Data for (Study ST000015)
(Analysis AN000032)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1-hexadecanol | 1.8322 | 1.2309 | 1.6454 | 1.1168 | 1.7259 | 1.2436 | 1.7413 | 1.6021 | 1.1986 | 1.4148 | 0.7253 | 0.3358 | 0.6394 | 0.6115 | 0.5370 | 0.3173 | 0.5956 | 0.3927 | 0.6823 | 0.3126 |
1-monostearin | 0.7131 | 0.6403 | 0.7665 | 1.5033 | 0.7458 | 1.0288 | 0.9884 | 0.8045 | 0.7957 | 0.7961 | 1.0308 | 0.7938 | 0.6237 | 2.3425 | 0.8622 | 0.6430 | 0.9060 | 0.7609 | 0.7953 | 2.2305 |
2-hydroxyvaleric acid | 1.3762 | 1.3685 | 1.6708 | 1.3147 | 2.5695 | 1.6113 | 1.9972 | 2.0293 | 1.3152 | 2.8337 | 0.1418 | 0.1224 | 0.1099 | 0.1051 | 0.1388 | 0.1547 | 0.1663 | 0.1057 | 0.4611 | 0.1541 |
3-hydroxybutanoic acid | 1.1434 | 0.7395 | 1.0146 | 0.6661 | 2.1776 | 2.2797 | 1.6261 | 1.4048 | 2.1615 | 2.6841 | 0.4762 | 0.2622 | 0.4736 | 0.6209 | 0.2102 | 0.2008 | 0.4271 | 0.1249 | 0.4236 | 0.1587 |
adenosine-5-monophosphate | 0.0545 | 0.0084 | 0.0393 | 0.5321 | 0.0054 | 0.0905 | 0.0237 | 0.0124 | 0.0965 | 0.0078 | 2.8948 | 1.6795 | 1.6177 | 2.4544 | 2.4209 | 2.2776 | 1.5496 | 1.7857 | 1.2069 | 1.3725 |
adipic acid | 2.1415 | 1.3597 | 1.1998 | 0.6852 | 1.1443 | 1.3789 | 1.3905 | 1.0896 | 0.8698 | 2.1070 | 0.6604 | 0.7254 | 0.5605 | 0.5965 | 0.6012 | 0.5035 | 0.7300 | 0.6186 | 0.7696 | 0.7039 |
alpha ketoglutaric acid | 0.2682 | 0.4205 | 0.3873 | 0.1436 | 0.3552 | 10.0651 | 0.6077 | 3.1735 | 0.1891 | 1.8194 | 0.2475 | 0.1092 | 0.1560 | 0.1818 | 0.1957 | 0.2165 | 0.2617 | 0.1899 | 0.1802 | 0.1339 |
arachidic acid | 3.1199 | 1.1181 | 1.4566 | 0.3406 | 1.7284 | 0.7914 | 1.1032 | 0.9628 | 0.6589 | 0.8483 | 0.5789 | 1.1858 | 0.6316 | 0.8929 | 0.6488 | 0.7178 | 0.7785 | 0.5539 | 0.7845 | 0.9818 |
butyl stearate | 1.5952 | 0.2195 | 1.8301 | 1.2381 | 1.8975 | 1.3255 | 1.6980 | 1.6891 | 0.3050 | 1.3477 | 0.9184 | 0.4929 | 0.7836 | 1.1534 | 0.4743 | 0.3713 | 0.1131 | 0.7464 | 1.0232 | 0.5803 |
capric acid | 1.5569 | 1.3597 | 1.5888 | 1.0007 | 1.1468 | 1.3625 | 1.9343 | 1.3381 | 1.3958 | 1.2245 | 0.6117 | 0.4644 | 0.6541 | 0.6417 | 0.5198 | 0.3701 | 0.7342 | 0.6068 | 0.7809 | 0.7298 |
cholesterol | 1.7755 | 1.1134 | 1.1867 | 2.0026 | 1.7928 | 1.7819 | 1.8217 | 1.3756 | 2.2438 | 2.0639 | 0.1704 | 0.1288 | 0.1453 | 0.1070 | 0.1704 | 0.1065 | 0.1631 | 0.1241 | 0.8327 | 0.2361 |
citric acid | 0.1443 | 0.0893 | 0.0959 | 0.0924 | 0.3399 | 0.3038 | 0.2509 | 0.2669 | 0.0637 | 0.1834 | 1.4287 | 0.3596 | 1.0825 | 0.3518 | 0.8803 | 12.0150 | 0.4118 | 1.2889 | 0.4482 | 0.5244 |
elaidic acid | 1.1326 | 2.5979 | 2.3271 | 0.3889 | 1.4582 | 0.4209 | 2.4970 | 2.3861 | 0.6298 | 0.7899 | 0.5866 | 0.6217 | 0.8662 | 0.5985 | 0.3350 | 0.6358 | 0.8842 | 0.8845 | 0.6460 | 0.3572 |
fructose | 0.8828 | 0.5871 | 1.3099 | 0.3050 | 1.3025 | 0.5827 | 1.0243 | 0.6534 | 0.3513 | 0.6164 | 1.8478 | 1.1135 | 0.7256 | 0.8313 | 2.2421 | 1.2024 | 1.5922 | 1.9778 | 0.6141 | 0.7906 |
glucose | 0.4200 | 1.7017 | 0.3929 | 0.2111 | 0.5619 | 0.3764 | 0.7056 | 0.3319 | 0.2859 | 0.3492 | 3.1660 | 2.2070 | 1.8197 | 2.2777 | 2.8715 | 0.3905 | 0.6256 | 0.7801 | 0.3709 | 0.4103 |
glycerol-alpha-phosphate | 0.7064 | 0.9597 | 1.1743 | 0.7752 | 0.6174 | 0.3706 | 1.7535 | 1.1199 | 0.8466 | 0.5151 | 1.2205 | 0.8345 | 1.1204 | 1.1557 | 1.0937 | 1.1573 | 1.6178 | 1.4127 | 0.7576 | 1.2581 |
glycine | 0.2394 | 0.2425 | 0.3028 | 0.1654 | 1.3520 | 0.2485 | 0.2756 | 0.2284 | 0.1460 | 0.2023 | 2.2926 | 1.8116 | 1.5801 | 1.4780 | 1.8971 | 1.3638 | 1.8713 | 1.7194 | 1.1438 | 1.5958 |
glycolic acid | 1.1258 | 1.6113 | 1.5449 | 0.5569 | 0.8696 | 1.4027 | 1.6823 | 1.1341 | 0.4542 | 1.5220 | 1.0719 | 0.7493 | 0.4569 | 0.6112 | 0.6700 | 0.5911 | 1.3699 | 0.9457 | 0.9983 | 1.0049 |
heptadecanoic acid | 1.6167 | 1.0145 | 1.5387 | 0.9495 | 1.7163 | 1.0873 | 1.4127 | 1.1005 | 1.1770 | 1.1755 | 0.6390 | 0.9423 | 0.6802 | 0.8636 | 0.6018 | 0.5444 | 0.6983 | 0.4966 | 0.8378 | 0.7485 |
hydroxylamine | 1.4324 | 1.4706 | 1.7854 | 1.0042 | 1.3394 | 1.5671 | 1.8546 | 1.3411 | 1.1745 | 1.5097 | 0.6924 | 0.4525 | 0.4533 | 0.4846 | 0.6545 | 0.5416 | 0.6171 | 0.6628 | 0.6745 | 0.3909 |
inosine | 0.1465 | 0.0672 | 0.0869 | 0.0869 | 0.1081 | 0.1396 | 0.2487 | 0.1121 | 0.2822 | 0.1568 | 2.5911 | 1.4350 | 1.9686 | 2.8437 | 2.5483 | 1.3854 | 1.2984 | 1.4599 | 1.4021 | 1.5644 |
inositol myo- | 0.2112 | 0.1624 | 0.3981 | 0.0676 | 0.4553 | 0.3093 | 0.3212 | 0.3120 | 0.1089 | 0.2551 | 3.7308 | 2.5271 | 2.5291 | 2.7279 | 2.5990 | 0.3589 | 0.8523 | 0.5546 | 0.6143 | 0.7629 |
isoleucine | 0.2111 | 0.1646 | 0.1569 | 0.1074 | 0.5405 | 0.2152 | 0.0787 | 0.1992 | 0.0831 | 0.2050 | 3.9925 | 1.4911 | 1.4491 | 1.5826 | 2.4402 | 1.4322 | 2.1656 | 2.1943 | 0.6394 | 1.0985 |
lactic acid | 1.0244 | 1.0592 | 0.8597 | 0.5635 | 1.1101 | 1.5950 | 1.0045 | 1.0284 | 0.6900 | 1.1746 | 1.2752 | 0.7179 | 0.6089 | 0.4774 | 1.3927 | 0.5404 | 1.5483 | 1.4957 | 0.8308 | 1.2312 |
lauric acid | 1.3775 | 1.1666 | 1.7239 | 1.1812 | 0.9241 | 1.4347 | 2.2149 | 1.3128 | 1.3905 | 0.9985 | 0.5515 | 0.4024 | 0.5847 | 0.7200 | 0.4649 | 0.5069 | 0.6835 | 0.5103 | 0.8650 | 1.0256 |
linoleic acid | 1.2911 | 1.2234 | 1.3253 | 1.2531 | 1.7363 | 1.2069 | 1.9496 | 1.1533 | 1.9715 | 2.1937 | 0.4363 | 0.2920 | 0.4529 | 0.3239 | 0.2929 | 0.3566 | 0.4947 | 0.3207 | 0.7411 | 0.6266 |
lysine | 0.0481 | 0.0550 | 0.0882 | 0.0283 | 0.2125 | 0.0403 | 0.0494 | 0.0622 | 0.0281 | 0.0443 | 4.5142 | 2.8444 | 3.4168 | 2.5894 | 2.7630 | 0.6641 | 0.6250 | 0.6789 | 0.7538 | 0.2810 |
malate | 3.4718 | 0.5632 | 2.6899 | 0.8527 | 3.8451 | 0.4772 | 0.1095 | 0.4634 | 0.8067 | 0.4694 | 1.1692 | 0.2515 | 0.8443 | 0.0500 | 0.3925 | 1.4421 | 0.1369 | 1.1144 | 0.4094 | 0.2083 |
myristic acid | 1.5188 | 1.0959 | 1.6239 | 1.1125 | 1.4670 | 1.6955 | 1.6745 | 1.1850 | 1.7454 | 1.1943 | 0.5433 | 0.4774 | 0.5883 | 0.5998 | 0.5380 | 0.4200 | 0.6093 | 0.3911 | 0.8049 | 0.4765 |
octadecanol | 1.1338 | 1.2247 | 1.3677 | 0.8169 | 3.2415 | 1.0986 | 1.2755 | 1.4321 | 0.8608 | 1.2135 | 0.9286 | 0.4529 | 0.6297 | 0.7723 | 0.6977 | 0.4369 | 0.7316 | 0.6022 | 0.5366 | 0.4336 |
oleic acid | 1.4912 | 1.1859 | 1.2338 | 1.3462 | 2.3606 | 1.3561 | 1.6346 | 0.9561 | 1.7242 | 2.0369 | 0.3274 | 0.3788 | 0.3811 | 0.3925 | 0.3413 | 0.3425 | 0.4204 | 0.2363 | 0.6726 | 0.6566 |
palmitic acid | 4.2808 | 0.7348 | 2.0781 | 2.1577 | 0.8578 | 0.7695 | 0.8674 | 0.6437 | 1.8035 | 0.6784 | 0.3505 | 0.5066 | 0.3825 | 0.4750 | 0.3276 | 0.2776 | 0.3794 | 0.2189 | 1.1328 | 0.4336 |
palmitoleic acid | 0.8752 | 0.7699 | 1.5624 | 1.2577 | 3.7509 | 0.9599 | 1.6796 | 1.0235 | 1.5378 | 1.3056 | 0.5141 | 0.3432 | 0.5525 | 0.4043 | 0.5051 | 0.4850 | 0.7039 | 0.3924 | 0.5776 | 0.3874 |
pelargonic acid | 1.6246 | 1.5381 | 1.5664 | 1.0052 | 1.1237 | 1.2200 | 1.5174 | 1.3314 | 1.2701 | 1.3549 | 0.7158 | 0.5532 | 0.6539 | 0.8240 | 0.6903 | 0.4936 | 0.6370 | 0.7928 | 0.6619 | 0.5074 |
pentadecanoic acid | 1.2752 | 0.9703 | 1.7737 | 1.1105 | 1.6845 | 1.1025 | 1.8836 | 1.1642 | 1.3377 | 1.3306 | 0.5899 | 0.4400 | 0.6504 | 0.7753 | 0.5346 | 0.3366 | 0.6400 | 0.4393 | 1.1314 | 0.6545 |
phenylalanine | 0.0285 | 0.0441 | 0.0480 | 0.0141 | 0.0922 | 0.0432 | 0.0747 | 0.0552 | 0.0335 | 0.0382 | 3.7177 | 2.0694 | 2.3821 | 2.3589 | 1.7617 | 1.8114 | 1.7129 | 1.8715 | 0.8194 | 1.2247 |
phosphoethanolamine | 0.3840 | 0.3290 | 0.3838 | 0.8237 | 0.4027 | 0.3807 | 0.5261 | 0.3316 | 0.8127 | 0.4592 | 2.2389 | 1.4661 | 1.8719 | 1.5943 | 1.9310 | 1.1173 | 1.5094 | 1.0826 | 0.9878 | 1.2689 |
phosphoric acid | 0.4790 | 0.8373 | 0.4773 | 1.1044 | 0.5954 | 0.5406 | 0.4706 | 0.8077 | 0.9139 | 0.5470 | 1.1436 | 1.2551 | 1.4634 | 1.4498 | 1.2753 | 1.5237 | 1.2362 | 1.2911 | 1.2239 | 1.3807 |
phthalic acid | 1.7294 | 1.6889 | 1.7554 | 0.8236 | 1.7079 | 1.3217 | 1.8660 | 1.4903 | 1.0539 | 1.8481 | 0.5131 | 0.3728 | 0.3945 | 0.4195 | 0.4739 | 0.3425 | 0.4932 | 0.4667 | 0.7828 | 0.5093 |
putrescine 3TMS | 1.6746 | 1.5090 | 1.5826 | 0.8330 | 1.2544 | 1.1593 | 1.8484 | 0.8894 | 1.0278 | 1.6924 | 0.7776 | 0.5139 | 0.5564 | 0.5659 | 0.7245 | 0.6657 | 0.8125 | 0.6235 | 0.7931 | 0.5041 |
ribose | 0.5135 | 0.5100 | 0.6305 | 0.3203 | 0.4264 | 0.4934 | 0.4774 | 0.5796 | 0.6263 | 0.5928 | 1.3989 | 1.0408 | 1.2602 | 1.1560 | 1.1735 | 1.3431 | 3.0476 | 1.6746 | 1.2535 | 1.7737 |
ribose-5-phosphate | 0.1228 | 0.1583 | 0.1443 | 0.0621 | 0.0638 | 0.1002 | 0.1082 | 0.0870 | 0.1274 | 0.1196 | 2.0287 | 0.7029 | 1.7738 | 1.6516 | 2.0424 | 2.1946 | 1.9165 | 1.1621 | 2.6674 | 2.7436 |
ribulose-5-phosphate | 0.1377 | 0.1594 | 0.0927 | 0.0683 | 0.0857 | 0.0758 | 0.1485 | 0.0998 | 0.1417 | 0.1257 | 1.9056 | 1.5265 | 1.4346 | 1.5536 | 2.0738 | 1.7650 | 2.5993 | 1.9488 | 1.9115 | 2.4402 |
serine | 0.6781 | 0.5412 | 0.5157 | 0.3103 | 2.4617 | 0.3175 | 0.3028 | 0.2272 | 0.1595 | 0.6366 | 2.2604 | 1.5928 | 1.2487 | 1.1115 | 1.5994 | 1.0084 | 1.1264 | 1.6662 | 0.9585 | 1.2884 |
stearic acid | 1.4376 | 1.0353 | 1.7997 | 0.6012 | 1.4805 | 0.8901 | 1.2577 | 1.0607 | 0.8337 | 0.7551 | 0.6909 | 1.7687 | 0.8678 | 0.9714 | 0.6435 | 0.7134 | 0.8142 | 0.5367 | 1.1077 | 0.8152 |
succinic acid | 1.3164 | 1.1042 | 1.1955 | 0.8829 | 0.8433 | 1.9209 | 1.1792 | 1.1899 | 0.9485 | 2.6857 | 0.6887 | 0.6415 | 0.6172 | 0.4412 | 0.4842 | 0.9083 | 0.5803 | 0.8091 | 0.6446 | 0.7514 |
sucrose | 0.5490 | 0.1607 | 0.5270 | 0.3476 | 0.5831 | 1.0345 | 0.5668 | 0.5534 | 0.2967 | 0.4534 | 2.0634 | 1.1104 | 0.4558 | 1.4686 | 2.4129 | 0.4858 | 2.8541 | 2.8979 | 0.7368 | 0.9774 |
taurine | 0.0085 | 0.0055 | 0.0135 | 0.0062 | 0.0080 | 0.0142 | 0.0131 | 0.0081 | 0.0098 | 0.0085 | 4.6440 | 4.1184 | 3.6299 | 3.6190 | 2.8670 | 0.0158 | 0.0097 | 0.0042 | 0.5236 | 0.0067 |
trehalose | 0.3767 | 0.5457 | 0.8416 | 0.2750 | 0.8781 | 0.3212 | 0.5037 | 0.4467 | 0.3161 | 0.4616 | 1.9946 | 1.2471 | 1.3179 | 1.5272 | 1.8867 | 1.4640 | 1.4079 | 1.7568 | 1.2034 | 1.5468 |
tryptophan | 0.1962 | 0.0825 | 0.1865 | 0.1117 | 0.4895 | 0.2479 | 0.2276 | 0.2314 | 0.1173 | 0.1301 | 4.2740 | 1.9391 | 2.2533 | 1.5143 | 2.1081 | 1.3155 | 1.4560 | 1.7093 | 0.5912 | 1.0782 |
tyrosine | 0.0154 | 0.0173 | 0.0267 | 0.0071 | 0.1135 | 0.0175 | 0.0287 | 0.0235 | 0.0089 | 0.0158 | 3.9956 | 2.1613 | 2.7815 | 1.9004 | 1.4314 | 1.8685 | 2.0506 | 1.9420 | 1.2265 | 0.5219 |
Factors:
F1 | Compartment:buffer | Minutes:0 | Skeletal Muscle Treatment:19 uM palmitate |
F2 | Compartment:buffer | Minutes:0 | Skeletal Muscle Treatment:2 uM palmitate |
F3 | Compartment:buffer | Minutes:0 | Skeletal Muscle Treatment:9 uM palmitate |
F4 | Compartment:buffer | Minutes:0 | Skeletal Muscle Treatment:9 uM palmitate+inhibitors (rotenone+malonate) |
F5 | Compartment:buffer | Minutes:0 | Skeletal Muscle Treatment:ethanol only |
F6 | Compartment:buffer | Minutes:20 | Skeletal Muscle Treatment:19 uM palmitate |
F7 | Compartment:buffer | Minutes:20 | Skeletal Muscle Treatment:2 uM palmitate |
F8 | Compartment:buffer | Minutes:20 | Skeletal Muscle Treatment:9 uM palmitate |
F9 | Compartment:buffer | Minutes:20 | Skeletal Muscle Treatment:9 uM palmitate+inhibitors (rotenone+malonate) |
F10 | Compartment:buffer | Minutes:20 | Skeletal Muscle Treatment:ethanol only |
F11 | Compartment:matrix | Minutes:0 | Skeletal Muscle Treatment:19 uM palmitate |
F12 | Compartment:matrix | Minutes:0 | Skeletal Muscle Treatment:2 uM palmitate |
F13 | Compartment:matrix | Minutes:0 | Skeletal Muscle Treatment:9 uM palmitate |
F14 | Compartment:matrix | Minutes:0 | Skeletal Muscle Treatment:9 uM palmitate+inhibitors (rotenone+malonate) |
F15 | Compartment:matrix | Minutes:0 | Skeletal Muscle Treatment:ethanol only |
F16 | Compartment:matrix | Minutes:20 | Skeletal Muscle Treatment:19 uM palmitate |
F17 | Compartment:matrix | Minutes:20 | Skeletal Muscle Treatment:2 uM palmitate |
F18 | Compartment:matrix | Minutes:20 | Skeletal Muscle Treatment:9 uM palmitate |
F19 | Compartment:matrix | Minutes:20 | Skeletal Muscle Treatment:9 uM palmitate+inhibitors (rotenone+malonate) |
F20 | Compartment:matrix | Minutes:20 | Skeletal Muscle Treatment:ethanol only |