Data for (Study ST001213)
(Analysis AN002024)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 10-HDHA | 1.0497 | 0.7902 | 0.8887 | 1.2714 |
| 11,12-diHETrE | 0.9110 | 0.7634 | 0.7939 | 1.5317 |
| 11(12)-EET | 0.4911 | 0.9095 | 0.8627 | 1.6138 |
| 11-beta-PGF2a/PGF2b | 0.5310 | 0.4320 | 0.9825 | 2.0545 |
| 11-dehydro TxB2 | 1.0570 | 0.7570 | 1.0856 | 1.0003 |
| 11-HDHA | 1.0644 | 0.9160 | 0.7107 | 1.3089 |
| 11-HEPE | 0.8103 | 0.8327 | 0.7381 | 1.6188 |
| 11-HETE | 0.6875 | 0.6873 | 0.9246 | 1.7006 |
| 12,13-diHOME | 0.7585 | 0.6883 | 0.8671 | 1.6861 |
| 12(13)-EpOME | 0.8906 | 0.9893 | 0.8442 | 1.2759 |
| 12-HEPE | 0.9579 | 0.7203 | 0.8660 | 1.4557 |
| 12-HETE | 0.8572 | 0.7021 | 0.8298 | 1.6109 |
| 12-oxoETE | 0.7730 | 1.0968 | 0.5103 | 1.5551 |
| 12-oxoLTB4 | 0.6490 | 1.6624 | 0.4646 | 1.4521 |
| 13,14-dihydro-15-keto PGA2 | 1.1416 | 0.8072 | 0.8934 | 1.1578 |
| 13,14-dihydro-15-keto PGD2 | 0.9409 | 0.6733 | 0.7597 | 1.6261 |
| 13,14-dihydro-15-keto PGE2 | 0.7727 | 1.1114 | 0.7187 | 1.3972 |
| 13,14-dihydro-15-keto PGF2a | 0.4487 | 1.1005 | 0.8141 | 1.7641 |
| 13,14-dihydro PGE1 | 0.8244 | 0.9605 | 1.9647 | 0.3222 |
| 13-HDHA | 0.8338 | 0.9456 | 0.8063 | 1.4143 |
| 13-HODE | 0.7238 | 1.0344 | 0.8767 | 1.3651 |
| 13-HOTrE/13-HOTrE(r) | 0.1558 | 2.6876 | 0.2276 | 0.9290 |
| 13-oxoODE | 0.0748 | 3.1407 | 0.0935 | 0.6910 |
| 14,15-diHETE | 0.8444 | 1.6019 | 0.5462 | 1.0386 |
| 14,15-diHETrE | 0.9203 | 0.8840 | 0.9429 | 1.2528 |
| 14(15)-EET | 0.6926 | 0.8063 | 1.0688 | 1.4323 |
| 14(15)-EpETE | 0.3986 | 0.9194 | 0.8667 | 1.8152 |
| 14-HDHA | 1.0226 | 0.8281 | 0.8647 | 1.2846 |
| 15-deoxy-delta12,14-PGD2 | 0.5324 | 1.4009 | 0.4722 | 1.6813 |
| 15-deoxy-delta12,14-PGJ2 | 1.2351 | 0.7431 | 1.0168 | 1.0013 |
| 15-HEPE | 1.1973 | 0.8254 | 0.8886 | 1.0887 |
| 15-HETE | 0.6756 | 0.6844 | 0.8679 | 1.7720 |
| 15-HETrE | 0.9208 | 0.9773 | 0.8617 | 1.2402 |
| 15-keto-PGE2 | NA | NA | NA | NA |
| 15-keto-PGF2a | 0.3137 | 0.6702 | 0.4696 | 2.3692 |
| 15-oxoETE | 0.1081 | 2.6469 | 0.1937 | 1.0513 |
| 16(17)-EpDPE | 0.7696 | 0.8031 | 0.9704 | 1.4568 |
| 16-HDHA | 0.8233 | 0.9251 | 0.8510 | 1.4006 |
| 16-HETE | 0.9153 | 0.7700 | 1.1785 | 1.2142 |
| 17,18-diHETE | 0.8010 | 1.0050 | 0.7501 | 1.4440 |
| 17(18)-EpETE | 0.9341 | 1.1953 | 1.0430 | 0.7932 |
| 17-HDHA | 0.9950 | 0.7270 | 1.8370 | 0.7185 |
| 17-HETE | 0.5127 | 0.8161 | 1.0558 | 1.6154 |
| 18-HEPE | 0.8179 | 1.2256 | 0.6895 | 1.2671 |
| 18-HETE | 0.7266 | 0.8168 | 0.8783 | 1.5783 |
| 19,20-diHDPA | 1.2790 | 1.0291 | 0.4123 | 1.2795 |
| 19(20)-EpDPE | 0.6529 | 1.1848 | 0.9167 | 1.2456 |
| 19/20-OH PGE2 | NA | NA | NA | 1.0000 |
| 19/20-OH PGF2a | 1.3684 | 1.1386 | 0.6025 | 0.8184 |
| 20-carboxy LTB4 | 0.8369 | 0.8644 | 1.4099 | 1.1197 |
| 20-HDHA | 0.7176 | 1.2359 | 0.6272 | 1.4194 |
| 20-HETE | 0.7351 | 0.7234 | 0.6276 | 1.6873 |
| 2,3-dinor-11beta-PGF2a | 1.0000 | NA | NA | NA |
| 2,3-dinor TxB2 | 0.9812 | 0.5861 | 0.8667 | 1.2838 |
| 4-HDHA | 0.5623 | 1.5765 | 0.5990 | 1.2622 |
| 5,15-diHETE | 1.0986 | 1.0065 | 0.3033 | 1.4931 |
| 5,6-diHETE | 0.4730 | 0.8759 | 0.9879 | 1.5300 |
| 5,6-diHETrE | 0.9446 | 0.9436 | 0.9419 | 1.1700 |
| 5(6)-EET | 0.7576 | 0.9219 | 0.6836 | 1.4446 |
| 5-HEPE | 0.9080 | 0.9348 | 0.7870 | 1.3702 |
| 5-HETE | 0.6825 | 1.1628 | 0.7534 | 1.4012 |
| 5-HETrE | 0.8944 | 0.4459 | 1.1190 | 1.5232 |
| 5-iPF2a-VI | 0.8851 | 1.2365 | 0.7272 | 1.1512 |
| 5-oxoETE | 0.2133 | 2.3671 | 0.3024 | 0.9860 |
| 6,15-diketo-13,14-dihydro PGF1a | 1.1909 | 1.2399 | 0.5929 | 0.7605 |
| 6-keto PGE1 | 0.7801 | 1.9032 | 0.8952 | 0.9346 |
| 6-keto-PGF1a | 0.5035 | 0.5950 | 1.1499 | 1.7515 |
| 7-HDHA | 0.6250 | 1.3149 | 0.7696 | 1.2906 |
| 8,9-diHETrE | 0.6552 | 1.0886 | 0.9585 | 1.2976 |
| 8(9)-EET | NA | 1.2672 | 1.0202 | 0.6924 |
| 8-HDHA | 0.8902 | 0.8741 | 0.8283 | 1.4074 |
| 8-HEPE | 0.9444 | 0.6844 | 0.8925 | 1.4788 |
| 8-HETE | 0.8946 | 0.7750 | 0.7858 | 1.5446 |
| 8-HETrE | 1.3749 | 0.7146 | 0.6476 | 1.2629 |
| 8-iso PGF2a | 0.6019 | 0.2883 | 0.7311 | 2.3787 |
| 9,10-diHOME | 0.7803 | 0.7075 | 0.9165 | 1.5956 |
| 9(10)-EpOME | 1.0000 | NA | NA | NA |
| 9-HEPE | 1.0160 | 0.7086 | 0.8139 | 1.4615 |
| 9-HETE | 0.8444 | 0.7154 | 0.8395 | 1.6008 |
| 9-HODE | 0.7265 | 1.0523 | 0.7312 | 1.4899 |
| 9-HOTrE | 0.7245 | 1.4757 | 0.7953 | 1.0045 |
| 9-oxoODE | 0.0486 | 2.0496 | 0.1789 | 1.7882 |
| Bicyclo PGE2 | 1.1884 | 0.7527 | 0.5102 | 1.3344 |
| d4-9-HODE | NA | NA | NA | NA |
| d4-LTB4 | NA | NA | NA | NA |
| d4-PGE2 | NA | NA | NA | NA |
| d8-5S-HETE | NA | NA | NA | NA |
| delta12-PGJ2 | 0.4335 | 0.8382 | 0.8781 | 1.7084 |
| Hepoxilin A3 | 0.6544 | 1.3757 | 0.7642 | 1.2057 |
| LTB4 | 0.6338 | 0.9269 | 0.8355 | 1.6038 |
| LTC4 | NA | NA | 1.4689 | 0.7655 |
| LTD4 | 1.1952 | 0.6624 | 1.3269 | 0.7232 |
| LTE4 | NA | NA | NA | 1.0000 |
| LXA4 | 0.7941 | 1.0778 | 0.5746 | 1.4684 |
| LXB4 | 0.7848 | 1.3853 | 0.5910 | 0.8870 |
| Maresin1 | 1.4072 | 0.7685 | 0.6880 | 1.0968 |
| PD1 | 0.9588 | 1.0642 | 0.6896 | 1.2874 |
| PGA1 | 1.0227 | 0.5791 | 1.7183 | 0.6962 |
| PGA2/PGJ2 | 0.4800 | 0.8567 | 1.1237 | 1.5396 |
| PGB2 | 0.3288 | 0.9351 | 0.5787 | 2.0058 |
| PGD2 | 0.6922 | 0.3294 | 0.7717 | 2.3407 |
| PGD3/PGE3 | 0.5632 | 1.1134 | 1.0925 | 0.9316 |
| PGE1/PGD1 | 0.6843 | 0.6750 | 0.8425 | 2.1972 |
| PGE2/PGD2 | 0.6701 | 0.9165 | 0.7824 | 1.5760 |
| PGF1a | 1.1384 | 0.9487 | 1.0143 | 0.8986 |
| PGF2a | 0.4606 | 0.4957 | 0.8974 | 2.1464 |
| PGK2 | 1.1172 | 0.4634 | 1.2583 | 1.0146 |
| RvD1 | 0.4977 | 2.3821 | 0.3539 | 1.2270 |
| RvD2 | 1.3186 | 1.6491 | 0.4334 | 0.4690 |
| Tetranor-12-HETE | 0.8548 | 0.6713 | 0.7269 | 1.7469 |
| tetranor-PGFM | NA | NA | 0.8400 | 1.3200 |
| TxB2 | 0.5528 | 0.6535 | 0.9502 | 1.8435 |
| TxB3 | 1.0707 | 0.5459 | 0.7927 | 1.7043 |
Factors:
| F1 | Temperature:22C | Genotype:KO |
| F2 | Temperature:22C | Genotype:WT |
| F3 | Temperature:5C | Genotype:KO |
| F4 | Temperature:5C | Genotype:WT |
