Data for (Study ST000041)
(Analysis AN000062)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11-BETA-HYDROXYANDROST-4-ENE-3,17-DIONE | NA | NA | 1.2830 | NA | 1.3952 | 0.8113 | NA | NA | NA | NA | NA | 0.6747 | 0.7764 | NA |
| 17ALPHA-HYDROXYPROGESTERONE | 0.7003 | NA | NA | NA | NA | NA | NA | NA | NA | 1.1805 | 1.0035 | NA | 1.1157 | NA |
| 17BETA-HYDROXYANDROSTAN-3-ONE | 1.0068 | NA | NA | 0.8501 | 0.8411 | NA | NA | 1.1373 | 1.0588 | 1.2944 | 1.1700 | 0.8983 | 0.8317 | NA |
| 1-HYDROXY-2-NAPHTHOATE | NA | 0.6428 | 1.5324 | 1.4076 | NA | NA | 0.9295 | NA | 0.8112 | 1.4941 | NA | 0.8705 | 0.4413 | NA |
| 2,3-DIPHOSPHO-D-GLYCERIC ACID | NA | NA | NA | NA | NA | NA | NA | NA | 0.7546 | NA | 1.0947 | 1.0560 | NA | NA |
| 2`,4`-DIHYDROXYACETOPHENONE | NA | NA | NA | 0.5855 | NA | NA | 1.4145 | NA | NA | NA | NA | NA | NA | NA |
| (2-AMINOETHYL)PHOSPHONATE | NA | NA | NA | 0.8574 | NA | NA | NA | NA | NA | 0.7453 | 1.1676 | NA | NA | 1.2296 |
| 2`-DEOXYADENOSINE | 0.8257 | NA | NA | NA | NA | NA | NA | NA | NA | 1.1743 | NA | NA | NA | NA |
| 2`-DEOXYURIDINE 5`-TRIPHOSPHATE | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| 2-HYDROXYBUTYRIC ACID | 0.8947 | 0.7087 | 1.3934 | 1.0138 | 0.6939 | 0.5055 | 0.9392 | 1.3193 | 1.1165 | 1.2847 | 1.4542 | 0.8948 | 0.6233 | 0.6361 |
| 2-HYDROXYPHENYLACETIC ACID | NA | NA | NA | 0.8070 | NA | NA | 0.9576 | 0.8056 | NA | 1.5210 | 1.0474 | 1.1230 | 0.6156 | NA |
| 2-HYDROXYQUINOLINE | 1.2015 | 1.0841 | 1.2336 | 1.3087 | 0.6205 | 0.9916 | 1.0877 | 1.1688 | 0.9686 | 0.8641 | 0.9067 | 0.6969 | 0.9982 | 0.7865 |
| 2-METHYLMALEATE | 0.6169 | 1.9331 | 0.8804 | 3.4078 | 0.4653 | 1.8859 | NA | 0.7960 | 0.4921 | 0.9445 | 0.9043 | 0.7667 | 0.4688 | NA |
| 3-(2-HYDROXYPHENYL)PROPANOATE | 0.7161 | 0.6293 | 0.8599 | 0.7770 | 0.7145 | NA | 0.6695 | 1.5640 | 0.9956 | 1.2972 | 1.2156 | 1.2367 | 1.1440 | 0.5943 |
| 3,4-DIHYDROXYBENZOATE | NA | 0.8749 | NA | NA | 1.1426 | 1.0939 | NA | NA | 0.8306 | NA | 1.1967 | 0.7673 | NA | NA |
| 3-(4-HYDROXYPHENYL)LACTATE | 0.8491 | 0.6103 | 0.9431 | 0.8104 | 0.5798 | 0.8805 | 0.9792 | 1.5617 | 1.0233 | 1.1749 | 1.1255 | 1.3192 | 1.0201 | 0.6908 |
| 3ALPHA-HYDROXY-5BETA-CHOLANATE | NA | NA | NA | 0.3839 | 0.2926 | NA | NA | NA | NA | 1.6418 | 1.0200 | NA | NA | NA |
| 3BETA-HYDROXYANDROST-5-EN-17-ONE 3-SULFATE | 1.2345 | 1.5025 | 1.5077 | 1.3519 | 0.8989 | 1.2124 | 1.2788 | 0.7983 | 0.4646 | 0.8018 | 0.7983 | 1.0593 | 0.7896 | 0.6892 |
| 3-HYDROXY-3-METHYLGLUTARATE | 1.1777 | 0.8674 | 0.8060 | 0.8924 | 0.9535 | 0.8599 | 0.9709 | 1.2584 | 0.9902 | 0.9600 | 1.1277 | 1.1401 | 0.9211 | 1.0105 |
| 3-HYDROXYBENZALDEHYDE | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| 3-HYDROXYBENZYL ALCOHOL | 1.0197 | 0.6895 | 1.0062 | 0.7069 | NA | 1.3840 | 0.7430 | 1.3655 | 0.5104 | 1.0728 | 1.4818 | 0.8925 | 1.0639 | NA |
| 3-METHOXY-L-TYROSINE | 1.0470 | 1.2815 | 0.7387 | 1.0425 | 1.1451 | 1.0339 | 0.9970 | 1.2090 | 0.8620 | 0.8143 | 1.0212 | 1.1486 | 0.9147 | 0.7283 |
| 3-NITRO-L-TYROSINE | 0.6832 | NA | NA | NA | 0.5402 | NA | NA | NA | NA | 0.5156 | NA | 0.6287 | 1.1487 | 2.4835 |
| 4-AMINOBENZOATE | 1.0143 | 0.9555 | 1.0014 | 1.0036 | 1.0686 | 0.8504 | 0.9717 | 1.0812 | 0.9190 | 1.1643 | 1.0581 | 0.9960 | 0.9304 | 0.9026 |
| 4-HYDROXY-2-QUINOLINECARBOXYLIC ACID | 0.8368 | 1.0638 | 0.7584 | 1.2275 | 0.7900 | 0.9144 | 0.9359 | 0.8541 | 0.9824 | 1.1686 | 0.9147 | 1.2165 | 1.1751 | 0.8664 |
| 4-HYDROXYBENZALDEHYDE | NA | 1.3674 | NA | 0.6326 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 4-HYDROXY-L-PHENYLGLYCINE | 1.3857 | 0.8869 | 1.1859 | 0.8135 | NA | NA | NA | 0.6761 | 0.9669 | 0.8991 | NA | NA | NA | NA |
| 4-HYDROXYPHENYLACETATE | NA | NA | NA | 0.8095 | NA | NA | 0.9610 | 0.8083 | NA | 1.5264 | 1.0512 | 1.0820 | 0.6797 | NA |
| 4-METHYL-2-OXO-PENTANOIC ACID | 1.0391 | 0.9607 | 1.1076 | 1.1550 | 0.5379 | 0.8984 | 0.8988 | 0.9815 | 0.8998 | 1.1361 | 1.1705 | 1.2256 | 0.9113 | 0.8118 |
| 4-PYRIDOXATE | 0.6666 | 0.8011 | 0.8896 | 0.8611 | 0.5808 | 0.5153 | 0.4622 | 0.9058 | 1.2014 | 1.3138 | 1.3077 | 1.3384 | 1.2879 | 1.2871 |
| 5,6-DIHYDROURACIL | 0.9896 | 0.9377 | 0.9929 | 0.8897 | 0.7734 | 0.9050 | 0.8710 | 1.0713 | 1.0675 | 1.0830 | 1.0312 | 1.1878 | 0.9915 | 1.0558 |
| 5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5`-MONOPHOSPHATE | NA | 1.1888 | 0.9777 | 0.8937 | 0.7662 | NA | 1.4612 | NA | 0.9794 | 0.8314 | 1.0663 | 0.9290 | 1.0379 | 0.9637 |
| 5-AMINOLEVULINIC ACID | 1.2093 | 0.9697 | 1.0396 | 1.1716 | 0.7711 | 0.3155 | 0.8281 | 0.9513 | 1.0930 | 1.0484 | 1.0112 | NA | NA | NA |
| 5-HYDROXYINDOLE-3-ACETIC ACID | 1.0054 | 1.0938 | 1.0880 | 1.0555 | 0.8168 | 1.0248 | 1.0291 | 1.0263 | 0.9979 | 1.0023 | 0.9451 | 1.0454 | 0.9340 | 0.9462 |
| 5-METHYLCYTOSINE | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA |
| 5-OXO-PROLINE | 1.1743 | 1.2042 | 1.0628 | 1.1157 | 0.8962 | 1.0862 | 1.0952 | 0.7221 | 0.9318 | 1.0316 | 0.9497 | 0.9269 | 0.8528 | 0.9303 |
| 6-PHOSPHOGLUCONIC ACID | NA | 1.0522 | 1.0652 | NA | 1.2559 | NA | 1.1623 | 0.4684 | 0.9701 | 0.8966 | 0.9409 | NA | 0.9385 | NA |
| ADENOSINE | NA | 0.4346 | NA | NA | NA | NA | NA | NA | NA | 2.0971 | 0.4683 | NA | NA | NA |
| ADIPIC ACID | 1.0499 | NA | NA | NA | NA | NA | NA | 1.2591 | NA | 1.1452 | NA | NA | 0.9181 | 0.3686 |
| ALDOSTERONE | NA | NA | NA | 0.8045 | NA | 0.5670 | 1.2245 | 2.0663 | NA | 1.1278 | NA | NA | 0.8828 | 0.7601 |
| ALPHA-KETO-GLUTARATE | 1.0085 | NA | 0.6053 | 1.3842 | NA | NA | NA | 0.9402 | 0.6236 | 0.9430 | 1.5846 | 1.1276 | 1.1777 | NA |
| AMINOHEXANOIC ACID | 0.8311 | 1.1679 | 1.1690 | 1.1530 | 0.6955 | 1.1173 | 0.8268 | 1.0435 | 0.9850 | 1.2024 | 0.9947 | 0.9645 | 0.8903 | 0.9227 |
| AMINOHYDROXYBUTANOIC ACID | 1.1152 | 1.2892 | 0.8733 | 1.0168 | 0.9856 | 1.3888 | 0.9256 | 0.9220 | 0.7984 | 0.9157 | 0.9706 | 1.1240 | 0.6055 | 1.1024 |
| AMINOPENTANOIC ACID | 0.9614 | 1.1179 | 1.0030 | 1.0610 | 0.7502 | 1.0392 | 0.9050 | 1.1159 | 0.9893 | 1.0359 | 1.0046 | 1.0644 | 0.9283 | 1.0249 |
| ARACHIDIC ACID | NA | NA | 1.2140 | 1.0249 | NA | 0.3864 | 1.4533 | NA | 0.7796 | NA | NA | 0.2146 | 1.1589 | 1.5541 |
| ARACHIDONATE | NA | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| ARGININE | 1.0804 | 1.2243 | 1.1869 | 1.0049 | 1.0892 | 1.0766 | 1.0380 | 1.1434 | 0.8762 | NA | 0.8274 | NA | 0.8082 | 0.5563 |
| ASPARAGINE | NA | 0.7563 | 0.9408 | 0.7522 | NA | NA | NA | 0.7795 | NA | 1.7712 | NA | NA | NA | NA |
| ASPARTATE | 0.9563 | NA | NA | 1.0874 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| AZELAIC ACID | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA |
| BEHENIC ACID | 0.9762 | NA | 0.6913 | NA | 0.5800 | 0.9420 | NA | NA | 1.0116 | NA | 0.8167 | 1.1650 | 1.6521 | NA |
| BENZOATE | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.2794 | 0.7267 | NA | NA | 0.8511 |
| BILIVERDIN | 1.1041 | 1.8172 | 1.4073 | 2.0272 | 0.7268 | 0.5708 | 1.0794 | 0.6942 | 0.3735 | 0.9076 | NA | 0.2402 | NA | NA |
| BIOTIN | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.3255 | 0.6745 | NA | NA | NA |
| BOC-ALA-OH | 0.9781 | 1.0271 | 1.1064 | 0.9881 | 0.6924 | 0.9570 | 0.9135 | 1.1734 | 1.0095 | 1.1504 | 1.0231 | 1.1137 | 0.8756 | 0.9610 |
| BOC-ASN | 0.2576 | 0.4481 | 0.3483 | 4.0311 | 0.5030 | 0.4205 | 0.5542 | NA | 0.4317 | NA | 2.0054 | NA | NA | NA |
| BOC-ASN-OH | 1.0481 | 1.0485 | 1.0563 | 0.9725 | 0.8638 | 1.0031 | 0.9358 | 1.0114 | 0.9814 | 1.0002 | 0.9686 | 1.1265 | 0.9493 | 1.0432 |
| BOC-ASP-OH | 1.0158 | 0.9605 | 1.1299 | NA | 1.0341 | 0.8964 | 0.9317 | NA | 1.0448 | NA | 0.9484 | 1.0597 | 0.9121 | 0.9856 |
| BOC-HIS-OH | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| BOC-PHE-OH | 0.9872 | 1.1039 | 1.1227 | 1.0847 | 0.7888 | 1.0321 | 1.0162 | 1.0385 | 0.9932 | 1.0177 | 0.9403 | 1.0502 | 0.9128 | 0.9092 |
| BOC-PRO-OH | NA | NA | NA | NA | NA | NA | NA | 1.2885 | NA | NA | NA | 0.7577 | 0.8292 | 1.3669 |
| BUTANOATE | NA | NA | NA | NA | NA | NA | NA | 1.3722 | NA | 0.6278 | NA | NA | NA | NA |
| [C13] METHIONINE | 0.9935 | 0.9588 | 0.9552 | 0.9128 | 0.7858 | 0.9494 | 1.0319 | 1.1054 | 1.0565 | 1.0704 | 1.0162 | 1.0405 | 1.0032 | 1.0543 |
| [C13] PHENYLALANINE | 0.9633 | 0.9410 | 0.9172 | 0.9204 | 0.6432 | 0.9194 | 0.9204 | 1.0154 | 1.0888 | 1.1273 | 1.1274 | 1.1265 | 1.0366 | 0.9996 |
| [C13] TYROSINE | 1.0038 | 0.9746 | 1.0243 | 0.9718 | 0.7479 | 0.9723 | 1.0812 | 1.0902 | 1.0035 | 1.0409 | 1.0680 | 1.0058 | 0.9840 | 0.9607 |
| [C13] VALINE | 0.9578 | 0.9564 | 0.9281 | 0.9416 | 0.7994 | 0.9510 | 1.0825 | 1.1709 | 1.0287 | 1.0567 | 1.0816 | 0.9911 | 0.9564 | 1.0811 |
| CAPRYLIC ACID | 1.0367 | 1.0709 | 1.2555 | 1.1956 | 0.6917 | 1.2322 | 0.9278 | 0.5991 | 1.0066 | 1.2497 | 0.8767 | 0.9818 | 1.0230 | 0.5675 |
| CATECHOL | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA |
| CHENODEOXYCHOLATE | 0.4978 | 0.8385 | 0.7039 | 0.4284 | 1.4016 | 0.8696 | 0.6081 | 0.7876 | 1.0142 | 1.7020 | 1.8101 | 0.7766 | 1.1751 | 0.4031 |
| CHOLATE | 0.7231 | 0.8465 | 1.3396 | 0.7082 | 0.5130 | 1.0611 | 0.7388 | NA | 0.9193 | 2.0979 | NA | NA | 0.6462 | NA |
| CHOLESTEROL SULFATE | NA | NA | 0.6586 | 4.0056 | NA | 0.4690 | 0.1463 | 0.5242 | NA | 1.1467 | NA | 0.5254 | NA | NA |
| CHOLINE PHOSPHATE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 |
| CIS-11-EICOSENOIC ACID | NA | 2.1605 | 1.1442 | 0.1371 | NA | NA | 0.9055 | 0.7121 | 0.1950 | 1.4681 | 1.4892 | NA | 0.1548 | NA |
| CIS-7,10,13,16-DOCOSATETRAENOIC ACID | 1.4831 | 0.6573 | NA | 0.6025 | NA | NA | 1.6144 | NA | 0.5440 | 1.1923 | 0.5889 | 1.3736 | 0.7518 | NA |
| CITRATE | 0.9896 | 0.7185 | 0.8418 | 0.9826 | 0.5117 | 0.6254 | 0.6172 | 1.1673 | 1.0325 | 1.4936 | 1.5118 | 1.1742 | 0.9483 | 0.6104 |
| CITRULLINE | NA | NA | NA | NA | 1.0478 | 0.9522 | NA | NA | NA | NA | NA | NA | NA | NA |
| CORTICOSTERONE | NA | 1.2281 | NA | 1.5683 | 0.9589 | 1.1624 | 0.7685 | 1.0607 | 0.9923 | 0.7386 | NA | 0.8645 | NA | NA |
| CREATINE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA |
| CREATININE | 0.9676 | 0.9889 | 1.0372 | 0.9756 | 0.7137 | 0.9900 | 1.0098 | 1.1436 | 0.9555 | 1.0703 | 1.0606 | 1.1093 | 0.9367 | 0.9502 |
| CYCLOHEPTANECARBOXYLIC ACID | 1.0173 | 1.1626 | 1.1707 | 1.0467 | 0.6250 | 1.0984 | 0.6684 | 1.7493 | 0.8908 | 1.4624 | 0.7800 | 1.1740 | 0.5808 | 0.2598 |
| CYS-GLY | 1.0957 | NA | NA | NA | NA | NA | NA | 0.9402 | NA | 1.0708 | NA | 0.8933 | NA | NA |
| CYSTEIC ACID | 0.5257 | 1.5359 | 1.4642 | 1.1377 | 2.0442 | 0.4806 | 0.8211 | 1.0926 | 0.9098 | 0.9067 | 0.6017 | 1.3722 | 0.6334 | 0.5412 |
| CYSTINE | 0.9832 | 0.7679 | NA | NA | 1.1035 | NA | 1.2047 | 0.9763 | 1.2955 | 1.2336 | 0.8000 | 0.9538 | 1.0420 | 0.8856 |
| CYTIDINE 5`-DIPHOSPHATE | NA | NA | NA | NA | NA | 1.1038 | NA | NA | 1.0080 | NA | NA | NA | 0.8802 | NA |
| DECANOATE | 0.5836 | 1.2602 | 1.9941 | 1.6205 | 0.7217 | 1.2281 | 0.9885 | 0.8522 | 0.8012 | 1.1861 | 1.0054 | 0.4716 | 0.8264 | 0.6354 |
| DEHYDROASCORBATE | 1.0411 | 0.8909 | 1.0354 | 1.0233 | 0.6018 | 0.6150 | 0.7337 | 1.3825 | 1.0566 | 1.4229 | 1.2128 | 1.1816 | 0.8283 | 0.4586 |
| DEOXYCORTICOSTERONE ACETATE | NA | NA | 0.7709 | NA | NA | NA | NA | NA | NA | 1.2291 | NA | NA | NA | NA |
| DEOXYRIBOSE | 0.7611 | 1.0143 | 0.6949 | 1.0061 | 0.8284 | 0.7809 | 0.7245 | 1.1321 | 1.0620 | 1.0441 | 1.0317 | 1.5325 | 1.1855 | 1.0724 |
| DETHIOBIOTIN | NA | NA | NA | NA | NA | NA | 1.3656 | NA | NA | 1.1061 | NA | NA | 0.5284 | NA |
| DIETHYLSTILBESTROL | NA | NA | NA | 1.0059 | NA | 1.2550 | 1.1900 | NA | NA | NA | NA | 0.7746 | NA | NA |
| DIHEXOSE | NA | NA | NA | 0.7191 | 0.7748 | 0.6217 | 0.8447 | 0.9883 | NA | 1.2995 | 0.9594 | 0.9789 | 1.3014 | 0.8289 |
| DIMETHYLXANTHINE | NA | NA | NA | NA | NA | 0.8781 | NA | NA | NA | 0.8317 | 1.2902 | NA | NA | NA |
| DOCOSAHEXAENOIC ACID | NA | NA | NA | NA | NA | NA | NA | NA | 1.2287 | 0.8559 | 0.9587 | 0.9980 | NA | NA |
| ESTRONE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| FERULATE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.1201 | NA | 0.8799 |
| FORMYL-L-METHIONINE | 0.6107 | 0.7111 | NA | 1.2917 | 0.5734 | 1.2598 | 0.7750 | NA | 0.8389 | 1.2340 | 1.8075 | 0.8918 | 1.1697 | NA |
| FUMARIC ACID | 1.0497 | 1.0022 | 0.6839 | 1.0846 | 1.1610 | 0.7627 | 1.1336 | 0.7874 | NA | 1.2619 | 1.1732 | 0.9725 | 0.8660 | NA |
| GLUCARIC ACID | 0.8741 | 1.0074 | NA | 1.1184 | 0.9147 | 1.0667 | 1.0173 | 1.5196 | 0.7997 | 0.8158 | 1.1593 | 1.0876 | 0.9945 | NA |
| GLUCURONOLACTONE | NA | NA | NA | 0.8364 | NA | NA | NA | 1.1101 | NA | NA | 1.1621 | 0.9457 | NA | NA |
| GLUTAMIC ACID | 0.6317 | 0.8532 | 1.0740 | 1.5039 | 1.3558 | NA | 1.0410 | 2.1549 | 0.9605 | 1.2068 | 0.8251 | 0.9018 | 0.9251 | 0.5345 |
| GLUTAMINE | 1.1187 | 1.1178 | 0.9943 | 1.0261 | 1.0427 | 1.1034 | 1.0372 | 1.0532 | 0.9588 | 0.9660 | 0.9802 | 0.9464 | 0.8133 | 1.0195 |
| GLUTARATE | 1.0367 | 0.8248 | 0.8478 | 0.8665 | 0.9817 | 0.7553 | 0.9940 | 1.4599 | 1.0043 | 1.0465 | 1.0250 | 1.1382 | 0.9613 | 0.9408 |
| GLYCERIC ACID | NA | NA | 0.7552 | NA | NA | NA | NA | NA | 1.2448 | NA | NA | NA | NA | NA |
| GLYCOCHOLATE | 0.6319 | 0.8573 | 1.0408 | 0.7119 | 0.2433 | 1.3694 | 0.3698 | 0.8567 | 1.3710 | 1.8981 | 1.6818 | 0.5832 | 0.8334 | 0.7349 |
| GUANIDINOACETATE | NA | NA | 1.1644 | NA | NA | 0.8356 | NA | NA | NA | NA | NA | NA | NA | NA |
| GUANOSINE | 0.8507 | 1.4052 | 1.9457 | 0.2855 | 3.1363 | 1.6608 | 1.3155 | NA | 0.7007 | 0.4200 | 0.4265 | 0.6210 | 0.9642 | 0.2611 |
| HEPTANOIC ACID | 1.0442 | NA | NA | 1.1580 | NA | 1.1994 | 0.8377 | NA | 1.0738 | 1.0390 | 0.8743 | 0.9200 | 0.7409 | NA |
| HEXACOSANOIC ACID | NA | NA | NA | 1.4334 | NA | NA | NA | 0.6039 | NA | 0.4592 | 1.0350 | NA | NA | NA |
| HEXANOATE | 0.9477 | NA | 1.2610 | 0.8672 | NA | 1.2842 | NA | 0.4436 | 1.5276 | 0.8754 | 1.1251 | 1.2410 | NA | NA |
| HEXURONIC ACID | 0.9096 | 1.0643 | 1.0531 | 1.2355 | 0.8037 | NA | NA | 1.5839 | NA | NA | 0.7799 | NA | 0.5700 | NA |
| HIPPURATE | 0.5985 | 0.6827 | 0.9465 | 1.0185 | 0.6444 | 0.9684 | 0.0588 | 2.2686 | 1.0936 | 0.9721 | 0.9610 | 1.7034 | 0.8921 | 0.7609 |
| HISTIDINE | 1.1150 | 1.1764 | 1.0676 | 1.0286 | 0.8562 | 1.0130 | 1.0338 | 0.9055 | 1.0022 | 0.9515 | 0.9655 | 0.9502 | 0.9623 | 1.0468 |
| HOMOCYSTEINE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.9624 | 1.0376 | NA |
| INDICAN | 0.5410 | 0.7368 | 0.6597 | 0.8322 | 0.4122 | 1.2633 | 1.6936 | 1.1449 | 1.1075 | 1.3558 | 1.4362 | 0.8030 | 0.8363 | 0.8160 |
| INDOLE-3-ACETIC ACID | 1.0542 | 1.3285 | 0.9005 | 1.1687 | 0.6496 | 0.7573 | 0.7857 | 0.9202 | 1.1741 | 0.7431 | 0.3607 | 2.0865 | 1.1711 | 0.6727 |
| INOSINE | 0.2807 | 0.8476 | 0.9237 | NA | 2.9973 | 1.2566 | 1.4848 | NA | 1.2032 | 0.6784 | 0.7107 | 0.4649 | 1.1422 | 0.4871 |
| ISOLEUCINE | 1.0428 | 1.2084 | 1.2140 | 1.1954 | 0.3577 | 0.5932 | 0.9813 | 1.1388 | 0.7212 | 1.1569 | 1.1174 | 1.1948 | 1.0024 | 0.9583 |
| KYNURENINE | 1.0556 | 1.0036 | 0.9568 | 0.8850 | 0.4416 | 0.9678 | 1.2121 | 0.9690 | 1.1092 | 1.0240 | 1.1614 | 1.0248 | 1.0648 | 0.8642 |
| LAURIC ACID | NA | NA | NA | NA | NA | 0.9508 | NA | 1.0671 | NA | NA | NA | 0.9821 | NA | NA |
| LAUROYLCARNITINE | 1.2582 | 1.5337 | 0.8902 | 0.9536 | 1.8261 | 1.0416 | 0.9967 | 0.5875 | 0.7224 | 0.5727 | 0.7962 | 1.1081 | NA | NA |
| LIGNOCERIC ACID | NA | NA | NA | 0.7375 | NA | NA | NA | NA | 0.7886 | 1.3307 | NA | 1.1064 | 0.9303 | NA |
| LINOLEATE | 1.8527 | 0.9353 | 0.8545 | 0.6658 | 0.4519 | NA | 1.1199 | NA | NA | NA | NA | NA | NA | NA |
| MALATE | 1.1708 | 0.8488 | 0.9399 | 1.1188 | 0.5950 | 0.7559 | 0.8503 | 1.0681 | 0.9239 | 1.2484 | 1.2812 | 1.1589 | 0.9199 | 0.7080 |
| MELATONIN | 1.2158 | 1.4266 | 1.1741 | NA | 0.9695 | NA | 1.5387 | 0.9673 | 1.0372 | 0.9018 | 0.5791 | 0.7836 | 0.3739 | NA |
| MENAQUINONE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| METHIONINE | 1.0751 | 1.2177 | 1.0069 | 1.1087 | 0.8346 | 1.1625 | 1.0043 | 0.8833 | 0.9634 | 1.0318 | 0.9590 | 1.0285 | 0.8720 | 0.8498 |
| METHYL BETA-D-GALACTOSIDE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.1280 | 0.8866 | 0.9330 | 1.0524 |
| METHYL INDOLE-3-ACETATE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA |
| METHYL VANILLATE | NA | NA | NA | NA | NA | 0.8121 | NA | NA | NA | NA | NA | 0.9759 | 1.2121 | NA |
| MYO-INOSITOL | 0.9821 | 0.8859 | 0.9858 | 1.0727 | 0.9435 | 0.9199 | 0.9027 | 1.2408 | 0.9619 | 1.1290 | 1.0221 | 1.0419 | 0.9042 | 0.9562 |
| MYRISTIC ACID | 1.3007 | 1.4120 | NA | 1.4786 | 1.1087 | 0.8814 | 0.8100 | NA | 1.0256 | 0.4352 | 0.8311 | 0.6700 | 0.9574 | 1.0309 |
| N-ACETYL-DL-GLUTAMIC ACID | NA | NA | 1.5225 | NA | NA | NA | NA | 0.6966 | 1.1628 | 1.3436 | 1.2241 | 0.4265 | 0.6999 | NA |
| N-ACETYL-DL-METHIONINE | NA | NA | NA | NA | NA | 0.8978 | NA | NA | NA | 1.3914 | 0.7108 | NA | NA | NA |
| N-ACETYL-L-ASPARTIC ACID | NA | NA | 1.4947 | 0.8109 | 0.6962 | NA | NA | 0.8452 | 0.9471 | 1.2059 | NA | NA | NA | NA |
| N-ACETYL-L-LEUCINE | 0.9937 | 0.9147 | 0.9061 | 0.8868 | 0.6735 | 0.9896 | 0.9728 | 0.9962 | 1.1548 | 0.7903 | 1.1701 | 1.1909 | 1.0985 | 1.1195 |
| N-ACETYL-L-PHENYLALANINE | 1.1545 | 0.9293 | 0.9859 | 1.1743 | 0.6792 | 1.2512 | 0.9457 | 1.0901 | 0.9164 | 0.7907 | 0.8928 | 1.1367 | 0.9329 | 0.9861 |
| N-ACETYLNEURAMINATE | 1.2954 | 1.3014 | 1.8940 | 0.6191 | 0.5167 | 1.6356 | 1.1594 | 0.8081 | 0.9535 | 1.0524 | 0.5150 | 0.7520 | 1.2019 | 0.9459 |
| N-ACETYLSEROTONIN | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| N-ALPHA-ACETYL-L-LYSINE | 0.6431 | 0.7814 | 0.6863 | 1.2064 | 1.4678 | NA | NA | NA | NA | 1.2123 | 1.1832 | 1.0103 | 0.6967 | NA |
| N-AMIDINO-L-ASPARTATE | NA | NA | 1.0889 | NA | NA | NA | NA | NA | 0.9172 | NA | NA | NA | 0.9970 | NA |
| N-BENZYLOXYCARBONYLGLYCINE | NA | NA | NA | NA | NA | 0.7809 | NA | NA | NA | NA | NA | 1.2191 | NA | NA |
| NERVONIC ACID | NA | NA | 0.4826 | 2.2864 | NA | NA | NA | 0.6650 | NA | 0.5660 | NA | NA | NA | NA |
| N-FORMYLGLYCINE | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA |
| NONANOATE | 1.1276 | 1.2115 | 1.1685 | 1.2522 | 0.4870 | 1.2221 | 1.0534 | 0.6201 | 0.8663 | 1.1008 | 1.1389 | 1.0374 | 0.9512 | 0.4314 |
| NORADRENALINE | NA | NA | NA | NA | NA | NA | NA | NA | 0.6463 | 1.3537 | NA | NA | NA | NA |
| N(PAI)-METHYL-L-HISTIDINE | NA | NA | NA | NA | NA | NA | NA | NA | 0.8539 | 1.1627 | NA | 0.9833 | NA | NA |
| OLEATE | 1.1732 | 0.7252 | 1.1740 | 1.1309 | 0.5221 | 1.1671 | 1.0784 | 0.7713 | 0.7018 | 1.0134 | 1.1937 | 1.2078 | 1.1545 | 1.1730 |
| OROTIDINE 5`-MONOPHOSPHATE | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| OXALATE | NA | 1.0932 | 1.1722 | 1.4848 | 1.1768 | 1.2609 | 0.7454 | 1.2062 | 0.8404 | 0.8760 | 0.7645 | 0.6584 | 0.9663 | 0.7217 |
| PALMITIC ACID | 1.0812 | 1.0325 | 1.2590 | 1.9581 | 0.7336 | 0.8676 | 1.2572 | 0.9409 | 0.8367 | NA | 0.7812 | 0.7320 | 1.0337 | 1.0654 |
| PALMITOLEIC ACID | NA | NA | NA | 1.5735 | NA | NA | 0.8015 | NA | NA | 1.1474 | 0.7246 | 0.7531 | NA | NA |
| PANTOTHENIC ACID | 1.2205 | 0.9243 | NA | NA | 0.7258 | 1.0061 | 1.0250 | NA | 1.0083 | NA | NA | 0.9397 | 1.2526 | 0.8645 |
| P-BROMO-DL-PHENYLALANINE | 1.0146 | 1.1045 | 0.9796 | 0.7634 | 1.0605 | 1.0515 | 1.3361 | 0.8954 | 0.9208 | 1.0004 | 0.8607 | 1.0513 | 1.0357 | 1.0689 |
| PENTANOATE | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA |
| PENTITOL | 1.0371 | 0.8996 | 1.0168 | 1.0301 | 0.8983 | 0.8921 | 1.0819 | 1.0583 | 0.7236 | 1.1850 | 1.1167 | 1.0991 | 0.9452 | 0.9627 |
| PHENYLACETALDEHYDE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA |
| PHENYLACETIC ACID | 0.9348 | 1.0611 | 0.8404 | 0.8640 | 0.7389 | 1.1625 | 1.3255 | 1.0341 | 0.9722 | 1.1259 | 1.0104 | 1.0570 | 0.8994 | 0.9470 |
| PHENYLALANINE | 0.9726 | 0.9486 | 0.8902 | 1.0239 | 0.6144 | 0.8916 | 0.8499 | 0.9400 | 1.0540 | 1.1596 | 1.0856 | 1.2432 | 1.0614 | 0.9265 |
| PHENYLPYRUVATE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| PHOSPHATE | NA | NA | NA | NA | 1.5345 | 0.0984 | NA | 2.2759 | NA | NA | 0.0912 | NA | NA | NA |
| PIPECOLATE | 0.8260 | 0.5721 | NA | NA | NA | 0.9266 | NA | NA | 1.5485 | 1.1674 | 0.9122 | 1.1355 | 1.2480 | 0.8157 |
| PREGNENOLONE | 1.6626 | NA | 1.2528 | NA | 0.5951 | NA | NA | NA | NA | 1.0417 | 0.6648 | NA | 0.7413 | NA |
| PROGESTERONE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA |
| PROLINE | 1.0636 | 1.0045 | 0.8300 | 0.9659 | 0.5658 | 1.1911 | 0.9082 | 1.0747 | 0.8731 | 1.0047 | 0.9616 | 1.1927 | 1.0422 | 1.1353 |
| PURINE | NA | NA | NA | NA | NA | 1.0067 | NA | 0.9933 | NA | NA | NA | NA | NA | NA |
| PYRIDINE-2,3-DICARBOXYLATE | 1.5616 | 0.8183 | 0.6722 | 0.9767 | 0.7632 | 0.9052 | NA | 0.8617 | 1.1958 | 0.7929 | 1.0009 | 1.2485 | 1.2959 | NA |
| PYRIDOXAL | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA |
| PYRUVATE | 0.9297 | 1.0008 | 1.0033 | 1.1883 | 0.7345 | 0.6817 | 0.7290 | 1.0254 | 0.8436 | 1.0120 | 0.9786 | 1.5871 | 0.9359 | 1.0723 |
| RAFFINOSE | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.7509 | 1.4117 | 0.8374 | NA | NA |
| RETINOATE | NA | 0.8632 | NA | 0.7263 | NA | 0.9416 | 1.1671 | 1.6428 | NA | 0.7524 | NA | 0.9533 | NA | NA |
| RIBOFLAVIN | NA | NA | 1.3328 | NA | NA | NA | 1.1137 | NA | 0.5535 | NA | NA | NA | NA | NA |
| RIBOSE 5-PHOSPHATE | NA | NA | 1.1430 | NA | NA | NA | NA | NA | 0.8570 | NA | NA | NA | NA | NA |
| ROSMARINIC ACID | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| SALICYLAMIDE | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA | NA |
| SALICYLIC ACID | 2.1279 | 2.3840 | 0.6073 | 1.7737 | 1.1930 | 0.4067 | 0.5532 | 1.4906 | 0.6409 | 0.7643 | 0.6731 | 1.1549 | 0.6403 | 0.4870 |
| S-CARBOXYMETHYL-L-CYSTEINE | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| (S)-DIHYDROOROTATE | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| SELENOMETHIONINE | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| SERINE | NA | 1.6410 | NA | NA | NA | NA | NA | 0.8295 | 0.5295 | NA | NA | NA | NA | NA |
| (S)-LACTATE | 1.2955 | 1.6503 | 0.8235 | 1.2654 | 0.9436 | 1.0344 | 0.9351 | 1.0516 | 0.7772 | 0.8237 | 0.8629 | 1.0778 | 0.7550 | 1.1114 |
| STEARATE | 1.2327 | 0.9524 | NA | 1.0659 | 0.8489 | 1.0966 | 0.4280 | 0.9097 | 1.2016 | 1.0176 | 2.0350 | 0.7286 | 0.6926 | 0.5807 |
| SUCCINATE | 0.9408 | 0.9525 | 0.9818 | 0.9870 | 0.7092 | 1.1214 | 1.0135 | 1.1788 | 0.8444 | 1.1403 | 1.0533 | 1.0450 | 1.0068 | 0.9606 |
| TAURINE | 1.4326 | 1.0280 | 0.9402 | 1.9140 | 0.6895 | 0.8053 | 0.9205 | 1.1475 | 0.9311 | 0.5401 | 1.3189 | 0.6540 | 1.3087 | 0.4630 |
| TESTOSTERONE | NA | NA | NA | NA | NA | 1.0575 | NA | NA | NA | 0.9425 | NA | NA | NA | NA |
| THYROTROPIN RELEASING HORMONE | NA | NA | 0.2858 | 0.3054 | NA | NA | NA | NA | NA | 1.6833 | 1.1417 | 1.6012 | 1.1288 | 0.8539 |
| THYROXINE | 0.9796 | 0.8678 | 1.0478 | 1.0329 | 0.5270 | 0.9092 | 0.8491 | 0.9573 | 0.9773 | 1.3229 | 1.2800 | 1.0847 | 1.0149 | 0.6189 |
| TRICOSANOIC ACID | 0.9421 | NA | 1.4453 | 1.1759 | 0.8120 | 0.6622 | NA | NA | NA | 0.8292 | NA | 0.8277 | 1.1297 | NA |
| TRYPTOPHAN | 1.0352 | 1.1501 | 1.0074 | 1.1765 | 0.7408 | 1.1563 | 0.9595 | 0.8887 | 0.9269 | 1.0541 | 0.9676 | 1.0959 | 0.9298 | 0.8480 |
| TRYPTOPHANAMIDE | NA | NA | NA | 1.0386 | NA | NA | NA | NA | NA | NA | NA | 1.0081 | NA | 0.9533 |
| URACIL | NA | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| URATE | 1.0017 | 1.1800 | 1.1280 | 1.0825 | 0.8502 | 1.0182 | 1.1397 | 0.8614 | 1.0672 | 0.9232 | 0.9731 | 0.9112 | 0.8839 | 1.2010 |
| URSODIOL | 0.9962 | 1.4647 | 2.5110 | 1.5057 | 1.3459 | 2.0440 | 2.0564 | NA | 0.2923 | 0.7217 | 0.8876 | 0.3239 | 0.3163 | NA |
| XANTHINE | 1.0876 | 1.1251 | 1.1884 | NA | 0.8107 | 0.9659 | 1.5558 | 1.0475 | 0.9686 | 0.9032 | 0.9714 | 0.9483 | 0.9137 | 0.8679 |
Factors:
| F1 | Group:Control | Visit:1 |
| F2 | Group:Control | Visit:2 |
| F3 | Group:Control | Visit:3 |
| F4 | Group:Control | Visit:4 |
| F5 | Group:Control | Visit:5 |
| F6 | Group:Control | Visit:6 |
| F7 | Group:Control | Visit:7 |
| F8 | Group:NAFLD | Visit:1 |
| F9 | Group:NAFLD | Visit:2 |
| F10 | Group:NAFLD | Visit:3 |
| F11 | Group:NAFLD | Visit:4 |
| F12 | Group:NAFLD | Visit:5 |
| F13 | Group:NAFLD | Visit:6 |
| F14 | Group:NAFLD | Visit:7 |
