Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for Control of Topoisomerase II Activity and Chemotherapeutic Inhibition by TCA Cycle Metabolites (Study ST001658)

Reversed phase NEGATIVE ION MODE (Analysis AN002707)

Metabolite	Structure	F1	F2	F3
AC-benzyl	ME389041	2.48	0.40	0.13
Bisphenol S	ME389042	2.38	0.31	0.31
Fenson	ME389053	2.49	0.21	0.30
shinorine	ME389072	2.71	0.14	0.15
(±)-Ibotenic acid	ME388976	2.89	0.01	0.10
Midodrine	ME389063	2.96	0.04	0.01
N-hexadecanoylsphinganine	ME389069	2.97	0.01	0.02
3,4-Dihydroxy-5-(1,2,3-trihydroxypropyl)dihydro-2(3H)-furanone	ME389037	0.21	0.16	2.63
Gluconic acid (2)	ME389056	0.09	0.29	2.63
Galactosamine	ME389054	0.00	0.18	2.82
Trabodenoson	ME389073	0.01	0.16	2.83
N-(3-Carboxy-3-hydroxypropyl)-4-[(carboxymethyl)amino]homoserine	ME389064	0.00	0.01	2.99
MFCD00037215	ME389062	0.00	0.01	2.99
1-[5-(2,3,4-Trihydroxybutyl)-2-pyrazinyl]-1,2,3,4-butanetetrol	ME389034	0.00	0.01	2.99
(2S)-3-Hydroxy-2-({[(3S,4S,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]methyl}amino)butanoic acid (non-preferred name)	ME388980	0.00	0.01	2.99
N-Methyl-<scp>D</scp>-aspartic acid	ME389070	0.01	0.01	2.99
Dinoterb	ME389048	0.01	0.01	2.99
N-(4-Amino-1-carboxybutyl)glutamic acid	ME389065	0.01	0.01	2.99
DL-Glutamine	ME389051	0.01	0.01	2.98
6-deoxyinosine 5^-phosphate	ME389040	0.01	0.01	2.98
DL-Arginine (2)	ME389050	0.01	0.01	2.98
Ethylene glycol tetraacetic acid	ME389052	0.00	0.01	2.98
N-Acetylneuraminic acid	ME389067	0.00	0.01	2.98
L-Glutamic acid	ME389060	0.01	0.00	2.99
Υ-Aminobutyric acid (GABA)	ME389074	0.01	0.00	2.99
L-Histidine	ME389061	0.00	0.00	2.99
L-Aspartic acid (2)	ME389059	0.00	0.00	3.00
L-Aspartic acid	ME389058	0.00	0.00	3.00
D-(-)-Glutamine	ME389044	0.00	0.00	3.00
DL-Arginine	ME389049	0.00	0.00	3.00
Bluensidine	ME389043	0.06	0.04	2.90
1-(beta-D-Ribofuranosyl)-1,2-dihydropyrimidine	ME389033	0.02	0.05	2.93
D-(-)-Glutamine (2)	ME389045	0.00	0.07	2.93
2,3,4,5,6,7-Hexahydroxyheptanoic acid	ME389035	0.00	1.06	1.93
D-(+)-Glucose	ME389046	0.01	1.06	1.93
Gluconic acid	ME389055	0.19	0.51	2.30
(2S)-2-({[(3S,4S,5R)-2,3,4-Trihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]methyl}amino)propanoic acid (non-preferred name)	ME388979	0.00	0.70	2.30
Orotidine	ME389071	0.00	0.64	2.36
4-Hydroxyprolylthreonine	ME389038	0.07	0.48	2.45
D-Glucono-delta-lactone	ME389047	0.01	0.55	2.44
neuraminic acid	ME389068	0.02	2.92	0.06
L-(-)-Malic acid	ME389057	0.02	2.96	0.02
3-(3,4-dihydroxyphenyl)lactamide	ME389036	0.02	2.97	0.01
N-Acetyl-DL-glutamic acid	ME389066	0.02	2.97	0.01
(1R,2R,3S,5R,7R)-2-Acetamido-7-(1,2-dihydroxyethyl)-3-hydroxy-6,8-dioxabicyclo[3.2.1]octane-5-carboxylic acid	ME388977	0.06	2.12	0.82
(1R,2R,3S,5R,7R)-2-Acetamido-7-(1,2-dihydroxyethyl)-3-hydroxy-6,8-dioxabicyclo[3.2.1]octane-5-carboxylic acid (2)	ME388978	0.10	1.66	1.24
4-Oxoproline	ME389039	0.04	1.90	1.07

Factors:

F1	Treatment:HPLC fraction 4
F2	Treatment:HPLC fraction 5
F3	Treatment:HPLC fraction 6

Data matrix