Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Phenotyping Mouse blood metabolites in day and night in type 2 diabetes (Study ST001253)

Reversed phase (late) POSITIVE ION MODE (Analysis AN002080)

Metabolite	Structure	F1	F2	F3	F4
N-stearoyl-sphingosine (d18:1/18:0)	ME293374	1.24	2.62	0.06	0.12
protoporphyrin IX	ME293361	0.24	3.15	0.09	0.28
glycosyl-N-stearoyl-sphingosine (d18:1/18:0)	ME293434	0.69	3.00	0.12	0.12
sphingomyelin (d18:0/18:0, d19:0/17:0)	ME293508	0.44	2.87	0.24	0.29
1-(1-enyl-palmitoyl)-2-linoleoyl-GPE (P-16:0/18:2)	ME293492	0.33	0.33	1.76	1.48
linoleoyl-docosahexaenoyl-glycerol (18:2/22:6) [2]	ME293379	0.55	0.40	1.25	1.59
1-(1-enyl-palmitoyl)-2-oleoyl-GPC (P-16:0/18:1)	ME293493	0.33	0.82	1.21	1.42
1-(1-enyl-palmitoyl)-2-palmitoyl-GPC (P-16:0/16:0)	ME293495	0.45	0.66	1.47	1.31
1-(1-enyl-palmitoyl)-2-linoleoyl-GPC (P-16:0/18:2)	ME293491	0.37	0.54	1.48	1.45
sphingomyelin (d18:2/21:0, d16:2/23:0)	ME293522	0.40	0.58	1.54	1.38
1,2-dilinoleoyl-GPE (18:2/18:2)	ME293472	0.48	0.93	1.51	1.06
sphingomyelin (d18:1/21:0, d17:1/22:0, d16:1/23:0)	ME293515	0.51	0.72	1.58	1.16
sphingomyelin (d18:2/23:1)	ME293524	0.64	0.91	1.15	1.20
sphingomyelin (d18:2/24:2)	ME293526	0.58	0.90	1.13	1.25
1-myristoyl-2-palmitoyl-GPC (14:0/16:0)	ME293458	0.55	0.85	1.32	1.19
sphingomyelin (d18:1/22:2, d18:2/22:1, d16:1/24:2)	ME293517	0.54	0.84	1.23	1.27
1-palmitoyl-2-linoleoyl-GPI (16:0/18:2)	ME293486	0.84	0.64	1.15	1.30
1-stearoyl-2-linoleoyl-GPI (18:0/18:2)	ME293488	0.91	0.73	1.16	1.17
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPE (P-16:0/20:4)	ME293490	0.72	0.76	1.17	1.26
sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1)	ME293516	0.75	0.71	1.33	1.18
1-(1-enyl-palmitoyl)-GPE (P-16:0)	ME293450	0.91	0.90	0.95	1.17
1-lignoceroyl-GPC (24:0)	ME293437	0.82	0.97	1.02	1.12
1-oleoyl-2-linoleoyl-GPE (18:1/18:2)	ME293476	0.90	1.07	1.21	0.88
behenoyl sphingomyelin (d18:1/22:0)	ME293500	0.84	1.03	1.24	0.93
sphingomyelin (d18:1/20:1, d18:2/20:0)	ME293514	0.71	0.96	1.20	1.08
sphingomyelin (d18:2/23:0, d18:1/23:1, d17:1/24:1)	ME293523	0.82	0.97	1.16	1.03
1-(1-enyl-palmitoyl)-2-arachidonoyl-GPC (P-16:0/20:4)	ME293489	0.78	1.03	1.18	1.00
sphingomyelin (d18:2/16:0, d18:1/16:1)	ME293520	0.77	1.06	1.12	1.02
nervonoylcarnitine (C24:1)	ME293422	0.87	0.93	1.45	0.86
1-(1-enyl-stearoyl)-2-linoleoyl-GPE (P-18:0/18:2)	ME293497	0.83	0.84	1.28	1.06
1-linoleoyl-2-linolenoyl-GPC (18:2/18:3)	ME293456	0.85	0.86	1.33	1.01
1,2-dilinoleoyl-GPC (18:2/18:2)	ME293453	0.88	0.92	1.30	0.96
lignoceroylcarnitine (C24)	ME293416	0.80	0.94	1.34	0.97
1-(1-enyl-oleoyl)-GPE (P-18:1)	ME293448	1.07	0.89	0.83	1.15
1-linolenoyl-GPC (18:3)	ME293438	1.16	1.01	0.80	1.01
1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4)	ME293485	1.27	0.93	0.76	1.04
1-linoleoyl-GPE (18:2)	ME293440	1.14	0.92	1.06	0.94
1-palmitoyl-2-linoleoyl-GPC (16:0/18:2)	ME293464	0.99	1.01	1.09	0.95
1-(1-enyl-stearoyl)-GPE (P-18:0)	ME293451	0.99	1.04	0.93	1.01
N-behenoyl-sphingadienine (d18:2/22:0)	ME293372	1.00	0.99	0.92	1.06
5-dodecenoylcarnitine (C12:1)	ME293406	0.95	1.14	0.91	0.97
sphingomyelin (d18:2/24:1, d18:1/24:2)	ME293525	0.89	1.15	0.92	0.99
1-linoleoyl-GPC (18:2)	ME293439	0.98	1.17	0.80	1.00
1-palmitoyl-GPC (16:0)	ME293444	1.01	1.11	0.87	0.98
1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6)	ME293462	1.14	1.14	0.83	0.91
sphingomyelin (d18:1/24:1, d18:2/24:0)	ME293518	1.11	1.27	0.87	0.79
1-stearoyl-2-linoleoyl-GPC (18:0/18:2)	ME293470	1.06	1.22	0.94	0.82
lignoceroyl sphingomyelin (d18:1/24:0)	ME293501	1.02	1.29	0.89	0.82
sphingomyelin (d18:1/19:0, d19:1/18:0)	ME293512	0.49	1.26	1.22	0.97
1-(1-enyl-stearoyl)-2-oleoyl-GPE (P-18:0/18:1)	ME293498	0.84	1.21	0.99	0.94
sphingomyelin (d17:1/16:0, d18:1/15:0, d16:1/17:0)	ME293507	0.67	1.26	1.08	0.94
octadecanedioylcarnitine (C18-DC)	ME293423	0.81	1.24	0.78	1.06
margaroylcarnitine (C17)	ME293419	0.72	1.37	0.74	1.03
octanoylcarnitine (C8)	ME293425	0.69	1.30	0.73	1.10
1-(1-enyl-palmitoyl)-GPC (P-16:0)	ME293449	0.84	1.02	0.83	1.19
sphingomyelin (d18:2/14:0, d18:1/14:1)	ME293519	0.73	1.16	0.86	1.12
1,2-dipalmitoyl-GPC (16:0/16:0)	ME293454	0.76	1.11	0.77	1.19
cis-4-decenoylcarnitine (C10:1)	ME293410	0.71	1.18	0.73	1.19
1-(1-enyl-palmitoyl)-2-oleoyl-GPE (P-16:0/18:1)	ME293494	0.58	1.00	0.85	1.34
heme	ME293360	0.82	0.80	0.81	1.38
linoleoylcholine	ME293400	0.49	0.69	0.62	1.78
palmitoylcholine	ME293402	0.77	0.70	0.53	1.66
docosahexaenoylcholine	ME293399	0.67	1.00	0.42	1.54
1-linoleoyl-2-arachidonoyl-GPE (18:2/20:4)	ME293474	0.60	1.28	0.43	1.36
arachidonoylcarnitine (C20:4)	ME293407	0.73	1.22	0.39	1.35
stearoylcholine	ME293403	0.82	1.14	0.41	1.35
octadecenedioylcarnitine (C18:1-DC)	ME293424	0.95	1.12	0.56	1.19
arachidonoylcholine	ME293398	1.11	0.87	0.48	1.35
oleoylcholine	ME293401	1.22	1.00	0.43	1.21
1,2-dipalmitoyl-GPE (16:0/16:0)	ME293473	0.38	1.66	0.13	1.37
dihomo-linoleoylcarnitine (C20:2)	ME293413	0.53	2.37	0.34	0.58
linoleoylcarnitine (C18:2)	ME293418	0.60	2.18	0.41	0.65
glycosyl ceramide (d18:1/20:0, d16:1/22:0)	ME293431	0.92	2.17	0.47	0.43
glycosyl-N-palmitoyl-sphingosine (d18:1/16:0)	ME293433	0.84	2.40	0.40	0.33
decanoylcarnitine (C10)	ME293411	0.55	1.76	0.62	0.89
dihomo-linolenoylcarnitine (C20:3n3 or 6)	ME293412	0.55	1.84	0.31	1.01
linolenoylcarnitine (C18:3)	ME293417	0.50	1.85	0.46	0.94
oleoylcarnitine (C18:1)	ME293426	0.99	2.01	0.33	0.61
palmitoleoylcarnitine (C16:1)	ME293427	0.83	2.03	0.40	0.63
bilirubin (Z,Z)	ME293358	0.83	1.96	0.75	0.49
eicosenoylcarnitine (C20:1)	ME293414	0.70	1.93	0.49	0.74
behenoyl dihydrosphingomyelin (d18:0/22:0)	ME293499	0.72	1.83	0.75	0.66
glycosyl ceramide (d18:2/24:1, d18:1/24:2)	ME293432	0.69	1.95	0.64	0.64
stearoyl sphingomyelin (d18:1/18:0)	ME293528	0.72	1.92	0.65	0.64
beta-sitosterol	ME293531	1.12	1.82	0.49	0.57
myristoleoylcarnitine (C14:1)	ME293420	1.17	1.65	0.58	0.63
tricosanoyl sphingomyelin (d18:1/23:0)	ME293529	1.08	1.74	0.69	0.55
ceramide (d18:2/24:1, d18:1/24:2)	ME293371	1.30	1.60	0.38	0.71
1-stearoyl-2-oleoyl-GPC (18:0/18:1)	ME293471	1.44	1.61	0.54	0.53
campesterol	ME293532	1.31	1.77	0.54	0.47
ceramide (d18:1/20:0, d16:1/22:0, d20:1/18:0)	ME293370	1.43	1.70	0.43	0.52
sphinganine	ME293505	1.35	1.74	0.41	0.55
1-stearoyl-2-arachidonoyl-GPI (18:0/20:4)	ME293487	0.97	1.36	0.76	0.87
1-stearoyl-GPC (18:0)	ME293446	1.14	1.43	0.70	0.75
sphingomyelin (d18:2/18:1)	ME293521	1.05	1.49	0.79	0.71
sphingomyelin (d18:1/20:0, d16:1/22:0)	ME293513	0.89	1.35	0.97	0.80
sphingomyelin (d18:1/17:0, d17:1/18:0, d19:1/16:0)	ME293510	0.74	1.56	0.92	0.76
palmitoyl sphingomyelin (d18:1/16:0)	ME293503	0.88	1.58	0.82	0.72
sphingomyelin (d18:1/14:0, d16:1/16:0)	ME293509	0.95	1.57	0.77	0.71
palmitoyl dihydrosphingomyelin (d18:0/16:0)	ME293502	0.84	1.52	0.86	0.76
sphingomyelin (d18:1/18:1, d18:2/18:0)	ME293511	0.86	1.46	0.85	0.81
biliverdin	ME293359	0.94	1.43	0.88	0.77
retinal	ME293367	0.96	1.44	0.80	0.79
palmitoylcarnitine (C16)	ME293428	0.66	1.62	0.49	1.01
sphingadienine	ME293504	0.64	1.55	0.48	1.08
oleoyl ethanolamide	ME293397	0.94	1.53	0.60	0.85
sphingosine	ME293527	1.00	1.54	0.54	0.84
1-palmitoyl-2-oleoyl-GPE (16:0/18:1)	ME293480	0.79	1.45	0.54	1.05
1-palmitoyl-2-stearoyl-GPC (16:0/18:0)	ME293467	0.85	1.42	0.65	0.97
pentadecanoylcarnitine (C15)	ME293429	0.70	1.48	0.73	0.96
laurylcarnitine (C12)	ME293415	0.77	1.60	0.68	0.85
myristoylcarnitine (C14)	ME293421	0.78	1.57	0.61	0.91
stearoylcarnitine (C18)	ME293430	0.79	1.58	0.61	0.89
1-palmitoyl-2-linoleoyl-GPE (16:0/18:2)	ME293479	0.91	0.70	1.69	0.88
arachidoylcarnitine (C20)	ME293408	0.81	0.92	1.72	0.75
behenoylcarnitine (C22)	ME293409	0.82	0.83	1.64	0.86
linoleoyl-arachidonoyl-glycerol (18:2/20:4) [1]	ME293376	1.71	0.70	1.31	0.63
linoleoyl-linoleoyl-glycerol (18:2/18:2) [1]	ME293382	1.58	0.75	1.52	0.54
1-stearoyl-2-linoleoyl-GPE (18:0/18:2)	ME293482	1.34	0.88	1.55	0.56
1-palmitoyl-2-docosahexaenoyl-GPE (16:0/22:6)	ME293478	1.36	0.79	1.37	0.73
palmitoyl-arachidonoyl-glycerol (16:0/20:4) [1]	ME293389	1.47	0.67	1.32	0.79
linoleoyl-linolenoyl-glycerol (18:2/18:3) [1]	ME293380	1.68	0.53	1.89	0.44
linoleoyl-linolenoyl-glycerol (18:2/18:3) [2]	ME293381	1.23	0.59	1.95	0.62
carotene diol (3)	ME293366	2.52	1.35	0.43	0.15
oleoyl-oleoyl-glycerol (18:1/18:1) [1]	ME293386	2.23	1.76	0.25	0.11
N-palmitoyl-sphingosine (d18:1/16:0)	ME293373	1.47	1.96	0.39	0.31
oleoyl-oleoyl-glycerol (18:1/18:1) [2]	ME293387	1.63	2.11	0.31	0.15
4-cholesten-3-one	ME293530	1.56	1.71	0.54	0.37
gamma-tocopherol/beta-tocopherol	ME293363	1.75	1.64	0.50	0.34
palmitoyl-oleoyl-glycerol (16:0/18:1) [2]	ME293393	1.99	1.68	0.60	0.11
sphinganine-1-phosphate	ME293506	2.00	1.45	0.62	0.27
1-docosahexaenoylglycerol (22:6)	ME293452	2.38	0.70	0.85	0.50
linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2]	ME293377	1.80	0.82	1.07	0.62
stearoyl-linoleoyl-glycerol (18:0/18:2) [2]	ME293395	1.89	1.10	1.17	0.28
palmitoyl-linoleoyl-glycerol (16:0/18:2) [1]	ME293391	1.81	0.99	1.14	0.43
oleoyl-linoleoyl-glycerol (18:1/18:2) [1]	ME293384	1.73	1.10	1.05	0.45
palmitoyl-linoleoyl-glycerol (16:0/18:2) [2]	ME293392	1.67	1.08	1.12	0.47
carotene diol (1)	ME293364	1.77	1.28	0.60	0.55
1-stearoyl-2-arachidonoyl-GPC (18:0/20:4)	ME293468	1.54	1.30	0.69	0.62
3-hydroxyoleoylcarnitine	ME293404	1.64	1.17	0.75	0.63
stearoyl-arachidonoyl-glycerol (18:0/20:4) [1]	ME293394	1.68	1.25	0.73	0.55
palmitoleoyl-linoleoyl-glycerol (16:1/18:2) [1]	ME293388	1.89	1.11	0.69	0.56
diacylglycerol (16:1/18:2 [2], 16:0/18:3 [1])	ME293375	1.79	1.12	0.90	0.49
1-palmitoleoyl-2-linolenoyl-GPC (16:1/18:3)	ME293460	1.73	1.02	0.84	0.64
palmitoyl-arachidonoyl-glycerol (16:0/20:4) [2]	ME293390	1.77	1.07	0.81	0.60
carotene diol (2)	ME293365	1.90	1.21	0.84	0.39
oleoyl-arachidonoyl-glycerol (18:1/20:4) [2]	ME293383	2.04	1.20	0.70	0.40
1-myristoyl-2-arachidonoyl-GPC (14:0/20:4)	ME293457	2.16	1.07	0.63	0.47
1-palmitoyl-2-palmitoleoyl-GPC (16:0/16:1)	ME293466	2.07	0.94	0.67	0.61
N-palmitoyl-sphinganine (d18:0/16:0)	ME293396	1.28	1.14	1.30	0.54
1-stearoyl-2-oleoyl-GPE (18:0/18:1)	ME293483	1.26	1.13	1.17	0.64
retinol (Vitamin A)	ME293368	1.23	1.06	1.19	0.70
1-(1-enyl-stearoyl)-2-arachidonoyl-GPE (P-18:0/20:4)	ME293496	1.32	1.02	0.94	0.82
1-palmitoyl-GPE (16:0)	ME293445	1.37	0.96	1.07	0.77
3-hydroxypalmitoylcarnitine	ME293405	1.32	1.01	1.02	0.78
1-linoleoyl-2-arachidonoyl-GPC (18:2/20:4n6)	ME293455	1.45	1.09	0.84	0.75
1-palmitoyl-2-arachidonoyl-GPC (16:0/20:4n6)	ME293461	1.44	1.05	0.87	0.78
1-oleoyl-GPE (18:1)	ME293442	1.43	0.96	0.87	0.86
1-palmitoyl-2-arachidonoyl-GPE (16:0/20:4)	ME293477	1.54	0.87	0.86	0.86
1-stearoyl-2-arachidonoyl-GPE (18:0/20:4)	ME293481	1.56	1.05	0.97	0.64
1-palmitoyl-2-gamma-linolenoyl-GPC (16:0/18:3n6)	ME293463	1.56	0.85	1.04	0.76
linoleoyl-docosahexaenoyl-glycerol (18:2/22:6) [1]	ME293378	1.56	0.85	1.06	0.74
1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6)	ME293469	1.28	1.51	0.66	0.62
alpha-tocopherol	ME293362	1.42	1.47	0.74	0.52
oleoyl-linoleoyl-glycerol (18:1/18:2) [2]	ME293385	1.56	1.30	0.95	0.46
1-stearoyl-GPE (18:0)	ME293447	1.29	1.29	0.91	0.65
cholesterol	ME293533	1.40	1.27	0.90	0.60
ceramide (d16:1/24:1, d18:1/22:1)	ME293369	1.60	1.19	0.44	0.83
1-oleoyl-2-arachidonoyl-GPI (18:1/20:4)	ME293484	1.58	1.10	0.57	0.83
1-oleoyl-2-docosahexaenoyl-GPC (18:1/22:6)	ME293459	1.63	1.09	0.68	0.74
1-oleoyl-2-arachidonoyl-GPE (18:1/20:4)	ME293475	1.17	1.30	0.50	0.96
1-arachidonoyl-GPE (20:4n6)	ME293436	1.41	1.22	0.64	0.80
1-palmitoyl-2-oleoyl-GPC (16:0/18:1)	ME293465	1.33	1.31	0.67	0.75
1-arachidonoyl-GPC (20:4n6)	ME293435	1.47	1.32	0.55	0.73
1-oleoyl-GPC (18:1)	ME293441	1.33	1.40	0.53	0.76
1-palmitoleoyl-GPC (16:1)	ME293443	1.38	1.31	0.51	0.82

Factors:

F1	diabetes:db/db \| time of day:ZT17
F2	diabetes:db/db \| time of day:ZT5
F3	diabetes:db/m \| time of day:ZT17
F4	diabetes:db/m \| time of day:ZT5

Data matrix