Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Metatranscriptomic Analysis of the Mouse Gut Microbiome Response to the Persistent Organic Pollutant 2,3,7,8-Tetrachlorodibenzofuran (Study ST001299)

Reversed phase POSITIVE ION MODE (Analysis AN002163)

Metabolite	Structure	F1	F2	F3
Methionine	ME303965	1.83	1.02	0.15
3-S-Methylthiopropionate	ME303963	2.15	0.52	0.11
Deoxyinosine	ME303916	2.05	0.57	0.17
Pipecolic Acid	ME303953	0.80	2.10	0.10
Asparagine	ME304019	0.71	1.59	0.70
Ornithine	ME304026	0.61	1.78	0.61
dAMP	ME303961	0.62	0.65	1.88
2-Aminooctanoic acid	ME303956	0.64	0.75	1.61
dTMP	ME303993	0.87	0.61	1.62
Maleic acid	ME304014	1.11	0.57	1.32
AMP	ME303987	0.89	0.71	1.41
Deoxyribose-phosphate	ME303997	0.98	0.62	1.39
N-Acetyl-L-ornithine	ME303949	0.69	1.01	1.30
dCMP	ME303972	0.78	0.73	1.48
Glutathione	ME303959	0.75	0.87	1.39
3-Methylphenylacetic acid	ME303955	0.77	0.85	1.38
Ketoleucine	ME303952	0.78	0.85	1.37
Dihydroorotate	ME303989	0.65	1.35	1.00
Fumarate	ME303911	0.62	1.24	1.14
Citrulline	ME303903	1.08	1.35	0.57
Hydroxyproline/Aminolevulinate	ME303927	1.38	0.65	0.97
sn-Glycerol-3-phosphate	ME303995	1.29	0.67	1.03
dGDP	ME303990	1.24	0.76	1.00
Prephenate	ME303979	1.21	0.77	1.02
GMP	ME303980	1.16	0.75	1.10
Hydroxyisocaproic acid	ME304022	1.13	0.78	1.09
4-Pyridoxic acid	ME303930	1.18	0.96	0.86
Quinolinate	ME303931	1.18	0.94	0.88
Indole-3-carboxylic acid	ME303941	1.14	1.00	0.85
Nicotinate	ME303944	1.15	0.97	0.88
Succinate/Methylmalonic acid	ME303942	1.15	0.98	0.87
3-Phospho-serine	ME303929	1.26	0.91	0.80
Glucarate	ME303966	1.22	0.93	0.85
Ile-Asp-Ser (IDS)	ME303922	1.21	0.87	0.90
ATP	ME303999	1.18	0.90	0.90
UDP	ME303948	1.19	0.88	0.91
Aconitate	ME303934	1.27	0.88	0.85
Inosine	ME303962	1.27	0.89	0.85
4-Hydroxyphenyllactate	ME303900	1.30	0.85	0.85
Trehalose-6-Phosphate	ME303958	1.29	0.84	0.84
GDP	ME303950	1.29	0.82	0.89
Cytosine	ME303943	1.25	0.85	0.90
Folate	ME303940	1.24	0.83	0.92
Alpha-ketoglutarate	ME303938	1.26	1.07	0.67
Pyruvate	ME303921	1.24	1.08	0.68
O-Acetyl-serine	ME303907	1.25	1.03	0.72
Acetyl-aspartate	ME303910	1.23	1.00	0.77
Acetyllysine	ME303909	1.21	1.04	0.75
Glucose	ME303947	1.19	1.05	0.76
Orotate	ME303975	1.08	1.19	0.73
Phenylpyruvate	ME303964	1.15	1.04	0.81
Ascorbic acid	ME303906	1.12	1.08	0.79
N-Acetyl-glutamine	ME303937	1.11	1.08	0.81
Adenosine	ME303928	1.02	1.11	0.84
N-Carbamoyl-L-aspartate	ME303985	1.07	1.11	0.82
Ribose	ME303936	1.08	1.13	0.79
Glutamine	ME304020	1.01	0.99	0.99
Asp-Leu/Ile-Ser (DLS)	ME303982	0.96	1.03	1.00
Citraconic acid	ME304024	0.98	1.03	0.99
Thiamine	ME304018	0.87	1.07	1.07
3-Hydroxybutyric acid	ME303924	0.91	1.05	1.04
Phenyllactic acid	ME304001	0.93	1.03	1.04
Malate	ME303996	0.90	1.09	1.00
Histidine	ME304011	0.93	1.07	1.00
Pro-Glu (PE)	ME304016	0.94	1.08	0.98
N-Acetyl-glutamate	ME303988	1.05	1.06	0.89
p-Aminobenzoate	ME303998	1.04	1.02	0.94
Aminoadipic acid	ME303977	1.07	1.01	0.92
Citrate/isocitrate	ME303974	1.08	1.01	0.91
Chlorpropamide	ME303967	1.00	1.05	0.94
Ser-Leu/Ile-Asp (SID)	ME303994	1.01	1.09	0.90
4-Aminobutyrate	ME304004	0.98	1.12	0.90
Glutamate	ME304010	0.98	1.10	0.92
Ser-Asp (SD)	ME304015	0.93	0.94	1.16
Guanine	ME304008	0.98	0.95	1.09
CMP	ME304003	1.01	0.91	1.09
5-Methoxytryptophan	ME303984	1.03	0.91	1.07
Acetoacetate	ME304005	1.02	0.90	1.08
Pyridoxamine	ME304017	1.09	0.87	1.05
UMP	ME303968	1.08	0.88	1.05
Anthranilate	ME303992	1.10	0.87	1.03
Hydroxyphenylacetic acid	ME303978	1.09	0.89	1.02
Oxaloacetate	ME304002	1.07	0.96	0.97
Riboflavin	ME303981	1.06	0.97	0.96
2,3-Dihydroxybenzoic acid	ME304025	1.05	0.92	1.04
Lactate	ME304012	1.07	0.95	0.99
Leu-Asp (LD)	ME304009	1.07	0.93	1.00
Taurine	ME304013	1.07	0.92	1.01
Acetyl-glycine	ME303991	0.98	1.19	0.83
Pyridoxine	ME303954	0.96	1.28	0.76
Pantothenate	ME304027	0.88	1.23	0.88
Threonine/Homoserine	ME304023	0.90	1.20	0.89
Lysine	ME304021	0.92	1.15	0.94
Pyroglutamic acid	ME304028	0.94	1.13	0.94
Asp-Leu-His (DLH)	ME304007	0.90	1.12	0.97
Alanine/Sacrosine	ME304000	0.88	1.15	0.97
Cystathionine	ME304006	0.87	1.17	0.96
Leucine/Isoleucine	ME303951	0.72	1.25	1.03
Aspartate	ME303973	0.82	1.14	1.04
Serine	ME303970	0.79	1.20	1.01
Tryptophan	ME303971	0.79	1.20	1.01
Glycine	ME303976	0.82	1.17	1.01
Proline	ME303983	0.81	1.18	1.01
GTP	ME303986	1.45	NA	0.55
UDP-D-glucose	ME303905	1.43	0.67	0.84
CDP	ME303912	1.37	0.76	0.83
IMP	ME303908	1.42	0.73	0.82
2-Keto-isovalerate	ME303969	1.46	0.92	0.61
2-Isopropylmalic acid	ME303913	1.41	0.89	0.69
Gluconate	ME303904	1.36	0.91	0.73
Trehalose/Sucrose	ME303957	1.33	0.91	0.75
Glucono-_-lactone	ME303902	1.58	0.93	0.49
3-Phosphoglycerate	ME303919	1.69	0.69	0.62
Phosphoenolpyruvate	ME303920	1.63	0.72	0.65
Fructose-1,6-bisphosphate	ME303914	1.49	0.69	0.55
2-Keto-D-gluconate	ME303918	1.54	0.76	0.70
UDP-N-acetyl-glucosamine	ME303901	1.48	0.75	0.65
Ribulose-5-phosphate	ME303946	1.66	0.38	0.94
4-Phosphopantothenate	ME303935	1.55	0.60	0.82
N-Acetyl-glucosamine-1/6-phosphate	ME303917	1.61	0.46	0.92
Dihydroxy-acetone-phosphate	ME303945	1.58	0.54	0.87
Ribose-5-phosphate	ME303933	1.64	0.51	0.86
FMN	ME303926	1.84	0.51	0.59
Fructose-6-phosphate	ME303923	1.88	0.46	0.66
6-Phospho-D-gluconate	ME303915	1.81	0.33	0.78
D-Sedoheptulose-1/7-phosphate	ME303939	1.93	0.32	0.75
Erythrose-4-phosphate	ME303925	2.00	0.36	0.64
Glucose-1/6-phosphate	ME303932	1.98	0.34	0.68

Factors:

F1	Treatment:Control
F2	Treatment:High Dose TCDF
F3	Treatment:Low Dose TCDF

Data matrix