Data for (Study ST000147)
(Analysis AN000233)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| 2 or 3-phosphoglycerate_13C_1 | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
| 2 or 3-phosphoglycerate_13C_2 | 1.3084 | 0.0095 | 1.6798 | 0.0217 | 0.0042 | NA | NA | NA |
| 2 or 3-phosphoglycerate_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA |
| 2 or 3-phosphoglycerate_2PG/3PG | 1.1351 | 0.0104 | 1.5650 | 0.0528 | 1.1183 | 0.0564 | 2.3883 | 0.1444 |
| 3-Glycerophosphate | 1.8744 | 0.0036 | 0.6075 | 0.0012 | 1.7417 | NA | 1.1069 | 0.0018 |
| 3-Glycerophosphate_13C_1 | 2.7116 | NA | 1.3355 | NA | 0.0855 | NA | 0.1998 | 0.0026 |
| 3-Glycerophosphate_13C_2 | 2.7990 | NA | 1.1947 | NA | 0.0034 | NA | 0.0028 | NA |
| 3-Glycerophosphate_13C_3 | 1.3523 | NA | 0.6477 | NA | NA | NA | NA | NA |
| 3-phosphoglyceraldehyde | 0.9011 | NA | 0.7816 | NA | 1.0736 | NA | 1.2438 | NA |
| 3-phosphoglyceraldehyde_13C_1 | 1.6350 | NA | 1.3486 | NA | 0.3088 | NA | 0.7076 | NA |
| 3-phosphoglyceraldehyde_13C_2 | 0.8410 | NA | 1.1590 | NA | NA | NA | NA | NA |
| 3-phosphoglyceraldehyde_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA |
| 6-Phosphogluconate | 1.1123 | NA | 1.9653 | NA | 0.3615 | NA | 0.5609 | NA |
| 6-Phosphogluconate_13C_1 | 1.2549 | NA | 1.4044 | NA | 0.6129 | NA | 0.7278 | NA |
| 6-Phosphogluconate_13C_2 | 1.1824 | NA | 1.3981 | NA | 0.5562 | NA | 0.8634 | NA |
| 6-Phosphogluconate_13C_3 | 0.9223 | NA | 0.6603 | NA | 0.7541 | NA | 1.6633 | NA |
| 6-Phosphogluconate_13C_4 | 0.5482 | NA | 0.4698 | NA | 0.9995 | NA | 1.9825 | NA |
| 6-Phosphogluconate_13C_5 | 0.6262 | NA | 0.1720 | NA | 0.9789 | NA | 1.6709 | NA |
| 6-Phosphogluconate_13C_6 | 0.1436 | NA | NA | NA | 0.7158 | NA | 2.4153 | 0.1758 |
| Acetyl-CoA | 0.4070 | NA | 0.7588 | NA | 1.2055 | NA | 1.6287 | NA |
| Acetyl-CoA_13C_1 | 1.8863 | NA | 1.8326 | NA | 0.1145 | NA | 0.1667 | NA |
| Acetyl-CoA_13C_2 | 0.8505 | NA | 0.9501 | NA | 0.6590 | NA | 1.5405 | NA |
| Adenosine diphosphate | 0.5713 | 0.0249 | 0.6951 | 0.0271 | 2.0024 | NA | 2.3550 | NA |
| Adenosine diphosphate_13C_1 | 2.2991 | NA | 1.4516 | NA | 0.0897 | NA | 0.1597 | NA |
| Adenosine diphosphate_13C_2 | 1.9842 | NA | 1.3202 | NA | 0.0262 | NA | 0.0080 | NA |
| Adenosine diphosphate_13C_3 | 1.1743 | NA | 0.8257 | NA | NA | NA | NA | NA |
| Adenosine diphosphate_13C_4 | 1.1418 | NA | 0.8582 | NA | NA | NA | NA | NA |
| Adenosine diphosphate_13C_5 | 0.7563 | NA | 1.6144 | NA | 0.4439 | NA | NA | NA |
| Adenosine monophosphate | 0.5415 | 0.3381 | 0.6100 | NA | 1.7862 | NA | 1.5921 | 0.0726 |
| Adenosine monophosphate_13C_1 | 2.3903 | 0.0853 | 1.6314 | NA | 0.1890 | NA | 0.0942 | NA |
| Adenosine monophosphate_13C_2 | 2.2950 | 0.0154 | 1.5985 | NA | 0.0343 | NA | 0.1005 | NA |
| Adenosine monophosphate_13C_3 | 1.5414 | 0.0470 | 1.0447 | NA | NA | NA | 0.1948 | NA |
| Adenosine monophosphate_13C_4 | 1.5982 | 0.0373 | 1.3757 | NA | 0.0205 | NA | NA | NA |
| Adenosine monophosphate_13C_5 | 1.5209 | NA | 1.4056 | NA | 0.0735 | NA | NA | NA |
| Adenosine triphosphate | 0.8677 | 0.0396 | 1.2930 | 0.0300 | 1.7186 | 0.0036 | 3.0572 | 0.0021 |
| Adenosine triphosphate_13C_1 | 2.3436 | 0.0016 | 1.8572 | NA | 0.0548 | NA | 0.0772 | NA |
| Adenosine triphosphate_13C_2 | 1.9705 | NA | 1.6597 | NA | 0.0179 | NA | 0.0280 | NA |
| Adenosine triphosphate_13C_3 | 1.8146 | NA | 1.5123 | 0.0080 | 0.0048 | NA | 0.0018 | NA |
| Adenosine triphosphate_13C_4 | 1.1778 | NA | 1.1552 | NA | 0.0011 | NA | NA | NA |
| Adenosine triphosphate_13C_5 | 0.6711 | NA | 1.3289 | NA | NA | NA | NA | NA |
| Aspartate | 0.3840 | 1.5559 | 0.8984 | 1.5832 | 0.1789 | 1.6887 | 0.3463 | 1.8385 |
| Aspartate_13C_1 | 1.3475 | 0.0624 | 1.8273 | 0.1753 | NA | NA | NA | NA |
| Aspartate_13C_2 | 1.3430 | 0.0488 | 2.4761 | 0.0851 | 0.9713 | 0.0926 | 2.2461 | 0.1482 |
| Aspartate_13C_3 | 0.9042 | NA | 0.8749 | NA | 0.9253 | 0.0656 | 2.7917 | 0.1574 |
| Aspartate_13C_4 | 0.1470 | NA | 0.1962 | NA | 1.0604 | 0.0210 | 4.1431 | 0.1484 |
| Citrate or Isocitrate | 1.7483 | 0.6900 | 2.2852 | 0.7716 | 0.7253 | 0.5492 | 0.8018 | 0.4287 |
| Citrate or Isocitrate_13C_1 | 2.0679 | 0.3306 | 1.3781 | 0.1973 | 1.5792 | 0.5461 | 1.5619 | 0.3388 |
| Citrate or Isocitrate_13C_2 | 2.6740 | 0.6922 | 2.1228 | 0.4606 | 0.6328 | 0.3290 | 0.8062 | 0.2824 |
| Citrate or Isocitrate_13C_3 | 1.3433 | 0.2175 | 0.6622 | 0.0854 | 1.6377 | 0.7306 | 2.5070 | 0.8162 |
| Citrate or Isocitrate_13C_4 | 1.5162 | 0.4016 | 0.8851 | 0.1867 | 0.9413 | 1.0266 | 1.7985 | 1.2439 |
| Citrate or Isocitrate_13C_5 | 0.1877 | 0.0674 | 0.0773 | 0.0223 | 1.5323 | 0.9321 | 3.6204 | 1.5604 |
| Citrate or Isocitrate_13C_6 | 0.5541 | 0.2729 | 0.3389 | 0.3114 | 1.1890 | 0.5680 | 3.5470 | 1.2187 |
| Erythrose 4-phosphate | 1.1268 | NA | 0.8116 | NA | 0.9537 | NA | 1.1080 | NA |
| Erythrose 4-phosphate_13C_1 | 0.8970 | NA | 1.2061 | NA | NA | NA | NA | NA |
| Erythrose 4-phosphate_13C_2 | 1.5231 | NA | 1.1398 | NA | NA | NA | 0.0056 | NA |
| Erythrose 4-phosphate_13C_3 | 0.3735 | NA | 1.6265 | NA | NA | NA | NA | NA |
| Erythrose 4-phosphate_13C_4 | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate | 1.0771 | 0.1578 | 0.4053 | 0.0273 | 3.1897 | 0.0178 | 2.1250 | NA |
| Fructose 1,6-bisphosphate_13C_1 | 2.4849 | NA | 0.9558 | NA | 0.1556 | NA | 0.1057 | NA |
| Fructose 1,6-bisphosphate_13C_2 | 4.5278 | 0.0171 | 2.3387 | 0.0155 | 0.0614 | 0.0117 | 0.0279 | NA |
| Fructose 1,6-bisphosphate_13C_3 | 1.8423 | 0.0190 | 0.4021 | 0.0520 | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate_13C_4 | 2.8712 | NA | 1.0993 | NA | 0.0270 | NA | 0.0025 | NA |
| Fructose 1,6-bisphosphate_13C_5 | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate_13C_6 | NA | 1.0000 | NA | NA | NA | NA | NA | NA |
| Glucose 6-phosphate or fructose-6-phosphate | 0.8273 | 0.1350 | 0.4798 | 0.0742 | 2.0806 | 0.0250 | 3.1320 | 0.0523 |
| Glucose 6-phosphate or fructose-6-phosphate_13C_1 | 2.0559 | 0.0323 | 1.7704 | NA | 0.2342 | NA | 0.2621 | NA |
| Glucose 6-phosphate or fructose-6-phosphate_13C_2 | 2.1967 | 0.0456 | 2.0359 | NA | 0.0595 | NA | 0.0261 | NA |
| Glucose 6-phosphate or fructose-6-phosphate_13C_3 | 1.3806 | NA | 0.9355 | NA | NA | NA | 0.0516 | NA |
| Glucose 6-phosphate or fructose-6-phosphate_13C_4 | 1.6350 | NA | 1.0134 | NA | 0.0261 | NA | 0.0285 | NA |
| Glucose 6-phosphate or fructose-6-phosphate_13C_5 | 0.9380 | NA | 1.0620 | NA | NA | NA | NA | NA |
| Glucose 6-phosphate or fructose-6-phosphate_13C_6 | 1.2885 | NA | 0.7115 | NA | NA | NA | NA | NA |
| Glutamate | 2.7473 | 0.3251 | 2.8079 | 0.2657 | 0.7351 | 0.2891 | 0.6193 | 0.2107 |
| Glutamate_13C_1 | 2.7868 | 0.0403 | 1.3678 | 0.0342 | 1.9723 | 0.0524 | 1.3823 | 0.0457 |
| Glutamate_13C_2 | 3.9718 | 0.0421 | 2.4949 | 0.0325 | 0.7357 | 0.0240 | 0.6797 | 0.0194 |
| Glutamate_13C_3 | 1.7145 | 0.0164 | 0.6658 | 0.0060 | 2.5369 | 0.0823 | 2.8843 | 0.0937 |
| Glutamate_13C_4 | 3.1045 | 0.0379 | 1.5502 | 0.0254 | 0.7625 | NA | 1.1434 | 0.0511 |
| Glutamate_13C_5 | 0.1313 | 0.0028 | 0.0439 | 0.0004 | 2.6905 | 0.1479 | 4.3718 | 0.2782 |
| Lactate | NA | NA | NA | NA | NA | NA | NA | NA |
| Lactate_13C_1 | NA | NA | NA | NA | NA | NA | NA | NA |
| Lactate_13C_2 | NA | NA | NA | NA | NA | NA | NA | NA |
| Lactate_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA |
| Malate | 2.5928 | 0.0149 | 3.4459 | 0.0226 | 0.8632 | 0.0072 | 1.0442 | 0.0092 |
| Malate_13C_1 | 2.0227 | 0.0022 | 1.3008 | 0.0008 | 1.1203 | 0.0003 | 1.2215 | NA |
| Malate_13C_2 | 2.4979 | 0.0045 | 2.2509 | 0.0036 | 1.1687 | 0.0016 | 1.7379 | 0.0021 |
| Malate_13C_3 | 1.8141 | 0.0061 | 0.9692 | 0.0089 | 1.8123 | 0.0218 | 3.3439 | 0.0238 |
| Malate_13C_4 | 0.3086 | 0.0168 | 0.2104 | 0.0139 | 2.1224 | 0.0247 | 4.6142 | 0.0336 |
| Malonyl-CoA | 0.5552 | NA | 0.9059 | NA | 1.0654 | NA | 1.4735 | NA |
| Malonyl-CoA_13C_1 | 1.5384 | NA | 1.6801 | NA | 0.0402 | NA | 0.1320 | NA |
| Malonyl-CoA_13C_2 | 0.9301 | NA | 1.2746 | NA | 0.5209 | NA | 1.2744 | NA |
| Malonyl-CoA_13C_3 | 1.2264 | NA | 1.3826 | NA | 0.0130 | NA | 0.1599 | NA |
| Nicotinamide Adenine Dinucleotide oxidized | 0.3987 | NA | 0.2242 | NA | 1.7617 | NA | 1.6155 | NA |
| Nicotinamide Adenine Dinucleotide oxidized_13C_1 | 2.1398 | NA | 1.5946 | NA | 0.1418 | NA | 0.1238 | NA |
| Nicotinamide Adenine Dinucleotide oxidized_13C_2 | 2.4963 | NA | 1.4483 | NA | 0.0167 | NA | 0.0387 | NA |
| Nicotinamide Adenine Dinucleotide oxidized_13C_3 | 2.2019 | NA | 1.4519 | NA | 0.0015 | NA | 0.0119 | NA |
| Nicotinamide Adenine Dinucleotide oxidized_13C_4 | 1.4288 | NA | 0.9041 | NA | 0.0012 | NA | NA | NA |
| Nicotinamide Adenine Dinucleotide oxidized_13C_5 | 1.2531 | NA | 0.7469 | NA | NA | NA | NA | NA |
| Nicotinamide Adenine Dinucleotide reduced | 0.4933 | NA | 0.2013 | NA | 2.0017 | NA | 1.3037 | NA |
| Nicotinamide Adenine Dinucleotide reduced_13C_1 | 2.1341 | NA | 1.1421 | NA | 0.0358 | NA | 0.0641 | NA |
| Nicotinamide Adenine Dinucleotide reduced_13C_2 | 2.7030 | NA | 1.2377 | NA | 0.0203 | NA | 0.0389 | NA |
| Nicotinamide Adenine Dinucleotide reduced_13C_3 | 2.7078 | NA | 1.2535 | NA | 0.0126 | NA | 0.0260 | NA |
| Nicotinamide Adenine Dinucleotide reduced_13C_4 | 2.0146 | NA | 0.9825 | NA | 0.0019 | NA | 0.0047 | NA |
| Nicotinamide Adenine Dinucleotide reduced_13C_5 | 2.2944 | NA | 1.0357 | NA | 0.0025 | NA | 0.0021 | NA |
| Phosphoenolpyruvate | 1.1391 | NA | 1.0484 | NA | 0.4004 | NA | 1.4121 | NA |
| Phosphoenolpyruvate_13C_1 | 1.4653 | NA | 0.3020 | NA | NA | NA | NA | NA |
| Phosphoenolpyruvate_13C_2 | NA | NA | NA | NA | NA | NA | NA | NA |
| Phosphoenolpyruvate_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA |
| Ribose-5-phosphate or xylulose 5-phosphate | NA | 0.0577 | NA | 0.1761 | 3.1328 | 0.0565 | 1.7735 | 0.2931 |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_1 | 3.0551 | 0.0228 | 1.2004 | NA | 0.0153 | NA | 0.0525 | NA |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_2 | 3.5519 | NA | 0.1494 | NA | NA | NA | NA | NA |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_3 | 1.4214 | NA | 0.5786 | NA | NA | NA | NA | NA |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_4 | 1.4566 | NA | 0.5434 | NA | NA | NA | NA | NA |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_5 | 1.4293 | NA | 0.5707 | NA | NA | NA | NA | NA |
| Sedoheptulose 7-phosphate | 0.9463 | NA | 0.3920 | NA | 1.4522 | NA | 1.2095 | NA |
| Sedoheptulose 7-phosphate_13C_1 | 1.6092 | NA | NA | NA | 0.0861 | NA | NA | NA |
| Sedoheptulose 7-phosphate_13C_2 | 1.5101 | NA | 0.8229 | NA | 0.0008 | NA | NA | NA |
| Sedoheptulose 7-phosphate_13C_3 | 1.4682 | NA | 0.8567 | NA | NA | NA | 0.0253 | NA |
| Sedoheptulose 7-phosphate_13C_4 | 1.2724 | NA | 0.7276 | NA | NA | NA | NA | NA |
| Sedoheptulose 7-phosphate_13C_5 | 1.2996 | NA | 0.7004 | NA | NA | NA | NA | NA |
| Sedoheptulose 7-phosphate_13C_6 | 1.7783 | NA | 0.2217 | NA | NA | NA | NA | NA |
| Sedoheptulose 7-phosphate_13C_7 | 1.8029 | NA | 0.1971 | NA | NA | NA | NA | NA |
| Sucrose | 0.1172 | 0.3494 | 3.7781 | 0.1062 | 0.0184 | NA | 0.2825 | 0.0915 |
| Sucrose_13C_1 | 0.0996 | 0.0230 | NA | NA | 0.2113 | NA | 2.1499 | 1.7935 |
| Sucrose_13C_2 | NA | NA | 1.8583 | NA | 0.3601 | NA | 0.3448 | NA |
| Sucrose_13C_3 | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
| Sucrose_13C_4 | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
Factors:
| F1 | Treatment:13C glucose labeled | Cell type:Cloned Jurkat cell mid level Noxa | Harvest:cells |
| F2 | Treatment:13C glucose labeled | Cell type:Cloned Jurkat cell mid level Noxa | Harvest:spent medium |
| F3 | Treatment:13C glucose labeled | Cell type:Noxa overexpressed Jurkat cell | Harvest:cells |
| F4 | Treatment:13C glucose labeled | Cell type:Noxa overexpressed Jurkat cell | Harvest:spent medium |
| F5 | Treatment:13C glutamine labeled | Cell type:Cloned Jurkat cell mid level Noxa | Harvest:cells |
| F6 | Treatment:13C glutamine labeled | Cell type:Cloned Jurkat cell mid level Noxa | Harvest:spent medium |
| F7 | Treatment:13C glutamine labeled | Cell type:Noxa overexpressed Jurkat cell | Harvest:cells |
| F8 | Treatment:13C glutamine labeled | Cell type:Noxa overexpressed Jurkat cell | Harvest:spent medium |
