Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Control (DMSO 0.1%; v/v) and 10 µM DRB18 treated A549 lung cancer cells in vitro for 48 hours (Study ST001610)

Reversed phase POSITIVE ION MODE (Analysis AN002644)

Metabolite	Structure	F1	F2
But-2-enoic acid	ME381813	0.51	1.49
Spermidine	ME381829	0.60	1.50
Sphingosine	ME381817	0.57	1.43
Prostaglandin E2	ME381823	0.67	1.33
4-Methylpentanal	ME381820	0.62	1.38
Vanillylmandelic acid	ME381815	0.63	1.37
Leukotriene D4	ME381814	0.64	1.36
19-Hydroxyandrost-4-ene-3,17-dione	ME381836	0.65	1.35
Galabiosylceramide (d18:1/22:0)	ME381830	0.65	1.35
5b-Cyprinol sulfate	ME381821	0.79	1.21
Lactaldehyde	ME381834	0.75	1.25
(R)-3-Hydroxyhexanoic acid	ME381818	0.75	1.25
L-Palmitoylcarnitine	ME381824	0.71	1.29
Orotidine 5^-phosphate	ME381808	0.72	1.28
GSSG	ME381794	0.84	1.16
trans-Dodec-2-enoic acid	ME381833	0.89	1.11
L-Arginine	ME381845	0.87	1.13
L-Leucine	ME381849	0.88	1.12
Glycerol	ME381835	1.03	0.97
Ureidosuccinic acid	ME381807	1.03	0.97
L-Proline	ME381850	1.00	1.00
Phosphoserine	ME381841	1.00	1.00
Niacinamide	ME381819	0.93	1.07
Pyrroline hydroxycarboxylic acid	ME381816	0.93	1.07
Inosinic acid	ME381842	0.96	1.04
L-Histidine	ME381847	0.98	1.02
GSH	ME381793	1.24	0.76
L-Isoleucine	ME381848	1.21	0.79
Pyruvic acid	ME381787	1.22	0.78
NADPH	ME381792	1.22	0.78
Malic acid	ME381790	1.22	0.78
Adenosine	ME381801	1.22	0.78
L-Aspartic acid	ME381846	1.22	0.78
L-glutamine	ME381795	1.23	0.77
Thymidine	ME381809	1.23	0.77
dGTP	ME381805	1.14	0.83
Fructose 6-phosphate	ME381838	1.19	0.81
Uridine diphosphate-N-acetylglucosamine	ME381797	1.19	0.81
UTP	ME381811	1.18	0.82
Uridine 5^-diphosphate	ME381826	1.18	0.82
L-Lysine	ME381828	1.18	0.82
Succinic acid	ME381791	1.18	0.82
L-Lactic acid	ME381788	1.16	0.84
dUTP	ME381810	1.17	0.83
Glucose-6-Phosphate	ME381785	1.17	0.83
Hypoxanthine	ME381802	1.06	0.94
N-Acetyl-D-Glucosamine 6-Phosphate	ME381799	1.07	0.92
Phenylpyruvic acid	ME381837	1.08	0.92
2-Ethylacrylic acid	ME381839	1.15	0.90
dCTP	ME381812	1.10	0.90
Deoxycytidine	ME381844	1.13	0.87
(R)-3-Hydroxydodecanoic acid	ME381832	1.12	0.88
(R)-3-Hydroxybutyric acid	ME381840	1.12	0.88
D-glucose	ME381784	1.12	0.88
Dihydroxyacetone phosphate	ME381786	1.12	0.88
Glucosamine	ME381796	1.35	0.83
N-Acetyl-D-glucosamine	ME381798	1.33	0.67
AICAR	ME381800	1.31	0.69
Deoxyguanosine	ME381806	1.31	0.69
Glycine	ME381822	1.32	0.68
Glycineamideribotide	ME381843	1.32	0.68
ADP	ME381804	1.29	0.71
dGDP	ME381803	1.27	0.73
3-Hydroxy-3-methylglutaryl-CoA	ME381827	1.43	0.57
Sucrose	ME381831	1.41	0.59
Acetyl CoA	ME381789	1.35	0.58
Phosphoribosyl formamidocarboxamide	ME381825	1.38	0.62

Factors:

F1	Treatment:Control
F2	Treatment:DRB18

Data matrix