Data for (Study ST000824)
(Analysis AN001310)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| 6-PHOSPHOGLUCONIC ACID | 1.7805 | 1.3622 | 0.5652 | 0.4890 | 1.4922 | 0.4160 | 0.3375 | 1.3364 |
| ACETOACETYL-COA | 1.0292 | 0.9776 | 1.1493 | 0.9215 | 1.1894 | 1.3091 | 0.5821 | 0.7026 |
| ADENOSINE 5^-DIPHOSPHATE | 1.6753 | 1.7856 | 0.8046 | 0.7847 | 0.8295 | 0.6837 | 0.4290 | 0.8172 |
| ADENOSINE 5^-MONOPHOSPHATE | 1.9365 | 1.6126 | 0.4866 | 0.4602 | 1.8592 | 0.8728 | 0.1817 | 0.3177 |
| ADENOSINE TRIPHOSPHATE | 1.1596 | 1.3159 | 1.4438 | 1.3044 | 0.3195 | 0.5480 | 0.8300 | 1.0220 |
| BETA-NAD+ | 1.4589 | 1.9033 | 1.0135 | 0.9761 | 0.6349 | 0.4326 | 0.6335 | 0.8251 |
| CITRIC ACID | 1.1265 | 1.2078 | 0.8043 | 0.9213 | 0.9384 | 0.3478 | 0.8369 | 1.7628 |
| COENZYME II | 1.0647 | 0.9994 | 1.1139 | 0.8657 | 1.2553 | 1.1102 | 0.6276 | 0.8391 |
| D-ERYTHROSE 4-PHOSPHATE | 1.9983 | 1.7811 | 0.6699 | 0.5906 | 1.1087 | 0.3352 | 0.3020 | 0.9816 |
| D-FRUCTOSE, 1,6-BIS(DIHYDROGEN PHOSPHATE) | 0.2628 | 0.4786 | 2.5440 | 1.5162 | 0.4622 | 0.4663 | 0.4615 | 1.6289 |
| FAD | 0.9427 | 1.0967 | 0.7554 | 0.8836 | 1.9462 | 0.1377 | 0.6825 | 1.5053 |
| GLYCERATE 3-PHOSPHATE | 0.4942 | 0.6079 | 2.3668 | 1.3695 | 0.7206 | 0.5968 | 0.3799 | 1.2576 |
| MALIC ACID | 0.9562 | 1.2281 | 0.7467 | 0.4443 | 1.4330 | 0.8938 | 1.2305 | 0.8082 |
| NADH | 0.7827 | 1.3106 | 0.9813 | 1.9053 | 0.3772 | 0.2704 | 0.6089 | 1.1825 |
| NADP-REDUCED | 1.5808 | 1.6712 | 1.1490 | 1.4057 | 0.2659 | 0.2888 | 0.2518 | 0.6556 |
| PHOSPHOENOLPYRUVATE | 1.0222 | 1.2123 | 1.1646 | 1.1587 | 0.8762 | 0.9098 | 0.4577 | 1.0177 |
| RIBOSE PHOSPHATE | 0.9487 | 0.8150 | 1.2457 | 1.1283 | 1.5001 | 0.6292 | 0.4262 | 1.1586 |
| ROBISON ESTER | 1.9909 | 1.7409 | 0.6619 | 0.6190 | 1.0421 | 0.4119 | 0.3314 | 0.9791 |
| SEDOHEPTULOSE 7-PHOSPHATE | 1.8004 | 2.0246 | 0.8678 | 0.7182 | 0.6606 | 0.3656 | 0.3570 | 0.9914 |
| SUCROSE | 1.0922 | 1.4996 | 0.9872 | 0.9344 | 0.7826 | 0.6007 | 0.7846 | 1.2470 |
Factors:
| F1 | Cell line:MGG8 | IDH1-R132H EXPRESSION:NO | IDH1-R132H INHIBITOR:NO |
| F2 | Cell line:MGG8 | IDH1-R132H EXPRESSION:NO | IDH1-R132H INHIBITOR:YES |
| F3 | Cell line:MGG8 | IDH1-R132H EXPRESSION:YES | IDH1-R132H INHIBITOR:NO |
| F4 | Cell line:MGG8 | IDH1-R132H EXPRESSION:YES | IDH1-R132H INHIBITOR:YES |
| F5 | Cell line:SJGBM2 | IDH1-R132H EXPRESSION:NO | IDH1-R132H INHIBITOR:NO |
| F6 | Cell line:SJGBM2 | IDH1-R132H EXPRESSION:NO | IDH1-R132H INHIBITOR:YES |
| F7 | Cell line:SJGBM2 | IDH1-R132H EXPRESSION:YES | IDH1-R132H INHIBITOR:NO |
| F8 | Cell line:SJGBM2 | IDH1-R132H EXPRESSION:YES | IDH1-R132H INHIBITOR:YES |
