Clustering data with hclust algorithm for Eicosanoid profiles of dermal fibroblasts (part-II) (Study ST001254)
Reversed phase NEGATIVE ION MODE (Analysis AN002083)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|---|
| 5 HETE | ME293939 | 0.21 | 3.84 | 0.20 | 1.30 | 0.09 | 0.53 | 0.19 | 0.08 |
| PGE1 | ME293929 | 0.26 | 1.09 | 0.31 | 0.28 | 0.12 | 2.54 | 0.29 | 1.85 |
| 6-keto PGF1α | ME293925 | 0.02 | 1.98 | 0.03 | 0.01 | 0.01 | 2.01 | 0.02 | 3.40 |
| PGE2 | ME293927 | 0.22 | 1.62 | 0.24 | 0.22 | 0.12 | 1.92 | 0.24 | 2.89 |
| PGF2α | ME293928 | 0.31 | 1.46 | 0.35 | 0.42 | 0.10 | 1.86 | 0.34 | 2.40 |
| PGA2 | ME293931 | 0.74 | 0.73 | 0.78 | 0.84 | 0.77 | 1.53 | 0.76 | 1.36 |
| 20-HETE | ME293935 | 1.42 | 0.76 | 1.24 | 0.70 | 1.38 | 0.91 | 1.21 | 1.46 |
| Resolvin D1 | ME293930 | 1.09 | 0.54 | 1.08 | 1.04 | 1.06 | 1.06 | 1.07 | 1.09 |
| 12 HETE | ME293937 | 0.16 | 0.02 | 0.18 | 2.45 | 0.09 | 1.17 | 0.17 | 0.04 |
| (±)14(15)-EET | ME293938 | 0.46 | 0.34 | 0.56 | 1.87 | 0.35 | 1.07 | 0.75 | 0.46 |
| 15 HETE | ME293936 | 0.58 | 0.37 | 0.66 | 1.82 | 0.31 | 1.03 | 0.63 | 0.64 |
| TXB2 | ME293926 | 0.20 | 0.12 | 0.21 | 1.92 | 0.13 | 1.69 | 0.22 | 0.22 |
| (±)8,9-DHET | ME293934 | 0.28 | 0.21 | 0.34 | 1.71 | 0.19 | 1.54 | 0.34 | 0.42 |
| (±)11,12-DHET | ME293933 | 0.50 | 0.24 | 0.47 | 1.64 | 0.32 | 1.56 | 0.48 | 0.45 |
| (±)14,15-DHET | ME293932 | 0.44 | 0.28 | 0.42 | 1.59 | 0.35 | 1.62 | 0.41 | 0.49 |
Factors:
| F1 | Genotype:cPLA2α KI | Treatment:Pyrrophenone (50nM) |
| F2 | Genotype:cPLA2α KI | Treatment:Untreated |
| F3 | Genotype:cPLA2α KO | Treatment:CMV control Virus |
| F4 | Genotype:cPLA2α KO | Treatment:cPLA2α KI Virus |
| F5 | Genotype:cPLA2α KO | Treatment:Pyrrophenone (50nM) |
| F6 | Genotype:cPLA2α KO | Treatment:Wild Type Virus |
| F7 | Genotype:Wild Type | Treatment:Pyrrophenone (50nM) |
| F8 | Genotype:Wild Type | Treatment:Untreated |
