Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Different dose exposure of OPC-163493 on HepG2 cells (part-I) (Study ST001135)

CE UNSPECIFIED ION MODE/Triple quadrupole (Analysis AN001861)

Metabolite	Structure	F1	F2	F3	F4
IMP	ME270837	0.88	0.84	1.38	0.90
GDP	ME270830	0.82	0.84	1.33	1.01
Succinic acid	ME270858	0.85	0.86	1.33	0.96
Coenzyme A	ME270822	0.90	0.53	1.65	0.93
Oxoglutaric acid	ME270849	0.69	0.58	1.57	1.17
AMP	ME270818	0.73	0.69	1.63	0.95
GMP	ME270835	0.70	0.75	1.64	0.91
3-hydroxy-3-methylglutaryl-CoA	ME270811	0.64	0.76	1.56	1.04
ADP	ME270816	0.73	0.81	1.49	0.97
Cis-Aconitic acid	ME270820	0.81	1.01	0.64	1.45
Phosphoribosyl pyrophosphate	ME270852	1.09	1.18	0.46	1.27
Glucose-1-phosphate	ME270831	1.48	0.64	0.93	0.95
Pyruvic acid	ME270853	0.96	1.20	0.86	0.98
Galactose-1-phosphate	ME270829	1.18	0.85	0.85	1.12
Ribulose-5-phosphate	ME270856	1.22	1.06	0.77	0.96
Malonyl-CoA	ME270841	1.17	0.93	0.84	1.03
6-Phosphogluconic acid	ME270813	1.18	0.99	0.83	1.00
UDP-glucose	ME270859	1.13	1.01	0.83	1.03
ADP-ribose	ME270817	1.19	0.96	0.76	1.10
NADPH	ME270847	1.17	1.04	0.74	1.06
Folic acid	ME270824	1.03	1.09	0.92	0.96
Adenylsuccinic acid	ME270815	1.17	1.02	0.90	0.91
Ribose-1-phosphate	ME270854	1.10	0.96	0.96	0.97
2-hydroxyglutaric acid	ME270807	1.11	0.98	0.92	0.99
XMP	ME270860	1.11	1.01	0.89	0.99
3^,5^ cyclic GMP	ME270810	1.08	0.80	1.14	0.98
Glycerol 3-phosphate	ME270834	0.93	0.95	1.13	0.99
N-acetylglutamic acid	ME270843	0.83	0.95	1.17	1.05
Lactic acid	ME270839	0.88	0.88	1.18	1.06
Sedoheptulose 7-phosphate	ME270857	0.91	0.90	1.11	1.09
Citric acid	ME270821	0.90	0.98	0.95	1.17
Ketoisovaleric acid	ME270838	0.90	0.94	1.04	1.12
3-Phosphoglyceric acid	ME270812	1.08	0.91	0.92	1.09
Phosphoenolpyruvic acid	ME270851	1.06	0.88	0.95	1.11
Fructose-1-phosphate	ME270826	1.03	0.99	0.89	1.09
GTP	ME270836	1.07	0.99	0.88	1.06
2-Phosphoglyceric acid	ME270808	1.03	0.86	1.04	1.07
NADP+	ME270846	0.97	0.97	1.03	1.02
Glucose-6-phosphate	ME270832	0.97	0.97	1.02	1.04
NAD+	ME270844	0.97	0.97	1.02	1.04
Fructose-6-phosphate	ME270827	1.02	0.94	0.98	1.06
3^,5^ cyclic AMP	ME270809	0.99	0.99	0.95	1.07
ATP	ME270819	1.00	0.98	0.97	1.04
Acetyl-CoA	ME270814	0.91	0.99	NA	1.12
Mevalonic acid	ME270842	1.25	0.74	NA	0.89
Fumaric acid	ME270828	1.49	1.41	0.04	1.06
2,3-Diphosphoglyceric acid	ME270806	1.62	1.14	0.17	0.65
Glyceraldehyde-3-phosphate	ME270833	1.49	1.15	0.24	0.74
Phosphocreatine	ME270850	1.23	1.11	0.62	1.04
N-carbamoylaspartic acid	ME270848	1.53	1.21	0.36	0.91
Fructose-1,6-biphosphate	ME270825	1.37	1.15	0.59	0.89
NADH	ME270845	1.47	1.13	0.60	0.80
Xylulose-5-phosphate	ME270861	1.42	1.13	0.61	0.84
Dihydroxyacetone phosphate	ME270823	1.38	1.24	0.45	0.94
Malic acid	ME270840	1.38	1.15	0.47	1.01
Ribose-5-phosphate	ME270855	1.38	1.12	0.53	0.96

Factors:

F1	Treatment:-
F2	Treatment:1
F3	Treatment:10
F4	Treatment:3

Data matrix