Data for (Study ST000514)
(Analysis AN000787)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1-Methylhistidine | NA | 1.2222 | NA | NA | 0.7778 | NA | NA | NA | NA | NA | NA | NA |
| 3-Methylhistidine | 0.9380 | 1.8135 | 1.0631 | 0.5420 | 1.0840 | 1.5287 | 1.5217 | 0.7348 | 0.7713 | 0.8755 | 0.9311 | 0.8095 |
| Alanine | 0.9316 | 1.3835 | 0.8457 | 0.7732 | 0.9027 | 1.1625 | 0.7055 | 1.0014 | 1.3404 | 1.4276 | 0.7567 | 0.8984 |
| allo-Isoleucine | NA | NA | NA | NA | 1.3929 | NA | NA | 0.4286 | NA | NA | 0.8571 | 1.0714 |
| alpha-Aminoadipic-acid | 0.8408 | 1.0068 | 1.3387 | 0.4093 | 0.9957 | 0.6011 | 1.1506 | 1.2861 | 1.1616 | 1.4493 | 0.8906 | 0.9146 |
| alpha-Amino-N-butyric-acid | 0.3940 | 0.6317 | 0.2752 | 0.4503 | 0.4628 | 0.4753 | 0.5754 | 1.1414 | 0.3878 | 4.8784 | 0.3711 | 0.3919 |
| Anserine | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Arginine | 1.3430 | 1.2197 | 1.2076 | 0.6578 | 1.2864 | 1.0153 | 0.7443 | 0.7405 | 0.7335 | 0.8935 | 0.9876 | 0.9131 |
| Asparagine | 0.8905 | 1.2114 | 0.8177 | 0.9697 | 0.8839 | 1.1282 | 0.7633 | 1.0917 | 1.1714 | 1.3566 | 0.8225 | 0.9215 |
| Aspartic Acid | 1.3774 | 0.7702 | 1.3527 | 1.1454 | 0.8886 | 0.8919 | 0.7307 | 0.8467 | 0.9183 | 1.1750 | 0.9314 | 0.9643 |
| beta-alanine | 1.6728 | 2.6765 | 0.6176 | 1.0294 | 1.6814 | 1.1667 | 0.3088 | NA | 0.5147 | 0.1029 | 1.0637 | 0.8578 |
| beta-Aminoisobutyric-acid | NA | 1.0000 | NA | NA | NA | 1.0000 | NA | NA | NA | 1.0000 | NA | NA |
| Carnosine | NA | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA | NA | NA |
| Citrulline | 1.2492 | 1.5332 | 0.9374 | 1.0576 | 1.0262 | 1.1389 | 0.7806 | 0.9025 | 1.0750 | 1.2388 | 0.8087 | 0.6955 |
| Cystathionine 1 | 1.5450 | 2.2561 | 0.8338 | 0.3433 | 1.2098 | 0.9646 | 1.5695 | 0.7480 | 0.5395 | 1.2139 | 0.6540 | 0.6213 |
| Cystathionine 2 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Cystine | 0.9101 | 2.0461 | 1.7512 | 0.1843 | 0.8879 | 0.9186 | 0.6544 | 1.0968 | 1.4747 | 0.8917 | 0.9724 | 0.8326 |
| Ethanolamine | 1.0506 | 1.0335 | 0.8829 | 1.3483 | 0.7962 | 1.2821 | 1.1087 | 1.0437 | 1.3757 | 1.3568 | 0.7779 | 0.7517 |
| gamma-Amino-N-butyric-acid | 0.9419 | 0.8372 | 0.8372 | 5.0233 | 0.5581 | 1.9535 | 0.4186 | 1.0465 | 0.8372 | 1.0465 | 0.6977 | 0.5581 |
| Glutamic Acid | 1.3037 | 0.7428 | 1.2852 | 1.1719 | 1.0521 | 0.8590 | 0.8604 | 0.7504 | 0.7254 | 1.2569 | 1.0162 | 0.8996 |
| Glutamine | 0.9153 | 1.1070 | 1.0156 | 1.1008 | 0.8293 | 0.9494 | 0.8898 | 1.1473 | 1.1605 | 1.3090 | 0.8845 | 0.9149 |
| Glycine | 0.9647 | 1.1204 | 0.8809 | 1.0233 | 1.1448 | 1.2410 | 0.8961 | 0.7182 | 1.1334 | 0.7185 | 1.0512 | 1.1258 |
| Histidine | 0.9260 | 0.7996 | 1.0607 | 1.0904 | 1.1917 | 1.5475 | 0.7302 | 0.6377 | 0.8690 | 1.1367 | 0.8338 | 1.1047 |
| Homocystine | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Hydroxylysine 1 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Hydroxylysine 2 | 0.7712 | 0.8814 | 1.3220 | 0.4407 | 2.1299 | 1.3220 | NA | NA | 0.2203 | NA | 0.6610 | 0.9181 |
| Hydroxyproline | 1.1742 | 1.1962 | 1.3536 | 0.7681 | 1.0556 | 1.1291 | 0.5855 | 0.5525 | 0.8499 | 0.9271 | 1.0504 | 1.0965 |
| Lysine | 0.9754 | 1.0260 | 1.0399 | 0.5122 | 1.0782 | 0.8016 | 0.8793 | 0.8057 | 1.2886 | 1.2751 | 0.9594 | 1.1013 |
| Methionine | 1.1513 | 1.3903 | 1.1792 | 0.5292 | 1.3398 | 1.1333 | 0.7418 | 0.7043 | 0.9620 | 1.0121 | 0.8759 | 0.9437 |
| Ornithine | 0.9096 | 0.7748 | 1.0901 | 0.8603 | 1.2346 | 0.9377 | 0.5345 | 0.6142 | 1.0408 | 1.5425 | 0.9236 | 1.1002 |
| Phosphoethanolamine | 0.9742 | 0.7488 | 1.3813 | 1.0614 | 0.7851 | 0.9451 | 0.9742 | 1.0505 | 0.8724 | 1.2141 | 0.9790 | 1.0323 |
| Proline | 1.0895 | 1.4716 | 1.0315 | 0.7749 | 1.1850 | 1.2475 | 0.6339 | 0.7703 | 1.1258 | 1.1539 | 0.7950 | 0.8947 |
| Sarcosine | 1.3688 | 2.2243 | 0.5703 | 0.9125 | 1.4068 | 0.9506 | 0.2281 | 0.2281 | 0.3422 | 0.5703 | 0.9316 | 0.7605 |
| Serine | 0.8921 | 0.9770 | 0.9616 | 0.8490 | 0.9337 | 1.0085 | 0.9012 | 0.9903 | 1.1829 | 1.2383 | 0.9499 | 1.0237 |
| Taurine | 1.1384 | 0.9549 | 0.9913 | 0.8071 | 0.9123 | 0.8889 | 1.0486 | 1.0739 | 1.0955 | 1.5302 | 0.8551 | 0.7740 |
| Threonine | 0.9666 | 0.9857 | 1.0473 | 0.5262 | 1.1049 | 0.8205 | 1.0731 | 0.9867 | 1.2950 | 1.3377 | 0.8864 | 0.9713 |
| Tyrosine | 1.0363 | 1.1624 | 0.8945 | 1.0504 | 1.4167 | 1.3390 | 0.5278 | 0.6699 | 0.8055 | 1.0298 | 0.8509 | 1.0135 |
| Valine | 1.0475 | 1.0057 | 0.9077 | 0.7179 | 1.0057 | 0.9676 | 0.8354 | 0.9928 | 1.1686 | 1.2401 | 0.9598 | 0.9265 |
Factors:
| F1 | Group:Control colch | Genotype:Irlox IGFRlox | Treatment:Colch |
| F2 | Group:Control colch | Genotype:Irlox | Treatment:Colch |
| F3 | Group:Control colch | Genotype:- | Treatment:Colch |
| F4 | Group:control | Genotype:IR -/- IGFR -/- | Treatment:saline |
| F5 | Group:control | Genotype:Irlox IGFRlox | Treatment:saline |
| F6 | Group:control | Genotype:Irlox | Treatment:saline |
| F7 | Group:HFD + Colch | Genotype:Irlox IGFRlox | Treatment:Colch |
| F8 | Group:HFD + Colch | Genotype:Irlox | Treatment:Colch |
| F9 | Group:HFD | Genotype:Irlox IGFRlox | Treatment:saline |
| F10 | Group:HFD | Genotype:Irlox | Treatment:saline |
| F11 | Group:MIGIRKO colch | Genotype:IR -/- IGFR -/- | Treatment:Colch |
| F12 | Group:MIGIRKO | Genotype:IR -/- IGFR -/- | Treatment:saline |
