Clustering data with hclust algorithm for A comprehensive plasma metabolomics dataset for a cohort of mouse knockouts within the International Mouse Phenotyping Consortium (Study ST001154)
HILIC POSITIVE ION MODE/Orbitrap (Analysis AN001944)Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 | F21 | F22 | F23 | F24 | F25 | F26 | F27 | F28 | F29 | F30 | F31 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypoxanthine | ME280176 | 0.31 | 0.09 | 0.74 | 0.21 | 0.11 | 0.22 | 0.26 | 0.17 | 0.12 | 1.70 | 0.16 | 0.14 | 0.44 | 0.47 | 0.20 | 0.14 | 0.24 | 0.24 | 22.17 | 0.57 | 0.21 | 0.17 | 0.31 | 0.12 | 0.17 | 1.07 | 0.40 | 1.21 | 0.51 | 0.18 | 0.43 |
7-Keto-3a,12-a-dihydroxycholanic acid | ME280024 | 0.15 | 0.09 | 0.17 | 0.12 | NA | 0.17 | 0.18 | 0.14 | 0.15 | 0.15 | 0.44 | 0.19 | 11.51 | 0.17 | 0.16 | 1.86 | 2.52 | 0.07 | 0.15 | 0.17 | 0.14 | 2.38 | 0.09 | 0.18 | 0.56 | 0.20 | 0.04 | 0.18 | 0.09 | 0.27 | 9.59 |
Tauroursodeoxycholic acid | ME280087 | 0.13 | 0.17 | 0.10 | 0.16 | 0.05 | NA | 0.04 | NA | 0.15 | 0.12 | 1.24 | 0.11 | 2.28 | 0.13 | 0.14 | 10.80 | 2.80 | 0.06 | 0.14 | 0.23 | 0.17 | 1.99 | 0.13 | 0.11 | 2.84 | NA | 0.12 | 6.90 | 0.08 | 5.50 | 4.98 |
Taurocholic acid | ME280206 | 0.26 | 0.15 | 0.17 | 0.22 | 0.19 | 0.26 | 0.11 | 0.11 | 0.25 | 0.13 | 2.21 | 0.24 | 3.03 | 0.15 | 0.11 | 2.58 | 3.24 | 0.20 | 0.20 | 0.36 | 0.17 | 2.49 | 0.09 | 0.12 | 3.43 | 0.10 | 0.12 | 4.66 | 0.20 | 2.94 | 6.42 |
Chenodeoxycholic acid | ME280036 | 0.28 | 0.46 | 1.44 | 0.53 | 0.33 | 0.22 | 0.70 | 0.48 | 0.35 | 0.65 | 1.66 | 0.69 | 3.00 | 0.85 | 0.59 | 2.45 | 2.01 | 0.49 | 0.48 | 0.63 | 0.48 | 0.93 | 0.53 | 0.69 | 0.67 | 0.50 | 0.55 | 0.82 | 1.07 | 0.87 | 6.95 |
Cholic acid | ME280037 | 0.20 | 0.35 | 0.40 | 0.18 | 0.21 | 0.20 | 0.40 | 0.31 | 0.22 | 0.44 | 1.27 | 0.37 | 2.48 | 0.33 | 0.34 | 4.05 | 1.25 | 0.23 | 0.24 | 0.71 | 0.17 | 1.13 | 0.32 | 0.31 | 0.89 | 0.24 | 0.20 | 0.49 | 0.74 | 0.69 | 11.49 |
Inosine | ME280118 | 1.29 | 0.13 | 1.21 | 0.35 | 0.19 | 0.82 | 0.37 | 0.35 | 0.21 | 0.17 | 0.13 | 0.35 | 0.93 | 0.71 | 0.34 | 0.49 | 0.87 | 0.53 | 9.67 | 0.92 | 0.52 | 0.43 | 0.86 | 0.30 | 0.51 | 4.08 | 0.80 | 1.26 | 1.02 | 0.37 | 0.44 |
Xanthine | ME280099 | NA | 0.29 | 0.47 | NA | NA | NA | 0.26 | NA | 0.18 | 2.04 | NA | NA | 0.56 | 0.29 | 0.19 | NA | 0.17 | 0.20 | 6.06 | 0.75 | 0.16 | 0.17 | 0.25 | NA | 0.14 | 0.70 | 0.24 | 1.15 | 0.34 | 0.24 | 0.92 |
N-Methylleucine | ME280124 | 0.19 | 0.20 | 0.34 | 0.20 | 0.20 | 0.17 | 0.23 | 1.17 | 1.68 | 0.89 | 1.14 | 0.23 | 4.15 | 0.55 | 0.19 | 1.90 | 1.99 | 2.05 | 0.64 | 0.91 | 1.78 | 0.16 | 0.47 | 0.22 | 0.17 | 0.17 | 3.47 | 0.23 | 2.00 | 3.66 | 0.17 |
N-Acetylglutamic acid | ME280186 | NA | NA | NA | NA | 3.54 | 0.62 | NA | NA | 0.60 | 0.56 | NA | 0.62 | 0.51 | NA | NA | 0.65 | NA | 0.58 | NA | 1.07 | 0.74 | 1.12 | 0.61 | 4.77 | NA | 0.47 | NA | NA | NA | 0.55 | 0.57 |
Cotinine | ME280157 | 1.14 | 0.66 | 1.53 | 2.44 | 0.66 | 1.70 | 1.04 | 0.53 | 1.02 | 0.21 | 2.27 | 1.30 | 0.13 | 2.03 | 0.09 | 0.46 | 2.36 | 1.38 | 0.93 | 0.09 | 1.26 | 3.34 | 0.22 | 1.22 | 2.32 | 0.05 | 1.77 | 2.68 | 0.41 | 0.05 | 0.84 |
Androstane-3,17-diol | ME280144 | 0.41 | 1.42 | 0.61 | 2.09 | 0.32 | 2.06 | 0.32 | 2.30 | 1.53 | 0.40 | 1.12 | 0.59 | 0.43 | 1.21 | 0.49 | 1.00 | 2.46 | 1.81 | 1.25 | 0.28 | 0.70 | 1.61 | 1.06 | 1.95 | 1.09 | 0.26 | 2.24 | 1.92 | 0.29 | 0.59 | 1.26 |
Adenosine-3-monophosphate | ME280139 | 1.36 | 0.48 | 0.32 | NA | 0.37 | 0.74 | 0.50 | 1.31 | 0.58 | 2.39 | 0.42 | NA | 0.36 | 0.71 | NA | 1.52 | 1.42 | 0.38 | NA | 1.49 | 0.41 | NA | 1.00 | NA | NA | 0.34 | NA | 1.96 | NA | 1.76 | 0.66 |
Glutathione, reduced | ME280169 | 1.49 | 0.79 | 0.40 | 0.57 | 0.81 | 1.00 | 0.94 | 1.07 | 0.68 | 1.56 | 0.85 | 0.67 | 0.80 | 0.62 | 0.54 | 1.36 | 1.03 | 0.51 | 0.31 | 1.62 | 0.43 | 0.40 | 1.82 | 0.51 | 0.57 | 0.82 | 0.52 | 1.72 | 0.40 | 1.96 | 0.79 |
Arg-Gln | ME280028 | 0.74 | 0.91 | NA | 1.07 | 0.87 | NA | 0.95 | NA | NA | NA | 0.94 | NA | NA | NA | 0.99 | NA | 0.98 | 0.86 | 1.42 | 1.03 | NA | 0.79 | 0.99 | 0.95 | 0.98 | 1.08 | NA | 0.93 | NA | NA | NA |
Arg-Tyr | ME280033 | NA | 0.74 | NA | 1.14 | 0.78 | 0.71 | 1.09 | NA | NA | 0.98 | NA | 0.86 | NA | NA | 1.19 | NA | 1.26 | 1.09 | 1.36 | 0.93 | 0.96 | 1.03 | 0.76 | 1.10 | 0.77 | 0.85 | 0.90 | 0.91 | NA | 0.89 | 0.97 |
Tyr-Arg | ME280094 | NA | 0.74 | NA | 1.14 | 0.78 | 0.71 | 1.09 | NA | NA | 0.98 | NA | 0.86 | NA | NA | 1.19 | NA | 1.26 | 1.09 | 1.36 | 0.93 | 0.96 | 1.03 | 0.76 | 1.10 | 0.77 | 0.85 | 0.90 | 0.91 | NA | 0.89 | 0.97 |
Pipecolic acid | ME280196 | 1.23 | 1.71 | 0.80 | 0.74 | 1.46 | 0.80 | 2.90 | 2.51 | 0.59 | 0.54 | 0.61 | 0.77 | 0.75 | 0.72 | 1.19 | 1.47 | 0.63 | 0.61 | 1.12 | 0.83 | 0.65 | 0.85 | 0.60 | 0.69 | 1.19 | 1.37 | 1.67 | 0.65 | 0.59 | 0.60 | 1.10 |
Thr-Asn | ME280090 | 0.85 | 0.96 | 1.08 | 1.30 | 0.83 | 0.99 | 0.90 | 1.32 | 0.86 | 1.00 | NA | NA | NA | 0.92 | NA | NA | 1.23 | NA | 0.88 | 0.95 | 1.09 | NA | 1.05 | 1.08 | NA | 0.75 | 1.08 | NA | 1.51 | 0.95 | 0.90 |
Guanosine | ME280172 | 1.41 | 0.26 | 2.17 | 0.51 | 0.37 | 0.92 | 0.68 | 0.51 | 0.32 | 0.86 | 0.24 | 0.87 | 1.77 | 1.27 | 0.40 | 0.69 | 1.01 | 0.65 | 1.57 | 1.25 | 0.22 | 0.69 | 1.36 | 0.51 | 0.70 | 1.51 | 1.49 | 1.23 | 2.98 | 0.67 | 0.38 |
5-Hydroxytryptophol | ME280022 | 1.12 | 1.09 | 2.21 | 0.46 | 0.94 | 0.75 | 1.05 | 0.68 | 0.25 | 1.02 | 0.50 | 0.80 | 0.81 | 1.21 | 0.71 | 0.30 | 0.82 | 0.59 | 1.76 | 1.43 | 0.31 | 0.39 | 1.25 | 0.67 | 0.55 | 1.30 | 1.01 | 0.86 | 2.22 | 0.48 | 1.00 |
N-Acetyl-5-hydroxytryptamine | ME280120 | 0.90 | 1.08 | 1.66 | 1.07 | 1.03 | 0.93 | 0.67 | 0.41 | 0.53 | 1.43 | 0.54 | 0.60 | 0.58 | 0.69 | 1.10 | 0.37 | 0.82 | 0.71 | 1.99 | 1.31 | 0.61 | 0.69 | 1.40 | 0.90 | 1.00 | 1.05 | 0.97 | 0.71 | 1.89 | 0.79 | 0.39 |
S-Adenosyl-methionine | ME280202 | 0.76 | 0.89 | 0.76 | 0.87 | 1.00 | NA | 0.92 | NA | 1.23 | 0.86 | 0.91 | NA | 0.89 | 1.00 | 0.76 | 0.77 | 0.73 | 0.90 | 0.88 | 1.11 | NA | 1.00 | 1.63 | 1.02 | NA | 0.89 | 0.97 | 1.04 | 0.88 | 0.94 | 0.91 |
Ser-Lys | ME280080 | 0.84 | NA | 1.05 | 1.04 | NA | NA | 1.26 | NA | 0.96 | 0.88 | 0.88 | NA | 0.96 | 1.10 | 1.00 | NA | 0.94 | NA | 0.92 | 0.96 | 1.09 | 0.89 | 1.02 | 0.87 | NA | 0.90 | 1.10 | 1.28 | NA | 1.38 | 0.71 |
N-Acetyl-L-glutamine | ME280067 | 1.17 | 0.66 | 1.17 | 0.83 | 0.83 | 1.35 | 0.71 | 1.17 | 0.82 | 0.87 | 0.69 | 0.80 | 0.91 | 0.77 | 1.70 | 0.79 | 0.46 | 0.66 | 0.79 | 0.94 | 0.79 | 1.06 | 0.94 | 0.87 | 0.93 | 0.90 | 1.25 | 1.13 | 3.23 | 1.07 | 1.51 |
Hydrocortisone | ME280050 | 1.62 | 1.35 | 0.40 | 0.60 | 1.17 | 1.56 | 1.41 | 0.43 | 1.22 | 0.53 | 1.14 | 0.47 | 0.99 | 0.49 | 1.27 | 0.84 | 0.99 | 0.26 | 0.86 | 1.18 | 1.17 | 0.53 | 0.58 | 1.22 | 0.50 | 2.10 | 1.32 | 2.00 | 0.76 | 1.57 | 0.66 |
2^-Deoxyguanosine | ME280102 | 0.86 | 0.87 | 1.61 | 0.80 | 0.74 | 0.85 | 0.76 | 0.47 | 0.88 | 0.77 | 0.82 | 1.08 | 0.84 | 1.47 | 1.93 | 1.06 | 0.49 | 0.40 | 0.88 | 0.87 | 1.19 | 0.59 | 1.25 | 0.65 | 1.49 | 0.56 | 0.65 | 2.24 | 1.31 | 0.76 | 2.13 |
Ser-Thr | ME280081 | 0.97 | NA | 1.10 | 1.04 | 0.79 | 0.92 | 1.02 | 1.32 | 0.98 | 0.92 | 1.05 | 0.93 | 0.72 | 0.68 | 0.88 | 0.96 | 1.02 | NA | 1.05 | 1.06 | 0.90 | NA | 1.14 | 0.71 | 1.00 | 0.78 | 0.94 | NA | 1.25 | NA | NA |
Arg-Pro | ME280031 | 0.56 | 1.99 | 0.98 | 0.70 | 0.67 | 0.66 | 0.85 | 0.84 | 1.32 | 0.93 | 1.67 | 0.66 | 1.03 | 1.46 | 0.77 | 0.61 | 1.15 | 1.02 | 2.32 | 1.04 | NA | 1.04 | 1.12 | 0.52 | 0.55 | 0.84 | 0.61 | 0.76 | 1.09 | 1.08 | 0.86 |
Ala-Gln | ME280025 | 0.66 | 0.42 | 0.77 | 1.26 | 1.31 | 1.39 | 1.51 | 1.55 | 0.60 | 1.16 | 0.43 | 0.67 | 0.77 | 0.48 | 1.09 | 0.42 | 0.98 | 1.16 | 0.53 | 1.16 | 1.05 | 1.39 | 0.43 | 1.40 | 0.41 | 0.96 | 1.71 | 1.47 | 1.25 | 0.82 | 0.68 |
Carnosine | ME280154 | 0.76 | 0.93 | NA | 1.21 | NA | NA | 1.06 | 1.13 | 1.01 | NA | 0.94 | 0.89 | 0.84 | 1.11 | 1.28 | 0.92 | 0.90 | 0.94 | 1.45 | 0.97 | 0.98 | 0.88 | 0.94 | 0.94 | 0.84 | 1.15 | 1.16 | 1.25 | 0.91 | 0.91 | 0.78 |
5-Methoxy-3-indoleacetic acid | ME280109 | 1.14 | 1.17 | 0.92 | 0.71 | 0.73 | 0.65 | 0.93 | 0.91 | 0.77 | 1.03 | 1.13 | 1.00 | NA | 1.16 | 1.05 | 0.82 | 0.69 | 0.76 | 0.84 | 0.87 | 1.05 | 2.42 | 1.21 | 0.97 | 1.05 | 0.67 | 1.22 | 0.67 | 0.76 | 1.38 | 0.73 |
Leu-Ala | ME280055 | 1.19 | 0.75 | 1.06 | 1.78 | 0.89 | 1.53 | 1.09 | 0.88 | 1.10 | 0.66 | 1.62 | 0.99 | 0.65 | 1.69 | 0.51 | 0.80 | 1.50 | 0.83 | 0.78 | 0.67 | 1.15 | 1.42 | 0.69 | 1.00 | 1.57 | 0.68 | 1.23 | 1.67 | 0.75 | 0.65 | 1.12 |
(S)-Cotinine N-oxide | ME280016 | 1.37 | 0.97 | 1.45 | 1.78 | 0.98 | 0.96 | 1.23 | 0.66 | 0.81 | 0.62 | 1.52 | 1.12 | 0.49 | 1.14 | 0.54 | 0.54 | 1.59 | 1.18 | 1.16 | 0.71 | 1.03 | 1.83 | 0.57 | 1.12 | 1.16 | 0.55 | 1.17 | 1.30 | 1.22 | 0.50 | 1.35 |
Allantoic acid | ME280143 | 1.27 | NA | 0.96 | 1.13 | 1.05 | 1.00 | 0.93 | NA | 0.94 | 0.88 | 0.88 | 0.78 | 0.78 | 0.77 | 1.14 | 1.01 | 1.02 | 0.83 | 1.01 | 1.07 | 1.19 | 1.01 | 0.76 | 1.09 | 0.92 | 0.66 | 0.96 | 1.08 | 0.99 | 1.39 | NA |
3-Indoleacetic acid | ME280106 | 0.57 | 0.99 | 0.82 | 2.08 | 1.36 | 1.10 | 1.25 | 0.91 | 2.06 | 0.79 | 1.35 | 1.22 | 0.89 | 0.65 | 0.95 | 1.05 | 1.01 | 0.88 | 0.88 | 0.83 | 1.29 | 0.76 | 1.31 | 0.74 | 0.84 | 0.83 | 1.05 | 0.81 | 1.31 | 0.59 | 0.81 |
S-Adenosyl-homocysteine | ME280201 | 0.77 | 1.20 | 1.10 | 1.09 | 1.43 | 0.76 | 1.10 | 0.59 | 0.86 | 1.57 | 1.16 | 0.48 | 0.96 | 0.81 | 0.92 | 0.62 | 1.47 | 1.16 | 1.14 | 0.99 | 0.47 | 1.83 | 0.74 | 0.68 | 0.51 | 0.70 | 1.03 | 1.10 | 1.47 | 0.67 | 1.00 |
Biliverdin | ME280150 | 0.91 | 1.24 | 1.29 | 1.39 | 0.90 | 0.68 | 0.70 | 0.77 | 1.15 | 0.80 | 0.76 | 0.81 | 1.20 | 0.78 | 0.90 | 0.90 | 1.46 | 1.39 | 1.21 | 0.69 | 1.41 | 1.62 | 0.69 | 1.23 | 1.11 | 0.73 | 1.70 | 1.06 | 0.98 | 0.56 | 1.72 |
Histamine | ME280173 | 0.84 | 0.97 | 1.31 | 1.13 | 1.11 | 0.79 | 1.27 | 0.61 | 0.81 | 1.16 | 1.04 | 0.95 | 1.75 | 0.91 | 0.75 | 0.55 | 0.77 | 0.81 | 1.22 | 1.09 | 0.51 | 0.78 | 1.71 | 0.81 | 0.71 | 0.93 | 1.01 | 0.99 | 1.67 | 0.68 | 0.88 |
Stachydrine | ME280085 | 0.88 | 0.66 | 0.56 | 1.24 | 1.63 | 0.80 | 0.60 | 0.80 | 0.78 | 1.07 | 1.07 | 0.63 | 0.89 | 0.62 | 1.01 | 0.99 | 1.43 | 1.15 | 1.04 | 0.92 | 0.95 | 1.46 | 0.55 | 1.19 | 1.20 | 1.42 | 0.82 | 1.60 | 0.92 | 1.04 | 1.56 |
Ecgonine | ME280161 | 0.86 | 1.27 | 0.96 | 0.99 | 0.87 | 0.73 | 1.04 | 0.83 | 1.01 | 1.29 | 1.88 | 0.76 | 1.15 | 0.65 | 1.26 | 1.35 | 0.88 | 1.03 | 1.24 | 0.92 | 1.25 | 0.70 | 0.97 | 0.92 | 0.66 | 0.67 | 0.84 | 1.00 | 1.65 | 0.74 | 1.07 |
Pro-Gln | ME280076 | 1.48 | 1.02 | 0.47 | 0.77 | 1.17 | 1.15 | 1.03 | 1.08 | 1.52 | 1.07 | 1.08 | 1.09 | 0.61 | 0.50 | 1.36 | 1.27 | 1.14 | 1.20 | 0.91 | 0.99 | 1.02 | 1.63 | 0.93 | 0.86 | 0.75 | 0.93 | 0.69 | 0.67 | 0.77 | 0.80 | 1.02 |
Corticosterone | ME280038 | 1.14 | 0.83 | 1.24 | 0.93 | 1.14 | 0.78 | 1.03 | 0.90 | 1.03 | 0.77 | 1.50 | 1.15 | 1.30 | 0.72 | 1.55 | 0.76 | 1.20 | 0.80 | 0.64 | 1.09 | 0.59 | 0.95 | 0.67 | 1.41 | 0.39 | 0.79 | 1.15 | 0.93 | 1.10 | 1.17 | 0.82 |
TMAO | ME280208 | 0.86 | 1.21 | 1.27 | 0.98 | 1.04 | 0.86 | 1.44 | 1.20 | 0.75 | 0.66 | 1.24 | 0.91 | 0.68 | 1.20 | 1.20 | 1.01 | 0.75 | 1.10 | 1.69 | 0.88 | 1.47 | 0.74 | 1.20 | 1.12 | 1.10 | 1.06 | 0.74 | 1.31 | 0.76 | 0.73 | 0.53 |
L-Cysteine-glutathione disulfide | ME280054 | 0.82 | 0.93 | 1.06 | 1.04 | 0.96 | 0.72 | 0.89 | 0.91 | 0.91 | 0.97 | 1.09 | 0.75 | 0.82 | 0.89 | 1.11 | 0.85 | 1.43 | 2.09 | 1.24 | 0.98 | 1.07 | 1.43 | 0.91 | 0.94 | 0.74 | 1.01 | 1.12 | 0.63 | 1.11 | 0.90 | 0.77 |
L-Cysteine S-sulfate | ME280053 | 0.87 | 0.88 | 0.69 | 1.23 | 1.12 | 1.02 | 0.89 | 1.10 | 1.38 | 0.90 | 1.45 | 0.61 | 0.99 | 0.94 | 0.83 | 0.92 | 1.31 | 0.95 | 0.75 | 0.97 | 0.86 | 1.34 | 0.80 | 1.22 | 1.40 | 0.54 | 1.08 | 1.21 | 0.64 | 0.69 | 1.62 |
Arg-Ser | ME280032 | 0.82 | 0.79 | 0.84 | 1.19 | 0.99 | 1.12 | 1.08 | 1.47 | 0.77 | 0.80 | 1.01 | 0.85 | 0.82 | 0.82 | 0.90 | 0.76 | 1.05 | 0.92 | 1.09 | 1.01 | NA | 1.29 | 0.77 | 0.92 | 0.83 | 0.80 | 1.41 | 1.09 | 0.88 | 1.18 | 0.83 |
2-Indolinone | ME280018 | 1.11 | 1.14 | 1.23 | 1.12 | 1.32 | 0.74 | 1.45 | 1.16 | 0.96 | 0.94 | 0.95 | 0.76 | 1.06 | 0.94 | 0.96 | 1.00 | 1.11 | 1.14 | 1.33 | 0.61 | 1.43 | 1.05 | 0.70 | 1.29 | 1.42 | 0.92 | 1.52 | 1.23 | 1.09 | 0.58 | 0.92 |
Retinoic acid | ME280127 | 0.58 | 1.06 | 1.13 | 1.28 | 1.13 | 0.74 | 1.69 | 0.72 | 0.92 | 0.76 | 0.78 | 1.14 | 1.34 | 1.15 | 0.68 | 0.93 | 1.31 | 1.03 | 1.24 | 0.90 | 1.33 | 0.78 | 0.71 | 1.22 | 0.68 | 0.88 | 1.32 | 1.29 | 0.78 | 1.00 | 1.24 |
N-Formylmethionine | ME280070 | 0.64 | 0.88 | 0.62 | 1.46 | 0.97 | 0.66 | 0.84 | 1.55 | 1.32 | 0.76 | 1.09 | 1.14 | 1.07 | 1.25 | 1.31 | 0.99 | 0.69 | 1.16 | 0.77 | 1.01 | 0.91 | 1.08 | 0.67 | 0.89 | 1.42 | 0.68 | 0.91 | 1.16 | 0.80 | 1.34 | 0.98 |
Val-Gln | ME280096 | 1.11 | 1.06 | NA | 1.10 | 0.84 | 1.03 | 0.90 | 1.09 | 0.99 | 0.92 | 1.22 | 1.11 | 0.86 | 0.86 | 0.95 | 0.79 | 0.89 | 1.57 | 1.16 | 1.08 | 1.23 | 0.79 | 0.85 | 1.01 | 0.74 | 0.78 | 1.08 | 0.81 | 1.22 | 0.95 | 0.88 |
Cortisone | ME280112 | 1.41 | 1.16 | 1.02 | 1.03 | 1.23 | 0.69 | 1.18 | 0.76 | 0.72 | 1.40 | 0.93 | 1.26 | 0.73 | 0.87 | 1.18 | 1.10 | 0.77 | 0.73 | 0.84 | 0.89 | 1.58 | 0.92 | 1.23 | 1.26 | 0.79 | 0.87 | 0.98 | 0.64 | 0.83 | 1.21 | 0.92 |
Ala-Ile | ME280110 | 0.52 | 0.79 | 0.87 | 1.01 | 0.86 | 0.78 | 0.88 | 1.09 | 0.97 | 1.27 | 1.16 | 0.97 | 0.88 | 1.27 | 1.15 | 0.78 | 1.40 | 0.49 | 0.97 | 1.25 | 1.08 | 0.77 | 0.82 | 1.09 | 1.20 | 0.60 | 0.82 | 0.71 | 1.25 | 0.67 | 1.05 |
Caffeine | ME280152 | 1.10 | 1.22 | 1.07 | 1.19 | 1.17 | 1.31 | 1.29 | 1.19 | 1.17 | 1.15 | 1.20 | 0.88 | 0.98 | 1.04 | 1.15 | 0.88 | 0.84 | 0.84 | 0.96 | 0.70 | 1.12 | 1.17 | 1.66 | 1.02 | 1.37 | 0.66 | 1.27 | 1.01 | 0.48 | 0.74 | 0.92 |
Cytosine | ME280114 | 1.51 | 1.46 | 0.94 | 1.07 | 0.91 | 1.05 | 1.17 | 1.02 | 0.91 | 0.99 | 0.80 | 1.23 | 1.08 | 1.16 | 1.63 | 1.02 | 0.85 | 1.07 | 1.07 | 0.61 | 1.23 | 0.93 | 0.70 | 0.76 | 1.33 | 0.94 | 1.21 | 1.01 | 1.19 | 1.14 | 1.27 |
Propionylcarnitine | ME280199 | 0.86 | 1.08 | 0.90 | 0.92 | 1.08 | 1.00 | 1.12 | 1.02 | 0.83 | 1.35 | 1.09 | 1.11 | 1.07 | 1.25 | 1.81 | 1.37 | 0.85 | 0.94 | 1.04 | 0.77 | 0.98 | 0.73 | 1.11 | 0.98 | 1.05 | 1.20 | 1.02 | 1.01 | 0.81 | 0.85 | 1.07 |
1_D3-Histamine, N-methyl- iSTD | ME280005 | 1.11 | 1.12 | 1.12 | 0.86 | 1.06 | 0.85 | 1.10 | 0.80 | 1.14 | 1.06 | 1.07 | 1.12 | 1.05 | 0.97 | 1.13 | 1.10 | 0.47 | 0.49 | 1.06 | 1.16 | 1.20 | 0.47 | 1.09 | 0.70 | 0.92 | 1.06 | 0.70 | 0.84 | 1.16 | 1.15 | 1.00 |
3-Hydroxybutyrylcarnitine | ME280019 | 0.85 | 1.42 | 1.42 | 0.98 | 0.97 | 0.87 | 1.15 | 0.96 | 1.17 | 1.56 | 0.88 | 1.05 | 0.86 | 1.11 | 1.02 | 0.88 | 0.78 | 0.80 | 0.90 | 1.08 | 0.93 | 0.48 | 0.99 | 0.89 | 0.64 | 1.05 | 0.98 | 1.03 | 0.93 | 0.73 | 1.18 |
Hexanoyl-L-carnitine | ME280047 | 0.64 | 0.97 | 1.54 | 1.07 | 0.78 | 0.84 | 0.94 | 0.97 | 0.95 | 1.29 | 1.05 | 1.21 | 1.13 | 1.15 | 1.13 | 0.75 | 0.68 | 0.72 | 0.85 | 1.07 | 0.88 | 0.55 | 1.50 | 1.02 | 0.85 | 1.03 | 1.06 | 0.99 | 0.83 | 0.84 | 1.31 |
Stearoyl-L-carnitine | ME280086 | 0.88 | 1.06 | 1.36 | 1.14 | 0.76 | 0.82 | 0.95 | 1.00 | 1.18 | 0.96 | 0.99 | 1.07 | 1.30 | 1.32 | 0.99 | 0.82 | 0.43 | 0.56 | 0.84 | 1.11 | 0.88 | 0.47 | 1.20 | 0.75 | 1.06 | 0.96 | 0.84 | 1.13 | 1.13 | 1.17 | 1.05 |
Lauroyl-L-carnitine | ME280052 | 0.78 | 0.92 | 1.39 | 1.01 | 0.80 | 0.72 | 0.96 | 1.00 | 1.04 | 1.01 | 0.97 | 1.17 | 1.15 | 1.17 | 0.95 | 0.80 | 0.57 | 0.63 | 0.84 | 1.17 | 0.93 | 0.51 | 1.22 | 0.92 | 0.93 | 1.01 | 1.02 | 1.17 | 0.98 | 0.95 | 1.34 |
Linoleoylcarnitine | ME280059 | 0.72 | 0.97 | 1.32 | 1.07 | 0.71 | 0.77 | 0.88 | 0.96 | 0.97 | 0.87 | 1.01 | 0.97 | 1.20 | 1.35 | 0.88 | 0.77 | 0.63 | 0.63 | 0.79 | 1.19 | 0.77 | 0.55 | 1.15 | 0.96 | 1.03 | 1.00 | 0.97 | 1.22 | 1.12 | 1.07 | 1.38 |
Arg-Val | ME280034 | 0.73 | 1.31 | 1.20 | 1.63 | 0.95 | 0.87 | 0.82 | 0.80 | 0.80 | 0.78 | 0.82 | 0.96 | 0.99 | 0.85 | 0.83 | 0.75 | 1.66 | 1.21 | 1.25 | 0.95 | 1.17 | 0.94 | 0.93 | 0.81 | 0.87 | 0.94 | 1.15 | 1.00 | 1.06 | 0.89 | 0.72 |
Nicotinamide riboside cation | ME280072 | 0.86 | 0.94 | 1.14 | 1.23 | 0.75 | 0.87 | 0.91 | 1.16 | 0.93 | 0.74 | 0.88 | 0.67 | 1.31 | 0.95 | 0.87 | 1.01 | 1.07 | 0.81 | 1.13 | 1.06 | 0.80 | 0.90 | 0.88 | 1.33 | 0.80 | 1.33 | 1.18 | 1.59 | 0.95 | 0.73 | 0.88 |
4-Guanidinobutyric acid | ME280133 | 1.23 | 0.92 | 0.56 | 1.15 | 1.45 | 1.13 | 1.18 | 1.07 | 1.03 | 1.26 | 0.98 | 0.81 | 0.77 | 0.53 | 1.18 | 0.98 | 1.19 | 1.22 | 1.21 | 0.84 | 1.25 | 1.16 | 1.11 | 0.95 | 1.25 | 1.05 | 0.98 | 0.89 | 0.63 | 1.01 | 0.94 |
(R)-Butyrylcarnitine | ME280015 | 1.19 | 1.13 | 0.83 | 0.93 | 1.17 | 0.97 | 1.20 | 1.38 | 1.09 | 1.48 | 0.95 | 0.91 | 0.96 | 0.72 | 1.36 | 1.20 | 0.89 | 1.12 | 1.00 | 0.83 | 1.26 | 0.68 | 1.47 | 0.74 | 0.81 | 1.03 | 0.93 | 0.76 | 0.68 | 1.23 | 1.05 |
Gly-Pro | ME280117 | 0.92 | 0.89 | 0.78 | 0.97 | 0.96 | 0.88 | 1.36 | 1.96 | 1.07 | 0.67 | 1.09 | 0.86 | 1.06 | 0.93 | 1.00 | 0.99 | 0.97 | 1.15 | 0.86 | 1.00 | 0.96 | 0.96 | 1.25 | 0.98 | 1.17 | 0.81 | 0.83 | 0.88 | 0.99 | 0.85 | 0.92 |
5^-Methylthioadenosine | ME280134 | 1.27 | 0.89 | 1.58 | 1.23 | 1.29 | 1.06 | 1.23 | 1.05 | 1.01 | 1.25 | 0.92 | 1.30 | 1.31 | 0.82 | 1.24 | 0.68 | 1.01 | 1.09 | 0.98 | 0.70 | 1.26 | 1.09 | 0.89 | 1.20 | 0.79 | 0.65 | 1.23 | 1.22 | 0.86 | 0.71 | 0.88 |
6-Methyladenosine | ME280135 | 0.80 | 1.07 | 1.25 | 1.41 | 1.21 | 0.83 | 1.15 | 0.86 | 1.29 | 1.21 | 0.89 | 0.98 | 1.01 | 0.87 | 1.16 | 0.70 | 1.00 | 1.06 | 1.36 | 0.85 | 1.04 | 0.96 | 1.00 | 1.21 | 0.84 | 0.77 | 1.16 | 1.01 | 1.19 | 0.82 | 0.90 |
Biotin | ME280151 | 1.27 | 1.24 | 1.35 | 1.24 | 1.09 | 0.80 | 0.80 | 1.11 | 0.91 | 1.04 | 0.89 | 1.01 | 0.66 | 1.02 | 0.79 | 0.70 | 0.88 | 1.25 | 0.92 | 1.00 | 1.36 | 0.87 | 0.88 | 1.22 | 0.69 | 0.77 | 1.17 | 0.97 | 1.24 | 0.72 | 1.13 |
1-Methylnicotinamide | ME280128 | 0.91 | 0.77 | 0.92 | 0.82 | 1.03 | 0.84 | 0.91 | 0.79 | 0.88 | 1.24 | 0.89 | 1.27 | 0.98 | 0.90 | 0.78 | 0.65 | 0.95 | 0.98 | 1.42 | 1.28 | 0.91 | 0.94 | 1.22 | 0.97 | 0.71 | 0.82 | 1.22 | 0.98 | 0.80 | 0.79 | 0.80 |
Nicotinamide | ME280189 | 0.94 | 0.77 | 1.04 | 0.86 | 1.04 | 0.83 | 0.89 | 0.74 | 0.72 | 1.22 | 0.89 | 1.03 | 0.97 | 1.02 | 0.76 | 0.59 | 0.90 | 0.89 | 1.22 | 1.41 | 0.81 | 0.97 | 1.03 | 0.92 | 0.77 | 0.94 | 1.06 | 1.08 | 0.84 | 0.70 | 0.81 |
3-Ureidopropionic acid | ME280130 | 0.79 | 1.15 | 0.68 | 1.13 | 1.37 | 0.76 | 0.91 | 1.14 | 0.88 | 0.94 | 1.43 | 0.98 | 1.07 | 1.53 | 1.01 | 0.96 | 0.85 | 1.19 | 1.01 | 0.95 | 1.00 | 1.10 | 0.84 | 0.94 | 0.93 | 0.83 | 0.93 | 0.97 | 0.93 | 1.27 | 0.80 |
N-Methyltyrosine | ME280125 | 1.08 | 0.84 | 0.81 | 0.91 | 1.25 | 1.02 | 1.02 | 0.95 | 0.77 | 1.39 | 1.26 | 1.07 | 0.59 | 0.91 | 0.95 | 0.87 | 0.81 | 1.18 | 1.09 | 0.99 | 1.04 | 1.01 | 1.00 | 0.98 | 1.11 | 0.97 | 0.94 | 0.79 | 1.39 | 1.05 | 0.96 |
N2,N2-Dimethylguanosine | ME280119 | 0.81 | 0.87 | 1.02 | 0.97 | 0.70 | 0.71 | 1.10 | 1.14 | 1.30 | 0.93 | 1.01 | 0.81 | 1.22 | 0.95 | 0.90 | 0.92 | 0.88 | 1.08 | 0.84 | 0.97 | 1.04 | 0.97 | 1.18 | 0.99 | 1.26 | 0.67 | 1.07 | 1.35 | 1.14 | 1.27 | 1.09 |
4-Pyridoxic acid | ME280021 | 1.00 | 0.85 | 1.28 | 0.92 | 1.24 | 1.00 | 1.31 | 1.04 | 0.96 | 0.98 | 1.17 | 1.10 | 1.07 | 1.03 | 0.79 | 0.72 | 0.66 | 0.86 | 1.15 | 1.05 | 0.91 | 0.76 | 0.98 | 1.02 | 1.25 | 0.87 | 1.03 | 0.97 | 1.06 | 0.95 | 0.77 |
3-Hydroxyphenylacetic acid | ME280104 | 0.98 | 0.95 | 0.83 | 1.13 | 1.19 | 0.99 | 0.91 | 0.85 | 0.94 | 1.15 | 0.89 | 0.88 | 1.21 | 0.73 | 1.07 | 1.33 | 0.91 | 0.96 | 0.72 | 0.99 | 1.21 | 0.93 | 0.94 | 1.26 | 0.83 | 1.02 | 1.37 | 0.88 | 0.83 | 1.02 | 1.11 |
Lys-Gly | ME280061 | 1.06 | 0.91 | 0.78 | 0.92 | 1.38 | 1.11 | 0.84 | 0.97 | 1.16 | 1.12 | 1.01 | 0.71 | 0.78 | 0.82 | 1.05 | 1.14 | 0.88 | 1.05 | 1.28 | 1.03 | 1.26 | 0.91 | 0.84 | 1.12 | 0.97 | 0.74 | 1.04 | 0.93 | 0.83 | 1.03 | 1.17 |
N-Acetylglucosamine | ME280122 | 0.88 | 0.92 | 1.16 | 1.39 | 0.92 | 0.88 | 0.85 | 1.22 | 1.15 | 0.67 | 1.18 | 1.06 | 0.87 | 1.28 | 1.25 | 0.88 | 0.91 | 1.04 | 1.20 | 0.89 | 1.24 | 0.99 | 0.96 | 1.10 | 1.13 | 0.81 | 1.24 | 0.99 | 0.93 | 0.71 | 0.93 |
Proline-hydroxyproline | ME280198 | 0.56 | 1.13 | 1.07 | 1.06 | 0.81 | 0.87 | 1.30 | 0.95 | 1.00 | 0.82 | 1.08 | 1.18 | 1.00 | 0.96 | 1.21 | 1.02 | 1.04 | 0.86 | 1.29 | 1.09 | 0.75 | 1.11 | 0.84 | 0.98 | 0.90 | 0.77 | 0.82 | 0.94 | 1.01 | 1.17 | 0.88 |
Ala-Ala | ME280141 | 0.81 | 0.85 | 0.69 | 1.44 | 1.26 | 1.01 | 1.17 | 1.04 | 1.04 | 0.99 | 0.94 | 0.97 | 0.83 | 0.95 | 1.32 | 0.90 | 1.08 | 1.21 | 0.68 | 0.96 | 1.19 | 0.98 | 0.82 | 0.96 | 1.15 | 0.83 | 1.21 | 1.08 | 1.06 | 0.86 | 0.94 |
O-Acetyl-L-homoserine | ME280073 | 0.87 | 1.05 | 0.74 | 1.10 | 0.84 | 0.99 | 0.99 | 1.28 | 0.87 | 0.91 | 0.81 | 0.80 | 0.83 | 0.94 | 0.93 | 0.83 | 1.17 | 1.15 | 1.03 | 1.08 | 1.00 | 0.97 | 1.09 | 0.81 | 0.82 | 0.87 | 1.44 | 1.39 | 0.94 | 1.11 | 0.93 |
N-Acetyl-L-carnosine | ME280066 | 0.90 | 1.14 | 0.93 | 1.08 | 1.21 | 0.94 | 1.48 | 1.23 | 1.16 | 1.05 | 0.81 | 1.09 | 0.80 | 0.79 | 0.83 | 0.81 | 1.08 | 0.75 | 0.90 | 1.00 | 1.15 | 1.03 | 1.24 | 1.16 | 1.06 | 0.90 | 1.00 | 1.06 | 0.95 | 0.73 | 0.83 |
N-Methylproline | ME280192 | 1.08 | 0.99 | 1.04 | 1.07 | 1.08 | 0.93 | 1.48 | 0.96 | 0.97 | 1.05 | 0.87 | 1.06 | 0.78 | 0.91 | 0.93 | 0.81 | 1.17 | 0.83 | 1.06 | 1.04 | 1.09 | 0.71 | 1.19 | 0.89 | 0.86 | 0.85 | 1.12 | 1.04 | 1.21 | 0.83 | 0.90 |
Glycerophosphocholine | ME280045 | 1.19 | 1.10 | 1.14 | 0.86 | 1.30 | 1.06 | 1.11 | 0.92 | 1.03 | 1.16 | 0.76 | 1.08 | 1.01 | 0.83 | 1.08 | 0.90 | 0.94 | 0.77 | 0.85 | 1.03 | 1.31 | 0.97 | 0.89 | 0.90 | 0.73 | 0.90 | 0.94 | 0.96 | 0.90 | 1.21 | 0.97 |
Spermidine | ME280084 | 1.10 | 1.07 | 0.97 | 1.08 | 1.02 | 1.04 | 0.85 | 0.95 | 0.87 | 0.90 | 1.24 | 0.90 | 0.85 | 1.12 | 0.86 | 0.65 | 0.98 | 0.79 | 0.83 | 1.05 | 1.28 | 0.84 | 1.22 | 0.90 | 1.09 | 1.05 | 1.04 | 1.25 | 0.75 | 1.25 | 0.94 |
trans-3^-Hydroxycotinine | ME280092 | 1.07 | 0.89 | 1.09 | 1.23 | 0.75 | 0.99 | 1.03 | 1.07 | 0.95 | 0.87 | 1.08 | 0.79 | 0.77 | 1.22 | 0.91 | 0.85 | 0.99 | 0.95 | 0.90 | 0.96 | 1.02 | 1.20 | 0.95 | 1.13 | 1.09 | 1.19 | 1.03 | 1.45 | 0.94 | 0.85 | 1.05 |
Ser-Tyr | ME280082 | 0.91 | 1.11 | 1.11 | 1.09 | 1.57 | 0.94 | 1.00 | 0.90 | 1.03 | 0.91 | 1.02 | 0.67 | 0.86 | 1.08 | 1.20 | 1.09 | 1.01 | 0.91 | 1.05 | 0.99 | 1.04 | 1.05 | 0.80 | 1.01 | 1.08 | 1.02 | 0.81 | 0.90 | 1.06 | 1.06 | 0.75 |
(2R)-3-Hydroxyisovaleroylcarnitine | ME280014 | 0.91 | 1.14 | 1.16 | 1.26 | 0.92 | 1.06 | 0.85 | 1.14 | 1.08 | 1.17 | 1.19 | 1.13 | 0.99 | 1.15 | 1.00 | 0.75 | 0.71 | 1.00 | 0.93 | 1.02 | 1.09 | 0.66 | 1.11 | 0.92 | 0.83 | 0.86 | 1.04 | 0.96 | 0.91 | 0.94 | 1.00 |
Isovaleryl-L-carnitine | ME280051 | 0.95 | 1.14 | 0.89 | 0.96 | 1.03 | 1.06 | 1.09 | 1.08 | 1.05 | 1.24 | 1.08 | 1.14 | 1.02 | 1.07 | 1.52 | 1.15 | 0.77 | 0.87 | 0.87 | 0.87 | 1.15 | 0.63 | 1.25 | 0.90 | 0.97 | 1.11 | 1.03 | 0.87 | 0.76 | 0.97 | 1.26 |
Acetylcarnitine | ME280136 | 0.91 | 1.11 | 1.13 | 1.06 | 0.97 | 1.09 | 0.99 | 1.01 | 1.09 | 1.20 | 0.94 | 1.15 | 0.91 | 1.07 | 1.16 | 0.92 | 0.86 | 0.90 | 0.88 | 1.00 | 0.99 | 0.73 | 1.11 | 1.03 | 0.98 | 1.09 | 0.98 | 0.94 | 0.88 | 0.87 | 1.03 |
Carnitine | ME280153 | 0.88 | 1.01 | 0.99 | 1.13 | 0.91 | 1.13 | 1.06 | 1.00 | 1.08 | 1.30 | 0.96 | 1.12 | 1.01 | 1.02 | 1.33 | 0.97 | 0.86 | 0.95 | 1.00 | 0.94 | 1.03 | 0.70 | 1.36 | 0.90 | 0.95 | 1.00 | 1.06 | 0.90 | 0.91 | 0.89 | 0.94 |
N-Acetylphenylalanine | ME280123 | 0.96 | 0.89 | 0.84 | 0.92 | 1.29 | 0.89 | 0.96 | 0.95 | 1.11 | 1.42 | 1.26 | 1.04 | 1.02 | 0.75 | 1.13 | 1.06 | 0.84 | 0.82 | 1.09 | 0.87 | 1.05 | 0.92 | 1.16 | 1.10 | 1.15 | 1.01 | 1.13 | 0.96 | 1.06 | 1.05 | 0.99 |
N-Acetyltryptophan | ME280188 | 1.13 | 0.94 | 0.91 | 1.05 | 1.18 | 1.01 | 0.86 | 0.87 | 1.25 | 1.11 | 0.97 | 0.96 | 1.07 | 0.83 | 1.18 | 0.92 | 0.80 | 0.78 | 0.89 | 1.10 | 0.85 | 0.84 | 1.14 | 0.95 | 0.87 | 1.01 | 0.91 | 1.00 | 1.01 | 1.03 | 1.01 |
3-Hydroxyproline | ME280105 | 0.86 | 0.94 | 0.98 | 1.05 | 0.81 | 0.88 | 1.17 | 1.33 | 0.93 | 1.04 | 0.98 | 1.20 | 1.03 | 1.04 | 0.94 | 1.06 | 0.84 | 1.06 | 0.94 | 1.08 | 0.88 | 0.97 | 1.02 | 0.96 | 0.92 | 0.85 | 0.90 | 0.95 | 0.96 | 1.22 | 0.74 |
Arg-Gly | ME280029 | 0.94 | 1.06 | 0.93 | 0.98 | 1.13 | 0.79 | 1.01 | 1.58 | 0.81 | 0.79 | 1.13 | 1.01 | 1.26 | 1.00 | 1.28 | 0.90 | 0.94 | 1.14 | 1.16 | 1.02 | 0.84 | 1.09 | 0.98 | 0.92 | 0.90 | 0.93 | 0.90 | 0.80 | 0.90 | 1.08 | 0.72 |
Kynurenine | ME280178 | 0.97 | 1.27 | 0.99 | 1.09 | 0.96 | 0.83 | 0.90 | 0.94 | 1.27 | 0.92 | 0.94 | 0.92 | 0.90 | 1.28 | 1.01 | 0.95 | 0.92 | 0.92 | 0.84 | 1.01 | 1.09 | 0.86 | 1.18 | 0.96 | 0.93 | 1.17 | 0.94 | 1.24 | 1.01 | 0.85 | 0.85 |
Cystathionine | ME280159 | 0.86 | 1.16 | 0.83 | 0.95 | 1.02 | 0.79 | 1.06 | 1.21 | 1.06 | 0.94 | 1.07 | 0.92 | 1.06 | 1.19 | 1.15 | 0.72 | 1.18 | 1.06 | 1.26 | 0.92 | 0.92 | 1.04 | 1.20 | 1.10 | 0.88 | 1.10 | 1.23 | 0.97 | 0.85 | 0.88 | 0.87 |
Arg-Ala | ME280026 | 0.87 | 0.90 | 0.91 | 1.19 | 1.19 | 1.00 | 1.02 | 1.22 | 0.80 | 0.91 | 1.01 | 1.06 | 0.94 | 0.82 | 1.05 | 0.73 | 1.08 | 1.07 | 1.42 | 1.00 | 0.95 | 1.12 | 0.96 | 1.12 | 0.74 | 0.97 | 0.92 | 1.07 | 0.96 | 1.11 | 0.89 |
Leu-Arg | ME280056 | 0.96 | 1.05 | 0.91 | 1.29 | 1.03 | 1.12 | 1.06 | 1.22 | 0.98 | 0.73 | 0.95 | 0.82 | 0.90 | 1.05 | 0.91 | 0.81 | 1.25 | 0.87 | 1.15 | 1.03 | 0.87 | 0.98 | 0.92 | 1.11 | 0.94 | 0.99 | 1.13 | 1.09 | 0.93 | 0.88 | 0.96 |
Homoarginine | ME280175 | 0.95 | 1.05 | 0.76 | 0.97 | 1.01 | 0.97 | 0.97 | 1.24 | 0.96 | 0.99 | 1.03 | 0.91 | 0.97 | 0.95 | 0.99 | 0.98 | 1.45 | 1.23 | 1.07 | 0.99 | 0.91 | 1.29 | 0.95 | 0.93 | 1.04 | 0.93 | 1.00 | 0.86 | 0.77 | 1.10 | 0.85 |
N-Methyllysine | ME280191 | 0.92 | 0.98 | 0.88 | 1.00 | 1.05 | 0.91 | 0.96 | 1.14 | 0.93 | 0.98 | 1.18 | 1.09 | 0.90 | 0.99 | 1.02 | 1.00 | 1.17 | 1.39 | 1.16 | 0.93 | 0.90 | 1.46 | 1.04 | 0.93 | 0.95 | 0.91 | 1.00 | 0.95 | 0.81 | 0.95 | 0.90 |
1_Val-Tyr-Val iSTD | ME280013 | 1.19 | 1.04 | 0.84 | 1.04 | 0.97 | 1.07 | 0.91 | 0.98 | 1.01 | 0.87 | 1.00 | 0.99 | 1.00 | 0.90 | 0.99 | 1.17 | 1.39 | 1.16 | 0.79 | 0.96 | 0.95 | 1.18 | 1.31 | 0.93 | 0.84 | 0.93 | 0.98 | 1.11 | 0.87 | 0.91 | 0.92 |
Methioninesulfoxide B | ME280182 | 1.25 | 1.18 | 0.69 | 0.81 | 1.02 | 1.12 | 1.06 | 1.22 | 1.04 | 0.99 | 1.04 | 1.07 | 0.81 | 0.78 | 1.05 | 1.22 | 1.14 | 1.13 | 0.93 | 0.95 | 1.19 | 1.28 | 0.84 | 0.81 | 1.06 | 1.07 | 0.92 | 0.86 | 0.78 | 1.02 | 0.92 |
Ornithine | ME280193 | 0.96 | 1.24 | 0.69 | 1.02 | 1.15 | 1.01 | 1.04 | 1.04 | 1.08 | 1.00 | 1.10 | 0.91 | 0.87 | 0.89 | 1.16 | 1.11 | 1.37 | 1.07 | 0.94 | 0.98 | 1.03 | 1.38 | 0.84 | 0.91 | 0.96 | 1.02 | 0.79 | 0.77 | 0.71 | 0.97 | 1.15 |
Asparagine | ME280148 | 0.87 | 1.07 | 0.84 | 1.00 | 0.99 | 0.91 | 1.07 | 0.94 | 1.01 | 0.90 | 1.23 | 0.93 | 1.05 | 0.97 | 0.91 | 1.04 | 1.21 | 0.84 | 0.91 | 1.06 | 0.95 | 1.28 | 0.97 | 0.88 | 0.99 | 0.96 | 0.83 | 0.99 | 0.89 | 0.96 | 1.18 |
Phenylalanine | ME280195 | 1.14 | 1.02 | 0.84 | 0.90 | 1.04 | 0.92 | 0.99 | 0.95 | 1.02 | 0.95 | 1.22 | 0.98 | 0.97 | 0.93 | 1.05 | 1.17 | 1.20 | 0.95 | 0.90 | 0.97 | 1.02 | 1.17 | 1.14 | 0.93 | 0.92 | 0.95 | 0.99 | 1.01 | 0.87 | 0.98 | 1.05 |
Proline | ME280197 | 1.12 | 1.14 | 0.75 | 0.87 | 1.14 | 0.98 | 1.11 | 0.99 | 0.96 | 0.98 | 1.08 | 0.99 | 0.93 | 0.87 | 1.02 | 1.05 | 1.13 | 0.87 | 0.92 | 1.03 | 1.08 | 1.12 | 0.89 | 0.94 | 1.01 | 1.02 | 0.85 | 0.94 | 0.96 | 0.99 | 1.09 |
Aspartic acid | ME280149 | 1.07 | 1.12 | 1.00 | 0.85 | 1.15 | 1.05 | 0.94 | 0.95 | 0.90 | 0.90 | 1.13 | 0.81 | 1.04 | 1.07 | 0.91 | 1.22 | 1.07 | 0.92 | 0.93 | 0.99 | 0.88 | 1.12 | 0.86 | 0.83 | 0.92 | 1.08 | 0.96 | 0.97 | 1.14 | 0.98 | 1.32 |
Glutamic acid | ME280166 | 0.95 | 1.20 | 1.19 | 0.95 | 1.14 | 0.94 | 0.92 | 1.05 | 1.01 | 0.89 | 1.17 | 0.73 | 0.93 | 1.06 | 0.92 | 1.08 | 1.19 | 1.02 | 0.90 | 0.96 | 0.95 | 1.19 | 0.87 | 0.91 | 0.98 | 0.97 | 0.96 | 0.95 | 1.25 | 0.97 | 1.04 |
Gly-val | ME280171 | 1.29 | 0.94 | 0.76 | 0.91 | 1.07 | 0.93 | 1.33 | 1.06 | 1.04 | 0.93 | 1.10 | 0.95 | 0.82 | 0.91 | 0.91 | 0.88 | 0.94 | 0.90 | 0.98 | 1.00 | 1.29 | 1.03 | 0.99 | 0.94 | 0.89 | 0.96 | 1.18 | 1.08 | 0.92 | 0.93 | 1.12 |
N-.alpha.-Acetyl-L-arginine | ME280063 | 1.12 | 1.03 | 0.84 | 1.05 | 1.13 | 1.15 | 1.17 | 1.06 | 1.14 | 0.95 | 0.93 | 0.85 | 1.01 | 0.75 | 1.27 | 0.94 | 0.83 | 0.93 | 0.86 | 0.99 | 1.17 | 1.03 | 1.05 | 0.99 | 1.10 | 0.91 | 1.02 | 1.06 | 0.84 | 1.02 | 0.90 |
Pyridoxamine | ME280200 | 1.06 | 1.03 | 1.02 | 0.95 | 1.13 | 0.93 | 1.40 | 1.13 | 1.17 | 1.14 | 0.94 | 1.08 | 1.02 | 0.87 | 1.25 | 0.96 | 1.07 | 0.80 | 0.83 | 0.94 | 1.08 | 0.88 | 1.05 | 0.94 | 0.92 | 0.91 | 1.07 | 1.09 | 0.90 | 0.92 | 0.89 |
N.alpha.-Methyl-L-lysine | ME280065 | 0.93 | 0.90 | 0.93 | 1.18 | 1.30 | 0.85 | 0.90 | 0.97 | 0.92 | 0.98 | 1.08 | 0.94 | 0.81 | 0.81 | 0.98 | 0.89 | 1.17 | 1.08 | 1.08 | 0.95 | 0.97 | 1.17 | 0.89 | 1.09 | 0.97 | 1.10 | 1.03 | 1.30 | 1.00 | 0.94 | 1.20 |
Pantothenic acid | ME280194 | 0.90 | 1.04 | 0.97 | 1.20 | 1.23 | 0.79 | 0.96 | 1.08 | 1.07 | 0.86 | 1.03 | 0.91 | 0.89 | 0.89 | 0.81 | 0.80 | 0.96 | 0.98 | 0.95 | 1.00 | 1.04 | 1.29 | 0.84 | 1.00 | 1.01 | 1.10 | 1.02 | 1.23 | 1.03 | 1.02 | 1.10 |
Pyridoxal | ME280077 | 1.03 | 1.28 | 0.98 | 1.08 | 1.03 | 0.97 | 0.97 | 1.14 | 1.06 | 0.80 | 1.17 | 0.99 | 0.84 | 1.02 | 0.96 | 1.11 | 1.09 | 1.22 | 1.17 | 0.84 | 0.98 | 1.05 | 0.98 | 1.22 | 1.02 | 0.80 | 1.22 | 1.01 | 1.05 | 0.82 | 0.97 |
Glu-Lys | ME280043 | 0.76 | 1.09 | 0.99 | 0.93 | 0.96 | 0.84 | 0.99 | 1.13 | 1.19 | 0.77 | 1.06 | 0.84 | 0.95 | 1.19 | 1.18 | 0.89 | 1.18 | 1.36 | 1.02 | 0.95 | 1.02 | 1.26 | 0.98 | 0.97 | 0.95 | 0.99 | 1.08 | 0.97 | 0.92 | 1.03 | 0.87 |
Glu-Thr | ME280170 | 0.92 | 1.08 | 1.04 | 0.95 | 1.18 | 0.91 | 0.99 | 1.14 | 1.10 | 0.80 | 0.97 | 0.77 | 0.99 | 1.03 | 1.17 | 1.00 | 1.08 | 1.12 | 0.88 | 0.98 | 1.14 | 1.13 | 0.98 | 0.91 | 1.03 | 1.10 | 1.03 | 0.91 | 0.91 | 1.03 | 0.86 |
gamma-Glutamylleucine | ME280163 | 1.13 | 1.12 | 0.98 | 0.89 | 1.20 | 1.00 | 0.94 | 1.02 | 1.11 | 0.98 | 1.13 | 0.77 | 0.87 | 1.09 | 1.11 | 1.01 | 1.01 | 1.01 | 0.83 | 0.96 | 1.12 | 1.15 | 0.93 | 0.90 | 0.96 | 1.05 | 0.99 | 0.90 | 0.99 | 1.08 | 0.98 |
Glu-Phe | ME280044 | 0.98 | 1.04 | 0.98 | 0.88 | 1.15 | 0.96 | 0.93 | 1.01 | 1.05 | 0.90 | 1.18 | 0.75 | 0.96 | 1.04 | 1.12 | 1.14 | 1.13 | 0.91 | 0.89 | 0.94 | 1.08 | 1.19 | 0.90 | 0.94 | 1.02 | 1.09 | 0.99 | 0.97 | 1.01 | 1.16 | 1.03 |
gamma-Glutamylmethionine | ME280164 | 0.98 | 0.95 | 0.82 | 0.95 | 1.17 | 0.91 | 0.92 | 1.31 | 1.14 | 0.78 | 1.03 | 0.84 | 0.83 | 0.99 | 1.26 | 1.10 | 1.15 | 1.12 | 0.80 | 0.94 | 1.21 | 1.14 | 0.88 | 0.96 | 1.12 | 1.10 | 0.94 | 0.91 | 0.95 | 1.25 | 0.86 |
Glu-Arg | ME280041 | 0.87 | 1.02 | 0.87 | 1.01 | 1.21 | 0.95 | 1.03 | 1.17 | 1.10 | 0.74 | 1.07 | 0.74 | 0.91 | 0.93 | 1.12 | 0.94 | 1.27 | 1.25 | 0.91 | 0.93 | 1.20 | 1.20 | 0.87 | 0.98 | 1.04 | 0.93 | 1.10 | 0.88 | 0.98 | 1.12 | 1.01 |
Glu-Gln | ME280165 | 0.88 | 0.99 | 0.96 | 1.05 | 1.04 | 0.96 | 0.89 | 1.07 | 1.05 | 0.78 | 1.04 | 0.77 | 0.90 | 1.04 | 1.17 | 1.15 | 1.33 | 1.14 | 0.89 | 0.97 | 1.10 | 1.32 | 0.88 | 0.94 | 1.02 | 1.01 | 0.96 | 0.86 | 0.97 | 1.13 | 0.92 |
Ser-Glu | ME280078 | 0.82 | 0.99 | 0.99 | 1.00 | 1.13 | 0.89 | 1.00 | 1.10 | 1.06 | 0.72 | 1.04 | 0.81 | 0.88 | 0.95 | 1.27 | 1.06 | 1.32 | 1.07 | 0.90 | 0.96 | 1.06 | 1.31 | 0.96 | 0.93 | 1.06 | 0.98 | 1.04 | 0.89 | 0.97 | 1.06 | 0.98 |
4-Acetamidobutyric acid | ME280131 | 0.93 | 1.14 | 0.96 | 1.08 | 1.24 | 0.84 | 1.10 | 1.05 | 0.95 | 0.86 | 1.24 | 0.90 | 0.87 | 0.88 | 0.96 | 0.81 | 1.04 | 0.92 | 0.97 | 1.02 | 1.17 | 1.04 | 0.81 | 1.05 | 1.05 | 0.91 | 1.18 | 1.01 | 1.01 | 0.89 | 0.98 |
L-Homocitrulline | ME280058 | 0.90 | 1.11 | 0.93 | 1.10 | 1.02 | 0.93 | 1.25 | 1.00 | 1.01 | 1.01 | 1.11 | 1.10 | 0.87 | 0.85 | 0.98 | 0.80 | 0.94 | 1.04 | 1.07 | 1.03 | 1.04 | 1.21 | 0.92 | 1.01 | 1.00 | 0.82 | 0.95 | 1.10 | 0.98 | 0.86 | 0.90 |
Adenosine | ME280138 | 1.03 | 0.96 | 1.06 | 1.06 | 0.87 | 1.07 | 0.92 | 1.01 | 0.94 | 1.07 | 0.95 | 0.85 | 0.85 | 0.98 | 1.07 | 1.09 | 0.92 | 0.92 | 0.90 | 1.08 | 1.05 | 0.89 | 0.98 | 0.99 | 0.99 | 1.03 | 1.16 | 1.01 | 1.05 | 1.00 | 0.82 |
Tryptamine | ME280093 | 1.09 | 1.14 | 1.01 | 1.16 | 1.07 | 1.05 | 0.90 | 0.94 | 1.05 | 0.87 | 1.08 | 1.00 | 0.94 | 1.07 | 0.95 | 0.92 | 1.10 | 0.88 | 0.78 | 1.03 | 1.04 | 0.92 | 1.07 | 0.99 | 0.84 | 1.04 | 0.93 | 1.04 | 1.09 | 0.98 | 0.90 |
Tryptophan | ME280209 | 1.09 | 1.14 | 1.00 | 1.18 | 1.03 | 1.00 | 0.91 | 0.93 | 1.07 | 0.89 | 1.07 | 1.03 | 0.97 | 1.06 | 0.98 | 0.90 | 1.13 | 0.89 | 0.79 | 1.02 | 1.02 | 0.91 | 1.08 | 0.95 | 0.84 | 1.04 | 0.93 | 1.07 | 1.06 | 0.99 | 0.90 |
Isoleucine | ME280177 | 1.16 | 1.11 | 0.95 | 1.11 | 1.13 | 0.97 | 0.93 | 1.11 | 1.02 | 1.05 | 1.16 | 1.00 | 0.82 | 1.17 | 0.98 | 0.86 | 0.93 | 0.94 | 0.90 | 1.05 | 1.07 | 0.87 | 0.99 | 0.86 | 0.80 | 0.88 | 1.06 | 1.01 | 0.93 | 0.91 | 0.96 |
Leucine | ME280179 | 1.21 | 1.09 | 0.91 | 0.96 | 1.12 | 0.99 | 0.98 | 1.07 | 1.04 | 1.05 | 1.09 | 0.97 | 0.86 | 1.03 | 1.02 | 0.96 | 0.99 | 0.93 | 0.90 | 1.04 | 1.07 | 0.95 | 0.96 | 0.94 | 0.91 | 0.95 | 1.02 | 0.92 | 0.89 | 0.93 | 1.00 |
Glutamine | ME280167 | 0.86 | 1.05 | 0.97 | 1.08 | 0.91 | 1.02 | 1.03 | 0.97 | 1.09 | 1.00 | 1.01 | 0.96 | 0.91 | 0.92 | 1.03 | 1.09 | 1.17 | 0.95 | 1.23 | 1.04 | 0.95 | 1.11 | 0.88 | 0.91 | 0.90 | 0.88 | 0.96 | 0.93 | 0.96 | 0.99 | 1.01 |
Gluconolactone | ME280042 | 0.89 | 0.82 | 0.98 | 1.23 | 0.91 | 0.78 | 0.89 | 1.20 | 1.17 | 1.00 | 0.95 | 0.96 | 0.75 | 0.91 | 0.96 | 0.95 | 1.18 | 1.30 | 0.91 | 1.02 | 1.15 | 1.03 | 1.00 | 1.11 | 1.03 | 0.88 | 1.16 | 1.06 | 0.99 | 0.95 | 0.78 |
1_D5-L-Glutamine iSTD | ME280007 | 0.91 | 0.95 | 0.93 | 1.15 | 0.88 | 0.99 | 1.02 | 1.06 | 1.10 | 0.91 | 0.98 | 0.92 | 0.87 | 0.88 | 1.07 | 1.04 | 1.20 | 1.24 | 1.07 | 1.02 | 0.99 | 1.16 | 0.88 | 0.97 | 0.95 | 0.84 | 1.06 | 1.00 | 0.95 | 0.97 | 0.93 |
1_D9-Betaine iSTD | ME280008 | 0.98 | 1.00 | 0.94 | 1.25 | 0.91 | 0.96 | 0.96 | 1.13 | 1.09 | 0.91 | 0.99 | 0.94 | 0.83 | 0.93 | 1.05 | 0.90 | 1.03 | 1.24 | 0.94 | 1.04 | 1.13 | 0.97 | 0.96 | 1.01 | 0.90 | 0.85 | 1.10 | 1.07 | 0.99 | 0.98 | 0.82 |
1_CUDA iSTD | ME279997 | 0.94 | 0.91 | 0.99 | 1.20 | 0.91 | 0.95 | 0.93 | 1.08 | 1.08 | 0.96 | 0.98 | 0.95 | 0.93 | 0.95 | 1.00 | 0.94 | 1.11 | 1.19 | 0.98 | 1.00 | 1.00 | 1.11 | 0.99 | 1.01 | 1.02 | 0.90 | 1.10 | 0.97 | 1.09 | 0.91 | 0.92 |
1_D9-TMAO iSTD | ME280012 | 0.92 | 0.99 | 0.97 | 1.18 | 0.92 | 0.98 | 0.94 | 1.09 | 1.03 | 0.94 | 1.00 | 0.93 | 0.87 | 0.98 | 1.02 | 0.99 | 1.14 | 1.28 | 0.97 | 0.98 | 1.06 | 1.10 | 0.95 | 1.01 | 0.96 | 0.90 | 1.08 | 1.03 | 1.03 | 0.98 | 0.88 |
1_D3-DL-Alanine iSTD | ME280002 | 1.00 | 0.97 | 0.93 | 1.11 | 0.94 | 1.02 | 0.96 | 1.12 | 1.01 | 0.97 | 0.96 | 0.96 | 0.95 | 0.92 | 0.99 | 0.95 | 1.14 | 1.18 | 0.93 | 1.01 | 1.06 | 1.06 | 0.97 | 1.03 | 0.98 | 0.89 | 1.09 | 1.04 | 0.96 | 0.96 | 0.89 |
1_D3-1-Methylnicotinamide iSTD | ME279998 | 0.97 | 1.01 | 1.00 | 1.14 | 0.95 | 0.97 | 0.96 | 1.08 | 1.05 | 0.95 | 0.98 | 0.98 | 0.91 | 0.97 | 1.01 | 0.96 | 1.03 | 1.14 | 0.95 | 1.01 | 1.07 | 1.02 | 0.98 | 0.99 | 0.95 | 0.91 | 1.07 | 1.04 | 1.00 | 0.99 | 0.89 |
1_D3-Creatinine iSTD | ME280001 | 0.98 | 0.99 | 0.99 | 1.13 | 0.93 | 0.98 | 0.96 | 1.07 | 1.04 | 0.94 | 0.99 | 0.97 | 0.90 | 0.96 | 1.02 | 0.96 | 1.01 | 1.13 | 0.96 | 1.02 | 1.08 | 1.00 | 0.97 | 1.00 | 0.98 | 0.94 | 1.05 | 1.03 | 1.01 | 1.00 | 0.90 |
1_D3-AC(2:0) iSTD | ME279999 | 0.99 | 0.96 | 0.99 | 1.13 | 0.95 | 0.96 | 0.95 | 1.11 | 1.02 | 0.91 | 1.01 | 0.94 | 0.89 | 0.96 | 0.95 | 0.97 | 1.10 | 1.25 | 0.93 | 1.01 | 1.06 | 1.07 | 0.91 | 1.01 | 0.96 | 0.92 | 1.08 | 1.04 | 1.01 | 0.98 | 0.92 |
1_D9-Crotonobetaine iSTD | ME280011 | 0.97 | 0.96 | 1.03 | 1.15 | 0.93 | 1.02 | 0.94 | 1.05 | 1.03 | 0.93 | 0.95 | 0.98 | 0.90 | 0.94 | 0.97 | 0.98 | 1.05 | 1.24 | 0.96 | 0.99 | 1.12 | 1.05 | 0.93 | 1.01 | 0.99 | 0.89 | 1.12 | 1.02 | 1.00 | 1.01 | 0.91 |
1_D3-Creatine iSTD | ME280000 | 0.99 | 0.91 | 0.98 | 1.15 | 0.92 | 0.98 | 0.93 | 1.12 | 1.07 | 0.95 | 0.96 | 0.96 | 0.88 | 0.93 | 0.98 | 0.96 | 1.08 | 1.25 | 0.95 | 1.01 | 1.09 | 1.05 | 0.93 | 1.03 | 0.99 | 0.91 | 1.10 | 1.05 | 0.98 | 0.99 | 0.88 |
1_D9-Choline iSTD | ME280010 | 0.98 | 1.00 | 0.98 | 1.13 | 0.93 | 0.98 | 0.96 | 1.08 | 1.04 | 0.93 | 0.96 | 0.96 | 0.91 | 0.96 | 1.01 | 0.96 | 1.09 | 1.18 | 0.94 | 1.00 | 1.10 | 1.03 | 0.99 | 1.04 | 0.97 | 0.92 | 1.06 | 1.03 | 0.99 | 1.00 | 0.89 |
1_D3-L-Carnitine iSTD | ME280006 | 0.97 | 0.96 | 0.98 | 1.14 | 0.94 | 0.97 | 0.95 | 1.08 | 1.04 | 0.92 | 0.97 | 0.97 | 0.90 | 0.93 | 1.00 | 0.97 | 1.08 | 1.23 | 0.94 | 1.01 | 1.07 | 1.04 | 0.95 | 1.01 | 0.98 | 0.92 | 1.10 | 1.05 | 1.00 | 1.00 | 0.87 |
1_D9-Butyrobetaine iSTD | ME280009 | 0.98 | 0.95 | 0.98 | 1.14 | 0.94 | 0.98 | 0.96 | 1.08 | 1.05 | 0.93 | 0.96 | 0.97 | 0.90 | 0.94 | 1.01 | 0.99 | 1.10 | 1.23 | 0.94 | 1.01 | 1.09 | 1.01 | 0.96 | 1.00 | 0.98 | 0.90 | 1.07 | 1.04 | 0.99 | 1.00 | 0.88 |
1_15N2-L-Arginine iSTD | ME279996 | 0.98 | 0.90 | 0.94 | 1.13 | 0.92 | 0.97 | 0.96 | 1.07 | 1.00 | 0.94 | 0.97 | 0.96 | 0.90 | 0.98 | 0.99 | 0.95 | 1.16 | 1.34 | 0.95 | 1.00 | 0.97 | 1.13 | 0.96 | 1.03 | 0.98 | 0.88 | 1.07 | 1.12 | 1.00 | 0.96 | 0.85 |
1_D3-DL-Aspartic acid iSTD | ME280003 | 0.97 | 0.96 | 0.96 | 1.12 | 0.95 | 1.00 | 0.97 | 1.14 | 1.00 | 0.93 | 0.96 | 0.98 | 0.93 | 0.94 | 0.99 | 0.95 | 1.17 | 1.30 | 0.90 | 0.98 | 1.05 | 1.10 | 0.97 | 1.02 | 0.99 | 0.91 | 1.13 | 1.04 | 0.93 | 0.96 | 0.90 |
1_D3-DL-Glutamic acid iSTD | ME280004 | 0.96 | 0.95 | 1.00 | 1.13 | 0.93 | 0.99 | 0.96 | 1.11 | 1.04 | 0.91 | 0.98 | 0.95 | 0.90 | 0.94 | 1.00 | 0.95 | 1.23 | 1.31 | 0.93 | 0.99 | 1.05 | 1.16 | 0.90 | 1.03 | 0.96 | 0.88 | 1.11 | 1.04 | 0.96 | 0.95 | 0.90 |
Tyrosine | ME280210 | 0.97 | 1.15 | 0.99 | 1.06 | 1.09 | 0.91 | 1.03 | 1.10 | 0.95 | 0.80 | 1.17 | 1.06 | 0.96 | 1.01 | 0.99 | 0.98 | 0.89 | 0.85 | 0.84 | 1.02 | 0.96 | 0.94 | 0.93 | 0.91 | 1.00 | 0.94 | 1.10 | 1.11 | 1.11 | 1.02 | 1.02 |
5-Methylcytosine | ME280023 | 1.12 | 0.94 | 1.00 | 1.02 | 0.99 | 0.95 | 1.04 | 1.22 | 1.01 | 0.87 | 0.94 | 1.00 | 0.99 | 1.05 | 1.00 | 0.90 | 0.91 | 1.13 | 0.88 | 1.01 | 0.96 | 0.90 | 1.12 | 0.95 | 1.04 | 1.02 | 0.97 | 1.08 | 0.86 | 1.14 | 0.95 |
Phenylacetylglutamine | ME280075 | 1.11 | 0.98 | 0.91 | 1.10 | 0.96 | 1.05 | 1.03 | 1.14 | 0.97 | 0.98 | 1.03 | 1.03 | 0.99 | 0.96 | 0.96 | 1.03 | 0.87 | 0.96 | 0.86 | 1.08 | 0.97 | 0.83 | 1.11 | 0.89 | 0.94 | 0.97 | 0.81 | 1.13 | 0.89 | 1.02 | 0.94 |
Agmatine | ME280140 | 0.97 | 0.93 | 0.96 | 1.10 | 1.00 | 0.99 | 1.19 | 1.11 | 0.94 | 0.94 | 0.98 | 1.08 | 0.91 | 0.87 | 1.06 | 0.93 | 0.90 | 0.98 | 1.02 | 1.04 | 1.10 | 0.91 | 1.13 | 0.95 | 0.94 | 0.90 | 0.97 | 1.02 | 0.96 | 1.03 | 0.92 |
Androsterone | ME280145 | 0.97 | 0.95 | 1.01 | 1.08 | 0.94 | 0.99 | 0.99 | 1.08 | 1.02 | 0.93 | 1.00 | 0.97 | 0.97 | 1.00 | 1.01 | 0.97 | 0.90 | 0.98 | 0.92 | 1.07 | 1.03 | 0.84 | 1.01 | 1.00 | 0.97 | 0.97 | 1.00 | 1.05 | 1.02 | 1.05 | 0.89 |
NG,NG-Dimethyl-L-arginine | ME280071 | 0.88 | 1.08 | 0.89 | 1.15 | 1.04 | 0.99 | 1.08 | 1.07 | 0.98 | 0.97 | 1.13 | 1.02 | 0.99 | 1.07 | 0.96 | 0.88 | 1.01 | 0.98 | 0.95 | 1.04 | 0.91 | 0.99 | 1.09 | 1.00 | 0.87 | 0.95 | 0.91 | 1.12 | 0.90 | 0.99 | 0.90 |
N,N-Dimethylarginine | ME280183 | 0.88 | 1.08 | 0.89 | 1.15 | 1.04 | 0.99 | 1.08 | 1.07 | 0.98 | 0.97 | 1.13 | 1.02 | 0.99 | 1.07 | 0.96 | 0.88 | 1.01 | 0.98 | 0.95 | 1.04 | 0.91 | 0.99 | 1.09 | 1.00 | 0.87 | 0.95 | 0.91 | 1.12 | 0.90 | 0.99 | 0.90 |
N-Acetylalanine | ME280185 | 1.06 | 0.99 | 0.89 | 1.10 | 1.02 | 0.88 | 0.98 | 1.03 | 1.07 | 0.97 | 1.10 | 0.89 | 1.05 | 1.02 | 1.00 | 0.82 | 1.04 | 0.96 | 1.03 | 1.02 | 1.01 | 1.11 | 0.93 | 1.13 | 0.96 | 0.84 | 1.01 | 1.09 | 0.98 | 0.98 | 0.94 |
DL-2-Methylglutamic acid | ME280160 | 0.88 | 1.02 | 0.94 | 1.08 | 1.05 | 0.93 | 1.20 | 0.99 | 1.06 | 0.98 | 0.97 | 0.91 | 0.83 | 1.06 | 0.94 | 0.84 | 0.97 | 1.00 | 0.95 | 1.07 | 0.95 | 1.01 | 0.97 | 1.09 | 1.00 | 0.96 | 0.99 | 1.13 | 0.99 | 0.89 | 0.90 |
Galactosamine | ME280115 | 0.90 | 1.01 | 0.94 | 1.06 | 0.99 | 0.90 | 0.96 | 1.08 | 1.05 | 1.01 | 1.00 | 0.90 | 0.88 | 1.13 | 0.99 | 0.88 | 0.91 | 0.96 | 1.04 | 1.07 | 1.01 | 1.03 | 0.92 | 1.12 | 0.90 | 0.96 | 1.08 | 1.13 | 1.07 | 0.85 | 0.89 |
Valine | ME280211 | 1.02 | 0.98 | 1.00 | 0.93 | 0.99 | 1.00 | 1.00 | 0.97 | 0.98 | 0.97 | 0.99 | 1.01 | 1.05 | 1.02 | 0.96 | 1.06 | 1.01 | 0.98 | 1.01 | 0.99 | 0.97 | 1.03 | 0.99 | 1.01 | 1.05 | 1.03 | 0.98 | 0.99 | 1.03 | 1.03 | 1.03 |
5-Aminovaleric acid | ME280107 | 1.02 | 0.98 | 1.00 | 0.93 | 0.99 | 1.00 | 1.00 | 0.97 | 0.98 | 0.97 | 0.99 | 1.01 | 1.05 | 1.02 | 0.96 | 1.06 | 1.01 | 0.98 | 1.01 | 0.99 | 0.97 | 1.03 | 0.99 | 1.01 | 1.05 | 1.03 | 0.98 | 0.99 | 1.03 | 1.03 | 1.03 |
Betaine | ME280111 | 1.02 | 0.98 | 1.00 | 0.93 | 0.99 | 1.00 | 1.00 | 0.97 | 0.98 | 0.97 | 0.99 | 1.01 | 1.05 | 1.02 | 0.96 | 1.06 | 1.01 | 0.98 | 1.01 | 0.99 | 0.97 | 1.03 | 0.99 | 1.01 | 1.05 | 1.03 | 0.98 | 0.99 | 1.03 | 1.03 | 1.03 |
3-Guanidinopropionic acid | ME280103 | 0.97 | 1.06 | 0.93 | 1.02 | 1.04 | 1.02 | 1.11 | 1.03 | 1.01 | 0.97 | 1.09 | 0.95 | 1.05 | 1.02 | 1.03 | 0.90 | 0.94 | 0.91 | 0.99 | 1.04 | 1.00 | 1.01 | 0.98 | 0.94 | 0.88 | 0.97 | 0.95 | 0.98 | 1.01 | 0.95 | 1.04 |
Creatine | ME280158 | 0.97 | 1.06 | 0.93 | 1.02 | 1.04 | 1.02 | 1.11 | 1.03 | 1.01 | 0.97 | 1.09 | 0.95 | 1.05 | 1.02 | 1.03 | 0.90 | 0.94 | 0.91 | 0.99 | 1.04 | 1.00 | 1.01 | 0.98 | 0.94 | 0.88 | 0.97 | 0.95 | 0.98 | 1.01 | 0.95 | 1.04 |
Alanine | ME280142 | 0.96 | 1.06 | 0.85 | 0.95 | 1.07 | 0.97 | 1.10 | 1.02 | 0.92 | 1.11 | 1.07 | 1.02 | 0.98 | 0.88 | 0.90 | 0.92 | 1.13 | 0.89 | 0.99 | 1.07 | 0.96 | 1.13 | 1.00 | 0.94 | 0.94 | 0.95 | 0.92 | 0.99 | 1.06 | 0.91 | 1.00 |
Serine | ME280203 | 0.94 | 1.07 | 0.91 | 1.04 | 1.01 | 0.97 | 1.08 | 1.01 | 0.98 | 0.89 | 1.04 | 1.01 | 1.02 | 0.89 | 0.97 | 1.00 | 1.14 | 0.92 | 1.03 | 1.03 | 1.02 | 1.14 | 1.00 | 0.93 | 0.95 | 0.94 | 0.97 | 0.97 | 1.03 | 0.94 | 1.03 |
Anserine | ME280146 | 0.90 | 1.17 | 0.93 | 1.03 | 1.01 | 1.01 | 0.97 | 1.01 | 1.01 | 1.04 | 0.89 | 1.01 | 0.94 | 0.90 | 0.94 | 0.91 | 1.08 | 0.98 | 1.05 | 1.01 | 0.93 | 1.02 | 1.23 | 1.08 | 1.01 | 0.93 | 1.11 | 1.02 | 1.05 | 0.91 | 0.89 |
NEPSILON,NEPSILON,NEPSILON-TRIMETHYLLYSINE | ME280069 | 0.94 | 1.01 | 0.90 | 1.15 | 1.06 | 1.02 | 0.95 | 0.98 | 0.99 | 0.97 | 1.18 | 0.97 | 0.91 | 0.96 | 1.04 | 0.89 | 0.96 | 1.13 | 1.03 | 0.97 | 0.99 | 1.08 | 0.99 | 1.10 | 1.08 | 0.97 | 1.11 | 1.00 | 1.03 | 0.91 | 0.92 |
Glycyl-leucine | ME280046 | 0.92 | 1.06 | 1.01 | 1.08 | 1.12 | 0.93 | 1.03 | 0.94 | 1.11 | 0.98 | 1.13 | 0.99 | 1.00 | 0.93 | 1.02 | 0.93 | 0.93 | 0.96 | 0.91 | 0.96 | 1.04 | 1.02 | 1.08 | 1.04 | 1.04 | 0.93 | 1.07 | 1.04 | 1.03 | 1.01 | 0.98 |
N.alpha.-Acetyl-L-lysine | ME280064 | 0.92 | 1.06 | 1.01 | 1.08 | 1.12 | 0.93 | 1.03 | 0.94 | 1.11 | 0.98 | 1.13 | 0.99 | 1.00 | 0.93 | 1.02 | 0.93 | 0.93 | 0.96 | 0.91 | 0.96 | 1.04 | 1.02 | 1.08 | 1.04 | 1.04 | 0.93 | 1.07 | 1.04 | 1.03 | 1.01 | 0.98 |
Creatinine | ME280113 | 0.92 | 0.98 | 1.06 | 1.13 | 0.98 | 0.93 | 0.98 | 0.98 | 1.12 | 0.90 | 1.03 | 0.97 | 1.00 | 0.89 | 0.98 | 0.82 | 0.95 | 0.92 | 0.97 | 1.04 | 1.02 | 0.91 | 1.13 | 1.02 | 1.02 | 0.91 | 1.13 | 1.05 | 1.05 | 1.02 | 0.93 |
Leu-Pro | ME280057 | 0.91 | 1.03 | 1.01 | 1.08 | 1.06 | 1.02 | 1.06 | 0.95 | 1.06 | 0.98 | 1.01 | 1.01 | 1.01 | 0.96 | 0.97 | 0.82 | 0.95 | 0.94 | 0.98 | 1.03 | 1.00 | 0.93 | 1.15 | 0.92 | 0.98 | 0.94 | 1.06 | 1.07 | 1.07 | 0.97 | 0.90 |
Thr-Ala | ME280088 | 1.02 | 1.07 | 0.87 | 0.99 | 1.21 | 0.95 | 1.24 | 1.03 | 1.15 | 1.04 | 1.07 | 0.92 | 0.85 | 0.92 | 1.11 | 0.99 | 0.96 | 1.01 | 0.91 | 0.97 | 0.90 | 1.06 | 0.90 | 1.01 | 0.99 | 1.03 | 0.93 | 1.06 | 1.00 | 0.97 | 1.03 |
Targinine | ME280204 | 0.92 | 1.09 | 0.79 | 1.06 | 1.07 | 0.95 | 1.02 | 1.11 | 0.99 | 0.92 | 1.05 | 1.01 | 0.92 | 0.98 | 1.18 | 1.01 | 1.22 | 1.07 | 0.98 | 1.01 | 1.08 | 1.22 | 1.02 | 0.95 | 0.94 | 1.00 | 0.84 | 0.91 | 0.73 | 1.06 | 0.85 |
Citrulline | ME280156 | 0.98 | 1.05 | 0.83 | 0.95 | 1.12 | 1.01 | 1.04 | 1.06 | 1.15 | 1.06 | 0.98 | 0.95 | 0.88 | 0.82 | 1.09 | 1.04 | 1.06 | 0.99 | 1.09 | 1.01 | 1.07 | 1.04 | 0.97 | 0.95 | 1.05 | 0.90 | 0.99 | 0.88 | 0.93 | 1.02 | 1.04 |
Histidine | ME280174 | 0.96 | 0.98 | 0.90 | 0.95 | 1.09 | 0.91 | 1.09 | 1.17 | 1.03 | 1.00 | 0.99 | 1.03 | 0.96 | 0.85 | 1.09 | 1.04 | 1.11 | 0.99 | 0.97 | 0.96 | 1.10 | 1.24 | 0.92 | 1.05 | 0.97 | 0.95 | 0.98 | 0.96 | 0.90 | 0.99 | 1.11 |
Methionine | ME280181 | 1.08 | 1.20 | 0.86 | 0.91 | 1.03 | 1.00 | 1.18 | 1.13 | 1.03 | 0.99 | 1.04 | 1.11 | 0.94 | 0.85 | 0.99 | 0.92 | 0.99 | 1.01 | 0.94 | 1.01 | 1.18 | 1.06 | 0.99 | 0.89 | 0.92 | 0.94 | 0.92 | 0.94 | 0.94 | 0.98 | 1.01 |
Lysine | ME280180 | 0.87 | 1.11 | 0.86 | 1.11 | 1.07 | 0.92 | 1.07 | 1.14 | 1.09 | 0.89 | 1.03 | 1.03 | 0.89 | 1.02 | 1.06 | 0.85 | 1.13 | 1.10 | 0.94 | 1.02 | 1.09 | 1.14 | 1.00 | 0.96 | 0.89 | 0.93 | 1.00 | 0.87 | 0.82 | 1.03 | 0.97 |
Arginine | ME280147 | 0.99 | 1.09 | 0.90 | 1.07 | 1.03 | 0.96 | 1.07 | 1.13 | 1.04 | 0.93 | 1.00 | 0.96 | 0.92 | 0.93 | 1.03 | 0.93 | 1.03 | 1.06 | 0.99 | 1.02 | 1.08 | 1.00 | 1.02 | 0.96 | 0.97 | 0.89 | 1.03 | 0.96 | 0.91 | 1.04 | 0.94 |
Threonine | ME280207 | 0.99 | 1.13 | 0.88 | 1.02 | 1.08 | 0.99 | 1.00 | 1.13 | 1.02 | 0.94 | 0.93 | 0.96 | 0.98 | 0.94 | 1.04 | 0.90 | 1.03 | 0.98 | 0.92 | 1.05 | 1.14 | 1.03 | 1.02 | 0.93 | 0.96 | 1.06 | 0.98 | 0.95 | 0.87 | 0.93 | 0.93 |
4-Aminobenzoic acid | ME280132 | 1.21 | 1.02 | 0.80 | 1.05 | 1.18 | 1.04 | 1.11 | 1.05 | 0.90 | 1.09 | 1.18 | 0.86 | 0.88 | 0.77 | 1.14 | 0.93 | 0.88 | 0.93 | 1.16 | 0.95 | 1.07 | 1.09 | 0.98 | 1.09 | 1.00 | 1.02 | 0.93 | 1.01 | 1.09 | 1.07 | 0.80 |
gamma-Aminobutyric Acid (GABA) | ME280162 | 1.04 | 1.07 | 0.89 | 0.93 | 1.20 | 0.94 | 0.93 | 1.00 | 0.98 | 0.86 | 1.11 | 1.03 | 1.06 | 0.96 | 1.14 | 1.00 | 0.97 | 1.06 | 0.97 | 0.95 | 0.94 | 0.97 | 0.92 | 1.14 | 1.01 | 1.00 | 1.01 | 1.08 | 0.95 | 1.17 | 1.04 |
N-Acetylmethionine | ME280187 | 1.03 | 1.01 | 0.81 | 0.87 | 1.20 | 0.87 | 0.98 | 1.30 | 1.12 | 1.14 | 1.15 | 1.01 | 1.05 | 0.73 | 1.10 | 0.82 | 0.94 | 1.05 | 1.00 | 0.96 | 0.96 | 0.97 | 0.99 | 1.07 | 1.10 | 0.89 | 1.02 | 0.99 | 1.00 | 1.09 | 1.03 |
N-alpha-Acetyl-L-ornithine | ME280068 | 1.00 | 1.15 | 1.05 | 1.00 | 1.10 | 0.85 | 1.26 | 1.12 | 1.00 | 1.16 | 1.21 | 1.14 | 0.86 | 0.94 | 1.12 | 0.88 | 0.79 | 0.80 | 1.15 | 0.94 | 1.01 | 1.01 | 1.07 | 0.81 | 0.92 | 0.89 | 1.13 | 1.04 | 1.14 | 0.83 | 1.02 |
Lys-Val | ME280062 | 0.80 | 0.98 | 1.08 | 1.14 | 0.97 | 0.85 | 1.01 | 0.97 | 0.90 | 1.08 | 1.15 | 0.91 | 1.06 | 1.06 | 0.94 | 0.74 | 1.01 | 1.27 | 1.26 | 1.02 | 0.79 | 1.12 | 0.99 | 1.11 | 0.82 | 0.94 | 1.17 | 0.98 | 1.11 | 0.75 | 0.89 |
Choline [M]+ | ME280155 | 0.94 | 0.96 | 1.13 | 0.96 | 1.06 | 1.00 | 0.95 | 0.90 | 0.90 | 1.22 | 1.09 | 0.94 | 1.08 | 0.94 | 0.96 | 0.91 | 0.89 | 0.89 | 1.25 | 1.03 | 0.92 | 0.97 | 1.02 | 1.01 | 0.93 | 0.91 | 1.06 | 1.04 | 1.02 | 0.95 | 1.02 |
Taurine | ME280205 | 1.00 | 0.97 | 1.00 | 1.00 | 1.26 | 0.95 | 1.09 | 0.89 | 0.88 | 1.03 | 0.99 | 0.86 | 0.99 | 1.03 | 0.98 | 0.86 | 0.94 | 0.91 | 1.11 | 1.10 | 0.92 | 0.98 | 0.98 | 1.12 | 0.82 | 0.90 | 1.03 | 0.88 | 1.13 | 0.80 | 1.06 |
N8-Acetylspermidine | ME280184 | 0.86 | 1.01 | 0.99 | 1.11 | 0.92 | 0.89 | 1.01 | 0.91 | 1.11 | 1.02 | 1.19 | 0.99 | 1.15 | 1.27 | 0.95 | 0.83 | 0.73 | 0.80 | 0.98 | 1.07 | 0.94 | 0.91 | 1.10 | 1.07 | 1.00 | 0.79 | 0.95 | 1.01 | 1.25 | 1.03 | 0.79 |
Putrescine | ME280126 | 0.93 | 1.09 | 1.07 | 1.00 | 0.94 | 0.90 | 1.22 | 1.03 | 1.00 | 0.92 | 1.13 | 0.96 | 1.05 | 1.04 | 0.97 | 0.92 | 0.71 | 0.90 | 1.05 | 1.04 | 1.01 | 0.88 | 1.12 | 0.94 | 0.82 | 0.89 | 1.02 | 1.04 | 1.30 | 1.03 | 0.83 |
4-Hydroxynonenal | ME280020 | 0.92 | 0.97 | 1.23 | 1.24 | 1.03 | 0.80 | 0.91 | 1.01 | 1.09 | 1.16 | 1.00 | 0.89 | 0.96 | 1.00 | 1.12 | 0.86 | 0.88 | 0.98 | 0.99 | 1.05 | 1.05 | 0.95 | 1.01 | 0.91 | 0.88 | 0.71 | 1.15 | 0.94 | 1.25 | 0.81 | 0.98 |
1-Methyl-L-histidine | ME280017 | 0.74 | 1.05 | 1.28 | 1.40 | 0.97 | 0.86 | 1.06 | 1.03 | 1.04 | 0.88 | 1.07 | 1.05 | 0.80 | 1.14 | 1.01 | 0.76 | 0.99 | 1.02 | 1.13 | 1.00 | 1.05 | 0.91 | 0.94 | 1.01 | 0.88 | 0.97 | 1.05 | 0.97 | 1.15 | 0.80 | 0.99 |
N-Methylhistidine | ME280190 | 0.90 | 1.13 | 1.09 | 1.17 | 1.06 | 0.84 | 1.14 | 1.09 | 1.07 | 1.01 | 1.01 | 1.01 | 0.85 | 0.97 | 0.87 | 0.82 | 1.07 | 0.93 | 1.04 | 0.98 | 0.99 | 1.04 | 1.09 | 1.11 | 0.79 | 0.92 | 1.18 | 1.03 | 1.06 | 0.84 | 1.00 |
1-Methyladenosine | ME280100 | 0.86 | 1.01 | 1.08 | 1.14 | 0.95 | 0.80 | 1.05 | 1.00 | 1.10 | 0.99 | 0.96 | 1.06 | 1.14 | 1.01 | 0.98 | 0.79 | 0.97 | 1.08 | 1.04 | 1.02 | 0.82 | 0.91 | 1.25 | 0.94 | 0.93 | 0.91 | 1.06 | 1.07 | 1.09 | 1.01 | 0.87 |
1-Methylguanosine | ME280101 | 0.83 | 0.88 | 1.18 | 1.09 | 0.87 | 0.83 | 0.95 | 1.17 | 1.15 | 0.93 | 0.93 | 0.99 | 1.02 | 1.08 | 1.01 | 0.83 | 1.02 | 1.05 | 1.08 | 0.98 | 0.94 | 0.89 | 1.20 | 1.12 | 0.89 | 0.87 | 1.32 | 1.03 | 1.05 | 1.10 | 0.86 |
Adenine | ME280137 | 0.81 | 1.04 | 0.93 | 1.14 | 0.97 | 0.89 | 1.04 | 0.98 | 1.19 | 0.96 | 1.18 | 0.83 | 0.79 | 0.96 | 0.96 | 0.92 | 0.90 | 0.96 | 1.29 | 1.01 | 0.87 | 0.94 | 1.11 | 1.00 | 1.08 | 0.87 | 1.07 | 1.10 | 1.26 | 0.90 | 1.02 |
N-Acetylcytidine | ME280121 | 0.92 | 0.98 | 1.12 | 1.08 | 1.09 | 0.87 | 1.08 | 0.96 | 1.19 | 0.78 | 1.03 | 0.93 | 0.92 | 1.16 | 1.08 | 0.91 | 0.92 | 0.99 | 1.07 | 0.95 | 0.93 | 0.90 | 1.11 | 1.03 | 1.08 | 1.00 | 1.09 | 1.07 | 1.10 | 0.96 | 1.00 |
Factors:
F1 | Genotype:A2m |
F2 | Genotype:Ahcy |
F3 | Genotype:Atp5b |
F4 | Genotype:Atp6v0d1 |
F5 | Genotype:C8a |
F6 | Genotype:Cdk4 |
F7 | Genotype:Dhfr |
F8 | Genotype:Dync1li1 |
F9 | Genotype:G6pd2 |
F10 | Genotype:Galc |
F11 | Genotype:Gnpda1 |
F12 | Genotype:Idh1 |
F13 | Genotype:Iqgap1 |
F14 | Genotype:Lmbrd1 |
F15 | Genotype:Mfap4 |
F16 | Genotype:Mmachc |
F17 | Genotype:Mvk |
F18 | Genotype:Nek2 |
F19 | Genotype:Npc2 |
F20 | Genotype:Null |
F21 | Genotype:Pebp1 |
F22 | Genotype:Phyh |
F23 | Genotype:Pipox |
F24 | Genotype:Plk1 |
F25 | Genotype:Pmm2 |
F26 | Genotype:Ptpn12 |
F27 | Genotype:Pttg1 |
F28 | Genotype:Rock1 |
F29 | Genotype:Sra1 |
F30 | Genotype:Ulk3 |
F31 | Genotype:Ywhaz |