Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Metabolomics Adaptation of Juvenile Pacific Abalone Haliotis discus hannai to Heat Stress (Study ST001324)

HILIC NEGATIVE ION MODE (Analysis AN002203)

Metabolite	Structure	F1	F2	F3	F4	F5
D(-)-beta-hydroxy butyric acid	ME308854	0.64	1.87	1.12	0.87	0.53
Salidroside	ME308971	0.58	2.04	1.07	0.95	0.39
Glycyrrhizic Acid	ME309085	0.21	2.14	1.05	1.38	0.23
Phenacemide	ME309030	0.31	1.61	1.04	1.80	0.26
3-Hydroxydodecanoic acid	ME308964	0.50	2.07	0.41	0.54	1.29
5-methoxytryptophan	ME308920	0.22	2.48	0.18	1.13	0.72
1,3-Dimethyluric acid	ME308891	0.44	0.41	1.16	1.52	1.52
Nicotinamide	ME308878	0.16	0.16	1.03	1.81	1.85
(-)-Naringenin	ME308958	0.24	0.23	1.11	1.46	2.00
Maleamic acid	ME308833	0.31	0.29	1.07	1.53	1.82
O-Acetyl-L-serine	ME308845	0.36	0.27	1.10	1.50	1.81
3^-Hydroxyropivacaine	ME308981	0.91	1.07	0.44	0.98	1.40
1-Palmitoyl-2-linoleoyl-sn-glycero-3-phosphate	ME309083	0.89	1.48	0.08	1.32	0.92
delta-Tocotrienol	ME309054	0.92	1.49	0.19	1.29	0.84
2-Oleoyl-1-stearoyl-sn-glycero-3-phosphoserine	ME309084	1.09	1.18	0.42	1.11	1.01
gamma-Tocopherol	ME309060	1.05	1.27	0.35	1.12	0.99
Arachidic acid	ME309000	0.91	1.10	0.40	1.43	0.96
Palmitic acid	ME309001	0.91	1.30	0.35	1.36	0.86
6-Phospho-D-gluconate	ME308941	1.85	0.82	1.10	0.37	0.89
Aklomide	ME308945	1.78	0.85	1.01	0.57	0.80
3,4-Dihydroxybenzoate (Protocatechuic acid)	ME308862	1.54	0.78	0.46	0.71	1.32
Temazepam	ME309002	1.12	0.51	0.85	0.93	1.53
Sildenafil	ME309062	1.11	0.69	1.09	1.01	1.13
3-Methylphenylacetic acid	ME308858	1.12	0.61	1.11	1.04	1.15
N-Acetylmannosamine	ME308970	1.18	0.59	1.06	1.04	1.16
Alpha-D-Glucose 1,6-bisphosphate	ME309023	1.15	0.71	1.08	0.90	1.19
L-Citrulline	ME308867	1.20	0.63	1.00	0.85	1.31
Uridine 5^-monophosphate (UMP)	ME309013	1.21	0.66	0.98	0.91	1.23
Glucosamine	ME308892	1.09	0.49	1.08	0.93	1.43
Dihydrouracil	ME308838	0.98	0.59	1.05	1.02	1.37
Phenylpyruvate	ME308855	1.00	0.56	1.11	0.96	1.42
2-Oxoadipic acid	ME308909	0.99	0.78	1.20	0.89	1.20
Bestatin	ME309040	0.94	0.62	1.25	0.92	1.35
alpha,alpha-Trehalose	ME309025	0.96	0.72	1.14	0.91	1.31
N-Acetylglucosamine 1-phosphate	ME308988	1.03	0.64	1.17	0.92	1.30
CITIOLONE	ME309003	1.25	1.00	1.18	0.79	0.85
N2-Acetyl-L-ornithine	ME308868	1.53	0.83	1.19	0.72	0.79
Ricinoleic acid	ME309034	1.44	0.46	1.15	0.86	1.14
O-Succinyl-L-homoserine	ME308910	1.50	0.62	1.05	0.79	1.05
2^-O-Methyluridine	ME308965	1.63	0.54	1.04	0.66	1.14
L-Arginine	ME308864	1.61	0.53	1.10	0.72	1.07
Dantrolene	ME308984	1.47	0.70	1.15	0.68	1.06
S-Nitroso-L-glutathione	ME309082	1.36	0.81	1.16	0.68	1.05
Jasmonic acid	ME308934	1.44	0.74	1.09	0.89	0.88
Xylitol	ME308994	1.37	0.78	1.07	0.93	0.87
Suberylglycine	ME308919	1.27	0.71	1.13	0.96	0.97
L-Arabitol	ME308884	1.33	0.61	1.12	0.98	1.01
N1-Methyl-4-pyridone-3-carboxamide	ME308883	1.38	0.63	1.11	0.94	0.98
Butabarbital	ME308904	1.40	0.62	1.10	0.89	1.03
Pentobarbital	ME308917	1.40	0.66	1.14	0.85	1.00
Sinapyl alcohol	ME308902	1.37	0.72	0.93	0.92	1.04
Nicotinamide adenine dinucleotide (NAD)	ME309081	1.35	0.89	0.93	0.87	0.94
Deoxythymidine 5^-phosphate (dTMP)	ME309010	1.34	0.83	1.00	0.75	1.08
O-Phosphotyrosine	ME309008	1.43	0.82	0.94	0.74	1.05
Malonic acid	ME308899	1.62	0.54	1.09	0.36	1.43
D-Fructose	ME309035	1.25	0.52	1.07	0.64	1.55
3-methylcytidine	ME308983	1.23	0.78	1.06	0.68	1.27
D-glucosamine 6-phosphate	ME308968	1.45	0.54	1.09	0.64	1.31
D-Quinovose	ME308876	1.40	0.64	1.08	0.64	1.27
Adenylsuccinic acid	ME309064	0.56	1.22	0.86	1.64	0.66
Silybin	ME309065	0.58	1.12	0.95	1.59	0.75
2-Deoxyribose 5-phosphate	ME308959	0.56	0.99	1.09	1.45	0.94
Fluorouracil	ME308837	0.65	1.03	1.02	1.48	0.83
Stavudine	ME308949	0.69	1.07	1.00	1.48	0.76
2-Dehydro-3-deoxy-D-gluconate	ME308922	0.69	1.19	0.95	1.42	0.74
3-Acetyl-11-keto-.beta.-boswellic acid	ME309071	0.81	1.15	0.85	1.43	0.71
5^-Phosphoribosyl-5-amino-4-imidazolecarboxamide (AICAR)	ME309021	0.70	1.20	1.05	1.48	0.58
Hesperetin	ME309037	0.79	1.01	1.07	1.55	0.60
1,7-Dimethylxanthine	ME308874	0.44	0.90	1.20	1.91	0.63
3^-O-methyladenosine	ME308991	0.53	1.02	1.13	1.77	0.60
Uridine	ME308993	0.57	1.01	1.10	1.69	0.65
Acamprosate	ME308877	0.52	0.75	1.17	1.57	1.05
Theobromine	ME308896	0.58	0.76	1.08	1.60	1.01
5-Hydroxyindoleacetate	ME308885	0.46	0.90	1.21	1.61	0.89
Quinate	ME308886	0.55	0.92	1.22	1.56	0.82
3-Indolepropionic acid	ME308935	0.79	0.83	1.23	1.54	0.68
Ketanserin	ME309061	1.02	0.79	1.08	1.39	0.75
Ammelide	ME308844	0.72	0.67	0.88	1.64	1.06
Gamma-Glutamylcysteine	ME308936	0.89	0.87	0.77	1.66	0.74
L-Galactono-1,4-lactone	ME308870	0.81	0.86	0.89	1.57	0.84
3-Methyluridine	ME308961	1.14	1.28	1.12	0.79	0.70
Cytidine 2^,3^-cyclic phosphate	ME308996	1.23	1.46	0.85	0.64	0.76
Nomilin	ME309068	1.15	1.44	1.01	0.70	0.70
5(S)-HETE	ME309033	0.80	1.32	0.84	0.87	1.12
Allantoin	ME308866	0.90	1.36	0.64	0.93	1.04
Bufexamac	ME308948	0.97	1.03	0.60	1.32	0.94
Aristolochic Acid	ME309024	0.91	1.08	0.67	1.40	0.84
Hexadecanedioic acid	ME309015	0.89	0.99	0.67	1.44	0.90
Acetylvalerenolic acid	ME308960	0.79	1.12	0.78	1.35	0.90
Cortisol 21-acetate	ME309055	0.80	1.14	0.69	1.25	1.02
(4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,1 6,19-Docosahexaenoic acid	ME309017	0.92	1.10	0.82	1.21	0.89
Abscisic Acid (cis,trans)	ME308979	0.93	1.11	0.82	1.07	1.01
5,6,7,8-tetrahydro-2-Naphthoic Acid	ME309029	1.02	1.23	0.80	1.07	0.81
Pentadecanoic Acid	ME308989	0.96	1.24	0.63	1.17	0.88
Dethiobiotin	ME308906	0.82	0.94	1.57	0.93	0.92
Flavin mononucleotide (FMN)	ME309067	1.00	1.09	1.34	0.89	0.79
Salicylic acid	ME308852	0.80	1.19	1.23	0.88	0.96
2^-Deoxy-D-ribose	ME308956	1.23	0.73	0.86	1.20	0.94
Clozapine	ME309048	1.16	0.78	0.75	1.17	1.05
Repaglinide	ME309070	1.04	0.89	0.75	1.14	1.10
Maltitol	ME309036	0.81	1.09	1.25	1.17	0.77
Scopoletin	ME308901	0.82	1.11	1.27	1.18	0.72
Evodiamine	ME309079	0.80	1.08	1.11	1.38	0.67
Statil	ME309050	0.74	1.03	1.24	1.37	0.71
Glycerophosphocholine	ME308942	0.67	1.17	1.10	1.15	0.95
Fructose 1-phosphate	ME308946	0.90	1.13	0.94	1.21	0.79
Cytidine 5^-diphosphocholine (CDP-choline)	ME309066	0.92	1.18	1.00	1.13	0.78
D-Arabinono-1,4-lactone	ME308985	0.84	1.16	1.03	1.17	0.81
L-homocysteic acid	ME308880	0.90	1.08	1.03	1.15	0.85
Salicylamide	ME308841	0.87	1.10	1.07	1.13	0.86
2-keto-D-Gluconic acid	ME308938	0.90	1.13	1.11	1.15	0.74
Nicotinuric acid	ME308893	0.83	1.09	1.13	1.18	0.82
trans-cinnamate	ME308900	0.88	1.07	1.11	1.21	0.78
Sulfanilamide	ME308850	0.94	1.15	1.05	1.05	0.82
Tetrahydrobiopterin	ME308925	0.91	1.18	1.02	1.01	0.88
N-Acetyl-L-alanine	ME308860	0.85	1.08	1.10	1.09	0.91
Oxoadipic acid	ME309007	0.84	1.10	1.07	1.04	0.98
Ethosuximide	ME308972	0.83	1.14	1.10	1.02	0.94
N-Acetyl-D-Glucosamine 6-Phosphate	ME309005	0.79	1.13	1.10	1.05	0.96
2-Thiocytidine	ME308969	0.89	0.99	1.10	1.20	0.86
Salsalate	ME308943	0.90	0.97	1.17	1.23	0.79
Deoxyguanosine	ME308974	1.06	0.85	1.16	1.14	0.85
Furegrelate	ME309069	1.01	0.91	1.10	1.20	0.81
gamma-L-Glutamyl-L-phenylalanine	ME308963	1.03	0.97	1.08	1.17	0.78
1,2-Diacetylhydrazine	ME308869	0.91	0.80	1.07	1.18	1.06
Orotate	ME308998	0.96	0.84	0.99	1.18	1.02
Phenylpropionylglycine	ME308954	0.93	0.85	0.97	1.18	1.06
3^-O-methylguanosine	ME309006	0.92	0.80	1.17	1.20	0.96
Uracil	ME308839	0.82	0.88	1.08	1.24	1.00
Naringin	ME309078	0.86	0.90	1.17	1.14	0.98
D-Ribose 1,5-bisphosphate	ME309019	0.87	0.97	1.04	1.16	0.98
Thiamine	ME308933	0.87	0.93	1.09	1.13	1.01
Fludrocortisone acetate	ME309056	0.75	0.98	0.93	1.39	0.93
Sulfamethizole	ME308957	0.81	0.90	1.04	1.38	0.88
Dopamine	ME308861	0.80	1.02	0.90	1.24	1.00
1-Palmitoyl Lysophosphatidic Acid	ME309052	0.77	1.06	1.10	1.21	0.90
5^-CMP	ME309044	0.80	0.98	1.07	1.26	0.93
Leukotriene C4	ME309080	0.84	1.01	0.97	1.26	0.91
D-Glucosamine 1-phosphate (Glucosamine-1P)	ME308962	0.80	1.08	1.00	1.24	0.87
Ethynodiol diacetate	ME309039	0.85	1.07	0.98	1.25	0.85
3^-O-Methylinosine	ME308992	0.84	1.04	0.99	1.18	0.94
S-Methyl-5^-thioadenosine	ME309032	0.90	0.96	0.99	1.20	0.94
5^-O-methylthymidine	ME308923	0.76	1.00	0.97	1.05	1.20
L-Cysteine	ME308840	0.72	1.01	0.99	1.15	1.13
Guanidoacetic acid	ME308921	0.89	0.84	1.09	1.09	1.12
3-Hydroxycapric acid	ME308903	0.94	0.82	1.06	0.97	1.24
N1-Methyl-2-pyridone-5-carboxamide	ME308848	0.88	0.80	1.07	1.04	1.23
hydrocortisone 21-acetate	ME309059	1.10	0.93	0.84	0.93	1.16
Taurocholate	ME309072	1.07	1.03	0.82	0.95	1.07
Deoxyinosine	ME308937	1.07	0.90	0.97	0.78	1.27
D-Mannitol 1-phosphate	ME309011	0.91	0.93	0.92	0.90	1.31
Adynerin	ME309073	1.11	0.95	0.85	1.09	0.95
Inosine	ME308955	1.20	0.90	0.95	1.05	0.88
Pravastatin	ME309058	1.16	0.94	0.98	1.12	0.79
1-Deoxy-D-xylulose 5-phosphate	ME308905	1.16	1.12	0.93	0.81	0.96
3-Aminopropanesulphonic Acid	ME308895	1.31	1.06	0.91	0.90	0.80
Quetiapine	ME309045	1.21	1.04	0.89	0.97	0.85
Hieracin	ME308990	1.00	0.86	1.30	0.93	1.01
2-Deoxy-D-glucose 6-phosphate	ME308931	1.12	0.87	1.11	0.79	1.15
Pyrethrosin	ME309027	1.13	0.82	1.09	0.82	1.17
N4-Acetylcytidine	ME308976	1.17	0.83	1.05	0.87	1.10
L-Aspartyl-L-phenylalanine	ME308967	1.10	0.88	1.06	0.89	1.08
L-Fucose 1-phosphate	ME308928	1.11	0.88	1.07	0.92	1.05
Acyclovir	ME308975	1.12	0.80	1.04	0.95	1.10
Nicotinamide ribotide	ME309041	1.08	0.87	0.98	0.97	1.09
Guanosine	ME309026	1.21	0.79	1.11	0.89	1.04
L-Cystine	ME308987	1.23	0.80	1.03	0.91	1.04
5(S),14(R)-Lipoxin B4	ME309053	1.19	0.91	1.03	0.86	1.02
Ribothymidine	ME308944	1.23	0.87	1.11	0.88	0.95
dTMP	ME309022	1.11	0.98	1.17	0.87	0.93
Xanthine	ME308847	1.10	1.01	1.06	0.86	0.98
D-Glucuronate	ME309049	1.01	1.11	0.97	0.99	0.90
MK 571	ME309076	1.08	1.05	1.00	0.94	0.92
Prunasin	ME308999	1.08	1.06	0.99	0.95	0.92
2^-Deoxyguanosine 5^-monophosphate (dGMP)	ME309028	1.07	1.07	1.07	0.95	0.87
L-Fucose-1-phosphate	ME308914	1.08	1.09	1.08	0.95	0.83
Uric acid	ME308859	0.97	1.11	1.05	0.97	0.91
Vanylglycol	ME308911	0.99	1.10	1.10	0.94	0.90
2^-Deoxyuridine	ME308980	1.03	0.91	0.94	1.12	0.97
N-carbamoyl-L-aspartate	ME308889	1.03	0.89	1.02	1.08	0.99
Lecanoric acid	ME309004	1.08	0.91	1.02	1.02	0.99
Perseitol	ME309057	1.06	0.93	0.98	1.03	0.99
L-dihydroorotate	ME308865	1.01	0.89	1.11	0.97	1.06
5-Oxo-ETE	ME309031	1.02	0.89	1.03	1.00	1.07
N-Acetylneuraminic acid	ME309016	1.03	0.89	1.04	0.98	1.07
gamma-L-Glutamyl-L-glutamic acid	ME309020	1.08	0.82	1.12	1.02	1.00
Cytidine 5^-monophosphate (CMP)	ME309014	1.05	0.79	1.08	1.09	1.03
Pyridoxal (Vitamin B6)	ME308857	1.09	0.79	1.02	1.03	1.07
S-Adenosyl-L-homocysteine	ME309047	1.03	0.82	1.04	1.04	1.08
D-Mannose-6-phosphate	ME308947	0.95	0.96	1.15	0.94	1.05
Nicotinate	ME308834	1.05	0.94	1.10	0.99	0.95
Oxazepam	ME309012	1.08	0.93	1.10	0.98	0.95
Acetyl phosphate	ME308842	0.92	1.04	1.09	1.05	0.94
3-Phosphoserine	ME308930	0.92	1.02	1.06	1.03	0.98
alpha-Guanidinoglutaric Acid	ME308882	0.91	0.99	1.07	1.03	1.02
Mevalonic acid	ME308986	0.98	0.95	1.04	1.03	1.02
N-Acetylaspartylglutamate (NAAG)	ME309009	0.98	0.93	1.06	1.05	1.00
Taurine	ME308835	0.98	1.00	1.07	1.03	0.94
3-Hydroxyisovaleric acid	ME308851	0.97	0.94	1.12	1.04	0.98
IS	ME308894	1.00	0.96	1.09	1.00	0.97
D-Glucarate	ME308916	0.92	1.10	1.05	0.93	1.02
N-Acetyl-L-Histidine	ME308907	0.93	1.06	1.17	0.97	0.93
Azacitidine	ME308929	1.10	1.34	0.53	1.39	0.49
12-Oxo-2,3-dinor-10,15-phytodienoic acid	ME309075	0.77	1.40	0.73	1.46	0.54
Estradiol Cypionate	ME309051	0.61	1.48	0.59	1.50	0.69
5,2^-O-dimethyluridine	ME308982	0.52	1.29	1.22	1.54	0.51
Hexanoylglycine	ME308890	0.46	1.31	1.11	1.58	0.59
Acetylcarnitine	ME308924	0.74	1.50	1.07	1.19	0.51
Floxuridine	ME308973	0.66	1.53	1.10	1.16	0.59
Betaine aldehyde	ME308897	0.67	1.53	0.89	1.38	0.50
N-Acetyl-D-lactosamine	ME309046	0.62	1.44	0.92	1.42	0.56
Thymine	ME308836	0.64	1.42	1.10	1.36	0.51
Xanthosine	ME308951	0.64	1.43	1.13	1.32	0.52
Enalaprilat	ME309018	0.58	1.45	1.10	1.35	0.56
L-Tyrosine	ME308875	0.58	1.47	1.10	1.30	0.59
Acadesine (Drug)	ME308966	0.63	1.30	1.18	1.42	0.53
D-Glucose 6-phosphate	ME308926	0.61	1.37	1.05	1.46	0.52
(R)-mevalonic acid 5-Phosphate	ME308953	0.71	1.73	0.95	0.99	0.60
Cyclohexylsulfamate	ME308872	0.67	1.58	0.81	1.12	0.76
DL-Vanillylmandelic acid	ME308908	0.79	1.55	0.89	1.07	0.66
APIIN	ME309077	0.85	1.38	0.95	1.04	0.76
D-Biotin	ME308952	0.86	1.33	0.99	1.04	0.78
Phenethyl Caffeiate	ME308997	0.93	1.28	0.99	1.05	0.75
L-Methionine	ME308846	0.89	1.27	0.97	1.13	0.73
Pioglitazone	ME309042	0.91	1.31	0.94	1.10	0.72
O-Phospho-L-threonine	ME308873	0.84	1.47	1.00	0.92	0.77
L-Glutamine	ME308879	1.00	1.38	1.00	0.95	0.68
Glycerol 3-phosphate	ME308849	1.00	1.29	0.99	0.92	0.80
Sedoheptulose	ME308887	0.93	1.39	1.02	0.91	0.75
Vindoline	ME309063	0.93	1.36	0.95	0.94	0.81
Pyridoxal 5^-phosphate	ME308950	0.90	1.39	1.18	0.94	0.65
S-Allyl-L-cysteine	ME308853	0.88	1.37	1.17	1.01	0.63
L-Arabinono-1,4-lactone	ME308881	0.88	1.19	1.18	1.06	0.75
Kaempferol	ME308978	0.97	1.24	1.06	1.06	0.69
(+-)-Taxifolin	ME308977	1.00	1.25	1.16	0.95	0.68
Glycocholic acid	ME309074	1.02	1.15	0.97	1.21	0.65
L-Iditol	ME309038	0.85	1.20	1.07	1.30	0.61
Primidone	ME308939	0.81	1.34	1.11	1.16	0.61
5-Aminoimidazole-4-carboxamide	ME308843	0.66	1.34	1.02	1.26	0.73
N-Acetylaspartate	ME308888	0.68	1.21	1.07	1.32	0.74
Arachidonic Acid (peroxide free)	ME308995	0.73	1.36	0.88	1.28	0.71
Rosiglitazone	ME309043	0.81	1.29	0.94	1.23	0.71
Thymidine	ME308927	0.89	1.26	0.92	1.22	0.68
L-Gulonic gamma-lactone	ME308871	0.66	0.50	1.21	0.89	1.81
Cytosine	ME308863	0.28	0.85	1.12	1.26	1.54
Amrinone	ME308898	0.70	0.45	1.19	1.30	1.42
3,4-Methylenedioxymethamphetamine (MDMA)	ME308918	0.67	0.64	1.04	1.39	1.28
Tiopronin	ME308913	0.91	0.55	1.13	1.14	1.31
7-Methylxanthine	ME308915	0.84	0.59	1.06	1.27	1.25
L-Phenylalanine	ME308856	0.84	0.61	1.02	1.28	1.25
N-Acetyl-D-glucosamine	ME308912	0.56	0.64	1.31	1.33	1.26
Dihydrothymine	ME308940	0.80	0.68	1.19	1.37	1.02
N-Acetyl-L-phenylalanine	ME308932	0.70	0.81	1.14	1.29	1.10

Factors:

F1	Acclimatization temperature:10°C \| Heat exposure:-
F2	Acclimatization temperature:30°C \| Heat exposure:-
F3	Acclimatization temperature:- \| Heat exposure:-
F4	Acclimatization temperature:- \| Heat exposure:group H exposure to 31°C for 3hours
F5	Acclimatization temperature:- \| Heat exposure:group L exposure to 31°C for 3hours

Data matrix