.43 | 1.10 |
| N-Acetyl-L-aspartic acid | ME263958 | 1.04 | 1.00 | 1.02 | NA | 0.95 |
| Cholic acid | ME263974 | 1.09 | 0.99 | 0.72 | 0.47 | 1.06 |
| Glutamic acid | ME263950 | 1.13 | 1.05 | 0.99 | 0.26 | 1.06 |
| Glutamine | ME263948 | 1.13 | 1.05 | 0.90 | 0.49 | 1.10 |
| 1-Aminocyclopropanecarboxylic acid | ME263933 | 1.17 | 1.10 | 0.85 | 0.31 | 1.11 |
| Phenylpyruvic acid | ME263956 | 1.14 | 1.03 | 0.88 | 0.37 | 1.07 |
| Cystathionine | ME263967 | 1.06 | 0.81 | 1.52 | 0.32 | 0.85 |
| Malic acid | ME263946 | 1.05 | 0.88 | 1.27 | 0.40 | 1.02 |
| Creatine | ME263944 | 1.07 | 0.98 | 1.43 | 0.21 | 0.99 |
| Taurine | ME263941 | 1.11 | 0.99 | 1.28 | 0.19 | 1.01 |
| Aminoadipic acid | ME263954 | 1.35 | 0.85 | 0.96 | 0.45 | 0.90 |
| Glucosamine | ME263960 | 1.46 | 0.83 | 1.25 | 0.25 | 0.80 |
| Nicotine | ME263955 | 1.12 | 0.82 | 1.54 | 0.99 | 0.87 |
| Indole | ME263939 | 1.12 | 1.02 | 0.40 | 1.18 | 1.04 |
| Uric acid | ME263957 | 0.95 | 1.06 | 0.94 | 1.11 | 0.96 |
Factors:
| F1 | Aspirin Dosage:ASA 325 | Sample.Matrix:Colon Mucosal Tissue |
| F2 | Aspirin Dosage:ASA 81 | Sample.Matrix:Colon Mucosal Tissue |
| F3 | Aspirin Dosage:NA | Sample.Matrix:Colon Mucosal Tissue |
| F4 | Aspirin Dosage:NA | Sample.Matrix:Plasma |
| F5 | Aspirin Dosage:PLACEBO | Sample.Matrix:Colon Mucosal Tissue |
