Clustering data with hclust algorithm for Plasma metabolites of known identity profiled using hybrid nontargeted methods (part-III) (Study ST001521)
HILIC NEGATIVE ION MODE (Analysis AN002535)Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 | F21 | F22 | F23 | F24 | F25 | F26 | F27 | F28 | F29 | F30 | F31 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sebacic acid | ME367894 | 0.21 | 0.30 | 0.29 | 0.79 | 20.60 | 0.20 | 0.26 | 0.29 | 0.26 | 5.46 | 1.00 | 0.23 | 0.19 | 0.22 | 0.18 | 0.21 | 0.20 | 0.18 | 0.17 | 0.17 | 0.22 | 0.16 | 0.23 | 0.26 | 0.17 | 0.27 | 0.25 | 0.21 | 0.20 | 0.23 | 0.30 |
4-Pyridoxic acid | ME367864 | 0.24 | 1.03 | 1.11 | 0.89 | 0.93 | 11.24 | 1.26 | 1.06 | 1.06 | 1.38 | 0.88 | 0.51 | 0.74 | 0.47 | 0.61 | 0.38 | 0.84 | 0.62 | 0.66 | 0.62 | 0.56 | 0.13 | NA | NA | NA | 0.11 | 0.28 | 0.50 | 0.23 | 0.31 | 0.18 |
Caprylic acid | ME367860 | 0.09 | 0.35 | 0.36 | 0.87 | 5.15 | 14.22 | 0.34 | 0.23 | 0.73 | 2.73 | 1.06 | 0.14 | 0.22 | 0.13 | 0.08 | 0.17 | 0.07 | 0.08 | 0.09 | 0.07 | 0.16 | 0.09 | 0.07 | 0.13 | 0.05 | 0.28 | 0.11 | 0.13 | 0.08 | 0.09 | 0.27 |
3-Indolepropionic acid | ME367880 | 1.02 | NA | NA | 0.16 | NA | 0.63 | NA | NA | 0.07 | NA | 0.53 | 3.28 | 0.47 | 0.01 | 3.40 | NA | 1.25 | 0.74 | 0.24 | 1.96 | NA | 0.40 | 0.38 | 0.02 | 0.56 | NA | 0.97 | 0.39 | 0.07 | 1.25 | 2.37 |
Hippuric acid | ME367870 | 1.37 | 0.26 | 0.35 | 0.58 | 0.60 | 1.14 | 0.23 | 0.40 | 0.32 | 0.41 | 1.09 | 6.18 | 0.17 | 0.11 | 5.28 | 0.11 | 2.71 | 0.18 | 0.27 | 1.76 | 0.06 | 0.82 | 0.14 | 0.34 | 0.66 | 0.21 | 1.79 | 0.24 | 0.65 | 2.03 | 0.47 |
3-Methylxanthine | ME367856 | 0.65 | NA | NA | NA | NA | 0.91 | NA | NA | NA | NA | 0.55 | 2.05 | 3.17 | 2.38 | 1.02 | 2.05 | 0.89 | 1.26 | 1.43 | 0.61 | 0.28 | 0.52 | NA | NA | NA | NA | 0.43 | 0.11 | 0.03 | 0.06 | 0.06 |
Sorbitol | ME367851 | 1.63 | 0.46 | 0.52 | 0.68 | 0.49 | 0.83 | 0.55 | 0.50 | 0.56 | 0.55 | 1.01 | 1.42 | 1.45 | 2.80 | 1.19 | 2.32 | 1.86 | 1.14 | 1.30 | 1.69 | 0.84 | 0.82 | 0.57 | 0.61 | 0.54 | 0.53 | 1.08 | 0.79 | 0.78 | 0.73 | 0.74 |
Methylcysteine | ME367861 | 0.67 | 0.17 | 0.17 | 0.20 | 0.19 | 0.45 | 0.11 | 0.11 | 0.10 | 0.10 | 0.96 | 1.47 | 2.48 | 2.61 | 2.07 | 1.55 | 1.93 | 3.80 | 2.29 | 1.94 | 1.12 | 0.73 | 0.18 | 0.41 | 0.22 | 0.23 | 0.47 | 0.52 | 0.70 | 0.52 | 0.42 |
Gentisic acid | ME367881 | 0.57 | NA | NA | 0.02 | 0.01 | 0.46 | 0.03 | 0.01 | 0.02 | 0.01 | 0.74 | 1.21 | 2.42 | 1.99 | 1.75 | 0.01 | 1.86 | 1.95 | 1.20 | 1.63 | 0.07 | 0.51 | 0.44 | 0.61 | 1.47 | 0.29 | 0.89 | 0.76 | 0.74 | 1.43 | 0.16 |
Quinic acid | ME367876 | 2.28 | NA | NA | 0.11 | NA | 0.41 | NA | NA | NA | NA | 0.53 | 1.63 | 2.07 | 1.93 | 1.93 | 0.41 | 1.75 | 1.70 | 1.91 | 1.65 | 0.67 | 0.32 | 0.06 | 0.34 | NA | 0.32 | 0.43 | 0.65 | 0.44 | 0.53 | 0.31 |
Corticosterone | ME367845 | NA | NA | NA | 2.81 | NA | 0.60 | 0.48 | NA | 0.77 | 0.31 | 0.36 | 1.64 | 0.73 | NA | 1.26 | NA | 1.02 | 0.43 | 0.34 | 1.36 | 0.33 | NA | 0.29 | 0.51 | 2.21 | NA | 0.80 | NA | 1.79 | 2.22 | 1.09 |
ADP | ME367914 | 0.52 | 1.52 | 0.56 | 0.49 | 0.34 | 1.08 | 1.47 | 0.96 | 0.65 | 1.62 | 0.64 | 1.29 | 1.28 | 1.03 | 0.85 | 3.57 | 0.64 | 0.81 | 0.60 | 0.84 | 0.34 | 1.03 | 0.20 | 0.43 | 0.34 | 0.20 | 0.60 | 0.87 | 1.26 | 1.81 | 1.71 |
Methylmalonic acid | ME367902 | 1.28 | 1.30 | 1.10 | 1.28 | 0.52 | 1.31 | 1.73 | 1.22 | 1.01 | 1.00 | 0.52 | 1.26 | 3.08 | 2.25 | 0.97 | NA | 1.18 | 1.19 | 0.72 | 1.02 | NA | NA | NA | NA | NA | 0.74 | 0.59 | 0.74 | 0.64 | 0.97 | 0.88 |
Glycocholic acid | ME367872 | NA | NA | NA | NA | 0.82 | 0.79 | 0.67 | 0.47 | 0.74 | 1.68 | 0.58 | 1.32 | 3.08 | 1.76 | NA | 0.72 | 1.04 | 1.78 | 1.90 | 0.73 | 1.32 | 0.35 | NA | 0.19 | NA | 1.52 | 0.61 | 0.47 | 0.75 | 0.31 | 0.88 |
Glycodeoxycholic acid/Glycochenodeoxycholic acid | ME367866 | 0.36 | 0.19 | 0.24 | 0.48 | 0.95 | 1.03 | 0.62 | 0.66 | 0.57 | 1.70 | 0.97 | 1.02 | 1.70 | 1.01 | 0.47 | 0.47 | 1.03 | 1.80 | 1.74 | 0.70 | 1.33 | 0.37 | 0.15 | 0.50 | 0.24 | 1.62 | 1.57 | 0.47 | 1.41 | 0.86 | 1.28 |
Chenodeoxycholic acid/Deoxycholic acid | ME367873 | 0.75 | NA | NA | 0.96 | NA | 1.10 | NA | 0.72 | 0.72 | NA | 0.59 | 0.87 | 0.62 | 0.78 | 0.53 | NA | 1.15 | 0.83 | 1.27 | 1.07 | NA | 0.37 | 0.37 | 2.24 | 0.37 | NA | 1.39 | 1.09 | 1.51 | 1.40 | 0.94 |
Indoxyl sulfate | ME367865 | 1.64 | 0.04 | 0.39 | 1.84 | 0.02 | 1.64 | 0.18 | 1.25 | 1.64 | 0.03 | 1.01 | 1.33 | 1.34 | 0.83 | 1.24 | 0.02 | 1.38 | 0.80 | 0.68 | 1.54 | 0.06 | 0.71 | 0.62 | 0.80 | 1.01 | 0.01 | 2.68 | 1.41 | 0.94 | 1.63 | 0.14 |
Vitamin C | ME367909 | 1.16 | 0.67 | 0.65 | 0.82 | 0.84 | 0.96 | 0.87 | 0.76 | 0.90 | 0.89 | 0.99 | NA | NA | 3.15 | 2.11 | NA | 1.14 | 0.85 | 0.91 | 1.17 | 0.85 | 0.87 | 0.64 | 0.75 | 0.78 | 0.65 | 1.48 | 0.93 | 1.06 | 1.27 | 0.95 |
Propionic acid | ME367868 | 1.11 | 0.72 | 1.05 | 0.90 | 0.85 | 1.27 | 0.87 | 0.62 | 1.10 | 0.53 | 0.60 | 0.62 | 0.77 | 0.89 | 0.83 | 0.77 | 1.32 | 1.38 | 1.08 | 2.38 | 1.98 | 0.50 | 0.25 | 0.59 | 2.00 | NA | 0.83 | 0.95 | 0.92 | 0.90 | 0.81 |
Salicyluric acid | ME367891 | 1.27 | 0.26 | 1.86 | 2.21 | 0.54 | 1.49 | 0.68 | 0.96 | 0.47 | 0.42 | 0.84 | 0.42 | 2.05 | 0.61 | 0.62 | 0.37 | 0.91 | 1.61 | 0.57 | 2.21 | 1.14 | 1.37 | 0.64 | 1.31 | 1.69 | 0.34 | 1.04 | 0.67 | 0.61 | 0.77 | 0.87 |
2-Phosphoglyceric acid | ME367911 | 0.91 | 1.59 | 0.99 | 0.61 | 0.63 | 1.17 | 1.35 | 2.04 | 1.68 | 1.11 | 0.77 | NA | 2.16 | NA | NA | NA | 0.76 | 0.83 | 0.67 | 1.06 | 0.72 | 1.09 | 0.38 | 1.02 | 1.00 | 0.60 | 0.58 | 0.77 | 0.93 | 1.10 | 0.90 |
3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid | ME367906 | 1.54 | 0.96 | 0.92 | 1.27 | 1.15 | 1.89 | 1.28 | 1.17 | 1.64 | 1.48 | 0.98 | 0.03 | 0.04 | 0.04 | 0.03 | 0.05 | 0.07 | 0.07 | 0.07 | 0.06 | 0.07 | 1.43 | 1.12 | 1.05 | 1.35 | 1.20 | 2.13 | 1.38 | 1.33 | 1.97 | 1.50 |
Aminoadipic acid | ME367889 | 0.73 | 0.77 | 0.86 | 0.77 | 1.07 | 1.02 | 1.35 | 1.40 | 1.52 | 1.32 | 0.96 | 0.28 | 0.36 | 0.28 | 0.33 | NA | 0.40 | 0.62 | 0.49 | 0.59 | 0.55 | 0.47 | 0.70 | 0.61 | 0.62 | 0.68 | 1.48 | 1.15 | 1.36 | 1.32 | 1.52 |
Xanthurenic acid | ME367908 | 1.45 | 0.74 | 1.03 | 1.41 | 0.58 | 1.16 | 0.87 | 1.34 | 1.59 | 1.33 | 0.88 | NA | NA | NA | NA | NA | 0.82 | 0.74 | 0.51 | 0.68 | 0.51 | 0.74 | NA | 0.66 | 1.10 | 0.85 | 1.27 | 0.69 | 0.78 | 1.41 | 1.17 |
Phosphocreatine | ME367895 | 0.77 | 0.41 | 0.76 | 0.56 | 0.54 | 1.01 | 1.29 | 1.15 | 1.20 | 0.53 | 0.63 | 0.40 | 0.60 | 0.32 | 0.48 | 0.68 | 0.84 | 1.04 | 0.80 | 0.48 | 0.85 | 0.70 | 0.81 | 0.45 | 1.01 | NA | 0.85 | 2.73 | 1.64 | 1.51 | 1.64 |
4-Hydroxymandelic acid/Homogentisic acid | ME367882 | 0.70 | 0.78 | 0.88 | 0.67 | 1.00 | 0.56 | 1.04 | 1.27 | 0.73 | 1.05 | 0.93 | 0.55 | 0.65 | 0.60 | 0.52 | 0.53 | 0.76 | 0.90 | 0.95 | 0.85 | 1.07 | 0.20 | NA | 0.15 | NA | 0.58 | 1.79 | 1.11 | 1.14 | 1.36 | 1.99 |
Lactose/Sucrose/Trehalose | ME367852 | 0.52 | 0.69 | 1.01 | 0.84 | 0.78 | 1.09 | 0.82 | 0.97 | 0.72 | 1.86 | 0.81 | 1.76 | 0.80 | 0.87 | 0.44 | 0.70 | 1.14 | 1.11 | 1.44 | 1.24 | 1.37 | 0.40 | 0.49 | 0.71 | 0.29 | 0.68 | 0.87 | 0.98 | 0.68 | 0.71 | 1.92 |
4,5-Dihydroorotic acid | ME367875 | 0.67 | 0.69 | 0.60 | 1.02 | 0.62 | 1.23 | 1.73 | 1.30 | 1.22 | 2.10 | 0.82 | 0.67 | 0.54 | 0.55 | 0.53 | 0.62 | 0.97 | 1.32 | 1.29 | 1.24 | 1.26 | 0.84 | 1.39 | 1.34 | 1.09 | 1.94 | 0.71 | 0.83 | 0.61 | 0.99 | 0.97 |
Suberic acid | ME367893 | 0.99 | 0.92 | 1.00 | 1.58 | 2.84 | 1.58 | 0.88 | 1.02 | 0.96 | 1.49 | 0.93 | 0.77 | 0.74 | 0.72 | 0.70 | 0.78 | 0.81 | 0.82 | 0.75 | 0.85 | 0.88 | 0.86 | 0.84 | 0.98 | 0.73 | 0.82 | 0.98 | 0.94 | 0.89 | 0.92 | 1.00 |
Hypoxanthine | ME367859 | 0.76 | 0.98 | 0.55 | 0.88 | 0.38 | 0.79 | 1.66 | 1.40 | 1.17 | 1.23 | 0.93 | 0.39 | 1.19 | 0.55 | 0.70 | 0.83 | 1.02 | 0.68 | 0.88 | 1.06 | 0.73 | 0.91 | 2.18 | 0.60 | 0.87 | 0.80 | 0.80 | 1.22 | 0.99 | 1.60 | 1.18 |
Erythronic acid | ME367877 | 0.67 | 1.68 | 2.01 | 1.14 | 1.63 | 0.98 | 1.15 | 1.20 | 1.09 | 1.16 | 0.77 | 1.17 | 1.32 | 1.25 | 1.29 | 1.23 | 0.96 | 0.84 | 0.93 | 0.71 | 0.90 | 1.18 | 1.03 | 0.70 | 0.97 | 1.02 | 0.98 | 0.77 | 0.51 | 0.71 | 0.72 |
Myo-inositol | ME367853 | 1.25 | 0.70 | 0.77 | 0.94 | 0.74 | 0.86 | 0.74 | 0.89 | 1.07 | 0.99 | 0.76 | 2.28 | 1.39 | 1.01 | 1.31 | 0.90 | 1.01 | 1.09 | 1.01 | 1.06 | 1.15 | 0.57 | 0.77 | 0.81 | 0.79 | 0.79 | 0.97 | 0.95 | 1.03 | 1.03 | 1.06 |
3-Phosphoglyceric acid | ME367913 | 0.51 | 0.81 | 0.90 | 0.79 | 0.60 | 1.13 | 1.45 | 1.58 | 1.43 | 1.18 | 0.98 | 0.61 | 0.79 | 0.55 | 0.48 | 0.64 | 0.92 | 0.95 | 1.09 | 0.91 | 0.68 | 1.22 | 0.69 | 1.36 | 1.06 | 1.00 | 1.07 | 0.78 | 1.12 | 1.42 | 1.24 |
Indolelactic acid | ME367879 | 0.86 | 0.60 | 0.73 | 0.70 | 0.56 | 0.87 | 0.91 | 0.91 | 0.93 | 0.76 | 1.00 | 0.65 | 0.95 | 0.89 | 0.61 | 0.60 | 0.81 | 1.14 | 1.61 | 0.99 | 0.92 | 0.64 | 0.64 | 0.67 | 0.90 | 0.60 | 1.46 | 1.36 | 1.46 | 1.42 | 1.24 |
Phenyllactic acid | ME367862 | 0.80 | 0.60 | 0.72 | 0.89 | 0.59 | 0.71 | 1.20 | 1.30 | 1.04 | 0.75 | 1.10 | 0.91 | 1.21 | 0.98 | 0.84 | 0.70 | 0.82 | 1.16 | 1.17 | 1.05 | 0.88 | 0.86 | 0.72 | 0.96 | 0.71 | 0.74 | 1.12 | 1.24 | 1.15 | 1.26 | 1.17 |
2-Hydroxybutyric acid/3-Hydroxybutyric acid | ME367863 | 1.16 | 0.92 | 0.77 | 0.79 | 1.15 | 0.92 | 1.09 | 1.16 | 1.11 | 1.15 | 1.00 | 1.21 | 0.90 | 0.69 | 1.53 | 1.56 | 0.58 | 0.62 | 0.71 | 0.75 | 0.93 | 0.78 | 1.16 | 0.98 | 1.17 | 0.75 | 1.25 | 0.94 | 0.96 | 1.16 | 1.13 |
Adipic acid | ME367896 | 1.00 | 1.01 | 1.02 | 1.33 | 1.84 | 0.92 | 0.91 | 0.95 | 0.91 | 1.24 | 0.99 | 0.90 | 0.99 | 0.88 | 0.92 | 1.03 | 0.88 | 0.86 | 0.94 | 0.91 | 0.97 | 1.14 | 1.29 | 1.34 | 1.29 | 1.18 | 0.99 | 0.92 | 0.92 | 0.87 | 0.90 |
Glutamic acid | ME367887 | 1.01 | 1.40 | 1.33 | 0.90 | 1.06 | 1.08 | 1.53 | 1.22 | 1.06 | 1.41 | 1.04 | 0.47 | 0.71 | 0.52 | 0.56 | 0.60 | 0.96 | 0.73 | 0.80 | 0.76 | 0.65 | 0.51 | 1.03 | 0.59 | 0.75 | 0.96 | 1.29 | 1.18 | 1.04 | 1.15 | 1.15 |
Pantothenic acid | ME367871 | 0.64 | 1.05 | 0.95 | 0.77 | 0.95 | 1.48 | 1.43 | 1.33 | 1.19 | 1.39 | 0.92 | 0.63 | 0.81 | 0.87 | 0.80 | 1.04 | 0.94 | 0.99 | 0.91 | 0.97 | 0.98 | 0.62 | 0.70 | 0.62 | 0.75 | 0.71 | 1.01 | 1.04 | 0.99 | 0.99 | 1.02 |
Xanthine | ME367884 | 0.89 | 1.09 | 1.04 | 1.19 | 0.92 | 0.98 | 1.45 | 1.41 | 1.31 | 1.19 | 1.02 | 0.80 | 1.05 | 0.80 | 0.81 | 0.81 | 0.76 | 0.79 | 0.83 | 0.71 | 0.83 | 0.76 | 1.05 | 0.82 | 0.87 | 0.71 | 0.86 | 1.24 | 1.12 | 1.17 | 0.91 |
3-Methyladipic acid/Pimelic acid | ME367892 | 1.27 | 1.33 | 1.47 | 1.45 | 1.38 | 0.92 | 1.03 | 1.08 | 1.07 | 1.00 | 0.96 | 0.89 | 0.87 | 0.82 | 0.84 | 0.81 | 0.87 | 0.82 | 0.86 | 0.86 | 0.84 | 0.92 | 0.83 | 0.85 | 0.80 | 0.83 | 1.16 | 1.00 | 0.99 | 0.99 | 1.00 |
Pyruvic acid | ME367883 | 1.33 | 1.69 | 1.69 | 1.41 | 0.96 | 0.87 | 1.00 | 1.05 | 0.94 | 0.69 | 0.91 | 1.04 | 0.97 | 0.92 | 1.16 | 0.96 | 0.75 | 0.86 | 0.97 | 0.86 | 0.78 | 0.73 | 0.98 | 0.87 | 0.72 | 0.91 | 1.18 | 0.89 | 1.05 | 1.09 | 0.97 |
3-Methyl-2-oxovaleric acid/Ketoleucine | ME367857 | 0.77 | 0.83 | 0.96 | 1.02 | 0.94 | 0.72 | 1.04 | 1.11 | 1.21 | 1.17 | 0.98 | 0.78 | 0.68 | 0.62 | 0.70 | 0.75 | 0.90 | 1.03 | 1.09 | 1.04 | 1.06 | 0.94 | 0.49 | 1.12 | 1.15 | 1.10 | 1.07 | 1.02 | 1.15 | 1.25 | 1.29 |
Thymine | ME367846 | 0.93 | 0.79 | 0.84 | 0.83 | 0.77 | 0.94 | 0.95 | 0.87 | 0.91 | 0.87 | 1.03 | 1.00 | 0.94 | 0.96 | 1.02 | 0.77 | 1.10 | 1.11 | 1.30 | 1.20 | 1.03 | 0.56 | 0.87 | 0.71 | 0.78 | 0.71 | 1.18 | 1.05 | 1.17 | 1.20 | 1.08 |
Aspartic acid | ME367888 | 1.03 | 1.02 | 0.91 | 0.99 | 0.92 | 0.76 | 1.05 | 0.81 | 1.00 | 0.98 | 1.03 | 0.87 | 1.15 | 0.81 | 0.96 | 1.06 | 0.91 | 1.00 | 1.08 | 0.92 | 1.01 | 0.59 | 0.75 | 0.78 | 0.69 | 0.73 | 1.15 | 1.11 | 1.21 | 1.03 | 1.29 |
Homovanillic acid | ME367878 | 0.94 | 0.95 | 0.89 | 1.15 | 1.16 | 0.90 | 1.11 | 1.00 | 1.21 | 1.10 | 1.01 | 0.75 | 0.76 | 0.70 | 0.74 | 0.82 | 0.87 | 0.98 | 0.97 | 0.94 | 0.92 | 0.52 | 0.76 | 0.78 | 0.59 | 0.65 | 1.22 | 1.18 | 1.15 | 1.23 | 1.22 |
Glyceric acid | ME367874 | 0.88 | 0.91 | 1.07 | 0.96 | 0.97 | 1.13 | 1.06 | 1.08 | 1.24 | 1.04 | 1.21 | 1.12 | 0.98 | 0.92 | 0.99 | 0.87 | 1.11 | 1.03 | 1.09 | 1.01 | 0.89 | 1.21 | 1.05 | 0.89 | 1.03 | 1.02 | 0.99 | 0.83 | 0.81 | 0.87 | 0.82 |
sn-Glycero-3-phosphate | ME367903 | 0.91 | 0.99 | 1.24 | 1.15 | 0.92 | 1.20 | 1.20 | 1.15 | 1.26 | 0.93 | 0.94 | 0.75 | 0.86 | 0.90 | 0.73 | 0.71 | 0.98 | 1.00 | 1.14 | 0.84 | 0.86 | 0.99 | 0.99 | 0.86 | 0.98 | 0.80 | 1.12 | 1.05 | 1.04 | 1.07 | 0.90 |
Azelaic acid | ME367899 | 0.93 | 0.84 | 0.86 | 1.26 | 1.45 | 1.00 | 0.90 | 1.07 | 0.97 | 1.10 | 0.93 | 0.86 | 0.92 | 1.03 | 0.77 | 0.99 | 0.97 | 1.05 | 0.84 | 0.98 | 1.00 | 0.82 | 1.04 | 1.19 | 0.78 | 1.02 | 1.02 | 0.97 | 1.02 | 1.01 | 1.22 |
Oxalic acid | ME367905 | 1.09 | 1.01 | 1.02 | 1.04 | 1.42 | 1.01 | 1.07 | 1.02 | 1.03 | 1.32 | 1.01 | 0.87 | 0.89 | 0.85 | 0.83 | 1.03 | 0.77 | 0.75 | 0.79 | 0.82 | 1.07 | 1.04 | 1.07 | 0.98 | 1.09 | 1.11 | 0.96 | 1.01 | 0.92 | 0.95 | 1.28 |
Quinolinic acid | ME367907 | 1.03 | 0.92 | 1.04 | 1.02 | 1.21 | 0.99 | 1.06 | 1.08 | 1.00 | 1.21 | 1.01 | 0.94 | 0.84 | 1.08 | 0.67 | 0.75 | 0.70 | 0.86 | 0.89 | 0.83 | 0.99 | 0.89 | 1.18 | 1.06 | 1.05 | 1.07 | 1.01 | 1.13 | 1.09 | 1.04 | 1.18 |
Lactic acid | ME367867 | 1.01 | 1.13 | 1.13 | 1.05 | 0.94 | 0.91 | 1.08 | 1.10 | 1.25 | 0.77 | 1.01 | 0.84 | 1.04 | 0.74 | 1.05 | 0.86 | 0.92 | 0.95 | 1.00 | 1.00 | 0.82 | 0.77 | 1.03 | 1.05 | 0.64 | 0.95 | 1.11 | 0.88 | 1.27 | 1.18 | 0.99 |
Uracil | ME367847 | 0.90 | 0.99 | 1.02 | 0.92 | 0.78 | 0.95 | 1.09 | 1.04 | 1.06 | 0.99 | 1.00 | 0.94 | 0.90 | 0.99 | 1.11 | 0.93 | 0.80 | 0.84 | 1.02 | 0.89 | 0.88 | 0.72 | 1.12 | 0.98 | 1.13 | 0.77 | 0.98 | 1.15 | 1.26 | 1.29 | 1.00 |
Uridine | ME367849 | 0.94 | 1.04 | 1.07 | 0.93 | 0.79 | 0.89 | 1.02 | 0.98 | 0.99 | 0.93 | 1.00 | 1.00 | 1.01 | 1.09 | 1.19 | 1.04 | 0.81 | 0.86 | 1.11 | 0.93 | 0.91 | 0.75 | 1.09 | 0.96 | 1.15 | 0.74 | 0.97 | 1.10 | 1.20 | 1.26 | 0.95 |
Fumaric acid/Maleic acid | ME367901 | 0.88 | 0.96 | 0.93 | 1.01 | 1.20 | 0.85 | 0.94 | 0.94 | 0.93 | 0.95 | 0.99 | 1.06 | 1.08 | 1.03 | 1.07 | 1.14 | 0.99 | 1.12 | 0.94 | 1.01 | 1.00 | 0.90 | 0.89 | 1.17 | 0.90 | 1.02 | 0.99 | 0.91 | 1.00 | 1.05 | 1.14 |
Malic acid | ME367898 | 0.85 | 0.95 | 0.91 | 0.97 | 1.20 | 0.85 | 0.93 | 0.95 | 0.93 | 0.96 | 1.00 | 1.08 | 1.07 | 1.03 | 1.06 | 1.14 | 0.99 | 1.14 | 0.95 | 1.03 | 0.99 | 0.92 | 0.88 | 1.21 | 0.89 | 1.04 | 0.99 | 0.91 | 0.99 | 1.04 | 1.15 |
Succinic acid | ME367897 | 0.93 | 0.87 | 0.99 | 1.19 | 0.98 | 0.89 | 0.93 | 0.93 | 0.99 | 0.89 | 1.03 | 0.91 | 1.14 | 0.90 | 0.91 | 0.90 | 0.95 | 1.17 | 1.09 | 1.08 | 0.95 | 0.91 | 0.97 | 1.12 | 0.92 | 0.86 | 0.97 | 0.97 | 1.20 | 1.09 | 1.02 |
Uric acid | ME367890 | 1.00 | 0.79 | 0.83 | 0.80 | 0.85 | 1.04 | 0.98 | 0.96 | 0.95 | 1.01 | 1.01 | 0.93 | 0.97 | 0.97 | 0.92 | 0.95 | 1.01 | 1.05 | 1.07 | 1.03 | 1.10 | 0.86 | 0.92 | 0.88 | 0.92 | 0.87 | 1.09 | 1.05 | 1.10 | 1.11 | 1.11 |
Ribothymidine | ME367848 | 0.94 | 0.87 | 0.90 | 0.91 | 0.91 | 0.94 | 1.00 | 0.96 | 0.98 | 0.97 | 1.01 | 0.99 | 0.98 | 1.04 | 1.03 | 1.05 | 0.92 | 0.98 | 1.09 | 0.93 | 1.00 | 0.69 | 1.00 | 0.94 | 0.88 | 0.92 | 1.07 | 1.06 | 1.12 | 1.17 | 1.08 |
Glucose/Fructose/Galactose | ME367850 | 1.05 | 0.93 | 0.95 | 0.98 | 0.93 | 1.04 | 0.98 | 0.95 | 1.01 | 0.97 | 0.99 | 0.95 | 0.96 | 0.96 | 0.95 | 0.94 | 0.96 | 0.99 | 1.08 | 0.98 | 0.99 | 0.85 | 0.95 | 0.89 | 0.92 | 0.98 | 1.09 | 1.03 | 1.07 | 1.09 | 1.06 |
N-Acetylalanine | ME367869 | 0.99 | 0.98 | 0.99 | 1.03 | 0.97 | 0.94 | 0.97 | 0.92 | 0.91 | 0.97 | 1.04 | 0.94 | 0.98 | 1.01 | 0.87 | 0.93 | 0.86 | 1.00 | 1.01 | 0.94 | 0.98 | 0.94 | 1.09 | 0.97 | 0.97 | 0.93 | 1.09 | 1.10 | 1.09 | 1.12 | 1.11 |
Malonic acid | ME367885 | 0.92 | 0.95 | 0.94 | 0.94 | 1.06 | 1.04 | 1.05 | 1.14 | 1.06 | 1.09 | 1.01 | 0.97 | 1.02 | 0.99 | 1.00 | 0.96 | 0.95 | 1.00 | 0.96 | 0.93 | 1.02 | 0.98 | 0.95 | 0.87 | 0.95 | 0.93 | 0.97 | 1.03 | 1.03 | 1.00 | 0.98 |
Oxoglutaric acid | ME367904 | 0.93 | 1.06 | 1.10 | 1.03 | 1.09 | 0.91 | 1.00 | 0.97 | 1.01 | 0.98 | 0.99 | 1.05 | 1.04 | 1.05 | 1.08 | 1.01 | 0.98 | 0.98 | 0.97 | 0.96 | 0.99 | 0.92 | 1.00 | 1.09 | 0.97 | 0.88 | 1.01 | 1.01 | 0.97 | 1.01 | 1.01 |
Citric acid/Isocitric acid | ME367910 | 0.99 | 0.97 | 0.94 | 1.01 | 0.95 | 0.99 | 1.00 | 0.98 | 1.01 | 0.96 | 1.00 | 1.06 | 1.05 | 1.05 | 1.10 | 1.05 | 0.98 | 1.04 | 1.05 | 1.03 | 1.05 | 0.88 | 0.92 | 1.01 | 1.00 | 0.90 | 0.93 | 0.99 | 1.03 | 0.97 | 0.98 |
trans-Aconitic acid | ME367912 | 1.01 | 1.05 | 1.05 | 1.01 | 1.03 | 0.97 | 1.00 | 0.97 | 0.98 | 0.96 | 0.97 | 1.03 | 1.07 | 1.01 | 1.06 | 1.02 | 0.95 | 1.03 | 1.08 | 1.01 | 1.04 | 0.78 | 0.81 | 0.93 | 0.90 | 0.85 | 0.98 | 0.99 | 1.03 | 0.99 | 1.04 |
Thymine-d4 [iSTD] | ME367844 | 0.94 | 0.93 | 0.93 | 0.98 | 0.99 | 1.04 | 1.07 | 1.10 | 1.07 | 1.09 | 1.05 | 0.89 | 0.84 | 0.86 | 0.91 | 0.84 | 0.96 | 0.97 | 0.95 | 0.95 | 1.00 | 0.83 | 1.07 | 1.08 | 1.04 | 1.11 | 0.98 | 1.04 | 1.06 | 1.06 | 1.06 |
2-Hydroxyglutaric acid | ME367900 | 0.99 | 1.12 | 1.12 | 1.08 | 1.04 | 1.17 | 0.96 | 1.00 | 0.99 | 0.96 | 0.96 | 0.95 | 1.05 | 1.06 | 0.95 | 0.93 | 0.96 | 0.96 | 1.00 | 0.95 | 0.99 | 0.99 | 1.03 | 1.02 | 1.00 | 1.16 | 1.02 | 0.97 | 0.99 | 0.96 | 0.97 |
Glycocholic acid-d4 [iSTD] | ME367843 | 1.00 | 1.03 | 0.97 | 0.98 | 1.00 | 1.12 | 1.01 | 1.09 | 1.00 | 1.07 | 0.99 | 0.96 | 0.99 | 1.00 | 1.02 | 0.96 | 0.99 | 0.99 | 0.94 | 0.97 | 0.99 | 1.15 | 1.09 | 1.03 | 1.11 | 1.02 | 0.97 | 0.98 | 0.95 | 0.95 | 0.97 |
2-Hydroxy-3-methyl-pentanoic acid | ME367858 | 0.92 | 0.69 | 0.76 | 0.80 | 0.92 | 0.88 | 1.00 | 0.99 | 1.00 | 0.98 | 0.98 | 0.90 | 0.95 | 0.85 | 1.03 | 0.88 | 0.82 | 0.94 | 1.04 | 0.94 | 1.04 | 0.74 | 0.98 | 1.05 | 0.99 | 0.93 | 1.11 | 1.10 | 1.22 | 1.24 | 1.36 |
N6-Acetyllysine | ME367854 | 0.89 | 0.92 | 0.99 | 1.06 | 1.04 | 0.89 | 1.17 | 1.07 | 1.12 | 1.12 | 0.93 | 0.86 | 0.94 | 1.00 | 0.85 | 0.87 | 0.90 | 0.88 | 1.02 | 0.86 | 0.92 | 0.66 | 1.02 | 0.86 | 0.91 | 0.95 | 1.06 | 1.05 | 1.10 | 1.15 | 1.21 |
Eicosapentaenoic acid | ME367855 | 1.28 | 1.23 | 1.10 | 1.16 | 0.87 | 1.25 | 1.02 | 1.44 | 1.38 | 1.36 | 1.01 | 1.10 | 0.98 | 0.59 | 0.94 | 1.13 | 1.10 | 0.77 | 0.64 | 0.86 | 0.80 | 1.03 | 0.47 | 0.68 | 0.65 | 0.39 | 1.12 | 0.98 | 0.73 | 1.06 | 0.91 |
Glucuronic acid | ME367886 | 1.22 | 0.88 | 0.98 | 1.10 | 1.32 | 1.26 | 0.87 | 1.10 | 1.06 | 1.03 | 1.09 | 1.36 | 1.18 | 1.31 | 1.11 | 0.79 | 1.21 | 1.03 | 0.98 | 0.98 | 0.99 | 1.49 | 0.62 | 0.84 | 0.95 | 0.80 | 1.01 | 0.67 | 0.69 | 0.83 | 0.77 |
Factors:
F1 | Study_Diet:Modulen | Sex:Female | Time:Baseline |
F2 | Study_Diet:Modulen | Sex:Female | Time:Day 12 |
F3 | Study_Diet:Modulen | Sex:Female | Time:Day 15 |
F4 | Study_Diet:Modulen | Sex:Female | Time:Day 5 |
F5 | Study_Diet:Modulen | Sex:Female | Time:Day 9 |
F6 | Study_Diet:Modulen | Sex:Male | Time:Baseline |
F7 | Study_Diet:Modulen | Sex:Male | Time:Day 12 |
F8 | Study_Diet:Modulen | Sex:Male | Time:Day 15 |
F9 | Study_Diet:Modulen | Sex:Male | Time:Day 5 |
F10 | Study_Diet:Modulen | Sex:Male | Time:Day 9 |
F11 | Study_Diet:NA | Sex:NA| Time:NA |
F12 | Study_Diet:Vegan | Sex:Female | Time:Baseline |
F13 | Study_Diet:Vegan | Sex:Female | Time:Day 12 |
F14 | Study_Diet:Vegan | Sex:Female | Time:Day 15 |
F15 | Study_Diet:Vegan | Sex:Female | Time:Day 5 |
F16 | Study_Diet:Vegan | Sex:Female | Time:Day 9 |
F17 | Study_Diet:Vegan | Sex:Male | Time:Baseline |
F18 | Study_Diet:Vegan | Sex:Male | Time:Day 12 |
F19 | Study_Diet:Vegan | Sex:Male | Time:Day 15 |
F20 | Study_Diet:Vegan | Sex:Male | Time:Day 5 |
F21 | Study_Diet:Vegan | Sex:Male | Time:Day 9 |
F22 | Study_Diet:Western | Sex:Female | Time:Baseline |
F23 | Study_Diet:Western | Sex:Female | Time:Day 12 |
F24 | Study_Diet:Western | Sex:Female | Time:Day 15 |
F25 | Study_Diet:Western | Sex:Female | Time:Day 5 |
F26 | Study_Diet:Western | Sex:Female | Time:Day 9 |
F27 | Study_Diet:Western | Sex:Male | Time:Baseline |
F28 | Study_Diet:Western | Sex:Male | Time:Day 12 |
F29 | Study_Diet:Western | Sex:Male | Time:Day 15 |
F30 | Study_Diet:Western | Sex:Male | Time:Day 5 |
F31 | Study_Diet:Western | Sex:Male | Time:Day 9 |