Data for (Study ST000844)
(Analysis AN001366)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 |
|---|---|---|---|---|---|---|---|---|---|
| 11_12-DiHETrE | 1.1278 | 0.9019 | 0.6414 | 1.3702 | 1.0094 | 0.9438 | 1.3265 | 1.1370 | 0.8709 |
| 11(12)-EpETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 11(12)-EpETrE | 0.8561 | 1.5047 | 0.4825 | 1.0118 | 1.0377 | 1.6344 | 0.7264 | 0.8042 | 0.7783 |
| 11-HETE | 1.6845 | 0.8955 | 0.8538 | 1.2908 | 0.3922 | 0.7411 | 1.5440 | 0.7164 | 0.4478 |
| 12_13-DiHODE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 12_13-DiHOME | 1.1119 | 0.7938 | 0.4593 | 1.7454 | 0.7008 | 1.1778 | 1.4009 | 1.2000 | 1.0449 |
| 12(13)-Ep-9-KODE | 1.3509 | 1.0573 | 1.1350 | 1.3661 | 0.6679 | 1.2652 | 0.7627 | 0.3975 | 0.4540 |
| 12(13)-EpODE | 1.1190 | 0.9888 | 0.6134 | 1.9331 | 0.7063 | 0.8699 | 1.3532 | 0.9219 | 0.7732 |
| 12(13)-EpOME | 1.0058 | 0.8696 | 0.7052 | 1.3778 | 0.9722 | 1.2218 | 1.0889 | 1.1034 | 1.0748 |
| 12-HEPE | 1.7552 | 0.8453 | 0.6400 | 1.8514 | 0.2370 | 0.3985 | 2.5451 | 0.2944 | 0.1925 |
| 12-HETE | 1.4131 | 1.0144 | 1.0997 | 1.8555 | 0.1522 | 0.5440 | 1.7968 | 0.2849 | 0.3122 |
| 13-HODE | 1.2177 | 1.0618 | 0.9192 | 1.7334 | 0.3300 | 0.8144 | 1.6304 | 0.5137 | 0.5807 |
| 13-HOTE | 1.1536 | 1.5430 | 0.9101 | 1.8066 | 0.2553 | 0.5060 | 1.5818 | 0.3512 | 0.2855 |
| 13-KODE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 14_15-DiHETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 14_15-DiHETrE | 1.1413 | 0.9930 | 0.7560 | 1.2800 | 1.0027 | 0.9189 | 1.1510 | 1.0317 | 0.8350 |
| 14(15)-EpETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 14(15)-EpETrE | 1.0366 | 1.9606 | 0.6359 | 0.8147 | 0.3842 | 1.2850 | 0.3179 | 0.7087 | 0.9803 |
| 14-HDoHE | 1.1022 | 1.3143 | 1.6052 | 1.7737 | 0.1188 | 0.3798 | 1.5081 | 0.1097 | 0.0665 |
| 15_16-DiHODE | 1.2983 | 0.8178 | 0.5243 | 1.2381 | 0.6632 | 0.7179 | 1.9918 | 1.1732 | 0.9349 |
| 15(16)-EpODE | 1.1416 | 0.7455 | 0.5303 | 1.8162 | 0.7595 | 0.9598 | 1.4721 | 1.3194 | 0.8382 |
| 15-deoxy PGJ2 | 1.1727 | 1.4682 | 0.8136 | 0.5727 | 0.8636 | 0.9545 | 0.9636 | 0.6455 | 1.2364 |
| 15-HEPE | 0.9005 | 1.5684 | 1.2037 | 2.2474 | 0.1302 | 0.4428 | 1.3023 | 0.3237 | 0.2084 |
| 15-HETE | 1.1930 | 1.4696 | 1.2836 | 1.5122 | 0.2462 | 0.5505 | 1.0915 | 0.4545 | 0.2529 |
| 15-KETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 15-Keto PGE2 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 16(17)-EpDPE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 17_18-DiHETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 17(18)-EpETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 17-HDoHE | 0.4023 | 1.6780 | 2.0389 | 1.5955 | 0.0488 | 0.3235 | 0.7333 | 0.1354 | 0.0677 |
| 19_20-DiHDoPA | 1.0795 | 0.9430 | 0.7195 | 1.3250 | 0.9755 | 1.1251 | 1.1202 | 1.0754 | 0.8945 |
| 19(20)-EpDPE | 1.4962 | 0.6889 | 0.6722 | 2.4034 | 0.7674 | 0.6960 | 1.1184 | 0.3926 | 0.4759 |
| 20-HETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 4-HDoHE | 0.9708 | 1.0234 | 0.9508 | 1.7540 | 0.9858 | 1.0784 | 0.7206 | 1.0259 | 0.5455 |
| 5_15-DiHETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 5_6-DiHETrE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 5-HEPE | 1.4370 | 1.0780 | 0.5650 | 1.7236 | 0.7262 | 0.7608 | 1.0321 | 1.0301 | 0.5671 |
| 5-HETE | 1.3469 | 1.0130 | 0.6090 | 1.1846 | 0.8875 | 1.0267 | 0.7247 | 1.5082 | 0.7306 |
| 5-KETE | 0.7500 | 1.0517 | 0.5948 | 0.7931 | 0.5345 | 1.5345 | 0.4397 | 2.2241 | 1.3276 |
| 6-keto PGF1a | 1.0354 | 1.0177 | 1.3938 | 1.3274 | 0.7522 | 0.8407 | 0.9735 | 0.5310 | 0.4646 |
| 6-trans-LTB4 | 0.1871 | 0.9513 | 1.7232 | 2.4620 | NA | 0.2105 | 0.0702 | NA | NA |
| 8_15-DiHETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 8_9-DiHETrE | 1.0641 | 1.2179 | 0.6744 | 1.6000 | 0.9077 | 0.9026 | 0.8154 | 1.0821 | 0.7795 |
| 8(9)-EpETrE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 8-HETE | 1.0283 | 1.3955 | 0.9960 | 1.2413 | 0.3232 | 1.0356 | 1.1458 | 0.6721 | 0.6317 |
| 9_10-DiHODE | 1.3154 | 0.6981 | 0.3916 | 1.5665 | 0.6726 | 0.8939 | 1.7879 | 1.2558 | 1.0131 |
| 9_10-DiHOME | 1.0353 | 0.7214 | 0.4852 | 1.2127 | 0.7159 | 1.9406 | 1.1161 | 1.0303 | 1.5007 |
| 9_10-e-DiHO | 0.9737 | 1.5305 | 0.6890 | 1.3626 | 0.7880 | 0.8931 | 0.9533 | 0.7737 | 0.8431 |
| 9_10-EpO | 0.5537 | 2.2348 | NA | 0.1466 | 0.4297 | 0.1161 | NA | 0.1306 | NA |
| 9(10)-EpODE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 9(10)-EpOME | 0.9613 | 0.8557 | 0.8717 | 1.3512 | 0.8975 | 1.4254 | 0.8961 | 0.8634 | 1.1888 |
| 9-HEPE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 9-HETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 9-HODE | 1.2078 | 0.7172 | 0.5906 | 1.4407 | 0.6904 | 1.2531 | 1.4484 | 1.0464 | 1.0898 |
| 9-HOTE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 9-KODE | 1.1139 | 1.0024 | 1.2832 | 1.4938 | 0.3806 | 1.1830 | 0.8602 | 0.5203 | 0.7633 |
| Lipoxin A4 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| LTB4 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| LTB5 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| PGD2 | 1.1343 | 1.2008 | 0.8175 | 1.8227 | 0.8918 | 0.6884 | 1.3455 | 0.4615 | 0.4850 |
| PGE2 | 1.9340 | 1.0444 | 0.9361 | 1.0830 | 0.3017 | 0.4487 | 1.2610 | 0.5725 | 0.2785 |
| PGF2a | 1.8017 | 1.0601 | 0.9050 | 1.2235 | 0.4441 | 0.5321 | 1.2486 | 0.4190 | 0.5992 |
| Resolvin D1 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| SUM-TriHOME | 0.9669 | 1.4814 | 1.2966 | 1.4699 | 0.4382 | 0.6337 | 0.8313 | 0.6143 | 0.5227 |
| TXB2 | 1.3291 | 0.7911 | 1.2683 | 1.1654 | 0.2612 | 0.6878 | 1.5332 | 0.6870 | 0.3588 |
Factors:
| F1 | Treatment:Control | Day:Day 0 |
| F2 | Treatment:Control | Day:Day 12 |
| F3 | Treatment:Control | Day:Day 8 |
| F4 | Treatment:Pravastatin | Day:Day 0 |
| F5 | Treatment:Pravastatin | Day:Day 12 |
| F6 | Treatment:Pravastatin | Day:Day 8 |
| F7 | Treatment:Simvastatin | Day:Day 0 |
| F8 | Treatment:Simvastatin | Day:Day 12 |
| F9 | Treatment:Simvastatin | Day:Day 8 |
