Clustering data with hclust algorithm for Steady-state metabolomics time course of Saccharomyces cerevisiae mitochondrial fatty acid synthesis (mtFAS) mutants (Study ST001401)
GC POSITIVE ION MODE (Analysis AN002343)Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methyl beta-D-galactoside | ME321382 | 0.14 | 0.08 | 0.10 | 0.05 | 0.04 | 0.14 | 0.06 | 0.11 | 0.10 | NA | 0.01 | 17.06 | 0.19 | 0.58 | 0.15 | 0.38 | 0.23 |
1-Steroylglycerol | ME321341 | 0.61 | 0.51 | 0.98 | 0.66 | 0.48 | 0.87 | 0.48 | 0.95 | 0.84 | 0.61 | 0.34 | 7.72 | 1.27 | 0.67 | 1.15 | 1.18 | 0.72 |
Allantoin | ME321358 | 1.64 | 0.36 | 0.61 | 0.35 | 0.37 | 0.95 | 0.27 | 0.62 | 0.43 | 0.15 | 0.04 | 8.95 | 0.96 | 0.18 | 0.87 | 0.28 | 0.21 |
Glutamine | ME321300 | 0.31 | 0.07 | 0.26 | 0.29 | 0.64 | 0.30 | 0.05 | 0.19 | 0.26 | 1.29 | 0.00 | 0.26 | 0.59 | 0.35 | 0.55 | 3.47 | 6.77 |
Thymine | ME321352 | 0.41 | 0.93 | 0.31 | 5.93 | 0.44 | 0.74 | 0.79 | 0.22 | 1.16 | 0.47 | 0.05 | 0.78 | 0.68 | 1.20 | 0.47 | 0.66 | 0.51 |
Glucose | ME321274 | 3.00 | 0.02 | 0.02 | 0.00 | 0.00 | 3.30 | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 2.31 | 6.95 | 0.01 | 0.01 | 0.01 | 0.01 |
L-Gulonic acid gamma-lactone | ME321381 | 2.96 | 0.28 | 0.16 | 0.03 | 0.03 | 3.19 | 0.10 | 0.09 | 0.04 | 0.01 | 0.00 | 3.74 | 5.68 | 0.09 | 0.07 | 0.06 | 0.08 |
Vitamin C | ME321357 | 2.35 | 0.05 | 0.04 | 0.01 | 0.01 | 2.95 | 0.02 | 0.01 | 0.02 | 0.01 | 0.00 | 2.39 | 5.30 | 0.02 | 0.01 | 0.02 | 0.04 |
Fructose 1,6-bisphosphate | ME321277 | 2.24 | 0.38 | 0.61 | 0.10 | 0.10 | 5.12 | 0.23 | 0.39 | 0.12 | 0.06 | 0.00 | 0.85 | 2.61 | 0.57 | 0.53 | 0.20 | 0.71 |
Inosine | ME321350 | 1.43 | 0.52 | 0.72 | 0.31 | 0.27 | 4.32 | 0.47 | 0.45 | 0.33 | 0.44 | 0.05 | 1.46 | 3.51 | 0.41 | 0.58 | 0.50 | 0.67 |
Asparagine | ME321299 | 2.44 | 0.15 | 0.20 | 0.11 | 0.18 | 1.79 | 0.20 | 0.11 | 0.16 | 0.20 | 0.04 | 1.70 | 3.70 | 0.18 | 0.04 | 0.19 | 0.40 |
Phosphatidyl Glycerol | ME321389 | 3.18 | 0.02 | 0.03 | 0.02 | 0.01 | 3.37 | 0.01 | 0.02 | 0.03 | 0.01 | 0.01 | 1.13 | 3.73 | 0.02 | 0.03 | 0.02 | 0.04 |
Trehalose | ME321393 | 0.33 | 0.03 | 5.36 | 0.03 | 0.04 | 0.06 | 0.01 | 3.62 | 0.05 | 0.05 | NA | 0.04 | 0.17 | 0.03 | 3.03 | 0.06 | 0.13 |
Turanose | ME321394 | 1.66 | 0.03 | 5.22 | 0.04 | 0.03 | 0.91 | 0.09 | 3.57 | 0.07 | 0.07 | 0.00 | 0.50 | 1.12 | 0.07 | 2.81 | 0.16 | 0.21 |
2-Hydroxyglutaric acid | ME321359 | 3.09 | 0.07 | 2.46 | 0.24 | 0.52 | 3.35 | 0.04 | 2.40 | 0.22 | 0.62 | 0.01 | 0.98 | 0.59 | 0.01 | 0.55 | 0.08 | 0.27 |
D-Malic acid | ME321287 | 2.15 | 0.17 | 3.45 | 0.37 | 0.75 | 1.82 | 0.09 | 3.31 | 0.34 | 0.88 | 0.00 | 0.62 | 0.32 | 0.03 | 1.08 | 0.15 | 0.63 |
Fumaric acid | ME321286 | 2.05 | 0.32 | 2.78 | 0.50 | 0.84 | 1.90 | 0.24 | 2.78 | 0.54 | 0.97 | 0.15 | 0.80 | 0.34 | 0.16 | 1.09 | 0.34 | 0.69 |
Ergosterol | ME321373 | 1.16 | 0.21 | 1.10 | 1.33 | 0.52 | 2.02 | 0.38 | 0.63 | 0.44 | 0.67 | 0.00 | 4.65 | 2.73 | 0.76 | 0.68 | 0.50 | 0.32 |
MG(14:0) | ME321337 | 0.92 | 0.58 | 1.13 | 0.85 | 0.64 | 1.12 | 0.56 | 1.14 | 1.01 | 0.83 | 0.33 | 3.34 | 1.21 | 0.69 | 1.28 | 1.43 | 0.82 |
MG(16:0/0:0/0:0) | ME321339 | 0.50 | 0.62 | 1.08 | 0.85 | 0.65 | 0.56 | 0.50 | 1.09 | 1.08 | 0.87 | 0.32 | 4.25 | 1.23 | 0.66 | 1.63 | 1.63 | 0.89 |
Margaric acid | ME321336 | 0.22 | 0.79 | NA | 0.44 | 0.61 | 0.77 | NA | 1.68 | NA | 0.32 | NA | NA | 1.86 | NA | 0.31 | NA | 1.12 |
Lanosterol | ME321379 | 0.60 | 0.23 | 1.12 | 0.45 | 0.23 | 0.68 | 0.23 | 1.49 | 0.47 | 0.26 | 0.03 | 1.83 | 3.72 | 0.88 | 2.12 | 1.34 | 0.67 |
Putrescine | ME321362 | 0.60 | 0.72 | 0.23 | 0.86 | 0.48 | 0.80 | 0.63 | 0.27 | 0.63 | 0.36 | 0.00 | 1.13 | 2.35 | 2.17 | 1.56 | 1.82 | 1.88 |
Lysine | ME321303 | 0.64 | 0.07 | 0.19 | 0.45 | 0.36 | 0.99 | 0.22 | 0.20 | 0.33 | 0.28 | 0.00 | 1.61 | 3.56 | 2.30 | 1.02 | 2.26 | 2.00 |
Orotic acid | ME321388 | 0.21 | 0.38 | 0.04 | 0.29 | 0.12 | 0.91 | 0.51 | 0.03 | 0.50 | 0.18 | 0.00 | 1.03 | 3.22 | 2.91 | 0.75 | 2.77 | 2.29 |
Tyrosine | ME321296 | 0.48 | 0.18 | 0.24 | 0.69 | 1.04 | 0.95 | 0.30 | 0.30 | 0.80 | 1.27 | 0.00 | 1.30 | 2.36 | 1.42 | 0.53 | 2.28 | 1.59 |
Adenine | ME321351 | 0.61 | 0.68 | 0.22 | 0.78 | 0.35 | 1.96 | 0.89 | 0.43 | 0.64 | 0.51 | 0.02 | 0.92 | 2.29 | 1.76 | 0.68 | 1.87 | 1.60 |
Hypoxanthine | ME321348 | 0.36 | 0.67 | 0.15 | 0.49 | 0.28 | 1.68 | 1.36 | 0.11 | 0.41 | 0.32 | 0.39 | 1.23 | 1.56 | 2.22 | 0.25 | 2.53 | 1.10 |
Pyruvic acid | ME321280 | 0.83 | 1.14 | 0.84 | 0.63 | 0.42 | 0.84 | 0.40 | 0.79 | 0.59 | 2.22 | 0.06 | 1.58 | 1.76 | 1.63 | 1.03 | 1.00 | 1.05 |
Adenosine | ME321349 | 0.61 | 1.11 | 1.15 | 0.53 | 0.52 | 0.53 | 0.55 | 0.56 | 0.57 | 1.79 | 0.03 | 1.71 | 0.64 | 1.86 | 0.83 | 0.75 | 2.78 |
Guanine | ME321376 | 0.45 | 0.67 | 0.25 | 0.69 | 0.26 | 1.07 | 0.68 | 0.15 | 0.79 | 1.68 | 0.03 | 0.96 | 0.91 | 2.84 | 0.25 | 1.73 | 2.52 |
Sorbose | ME321320 | 3.05 | 0.81 | 0.42 | 0.53 | 0.30 | 3.32 | 0.82 | 0.18 | 0.52 | 0.27 | 0.00 | 1.75 | 2.45 | 0.79 | 0.39 | 0.48 | 0.35 |
Glutathione | ME321356 | 2.19 | 1.19 | 0.83 | 0.36 | 0.08 | 1.41 | 1.03 | 0.93 | 0.19 | 0.09 | 0.15 | 0.37 | 2.26 | 2.44 | 0.35 | 0.45 | 0.66 |
Homoserine | ME321378 | 2.78 | 0.97 | 0.81 | 0.24 | 0.16 | 2.10 | 0.56 | 0.98 | 0.37 | 0.25 | 0.10 | 1.25 | 2.55 | 1.60 | 0.51 | 0.53 | 0.70 |
Ribonic acid-gamma-lactone | ME321390 | 2.67 | 0.99 | 1.11 | 0.12 | 0.19 | 2.36 | 0.69 | 1.00 | 0.21 | 0.17 | 0.01 | 1.27 | 2.35 | 1.66 | 0.72 | 0.38 | 0.36 |
Cellobiose | ME321319 | 0.84 | 0.37 | 0.59 | 0.59 | 0.49 | 1.92 | 0.35 | 1.03 | 0.37 | 0.37 | 0.04 | 1.49 | 3.76 | 0.66 | 0.98 | 0.44 | 1.25 |
3-Phosphoglyceric acid | ME321278 | 1.65 | 0.51 | 0.50 | 0.51 | 0.37 | 1.85 | 0.38 | 0.49 | 0.45 | 0.28 | 0.54 | 1.16 | 3.58 | 1.61 | 1.10 | 0.79 | 1.10 |
Sorbitol | ME321312 | 1.62 | 0.79 | 0.56 | 0.73 | 0.46 | 1.46 | 0.74 | 0.52 | 0.63 | 0.48 | 0.00 | 1.37 | 2.82 | 1.10 | 0.88 | 1.08 | 1.25 |
Sophorose | ME321391 | 1.58 | 0.24 | 0.88 | NA | 0.08 | 1.87 | 0.07 | 1.73 | 0.02 | 0.03 | 0.01 | 1.59 | 2.08 | 0.61 | 0.51 | 0.16 | 0.14 |
Arachidic acid | ME321332 | 1.14 | 0.29 | 0.76 | 1.26 | 0.36 | 1.70 | 0.44 | 0.62 | 0.73 | 0.48 | 0.01 | 1.50 | 2.79 | 0.89 | 0.67 | 1.90 | 0.73 |
AMP | ME321353 | 1.53 | 0.83 | 0.52 | 0.98 | 0.28 | 2.66 | 0.87 | 0.54 | 0.80 | 0.44 | 0.02 | 1.24 | 1.59 | 1.43 | 0.28 | 1.32 | 1.01 |
Galactonic acid | ME321318 | 0.90 | 0.33 | 1.22 | 0.92 | 0.66 | 2.30 | 0.57 | 0.66 | 0.83 | 0.81 | 0.06 | 0.92 | 2.32 | 0.93 | 0.65 | 1.47 | 0.88 |
IMP | ME321354 | 0.49 | 0.51 | 0.66 | 1.25 | 0.39 | 2.47 | 0.43 | 0.75 | 0.65 | 0.38 | 0.26 | 0.90 | 1.75 | 1.15 | 0.88 | 1.16 | 1.12 |
Xanthurenic acid | ME321363 | 1.53 | 0.58 | 1.36 | 0.79 | 0.41 | 2.77 | 0.92 | 1.57 | 1.22 | 0.95 | 0.08 | 1.02 | 0.82 | 0.56 | 0.52 | 0.66 | 0.40 |
2-Monopalmitoylglycerol | ME321338 | 2.04 | 0.26 | 1.04 | 0.39 | 0.19 | 2.65 | 0.44 | 0.63 | 0.71 | 0.42 | 0.38 | 2.04 | 1.12 | 0.67 | 0.77 | 0.47 | 0.40 |
Cystathionine | ME321371 | 1.98 | 0.43 | 0.63 | 0.36 | 0.49 | 2.37 | 0.43 | 0.73 | 0.85 | 0.42 | 0.04 | 1.34 | 1.67 | 0.41 | 0.91 | 1.15 | 1.92 |
Ribitol | ME321313 | 1.97 | 0.40 | 1.77 | 0.35 | 0.65 | 2.25 | 0.21 | 1.57 | 0.41 | 0.65 | 0.09 | 1.17 | 1.72 | 0.54 | 1.38 | 0.52 | 1.04 |
Sedoheptulose 7-phosphate | ME321316 | 2.08 | 0.47 | 1.67 | 0.41 | 0.46 | 2.74 | 0.35 | 1.17 | 0.38 | 0.38 | 0.02 | 1.20 | 1.82 | 0.66 | 1.46 | 0.45 | 0.97 |
Serine | ME321297 | 1.85 | 0.51 | 1.04 | 0.35 | 0.64 | 2.12 | 0.47 | 0.98 | 0.52 | 0.61 | 0.07 | 0.89 | 1.96 | 1.00 | 1.49 | 1.06 | 1.01 |
Threonine | ME321307 | 1.82 | 0.80 | 1.12 | 0.58 | 0.71 | 2.01 | 0.55 | 1.11 | 0.35 | 0.62 | 0.12 | 1.13 | 1.62 | 1.52 | 1.01 | 0.95 | 0.61 |
Ribose | ME321288 | 2.40 | 0.61 | 1.15 | 0.75 | 0.64 | 2.03 | 0.46 | 0.78 | 0.59 | 0.48 | 0.06 | 1.55 | 1.97 | 1.08 | 0.85 | 0.70 | 0.68 |
sn-Glycero-3-phosphate | ME321343 | 1.95 | 0.52 | 1.12 | 0.48 | 0.32 | 2.72 | 0.48 | 1.02 | 0.56 | 0.40 | 0.08 | 1.26 | 1.96 | 1.01 | 0.87 | 1.04 | 0.85 |
Citric acid | ME321282 | 2.37 | 0.20 | 0.39 | 0.22 | 0.16 | 2.23 | 0.12 | 0.29 | 0.31 | 0.14 | 0.00 | 1.28 | 2.08 | 0.67 | 2.81 | 1.47 | 2.03 |
Fructose 6-phosphate | ME321276 | 2.48 | 0.24 | 1.71 | 0.15 | 0.16 | 3.45 | 0.16 | 1.16 | 0.13 | 0.11 | 0.00 | 1.01 | 2.18 | 0.48 | 1.95 | 0.16 | 0.82 |
Glucose 6-phosphate | ME321275 | 2.27 | 0.37 | 1.72 | 0.21 | 0.20 | 2.77 | 0.20 | 1.18 | 0.18 | 0.16 | 0.00 | 0.97 | 2.51 | 0.52 | 2.37 | 0.23 | 0.86 |
Fructose | ME321310 | 0.11 | 1.83 | 2.28 | 0.73 | 0.29 | 0.14 | 1.11 | 1.78 | 0.77 | 0.25 | 0.00 | 0.99 | 0.13 | 1.10 | 2.57 | 0.87 | 1.79 |
sn-Glycero-2-phosphate | ME321344 | 0.67 | 0.90 | 1.22 | 1.98 | 1.74 | 0.50 | 0.72 | 1.35 | 1.66 | 1.28 | 0.81 | 0.52 | 0.69 | 0.76 | 2.79 | NA | 0.55 |
Myo-inositol | ME321314 | 0.38 | 1.56 | 0.60 | 1.18 | 0.58 | 0.50 | 1.28 | 0.55 | 1.11 | 0.65 | 0.00 | 1.59 | 0.55 | 2.52 | 0.63 | 2.10 | 0.78 |
Sucrose | ME321392 | 0.04 | 2.12 | 1.12 | 1.17 | 0.49 | 0.13 | 1.68 | 1.04 | 1.30 | 0.44 | 0.00 | 2.05 | 0.03 | 1.57 | 0.84 | 1.76 | 1.08 |
Glycine | ME321289 | 1.23 | 1.80 | 0.86 | 1.65 | 1.26 | 1.77 | 1.67 | 0.92 | 1.33 | 1.45 | 0.01 | 1.12 | 0.31 | 0.30 | 0.21 | 0.29 | 0.26 |
Methylmalonic acid | ME321383 | 0.65 | 1.01 | 0.93 | 1.66 | 1.71 | 0.85 | 0.75 | 0.75 | 1.26 | 1.89 | 0.05 | 1.08 | 0.35 | 0.90 | 0.32 | 1.33 | 0.65 |
Uracil | ME321395 | 0.83 | 1.53 | 0.35 | 1.38 | 1.02 | 1.45 | 1.68 | 0.26 | 1.30 | 1.36 | 0.05 | 1.44 | 0.50 | 1.11 | 0.41 | 1.30 | 0.69 |
2-Steroylglycerol | ME321340 | 0.81 | 0.30 | 1.88 | 0.19 | 0.08 | 1.04 | 0.17 | 2.22 | 0.79 | 0.30 | 0.10 | 0.39 | 1.33 | 0.10 | 2.33 | 0.83 | 0.25 |
Threonic acid | ME321322 | 0.87 | 0.54 | 1.94 | 0.62 | 1.38 | 0.99 | 0.55 | 2.82 | 0.65 | 1.77 | 0.04 | 0.79 | 1.13 | 0.57 | 0.39 | 0.45 | 0.72 |
Isoleucine | ME321293 | 1.21 | 0.99 | 1.97 | 0.73 | 1.25 | 1.46 | 0.96 | 1.54 | 0.81 | 1.03 | 0.12 | 0.82 | 0.58 | 0.75 | 0.59 | 0.81 | 0.80 |
Malonic acid | ME321334 | 0.53 | 0.78 | 1.82 | 0.88 | 0.94 | 0.98 | 1.11 | 2.22 | 0.99 | 0.86 | 0.52 | 0.69 | 0.72 | 0.80 | 0.59 | 0.85 | 1.03 |
Alanine | ME321290 | 0.52 | 1.11 | 2.64 | 1.41 | 1.29 | 0.51 | 0.83 | 2.42 | 1.04 | 1.46 | 0.00 | 0.60 | 0.10 | 0.65 | 0.16 | 0.89 | 0.53 |
Valine | ME321291 | 0.72 | 1.40 | 1.84 | 1.03 | 1.66 | 0.84 | 0.77 | 1.93 | 0.76 | 1.51 | 0.00 | 0.52 | 0.31 | 1.02 | 0.42 | 0.79 | 0.48 |
Capric acid | ME321324 | 0.64 | 0.63 | 0.96 | 0.84 | 0.88 | 2.86 | 0.53 | 1.08 | 0.99 | 0.87 | 1.44 | 0.54 | 1.26 | 0.61 | 1.17 | 1.07 | 0.65 |
Eicosane | ME321372 | 0.67 | 0.25 | 2.00 | 0.92 | 0.56 | 0.62 | 0.36 | 0.94 | 1.42 | 1.01 | 0.20 | 0.45 | 1.42 | 0.50 | 1.12 | 3.06 | 0.73 |
Myristic acid | ME321325 | 0.47 | 0.67 | 0.81 | 0.77 | 0.54 | 0.85 | 0.71 | 0.68 | 1.03 | 0.68 | 0.66 | 0.41 | 1.32 | 1.33 | 1.18 | 2.70 | 1.75 |
Stearic acid | ME321331 | 0.57 | 0.17 | 1.08 | 1.28 | 0.45 | 0.79 | 0.59 | 0.80 | 1.21 | 0.46 | 0.08 | 0.79 | 1.62 | 0.82 | 0.70 | 3.39 | 1.58 |
Phosphoethanolamine | ME321345 | 0.56 | 0.47 | 0.62 | 1.61 | 0.51 | 1.21 | 0.49 | 0.65 | 1.32 | 0.80 | 0.27 | 0.81 | 1.24 | 0.98 | 1.20 | 2.45 | 0.81 |
Inositol phosphate | ME321315 | 0.91 | 0.40 | 0.93 | 1.28 | 0.43 | 1.27 | 0.50 | 0.80 | 1.01 | 0.63 | 0.01 | 1.31 | 2.10 | 1.05 | 0.89 | 2.37 | 0.75 |
Palmitic acid | ME321327 | 0.69 | 0.21 | 1.26 | 1.17 | 0.54 | 0.79 | 0.51 | 0.96 | 1.23 | 0.63 | 0.05 | 0.76 | 1.99 | 0.94 | 0.89 | 2.61 | 1.17 |
Glyoxylic acid | ME321375 | 1.04 | 1.51 | 1.42 | 0.57 | 0.50 | 1.14 | 1.12 | 1.06 | 0.68 | 0.63 | 0.75 | 0.76 | 1.90 | 1.40 | 0.99 | 0.73 | 0.55 |
2-Hydroxybutyric acid | ME321360 | 0.92 | 1.42 | 2.07 | 0.53 | 0.44 | 0.92 | 0.94 | 1.55 | 0.64 | 0.45 | 1.40 | 0.97 | 1.46 | 1.30 | 1.02 | 0.73 | 0.44 |
Ketoleucine | ME321366 | 0.75 | 1.63 | 1.76 | 0.48 | 0.45 | 0.72 | 0.97 | 1.31 | 0.74 | 0.55 | 1.56 | 0.63 | 1.65 | 1.18 | 1.15 | 0.80 | 0.72 |
cis-Aconitic acid | ME321283 | 0.53 | 1.76 | 0.43 | 0.68 | 0.77 | 0.75 | 1.56 | 0.96 | 1.72 | 1.18 | NA | 0.53 | 0.78 | 1.03 | 1.75 | 1.22 | 0.48 |
Methionine | ME321298 | 1.20 | 1.39 | 0.82 | 0.76 | 0.73 | 1.84 | 1.33 | 0.63 | 0.88 | 1.03 | 0.01 | 1.10 | 0.96 | 1.31 | 0.97 | 0.74 | 0.69 |
Proline | ME321294 | 1.13 | 1.29 | 0.98 | 0.74 | 0.46 | 1.61 | 1.25 | 0.76 | 0.66 | 0.49 | 0.20 | 1.03 | 1.47 | 1.33 | 1.26 | 0.91 | 1.10 |
Glucosan | ME321364 | 1.06 | 1.66 | 1.17 | 0.79 | 0.55 | 1.32 | 1.38 | 0.96 | 0.79 | 0.56 | 0.03 | 1.33 | 0.94 | 1.32 | 0.85 | 0.91 | 0.71 |
Mannose | ME321311 | 1.25 | 1.71 | 1.28 | 0.88 | 0.43 | 1.45 | 1.39 | 0.83 | 0.78 | 0.37 | 0.00 | 1.45 | 0.99 | 1.16 | 1.02 | 0.73 | 0.84 |
Leucine | ME321292 | 0.36 | 2.04 | 0.99 | 1.13 | 0.71 | 0.51 | 1.53 | 1.23 | 0.99 | 0.90 | 0.00 | 0.98 | 0.59 | 2.15 | 0.68 | 1.05 | 0.44 |
Phosphoric acid | ME321346 | 0.79 | 1.73 | 0.92 | 1.09 | 0.70 | 0.82 | 1.30 | 0.93 | 0.92 | 0.71 | 0.00 | 0.96 | 1.05 | 1.65 | 0.77 | 0.97 | 0.96 |
Pyrophosphate | ME321347 | 0.94 | 1.17 | 1.87 | 0.54 | 0.14 | 0.70 | 0.41 | 0.95 | 0.88 | 0.23 | 0.05 | 0.39 | 1.31 | 1.35 | 1.73 | 1.71 | 1.90 |
N-Acetylaspartic acid | ME321384 | 0.43 | 0.47 | 1.52 | 0.42 | 0.61 | 0.62 | 0.54 | 1.99 | 1.32 | 0.69 | 0.17 | 0.74 | 0.89 | 1.91 | 1.54 | 0.62 | 1.06 |
Lactic acid | ME321281 | 0.63 | 0.77 | 1.33 | 1.00 | 1.30 | 0.78 | 0.50 | 1.62 | 1.22 | 2.29 | 0.48 | 0.43 | 0.87 | 0.58 | 1.09 | 0.91 | 0.69 |
3-Hydroxyisovaleric acid | ME321370 | 0.59 | 0.91 | 0.90 | 0.81 | 0.66 | 1.33 | 0.98 | 0.99 | 0.66 | 0.86 | 2.03 | 0.64 | 1.38 | 1.05 | 1.06 | 0.88 | 1.56 |
Benzoic acid | ME321369 | 0.52 | 0.95 | 1.13 | 0.90 | 0.78 | 0.74 | 0.76 | 1.22 | 1.13 | 1.07 | 2.01 | 0.57 | 1.09 | 0.90 | 1.43 | 1.22 | 0.94 |
Glycerol | ME321342 | 0.59 | 1.12 | 0.98 | 1.40 | 0.89 | 0.69 | 0.60 | 0.87 | 1.33 | 1.41 | 0.09 | 0.24 | 1.19 | 0.68 | 1.58 | 1.33 | 1.12 |
Heptylic acid | ME321377 | 0.42 | 0.77 | 1.13 | 1.37 | 1.09 | 0.35 | 0.51 | 1.38 | 1.72 | 1.18 | 0.35 | 0.37 | 0.76 | 0.69 | 1.53 | 1.94 | 0.87 |
1-Octadecene | ME321365 | 0.51 | 0.58 | 1.31 | 0.96 | 0.86 | 0.53 | 0.65 | 0.93 | 1.34 | 1.09 | 0.40 | 0.67 | 0.98 | 0.93 | 1.67 | 1.98 | 1.20 |
Azelaic acid | ME321368 | 0.55 | 0.72 | 1.02 | 1.20 | 0.83 | 0.49 | 0.50 | 1.08 | 1.46 | 1.02 | 0.36 | 0.61 | 1.14 | 0.96 | 1.39 | 1.98 | 1.24 |
Glycolic acid | ME321361 | 0.66 | 0.84 | 1.24 | 0.88 | 1.05 | 0.88 | 0.84 | 1.15 | 1.01 | 1.35 | 0.99 | 1.06 | 0.91 | 0.86 | 0.94 | 1.15 | 1.20 |
Unknown acid | ME321335 | 0.77 | 1.45 | 1.15 | 0.81 | 0.64 | 0.86 | 0.99 | 0.84 | 0.97 | 0.83 | 0.92 | 0.60 | 1.12 | 0.89 | 1.41 | 1.34 | 1.26 |
Nitrous Oxide | ME321387 | 0.42 | 1.12 | 1.14 | 0.69 | 0.91 | 0.45 | 0.73 | 1.29 | 1.30 | 1.40 | 1.28 | 0.21 | 1.02 | 0.80 | 1.67 | 1.35 | 1.07 |
Pelargonic acid | ME321323 | 0.49 | 0.86 | 1.15 | 0.98 | 0.76 | 0.62 | 0.67 | 1.26 | 1.32 | 0.95 | 1.15 | 0.64 | 1.09 | 0.80 | 1.76 | 1.66 | 0.87 |
Ethanolamine | ME321374 | 0.53 | 1.15 | 1.02 | 1.09 | 0.90 | 0.66 | 0.92 | 1.13 | 1.21 | 1.03 | 0.62 | 0.70 | 0.94 | 0.96 | 1.69 | 1.37 | 0.85 |
Iminodiacetate | ME321308 | 0.45 | 0.89 | 0.94 | 0.89 | 0.94 | 0.59 | 0.76 | 1.10 | 1.23 | 1.33 | 0.89 | 0.52 | 1.20 | 1.04 | 1.61 | 1.50 | 0.94 |
Aspartic acid | ME321301 | 1.46 | 0.48 | 1.53 | 0.64 | 0.97 | 1.35 | 0.35 | 1.40 | 0.80 | 1.07 | 0.00 | 0.74 | 0.81 | 1.72 | 0.80 | 1.21 | 0.65 |
Phenylalanine | ME321295 | 0.65 | 0.77 | 0.89 | 0.68 | 1.02 | 0.94 | 0.73 | 1.07 | 1.03 | 1.13 | 0.00 | 0.84 | 0.96 | 1.98 | 1.11 | 1.66 | 0.97 |
Niacinamide | ME321386 | 0.94 | 0.71 | 0.52 | 1.29 | 1.12 | 1.94 | 0.88 | 0.65 | 0.93 | 1.20 | 0.03 | 1.26 | 1.22 | 1.00 | 0.73 | 1.15 | 1.04 |
Isocitric acid | ME321284 | 1.13 | 0.74 | 0.95 | 0.78 | 0.65 | 1.14 | 0.79 | 0.88 | 1.07 | 0.84 | 0.57 | 0.94 | 1.08 | 1.20 | 1.11 | 2.02 | 0.94 |
Lauric acid | ME321380 | 0.59 | 0.47 | 1.11 | 0.91 | 0.94 | 1.64 | 0.62 | 1.08 | 1.00 | 1.01 | 0.58 | 1.13 | 1.38 | 0.73 | 1.17 | 1.58 | 0.93 |
Arachidonic acid | ME321333 | 1.02 | 0.49 | 1.19 | 0.71 | 1.29 | 1.20 | 0.71 | 0.47 | 0.74 | 0.60 | 0.22 | 1.34 | 1.66 | 1.05 | 2.48 | 0.95 | 1.11 |
Linoleic acid | ME321328 | 1.25 | 0.41 | 1.05 | 0.88 | 0.68 | 0.98 | 0.48 | 1.25 | 1.13 | 0.75 | 1.64 | 1.04 | 1.67 | 0.87 | 1.64 | 1.03 | 0.80 |
Elaidic acid | ME321330 | 1.19 | 0.47 | 1.34 | 0.84 | 0.56 | 0.66 | 0.57 | 1.23 | 0.90 | 0.81 | 0.46 | 1.00 | 1.32 | 0.77 | 2.00 | 1.86 | 0.87 |
Oleic acid | ME321329 | 1.26 | 0.41 | 1.20 | 0.89 | 0.54 | 0.88 | 0.51 | 1.28 | 0.84 | 0.68 | 0.58 | 1.32 | 2.07 | 0.81 | 1.85 | 1.33 | 0.63 |
Palmitoleic acid | ME321326 | 1.29 | 0.46 | 1.15 | 0.87 | 0.60 | 1.05 | 0.56 | 1.41 | 0.82 | 0.72 | 0.24 | 1.16 | 2.13 | 0.88 | 1.62 | 1.21 | 0.63 |
Phosphoenolpyruvic acid | ME321279 | 1.28 | 0.52 | 0.99 | 0.40 | 0.31 | 1.32 | 0.37 | 1.01 | 0.54 | 0.39 | 0.23 | 0.84 | 2.17 | 1.06 | 1.73 | 0.99 | 1.56 |
Pyroglutamic acid | ME321304 | 1.16 | 0.90 | 1.35 | 0.46 | 0.44 | 1.18 | 0.75 | 1.31 | 0.49 | 0.40 | 0.01 | 1.03 | 1.60 | 1.38 | 1.74 | 1.13 | 1.31 |
Threitol | ME321321 | 1.14 | 1.01 | 2.18 | 0.44 | 0.40 | 1.24 | 0.87 | 1.23 | 0.44 | 0.58 | 0.04 | 1.22 | 1.51 | 1.30 | 1.02 | 0.53 | 1.24 |
cis-4-Hydroxyproline | ME321309 | 0.64 | 1.17 | 1.61 | 0.62 | 0.44 | 0.64 | 0.76 | 1.64 | 0.94 | 0.88 | 0.83 | 0.48 | 1.17 | 1.25 | 1.86 | 1.03 | 0.85 |
Succinic acid | ME321285 | 1.19 | 0.69 | 1.77 | 0.71 | 0.76 | 1.56 | 0.64 | 1.39 | 0.71 | 0.88 | 0.04 | 0.91 | 1.24 | 0.66 | 1.68 | 0.85 | 0.90 |
Adipic acid | ME321367 | 1.03 | 0.69 | 1.71 | 0.62 | 0.64 | 1.13 | 0.81 | 1.62 | 0.81 | 0.63 | 0.38 | 1.00 | 1.33 | 1.12 | 1.68 | 1.02 | 0.59 |
beta-Alanine | ME321306 | 0.79 | 0.88 | 1.51 | 0.76 | 0.74 | 1.08 | 0.77 | 1.32 | 0.86 | 0.73 | 0.13 | 1.03 | 1.10 | 1.15 | 1.50 | 1.26 | 1.03 |
N-acetyl-Lysine | ME321385 | 0.44 | 0.84 | 0.29 | 0.14 | 0.12 | 0.43 | 0.63 | 0.37 | 0.49 | 0.11 | 0.00 | 0.71 | 1.67 | 4.93 | 2.19 | 1.66 | 1.21 |
Glucosamine 1-phosphate | ME321317 | 0.10 | 0.06 | 0.09 | 0.10 | 0.09 | 0.08 | 0.06 | 0.10 | 0.37 | 0.09 | 0.01 | 0.69 | 2.29 | 2.62 | 1.19 | 4.13 | 4.16 |
Ornithine | ME321305 | 0.03 | 0.02 | 0.02 | 0.05 | 0.04 | 0.05 | 0.04 | 0.02 | 0.27 | 0.04 | 0.00 | 0.48 | 2.39 | 3.12 | 1.61 | 3.51 | 3.98 |
Glutamic acid | ME321302 | 0.61 | 0.22 | 0.80 | 0.56 | 0.57 | 0.52 | 0.25 | 1.29 | 0.53 | 0.61 | NA | 0.74 | 0.94 | 1.34 | 2.08 | 2.03 | 2.95 |
Urea | ME321355 | 0.15 | 0.51 | 0.39 | 0.48 | 0.35 | 0.21 | 0.35 | 0.39 | 0.73 | 0.52 | 0.46 | 0.70 | 1.40 | 2.40 | 1.60 | 2.52 | 3.53 |
Factors:
F1 | Genotype:mct1_KO | Treatment:minR+Leu | Time:0 min |
F2 | Genotype:mct1_KO | Treatment:minR+Leu | Time:15min |
F3 | Genotype:mct1_KO | Treatment:minR+Leu | Time:180 min |
F4 | Genotype:mct1_KO | Treatment:minR+Leu | Time:30 min |
F5 | Genotype:mct1_KO | Treatment:minR+Leu | Time:60 min |
F6 | Genotype:oar1_KO | Treatment:minR+Leu | Time:0 min |
F7 | Genotype:oar1_KO | Treatment:minR+Leu | Time:15min |
F8 | Genotype:oar1_KO | Treatment:minR+Leu | Time:180 min |
F9 | Genotype:oar1_KO | Treatment:minR+Leu | Time:30 min |
F10 | Genotype:oar1_KO | Treatment:minR+Leu | Time:60 min |
F11 | Genotype:pb | Treatment:- | Time:- |
F12 | Genotype:qc | Treatment:- | Time:- |
F13 | Genotype:wild-type | Treatment:minR+Leu | Time:0 min |
F14 | Genotype:wild-type | Treatment:minR+Leu | Time:15min |
F15 | Genotype:wild-type | Treatment:minR+Leu | Time:180 min |
F16 | Genotype:wild-type | Treatment:minR+Leu | Time:30 min |
F17 | Genotype:wild-type | Treatment:minR+Leu | Time:60 min |