Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Phenotyping Mouse blood metabolites in day and night in type 2 diabetes (Study ST001253)

HILIC NEGATIVE ION MODE (Analysis AN002082)

Metabolite	Structure	F1	F2	F3	F4
sucrose	ME293863	1.28	0.11	3.48	0.06
orotate	ME293913	0.38	2.61	0.34	0.48
dihydroorotate	ME293911	0.02	3.48	0.02	0.19
N-carbamoylaspartate	ME293912	0.19	3.09	0.11	0.35
gentisate	ME293859	2.23	0.51	1.36	0.44
ribose	ME293875	2.95	0.70	0.92	0.12
caffeic acid sulfate	ME293924	2.24	0.87	0.91	0.41
fructose	ME293864	2.37	1.25	0.59	0.23
ribitol	ME293873	0.14	1.86	0.17	1.33
gluconate	ME293921	1.23	2.24	0.43	0.21
itaconate	ME293888	1.52	1.82	0.40	0.39
mannitol/sorbitol	ME293865	0.51	2.03	0.24	0.92
glycerophosphoglycerol	ME293900	0.94	1.84	0.73	0.53
heptenedioate (C7:1-DC)	ME293897	0.89	1.79	0.65	0.65
N-glycolylneuraminate	ME293922	0.63	1.83	0.51	0.85
succinate	ME293889	0.66	2.00	0.56	0.67
quinolinate	ME293883	0.87	0.42	2.12	0.87
gamma-glutamylthreonine	ME293915	0.60	0.60	1.57	1.22
xylose	ME293878	0.28	0.86	1.32	1.35
ribose 1-phosphate	ME293879	1.23	1.47	1.63	0.11
ribulose/xylulose 5-phosphate	ME293880	1.24	0.85	2.06	0.34
tricarballylate	ME293890	1.28	0.99	1.77	0.38
erythritol	ME293920	0.81	1.60	0.63	0.86
alpha-ketoglutaramate	ME293840	0.94	1.46	0.74	0.83
fumarate	ME293886	0.75	1.44	0.84	0.89
methylmalonate (MMA)	ME293891	0.86	1.40	0.90	0.83
cystine	ME293855	0.61	1.17	1.02	1.09
lactate	ME293869	0.71	1.36	0.73	1.05
arabitol/xylitol	ME293871	0.78	1.21	0.81	1.08
glycerophosphoinositol	ME293907	0.91	1.17	0.80	1.04
2-hydroxybutyrate/2-hydroxyisobutyrate	ME293843	1.03	1.52	0.96	0.58
gulonate	ME293881	1.26	1.04	1.08	0.76
N-acetylalanine	ME293837	1.21	0.98	1.00	0.89
alpha-ketoglutarate	ME293885	1.18	0.93	1.14	0.87
malonate	ME293892	1.12	0.98	1.14	0.86
perfluorooctanesulfonic acid (PFOS)	ME293917	1.10	1.18	1.01	0.78
3-methylglutaconate	ME293848	1.17	1.23	0.96	0.74
adipate (C6-DC)	ME293895	1.19	1.19	1.00	0.73
isocitric lactone	ME293887	1.08	1.30	1.01	0.70
myo-inositol	ME293901	1.00	1.26	1.01	0.79
alanine	ME293836	0.94	1.09	1.09	0.91
orotidine	ME293914	1.18	1.09	0.85	0.91
allantoin	ME293910	1.00	1.09	0.94	0.96
N-acetylneuraminate	ME293862	1.09	1.12	0.96	0.87
3-hydroxy-3-methylglutarate	ME293903	1.37	1.17	0.99	0.64
sphingosine 1-phosphate	ME293908	1.33	1.25	1.09	0.55
glucuronate	ME293861	1.22	1.29	0.69	0.82
1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6)	ME293904	1.38	1.22	0.79	0.73
threonate	ME293882	1.27	1.18	0.89	0.77
pyruvate	ME293870	0.89	0.78	0.79	1.37
1-palmitoyl-2-oleoyl-GPI (16:0/18:1)	ME293906	1.02	0.72	1.04	1.19
maleate	ME293898	1.12	0.87	1.00	1.03
N-acetylglutamine	ME293842	1.04	0.92	1.04	1.02
glutarate (C5-DC)	ME293896	1.13	0.85	1.23	0.90
N-formylanthranilic acid	ME293857	1.19	0.80	1.24	0.90
3-methyl-2-oxobutyrate	ME293847	1.01	0.85	1.16	1.02
1-stearoyl-2-oleoyl-GPG (18:0/18:1)	ME293905	1.04	0.79	1.24	1.00
2-oxoadipate	ME293851	1.07	0.75	1.30	0.97
hypotaurine	ME293856	0.91	0.69	1.34	1.09
N-acetylglycine	ME293844	1.08	0.62	1.29	1.08
2,3-dihydroxyisovalerate	ME293919	0.69	1.07	1.44	0.87
N6-acetyllysine	ME293853	0.79	0.87	1.45	0.96
N-acetylserine	ME293845	0.87	0.88	1.27	1.01
guanidinoacetate	ME293839	0.60	0.91	1.03	1.30
N2-acetyllysine	ME293852	0.70	0.85	1.28	1.14
N-acetylaspartate (NAA)	ME293838	0.78	0.73	1.18	1.25
acetylphosphate	ME293884	1.24	0.88	1.49	0.67
3-hydroxyisobutyrate	ME293846	1.41	0.93	1.18	0.70
salicylate	ME293918	1.37	0.91	1.29	0.67
glycolate (hydroxyacetate)	ME293916	1.62	0.87	1.27	0.56
N-acetylglutamate	ME293841	1.76	0.76	1.27	0.57
3-hydroxybutyrate (BHBA)	ME293902	1.90	0.94	1.23	0.38
3-methylglutarate/2-methylglutarate	ME293894	1.67	0.98	1.41	0.37
quinate	ME293923	1.67	1.16	1.18	0.36
3-hydroxyadipate	ME293893	1.50	1.58	0.93	0.28
glucose	ME293867	1.77	1.46	0.64	0.39
2-hydroxyphenylacetate	ME293858	1.95	1.36	0.62	0.37
arabonate/xylonate	ME293872	1.95	1.30	0.54	0.47
allantoic acid	ME293909	1.64	1.00	0.93	0.66
glycerate	ME293868	1.59	1.11	0.88	0.63
pimelate (C7-DC)	ME293899	1.88	1.18	0.89	0.39
cysteine s-sulfate	ME293854	1.80	1.01	0.90	0.57
ribonate	ME293874	1.85	1.06	0.90	0.50
erythronate	ME293860	1.42	1.48	0.75	0.52
ethylmalonate	ME293849	1.58	1.29	0.60	0.67
methylsuccinate	ME293850	1.55	1.32	0.70	0.59
ribulonate/xylulonate	ME293876	1.67	1.28	0.72	0.54
mannose	ME293866	1.66	1.29	0.84	0.47
sedoheptulose	ME293877	1.71	1.29	0.86	0.43

Factors:

F1	diabetes:db/db \| time of day:ZT17
F2	diabetes:db/db \| time of day:ZT5
F3	diabetes:db/m \| time of day:ZT17
F4	diabetes:db/m \| time of day:ZT5

Data matrix