Data for (Study ST000567)
(Analysis AN000872)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|
| 1,25-Dihydroxyvitamin D3-26,23-lactone | 1.2222 | 1.6817 | 0.3101 | 0.5221 | NA | 1.0513 |
| 17beta-Methylestra-1,3,5(10)-trien-3-ol | 0.2996 | 0.5117 | 0.4674 | 0.8540 | NA | 2.9887 |
| 17-phenyl trinor Prostaglandin E2 serinol amide | 0.9723 | 0.8775 | 1.1030 | 1.1478 | NA | 0.9387 |
| 19-Hydroxy-8-O-methyltetrangulol | 1.1935 | 1.0207 | 1.2914 | 1.0955 | NA | 0.3959 |
| 19-Hydroxy-8-O-methyltetrangulol + 2.978841 | 1.2057 | 1.0209 | 1.2843 | 1.0487 | NA | 0.4319 |
| 1-Aminocyclohexanecarboxylic acid | 1.1933 | 0.7757 | 1.0775 | 0.8748 | NA | 1.0798 |
| 1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide | 1.0392 | 1.0457 | 1.1973 | 1.1765 | NA | 0.5558 |
| 27-Hydroxycholesterol | 1.5552 | 1.2050 | 0.6240 | 0.5998 | NA | 0.8519 |
| 2E-methyl-glutaconic acid | 1.0228 | 1.4061 | 0.6344 | 1.0639 | NA | 0.7900 |
| 2-Keto-6-aminocaproic acid | 1.1504 | 0.9479 | 1.1588 | 1.2448 | NA | 0.5129 |
| 2-Methylbutanal | 1.0909 | 1.0649 | 0.9854 | 1.0091 | NA | 0.8270 |
| 2^-O-Methyladenosine | 1.0552 | 1.0347 | 1.0347 | 1.0445 | NA | 0.8237 |
| 2-Oxo-7-methylthioheptanoic acid | 0.7035 | 0.9352 | 1.0844 | 1.1138 | NA | 1.2289 |
| 2S-amino-pentanoic acid | 1.1410 | 1.1914 | 0.8434 | 0.8600 | NA | 0.8956 |
| 3,4,5-Trimethoxycinnamic acid | 0.9591 | 1.0471 | 1.3676 | 1.4247 | NA | 0.2572 |
| 3,7-Dimethyl-2E,6-octadienyl acetate | 0.8972 | 1.0604 | 0.8925 | 1.3106 | NA | 0.8598 |
| 3-Dimethylallyl-4-hydroxyphenylpyruvate | 1.1140 | 1.1822 | 0.8728 | 1.1039 | NA | 0.6832 |
| 3-hydroxy-decanoic acid | 1.1069 | 1.0865 | 0.8584 | 1.0688 | NA | 0.8466 |
| 4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3-ol | 1.1739 | 1.0669 | 1.8993 | 0.4517 | NA | 0.3989 |
| 4-Dodecylphenol | 0.8347 | 0.8872 | 1.3096 | 1.3666 | NA | 0.6900 |
| 4-Hydroxy-6-methylpyran-2-one | 1.1773 | 0.8378 | 1.2166 | 1.0692 | NA | 0.7173 |
| 4^-O-Methylisoflavone | 0.8743 | 1.1265 | 0.8598 | 0.8762 | NA | 1.2442 |
| 4-Oxoproline | 1.0370 | 1.0520 | 0.9884 | 0.9437 | NA | 0.9614 |
| 5-(3-Pyridyl)-2-hydroxytetrahydrofuran | 1.3583 | 1.2691 | 0.9892 | 1.1277 | NA | 0.1745 |
| 5alpha-Cholestan-5alpha,6beta-diol | 1.0262 | 1.0776 | 1.1245 | 1.0513 | NA | 0.7181 |
| 5-Methylthio-D-ribose | 1.0672 | 1.0417 | 1.0435 | 1.0819 | NA | 0.7591 |
| 6-Benzylaminopurine | 0.8473 | 0.8617 | 1.1212 | 0.9124 | NA | 1.3014 |
| 6-endo-Hydroxycineole | 0.8657 | 0.9122 | 0.9447 | 1.1653 | NA | 1.1517 |
| 6-methyltetrahydropterin | 1.0004 | 0.9615 | 0.8866 | 0.9519 | NA | 1.1935 |
| 7?-Hydroxy-3-oxo-4-cholestenoate | 1.0055 | 1.0627 | 0.9043 | 0.9395 | NA | 1.0672 |
| 7-Methylguanine | 1.2686 | 1.0810 | 0.9859 | 0.9882 | NA | 0.6246 |
| 8Z,11Z,14Z-heptadecatrienoic acid | 1.0681 | 1.4054 | 0.6079 | 0.6514 | NA | 1.1465 |
| 9,10-dihydroxy stearic acid | 0.8307 | 0.8742 | 1.3386 | 1.3677 | NA | 0.6815 |
| 9-Hydroxyphenanthrene | 0.9198 | 0.9588 | 1.0683 | 0.9762 | NA | 1.0974 |
| 9S,11R,15S-trihydroxy-2,3-dinor-13E-prostaenoic acid-cyclo[8S,12R] | 0.9029 | 0.9953 | 1.2602 | 1.4629 | NA | 0.4448 |
| 9S,12S,13S-trihydroxy-10E-octadecenoic acid | 0.8863 | 1.5160 | 1.1428 | 1.0582 | NA | 0.3536 |
| 9(S)-HpOTrE | 1.0294 | 0.9341 | 1.1700 | 1.2943 | NA | 0.6105 |
| ADMA | 1.0721 | 0.8628 | 1.2755 | 1.1386 | NA | 0.6898 |
| ?-Alanine | 0.9848 | 0.8522 | 0.7576 | 1.0201 | NA | 1.3927 |
| Alpha-N-Phenylacetyl-L-glutamine | 1.0607 | 1.0877 | 1.1656 | 1.3338 | NA | 0.3666 |
| Anthranilic acid | 1.2070 | 1.2893 | 1.0533 | 0.9345 | NA | 0.4441 |
| Artemisin | 1.0759 | 1.4862 | 1.0167 | 0.9551 | NA | 0.3838 |
| Astrasieversianin XVI | 0.9862 | 1.2204 | 0.9344 | 0.9617 | NA | 0.8604 |
| Bilirubin | 1.0345 | 1.1778 | 0.8712 | 1.0283 | NA | 0.8507 |
| Buprenorphine | 0.9256 | 0.8664 | 1.0303 | 1.0451 | NA | 1.1677 |
| Butyl acrylate | 1.0188 | 1.0133 | 1.0492 | 1.0657 | NA | 0.8566 |
| Caffeine | 1.1953 | 1.1502 | 1.0616 | 1.3508 | NA | 0.2222 |
| Caproic acid | 1.0617 | 1.2658 | 0.8827 | 0.8096 | NA | 0.9116 |
| Carbaryl | 0.7369 | 0.7856 | 1.6270 | 1.3829 | NA | 0.6080 |
| Carboxynorspermidine | 1.0587 | 1.0766 | 0.9593 | 0.9516 | NA | 0.9280 |
| CE(20:4) | 0.9820 | 1.1393 | 1.0405 | 0.7427 | NA | 1.0626 |
| Ceramide (d18:1/24:1(15Z)) | 0.9326 | 0.9130 | 0.7383 | 1.0854 | NA | 1.3402 |
| Chalepensin | 0.8188 | 1.0185 | 1.0095 | 0.9690 | NA | 1.2058 |
| Chenodeoxycholic acid sulfate | 1.2653 | 1.2128 | 0.7480 | 1.0220 | NA | 0.6672 |
| cis-9,10-Epoxystearic acid | 0.7865 | 0.8520 | 1.5115 | 1.3996 | NA | 0.5671 |
| Coenzyme Q10 | 0.9756 | 1.1271 | 1.0433 | 1.5028 | NA | 0.3756 |
| Concanamycin A | 0.9466 | 0.8097 | 1.6101 | 1.0329 | NA | 0.6815 |
| Creatinine | 1.0249 | 1.0164 | 1.0390 | 1.0605 | NA | 0.8605 |
| Cycloleucine | 1.1338 | 1.2571 | 0.8676 | 1.0976 | NA | 0.5855 |
| Cyperine | 0.6668 | 0.7886 | 0.7960 | 0.8996 | NA | 1.9050 |
| D-2-Amino-hexano-6-lactam | 0.9533 | 0.9867 | 0.9448 | 0.9578 | NA | 1.1590 |
| Debneyol | 1.1523 | 0.7751 | 1.4132 | 0.9876 | NA | 0.7109 |
| Decylubiquinol | 1.0586 | 1.3585 | 0.9656 | 1.0593 | NA | 0.5001 |
| delta-Guanidinovaleric acid | 1.4220 | 1.0509 | 1.3737 | 1.0234 | NA | 0.0908 |
| DG(22:4(7Z,10Z,13Z,16Z)/22:2(13Z,16Z)/0:0) | 1.0016 | 1.0389 | 0.9673 | 0.9217 | NA | 1.0567 |
| DG(22:4(7Z,10Z,13Z,16Z)/22:2(13Z,16Z)/0:0) + 1.1061205 | 1.0910 | 0.9840 | 0.8412 | 0.9597 | NA | 1.0993 |
| DG(22:5(7Z,10Z,13Z,16Z,19Z)/22:4(7Z,10Z,13Z,16Z)/0:0) | 0.9149 | 0.9007 | 1.0577 | 0.8165 | NA | 1.3275 |
| DL-2-Aminooctanoic acid | 1.0719 | 1.0206 | 1.0954 | 1.1110 | NA | 0.7028 |
| DL-pipecolic acid | 1.0473 | 0.9868 | 0.9707 | 0.7792 | NA | 1.1934 |
| Docosanoic acid | 0.9791 | 1.0332 | 0.9555 | 0.9431 | NA | 1.0800 |
| D-Proline | 0.9779 | 0.9400 | 0.9095 | 0.8919 | NA | 1.2782 |
| D-Proline + 6.721675 | 0.8494 | 1.0465 | 1.0202 | 0.7328 | NA | 1.3484 |
| (E)-2-Butenyl-4-methyl-threonine | 1.0563 | 1.1814 | 1.2460 | 1.1792 | NA | 0.3336 |
| Gabapentin | 1.2024 | 1.1258 | 0.9211 | 0.7117 | NA | 0.9659 |
| Galabiosylceramide (d18:1/16:0) | 0.7136 | 1.0735 | 1.2251 | 0.6942 | NA | 1.3184 |
| HBA | 1.0889 | 1.1163 | 0.9474 | 0.9611 | NA | 0.8505 |
| Indoleacrylic acid | 0.9684 | 0.9627 | 0.9916 | 0.9338 | NA | 1.1480 |
| Isopentenyladenine | 1.1591 | 1.1968 | 0.9683 | 1.0173 | NA | 0.6067 |
| Lamivudine | 1.2163 | 1.0174 | 0.8291 | 1.1192 | NA | 0.7810 |
| Linoleic acid | 0.8537 | 0.8895 | 1.3203 | 1.3585 | NA | 0.6631 |
| L-Isoleucine | 1.0557 | 1.3965 | 1.4328 | 0.8689 | NA | 0.2030 |
| L-isoleucyl-L-proline | 1.0782 | 1.0292 | 1.1115 | 1.0619 | NA | 0.7161 |
| L-prolyl-L-glycine | 0.9729 | 0.9583 | 0.9621 | 0.9474 | NA | 1.1627 |
| MG(0:0/22:2(13Z,16Z)/0:0) | 0.9987 | 1.1417 | 1.0201 | 1.1397 | NA | 0.6911 |
| MG(18:0/0:0/0:0) | 1.0049 | 1.0770 | 0.9741 | 0.9223 | NA | 1.0026 |
| Muramic acid | 0.5871 | 0.8319 | 1.0844 | 1.0706 | NA | 1.5199 |
| N1-Acetylspermidine | 1.1985 | 1.2120 | 1.0951 | 0.7632 | NA | 0.6625 |
| N(alpha)-t-Butoxycarbonyl-L-leucine | 0.9958 | 1.0062 | 1.1056 | 1.0761 | NA | 0.8290 |
| Naltrexone | 1.0816 | 1.1408 | 1.0243 | 1.0013 | NA | 0.7221 |
| Neomenthyl acetate | 0.8391 | 0.9020 | 1.2948 | 1.3569 | NA | 0.6907 |
| Otonecine | 1.0424 | 1.0309 | 1.0628 | 1.0419 | NA | 0.8189 |
| Otonecine + 7.3512187 | 1.1155 | 1.0857 | 1.0219 | 0.9582 | NA | 0.7885 |
| Otonecine + 7.909625 | 1.0098 | 1.0939 | 0.8166 | 0.7872 | NA | 1.2495 |
| PE(20:2(11Z,14Z)/18:2(9Z,12Z)) | 1.0486 | 1.1930 | 1.0393 | 0.8505 | NA | 0.8262 |
| PE(20:3(5Z,8Z,11Z)/18:3(6Z,9Z,12Z)) | 1.0569 | 1.0824 | 1.0722 | 1.0006 | NA | 0.7732 |
| PE(20:4(8Z,11Z,14Z,17Z)/P-18:1(9Z)) | 1.0295 | 0.9502 | 1.0736 | 1.1898 | NA | 0.7786 |
| PE(20:5(5Z,8Z,11Z,14Z,17Z)/P-18:1(9Z)) | 0.9294 | 1.0501 | 1.3130 | 1.0616 | NA | 0.6757 |
| PE(22:2(13Z,16Z)/15:0) | 0.9839 | 1.0031 | 1.0112 | 0.9260 | NA | 1.0732 |
| PE(22:5(7Z,10Z,13Z,16Z,19Z)/P-18:1(11Z)) | 0.9864 | 1.0931 | 1.1909 | 1.0105 | NA | 0.7221 |
| PE(22:5(7Z,10Z,13Z,16Z,19Z)/P-18:1(11Z)) + 6.065796 | 1.0211 | 1.0491 | 1.1374 | 1.0961 | NA | 0.7031 |
| PE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/20:1(11Z)) | 1.1321 | 0.8014 | 1.2785 | 1.1718 | NA | 0.6578 |
| PE(22:6(4Z,7Z,10Z,13Z,16Z,19Z)/P-18:1(11Z)) | 1.0266 | 1.0958 | 1.1539 | 1.1375 | NA | 0.5894 |
| PG(18:1(11Z)/20:3(5Z,8Z,11Z)) | 0.9867 | 1.2910 | 1.3888 | 0.8234 | NA | 0.4855 |
| Phenanthrene-4,5-dicarboxylate | 1.0662 | 1.0146 | 1.1105 | 1.0756 | NA | 0.7348 |
| Phenanthrene-4,5-dicarboxylate + 3.291146 | 0.1804 | 0.7129 | 0.2788 | 0.7259 | NA | 3.1890 |
| Phytol | 0.9851 | 0.8426 | 1.0283 | 0.9162 | NA | 1.2484 |
| PI(20:3(5Z,8Z,11Z)/18:1(11Z)) | 1.0360 | 1.1502 | 0.9927 | 0.9459 | NA | 0.8442 |
| Piperidione | 1.0896 | 1.1071 | 0.9533 | 0.9319 | NA | 0.8818 |
| (S)-Coclaurine | 1.0739 | 1.2656 | 0.9140 | 1.0404 | NA | 0.6544 |
| Sphingosine | 0.9799 | 1.1342 | 0.9091 | 1.1976 | NA | 0.7705 |
| (S)-Scoulerine | 1.0458 | 1.0231 | 1.0206 | 0.9695 | NA | 0.9304 |
| TG(16:0/14:0/16:1(9Z))[iso6] | 0.8223 | 0.3356 | 0.8254 | 0.8016 | NA | 2.3088 |
| TG(16:1(9Z)/14:0/16:1(9Z))[iso3] | 0.7359 | 0.5669 | 0.9739 | 0.8522 | NA | 1.9583 |
| TG(16:1(9Z)/14:0/18:2(9Z,12Z))[iso6] | 0.9095 | 0.7892 | 0.8379 | 0.7576 | NA | 1.7200 |
| TG(16:1(9Z)/16:0/18:3(9Z,12Z,15Z))[iso6] | 0.9192 | 0.9722 | 0.9531 | 0.7177 | NA | 1.4298 |
| TG(18:1(9Z)/14:0/20:4(5Z,8Z,11Z,14Z))[iso6] | 0.8858 | 1.1790 | 0.9630 | 0.6970 | NA | 1.2416 |
| TG(18:2(9Z,12Z)/16:0/22:5(7Z,10Z,13Z,16Z,19Z))[iso6] | 0.7911 | 0.8687 | 1.1784 | 0.9328 | NA | 1.2855 |
| TG(18:2(9Z,12Z)/18:1(9Z)/18:3(6Z,9Z,12Z))[iso6] | 0.9379 | 1.1192 | 0.9535 | 0.6607 | NA | 1.2929 |
| TG(20:4(5Z,8Z,11Z,14Z)/14:0/18:3(9Z,12Z,15Z))[iso6] | 1.1134 | 0.9510 | 1.0637 | 0.7315 | NA | 1.1166 |
| TG(8:0/8:0/8:0) | 0.9469 | 0.5322 | 0.8026 | 1.4188 | NA | 1.3897 |
| Tolmetin | 0.9823 | 0.7896 | 1.0342 | 0.9966 | NA | 1.2320 |
| (+)-trans-alpha-Irone | 1.0893 | 1.0398 | 1.0100 | 1.0801 | NA | 0.7688 |
| trans-Zeatin | 0.9628 | 1.0234 | 1.2388 | 1.3147 | NA | 0.5017 |
| Tussilagine | 1.0556 | 1.0175 | 1.0476 | 1.1226 | NA | 0.7584 |
| Uridine | 1.1171 | 0.9490 | 1.0723 | 1.1144 | NA | 0.7510 |
| Uridine + 2.294484 | 1.0671 | 1.0427 | 1.0531 | 1.0541 | NA | 0.7750 |
| Valine | 1.0608 | 1.0917 | 0.9359 | 0.9465 | NA | 0.9350 |
Factors:
| F1 | groups:Old-Curcumin | Time point:Post |
| F2 | groups:Old-Curcumin | Time point:Pre |
| F3 | groups:Old-Placebo | Time point:Post |
| F4 | groups:Old-Placebo | Time point:Pre |
| F5 | groups:young | Time point:Baseline |
| F6 | groups:young | Time point:Pre |
