Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Stirred suspension bioreactors maintain naïve pluripotency of human pluripotent stem cells (hPSCs) (Study ST001377)

Reversed phase NEGATIVE ION MODE (Analysis AN002297)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8
Thymine	ME317143	2.28	2.18	0.89	0.98	0.02	0.03	2.32	0.01
Fumarate	ME317138	0.74	0.84	0.80	0.65	0.84	0.74	0.90	2.39
Succinate	ME317140	0.65	0.60	0.57	0.60	0.83	1.49	0.72	2.18
MALEAMATE	ME317135	0.12	0.18	NA	0.11	0.22	1.46	1.62	0.05
lactate	ME317132	1.17	1.05	0.43	0.44	0.28	2.25	2.11	0.00
N-ACETYL-L-ASPARTIC ACID	ME317164	1.03	0.36	0.24	0.31	0.10	2.09	2.41	0.09
Sedoheptulose bisphosphate	ME317175	1.28	1.14	1.13	1.09	1.06	0.86	NA	0.01
3-Methyl-2-oxobutanoic acid	ME317137	1.44	1.29	0.82	0.71	0.64	1.30	1.56	0.53
malate	ME317151	1.26	1.16	0.80	0.69	0.60	1.70	1.39	0.47
5-Oxoproline	ME317145	1.19	1.16	0.72	0.72	0.67	1.92	1.54	0.03
L-Glutamate	ME317156	1.07	1.08	0.70	0.71	0.71	1.54	1.20	NA
O-Phospho-L-serine	ME317168	1.02	1.12	0.71	0.76	0.82	1.31	1.29	NA
4-HYDROXYBENZALDEHYDE	ME317142	0.99	0.97	1.05	1.05	1.05	0.91	0.98	0.98
citrate	ME317169	1.01	0.72	1.05	0.93	0.88	1.08	1.21	0.89
Pyroglutamic acid	ME317144	1.09	1.47	0.91	0.90	0.91	1.09	1.58	0.28
L-Asparagine	ME317148	1.10	1.02	1.05	1.04	1.15	1.24	1.19	0.01
L-PROLINE	ME317136	1.21	1.01	1.04	1.06	1.04	1.20	1.42	0.01
Aspartate	ME317150	1.30	1.27	1.03	0.97	0.99	0.58	1.56	0.01
deoxyuridine	ME317171	1.20	1.17	1.11	1.02	1.00	0.64	1.28	0.00
Hypoxanthine	ME317152	1.06	1.33	1.03	1.10	1.06	0.54	1.08	NA
L-Glutamine	ME317154	1.06	1.07	1.07	1.13	1.03	0.74	1.00	NA
L-ORNITHINE	ME317149	1.10	1.16	0.97	1.10	1.11	0.91	1.17	0.03
DEOXYCYTIDINE	ME317170	0.69	0.67	0.96	1.15	1.39	1.25	0.10	0.18
Citraconic acid	ME317146	0.74	0.74	0.85	0.97	1.55	1.47	0.79	0.66
L-LYSINE	ME317155	0.65	0.55	0.92	1.14	1.67	1.17	0.58	NA
Cystine	ME317172	0.92	0.79	1.02	1.10	1.28	0.82	0.98	NA
folate	ME317176	1.03	0.69	0.98	1.09	1.32	1.01	0.81	NA
L-HISTIDINE	ME317160	0.86	0.73	0.92	0.91	1.11	1.43	0.96	0.01
L-Phenylalanine	ME317162	0.77	0.69	0.97	1.10	1.51	1.54	0.89	0.00
L-Leucine	ME317147	0.77	0.70	1.03	1.21	1.62	1.53	0.81	0.00
L-Valine	ME317139	0.69	0.77	1.03	1.22	1.59	1.51	0.85	0.00
Pyruvate	ME317130	1.00	0.86	1.07	1.18	1.51	1.23	0.98	0.09
3-HYDROXY-3-METHYLGLUTARATE	ME317161	0.93	0.80	1.08	1.20	1.63	1.40	0.82	0.00
Acetoacetate	ME317133	0.93	0.81	1.13	1.20	1.58	1.34	0.86	0.00
L-METHIONINE	ME317158	0.64	0.62	0.88	0.98	1.25	1.47	0.74	NA
L-Threonine	ME317141	0.62	0.60	0.90	1.07	1.45	1.30	0.69	NA
thymidine	ME317173	0.59	0.86	0.97	1.07	1.26	1.30	0.98	0.05
aminoimidazole carboxamide ribonucleotide	ME317174	0.74	0.80	0.93	1.11	1.35	1.16	0.89	0.01
ALPHA-D-GLUCOSE	ME317166	0.77	0.84	1.01	1.16	1.37	1.22	0.83	0.00
D-Ribose	ME317159	0.83	0.80	0.96	1.16	1.41	1.25	0.81	0.01
L-Serine	ME317134	0.73	0.73	0.91	1.10	1.43	1.10	0.77	NA
L-Tyrosine	ME317167	0.76	0.67	0.91	1.10	1.40	1.27	0.82	0.00
arginine	ME317163	0.88	0.85	1.02	1.07	1.28	1.12	0.86	0.01
D-Glucono-1-5-lactone	ME317165	0.80	0.89	0.86	1.09	1.26	1.05	0.93	NA
a-ketoglutarate	ME317153	0.26	0.11	0.54	0.89	1.65	3.31	0.12	0.10
CITRAMALATE	ME317157	0.17	0.12	0.88	1.24	2.22	2.20	0.17	0.12
L-Alanine	ME317131	0.38	0.31	0.81	1.17	2.01	2.13	0.48	0.01

Factors:

F1	Cell line:H1 \| Status:day 1
F2	Cell line:H1 \| Status:day 2
F3	Cell line:H1 \| Status:day 3
F4	Cell line:H1 \| Status:day 4
F5	Cell line:H1 \| Status:day 5
F6	Cell line:H9 \| Status:naive
F7	Cell line:H9 \| Status:primed
F8	Cell line:none \| Status:none

Data matrix