Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Activation of ectopic olfactory receptor 544 induces GLP-1 secretion, alters gut microbiome, and improves intestinal permeability. (Study ST001399)

GC POSITIVE ION MODE (Analysis AN002339)

Metabolite	Structure	F1	F2	F3	F4
glutamate	ME320546	2.70	1.09	0.07	0.15
uric acid	ME320599	2.45	1.29	0.10	0.20
serine	ME320584	0.75	2.50	0.37	0.57
2-(4-hydroxyphenyl)ethanol	ME320524	1.99	1.47	0.30	0.30
succinate	ME320588	2.23	1.79	0.02	0.05
L-homoserine	ME320558	1.98	2.12	0.02	0.02
ornithine	ME320574	1.99	1.95	0.06	0.12
fucose	ME320542	1.81	1.70	0.27	0.31
aspartate	ME320532	1.73	1.86	0.22	0.31
palmitoleic acid	ME320577	1.71	1.79	0.33	0.27
glycerate	ME320547	1.47	2.08	0.25	0.34
glycolate	ME320550	1.66	2.16	0.14	0.18
oxoproline	ME320575	1.74	1.97	0.13	0.28
threonine	ME320592	0.92	1.89	0.45	0.85
dihydroxyacetone	ME320539	1.29	1.92	0.57	0.33
fumarate	ME320544	1.51	1.58	0.34	0.64
nonanoic acid	ME320570	1.40	1.49	0.54	0.62
glycerol	ME320548	1.30	1.29	0.78	0.66
2-ketoadipate	ME320526	1.18	1.58	0.83	0.49
methionine sulfoxide	ME320566	1.13	1.62	0.64	0.69
sucrose	ME320589	0.00	0.00	3.60	0.28
tagatose	ME320590	0.00	0.00	2.76	1.11
urea	ME320598	0.82	1.12	1.85	0.23
azelaic acid	ME320533	0.30	0.91	0.10	2.67
cellobiose	ME320534	0.37	0.05	0.40	3.06
2-ketoisocaproic acid	ME320527	0.11	0.11	1.07	2.60
phenylacetate	ME320579	0.00	0.00	1.28	2.59
lyxose	ME320563	0.00	0.00	2.34	1.54
methylamine	ME320567	0.00	0.00	2.19	1.69
xylose	ME320603	0.20	0.15	1.86	1.68
mannose	ME320564	0.08	0.08	1.93	1.79
linoleic acid	ME320560	0.00	0.00	1.96	1.92
squalene	ME320586	0.00	0.00	1.94	1.93
linolenic acid	ME320561	0.00	0.00	2.02	1.86
palmitic acid	ME320576	0.00	0.00	2.09	1.78
xanthurenic acid	ME320602	0.00	0.00	2.07	1.81
O-phosphorylethanolamine	ME320573	0.16	0.18	1.44	2.11
pentadecanoic acid	ME320578	0.29	0.23	1.45	1.93
methionine	ME320565	0.00	0.00	1.59	2.29
thymine	ME320594	0.00	0.00	1.67	2.21
uridine	ME320600	0.00	0.00	1.64	2.24
glycerol-1-phosphate	ME320549	0.00	0.00	1.79	2.09
γ-aminobutyrate	ME320605	0.00	0.00	1.85	2.02
DL-3-aminoisobutyrate	ME320540	0.51	0.36	1.12	1.93
inosine	ME320555	0.58	0.54	1.16	1.66
taurine	ME320591	0.51	0.48	1.18	1.77
arachidic acid	ME320531	0.50	0.63	1.30	1.53
hypoxanthine	ME320554	0.43	0.59	1.34	1.58
glucose	ME320545	0.55	0.50	1.50	1.39
myristic acid	ME320569	0.53	0.47	1.46	1.47
5-aminovalerate	ME320528	0.65	0.47	1.32	1.50
lignoceric acid	ME320559	0.51	0.44	1.37	1.61
deoxycholic acid	ME320538	0.39	0.35	1.66	1.52
stearic acid	ME320587	0.36	0.26	1.77	1.51
phytol	ME320583	0.51	0.29	1.49	1.62
oleic acid	ME320572	0.27	0.43	1.60	1.63
heptadecanoic acid	ME320553	0.30	0.36	1.54	1.71
β-alanine	ME320604	0.40	0.36	1.51	1.65
1-monopalmitin	ME320523	0.89	0.67	1.23	1.17
adenosine	ME320529	0.77	0.70	1.22	1.28
decanoic acid	ME320537	0.72	0.71	1.32	1.21
guanosine	ME320552	0.82	0.53	1.15	1.44
fuculose	ME320543	0.71	0.63	1.15	1.46
leucine	ME320557	0.70	0.71	1.09	1.46
2-hydroxyvalerate	ME320525	0.61	1.08	1.00	1.31
guanine	ME320551	0.66	1.04	1.14	1.16
threose	ME320593	0.85	1.01	1.06	1.09
isoleucine	ME320556	0.77	0.90	1.06	1.25
uracil	ME320597	0.83	0.89	0.98	1.28
phosphogluconate	ME320582	0.98	0.75	0.98	1.26
chenodeoxycholic acid	ME320535	1.02	0.75	0.89	1.31
ursodeoxycholic acid	ME320601	1.01	0.67	0.95	1.33
cholic acid	ME320536	1.06	0.96	0.74	1.24
dodecanoic acid	ME320541	1.03	1.02	0.89	1.07
tyrosine	ME320596	0.69	1.32	0.75	1.28
alanine	ME320530	0.52	0.80	1.07	1.59
lysine	ME320562	0.39	1.25	0.92	1.47
phenylalanine	ME320580	0.43	1.06	1.00	1.52
spermidine	ME320585	0.92	0.72	0.60	1.73
trehalose	ME320595	1.28	1.05	0.12	1.57
norvaline	ME320571	1.84	0.90	0.21	1.04
myo-inositol	ME320568	1.28	0.83	0.83	1.04
phosphate	ME320581	1.42	0.96	0.72	0.89

Factors:

F1	Genotype:Olfr544 KO mouse \| Treatment:HFD
F2	Genotype:Olfr544 KO mouse \| Treatment:HFD + Azelaic acid 0.05 % (w/w)
F3	Genotype:WT mouse \| Treatment:HFD
F4	Genotype:WT mouse \| Treatment:HFD + Azelaic acid 0.05 % (w/w)

Data matrix