Data for (Study ST001235)
(Analysis AN002053)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 |
---|---|---|---|---|---|---|
1-methylhistamine | 0.9985 | 1.0037 | 0.9985 | 0.9963 | 1.0002 | 1.0034 |
2-deoxycytidine | 0.9331 | 1.0369 | 0.9955 | 0.9858 | 1.0156 | 1.0566 |
3-hydroxyanthranilic acid | 0.9925 | 0.9946 | 0.9935 | 1.0015 | 1.0023 | 1.0187 |
3-nitro-L-tyrosine | 0.9985 | 1.0022 | 0.9915 | 1.0100 | 0.9919 | 1.0072 |
5-aminolevulinic acid | 0.9989 | 0.9962 | 0.9996 | 0.9992 | 1.0010 | 1.0056 |
5-HIAA | 0.9934 | 0.9952 | 1.0103 | 1.0016 | 0.9985 | 1.0022 |
5-methylthioadenosine | 1.0102 | 0.9883 | 0.9935 | 1.0090 | 1.0117 | 0.9845 |
adenine | 0.9972 | 0.9967 | 0.9983 | 1.0048 | 1.0126 | 0.9915 |
adenosine | 0.9955 | 1.0219 | 0.9942 | 1.0001 | 0.9871 | 1.0033 |
ADMA | 0.9990 | 0.9970 | 1.0021 | 1.0010 | 1.0004 | 1.0005 |
alanine | 0.9986 | 0.9987 | 0.9986 | 1.0026 | 0.9982 | 1.0038 |
alpha-glycerophosphocholine | 0.9976 | 1.0065 | 0.9981 | 1.0052 | 0.9954 | 0.9983 |
aminoisobutyric acid | 0.9964 | 0.9881 | 1.0117 | 0.9988 | 1.0025 | 1.0027 |
anserine | 1.0426 | 1.0172 | 0.9454 | 0.9755 | 0.9909 | 1.0179 |
arginine | 1.0001 | 1.0005 | 0.9983 | 0.9991 | 1.0015 | 1.0005 |
argininosuccinate | 1.0121 | 0.9881 | 0.9975 | 0.9952 | 1.0096 | 0.9936 |
asparagine | 0.9961 | 0.9982 | 0.9972 | 1.0067 | 0.9999 | 1.0036 |
aspartate | 1.0055 | 0.9914 | 1.0018 | 1.0016 | 1.0097 | 0.9880 |
beta-alanine | 1.0075 | 0.9972 | 0.9889 | 1.0053 | 1.0074 | 0.9921 |
betaine | 0.9988 | 1.0007 | 0.9990 | 1.0019 | 0.9989 | 1.0012 |
butyrobetaine | 0.9980 | 0.9952 | 1.0049 | 1.0003 | 1.0032 | 0.9986 |
C10:2 carnitine | 1.0096 | 1.0070 | 1.0140 | 0.9758 | 1.0032 | 0.9859 |
C10 carnitine | 1.0089 | 1.0031 | 1.0170 | 0.9834 | 1.0024 | 0.9806 |
C12:1 carnitine | 1.0088 | 1.0037 | 1.0168 | 0.9841 | 1.0076 | 0.9745 |
C12 carnitine | 1.0055 | 1.0012 | 1.0177 | 0.9859 | 1.0060 | 0.9802 |
C14:1 carnitine | 1.0063 | 1.0042 | 1.0193 | 0.9838 | 1.0094 | 0.9732 |
C14:2 carnitine | 1.0077 | 1.0061 | 1.0157 | 0.9865 | 1.0053 | 0.9747 |
C14 carnitine | 1.0001 | 0.9977 | 1.0159 | 0.9926 | 1.0080 | 0.9842 |
C16 carnitine | 0.9923 | 1.0027 | 1.0079 | 1.0022 | 1.0037 | 0.9930 |
C16-OH carnitine | 0.9993 | 0.9997 | 1.0119 | 0.9946 | 1.0062 | 0.9875 |
C18:1 carnitine | 0.9949 | 1.0008 | 1.0134 | 0.9940 | 1.0088 | 0.9886 |
C18:1-OH carnitine | 1.0057 | 1.0100 | 1.0167 | 0.9807 | 1.0098 | 0.9736 |
C18:2 carnitine | 0.9894 | 1.0067 | 1.0061 | 1.0039 | 1.0017 | 0.9951 |
C18 carnitine | 0.9943 | 0.9918 | 1.0103 | 0.9996 | 1.0111 | 0.9939 |
C20:4 carnitine | 0.9841 | 1.0046 | 1.0068 | 1.0111 | 1.0032 | 0.9949 |
C20 carnitine | 0.9952 | 0.9966 | 1.0038 | 1.0006 | 1.0076 | 0.9976 |
C22:6 carnitine | 0.9985 | 1.0044 | 1.0232 | 0.9958 | 1.0130 | 0.9633 |
C26 carnitine | 0.9961 | 0.9982 | 0.9987 | 0.9991 | 1.0034 | 1.0060 |
C2 carnitine | 1.0001 | 1.0005 | 1.0012 | 0.9984 | 1.0016 | 0.9980 |
C3 carnitine | 0.9991 | 0.9921 | 0.9986 | 1.0031 | 1.0023 | 1.0052 |
C4 carnitine | 0.9970 | 0.9943 | 0.9999 | 1.0046 | 1.0009 | 1.0044 |
C4-OH carnitine | 1.0009 | 1.0043 | 1.0108 | 0.9905 | 1.0071 | 0.9851 |
C5:1 carnitine | 0.9967 | 0.9929 | 1.0051 | 1.0005 | 1.0016 | 1.0039 |
C5 carnitine | 1.0011 | 0.9867 | 1.0000 | 0.9999 | 1.0054 | 1.0065 |
C5-DC carnitine | 1.0010 | 0.9991 | 1.0050 | 0.9939 | 1.0011 | 0.9992 |
C6 carnitine | 1.0072 | 1.0032 | 1.0109 | 0.9851 | 1.0058 | 0.9843 |
C7 carnitine | 1.0088 | 0.9918 | 1.0079 | 0.9956 | 1.0041 | 0.9883 |
C9 carnitine | 1.0084 | 0.9977 | 1.0047 | 0.9940 | 0.9994 | 0.9926 |
cAMP | 0.9757 | 1.0004 | 1.0262 | 0.9853 | 0.9829 | 1.0322 |
carnitine | 0.9999 | 0.9988 | 0.9999 | 1.0003 | 1.0010 | 1.0002 |
choline | 0.9996 | 0.9970 | 1.0000 | 1.0032 | 0.9999 | 1.0005 |
citrulline | 1.0005 | 1.0009 | 0.9963 | 1.0006 | 0.9980 | 1.0038 |
cotinine | 1.0028 | 1.0010 | 0.9799 | 1.0141 | 0.9969 | 1.0061 |
creatine | 1.0016 | 0.9962 | 0.9985 | 0.9979 | 1.0042 | 1.0012 |
creatinine | 1.0025 | 0.9972 | 1.0045 | 0.9931 | 1.0041 | 0.9974 |
cytosine | 0.9967 | 0.9821 | 0.9863 | 1.0187 | 1.0024 | 1.0161 |
dimethylglycine | 1.0000 | 0.9926 | 1.0049 | 0.9997 | 1.0011 | 1.0013 |
epinephrine | 1.0044 | 1.0026 | 0.9992 | 0.9952 | 0.9971 | 1.0000 |
GABA | 1.0023 | 0.9966 | 1.0013 | 0.9963 | 0.9949 | 1.0078 |
glutamate | 1.0123 | 0.9827 | 1.0028 | 0.9999 | 1.0117 | 0.9862 |
glutamine | 1.0017 | 1.0056 | 0.9922 | 1.0006 | 0.9953 | 1.0047 |
glycine | 0.9999 | 1.0009 | 0.9996 | 0.9994 | 1.0011 | 0.9993 |
guanidinoacetic acid | 0.9927 | 1.0081 | 0.9927 | 1.0016 | 0.9943 | 1.0136 |
guanine | 1.0000 | 0.9985 | 1.0040 | 0.9994 | 0.9991 | 0.9987 |
histamine | 0.9958 | 1.0038 | 0.9971 | 1.0016 | 0.9975 | 1.0058 |
histidine | 1.0000 | 1.0017 | 0.9969 | 1.0005 | 0.9992 | 1.0021 |
homocysteine | 0.9955 | 0.9959 | 0.9929 | 1.0108 | 0.9949 | 1.0121 |
hydroxyproline | 0.9981 | 0.9920 | 1.0147 | 1.0261 | 0.9879 | 0.9805 |
hypoxanthine | 1.0057 | 0.9964 | 0.9955 | 0.9994 | 0.9983 | 1.0033 |
isoleucine | 1.0000 | 0.9960 | 0.9977 | 1.0052 | 0.9986 | 1.0027 |
Kyn/Trp (log10) | NA | NA | NA | NA | NA | NA |
kynurenic acid | 1.0015 | 0.9964 | 1.0071 | 0.9952 | 1.0028 | 0.9958 |
kynurenine | 0.9864 | 0.9724 | 1.0223 | 1.0024 | 1.0265 | 0.9925 |
leucine | 1.0003 | 0.9976 | 0.9966 | 1.0054 | 1.0002 | 1.0002 |
lysine | 1.0009 | 0.9996 | 0.9981 | 1.0003 | 1.0015 | 0.9994 |
melatonin | 1.0133 | 0.9982 | 0.9995 | 0.9779 | 1.0148 | 0.9918 |
methionine | 0.9982 | 0.9962 | 0.9972 | 1.0046 | 0.9977 | 1.0069 |
methionine sulfoxide | 1.0011 | 0.9812 | 1.0031 | 1.0071 | 1.0033 | 1.0036 |
mevalonic acid | 1.0035 | 0.9928 | 1.0045 | 1.0110 | 0.9984 | 0.9882 |
N-carbamoyl-beta-alanine | 0.9954 | 0.9816 | 1.0103 | 1.0040 | 1.0069 | 1.0024 |
niacinamide | 0.9889 | 1.0049 | 0.9939 | 0.9935 | 1.0123 | 1.0107 |
NMMA | 0.9987 | 0.9994 | 0.9983 | 1.0008 | 0.9992 | 1.0043 |
ornithine | 0.9991 | 1.0058 | 0.9973 | 0.9993 | 0.9961 | 1.0029 |
phenylalanine | 0.9988 | 0.9937 | 1.0022 | 1.0042 | 1.0048 | 0.9964 |
pipecolic acid | 1.0007 | 1.0035 | 0.9985 | 0.9989 | 0.9949 | 1.0034 |
proline | 0.9981 | 0.9994 | 0.9980 | 1.0026 | 0.9993 | 1.0033 |
putrescine | 1.0155 | 0.9964 | 1.0131 | 0.9742 | 0.9942 | 1.0008 |
pyroglutamic acid | 1.0007 | 1.0035 | 0.9985 | 0.9989 | 0.9949 | 1.0034 |
quinolinic acid | 0.9612 | 0.9653 | 1.0108 | 1.0266 | 1.0034 | 1.0453 |
S-adenosylhomocysteine | 0.9822 | 0.9924 | 0.9961 | 1.0056 | 1.0203 | 1.0097 |
sarcosine | 0.9936 | 0.9856 | 1.0090 | 0.9960 | 1.0096 | 1.0072 |
SDMA | 1.0004 | 0.9967 | 1.0048 | 0.9973 | 1.0013 | 0.9991 |
serine | 0.9999 | 0.9986 | 0.9985 | 1.0023 | 1.0003 | 1.0006 |
serotonin | 1.0044 | 1.0091 | 0.9918 | 0.9967 | 0.9935 | 1.0037 |
spermine | 1.0001 | 0.9827 | 1.0065 | 1.0084 | 0.9965 | 1.0050 |
taurine | 0.9978 | 1.0041 | 1.0030 | 0.9975 | 0.9986 | 0.9994 |
thiamine | 0.9949 | 0.9906 | 0.9894 | 1.0170 | 0.9954 | 1.0153 |
threonine | 1.0007 | 0.9987 | 0.9977 | 0.9979 | 0.9982 | 1.0067 |
thymidine | 1.0141 | 0.9968 | 1.0106 | 1.0042 | 0.9668 | 1.0018 |
thyroxine | 1.0007 | 0.9970 | 1.0084 | 1.0036 | 1.0031 | 0.9863 |
triiodothyronine | 0.9938 | 0.9960 | 1.0098 | 1.0094 | 1.0049 | 0.9871 |
trimethylamine-N-oxide | 0.9961 | 0.9956 | 1.0063 | 0.9953 | 1.0046 | 1.0029 |
tryptophan | 1.0013 | 0.9949 | 0.9996 | 1.0040 | 0.9996 | 1.0001 |
tyrosine | 0.9992 | 0.9961 | 0.9993 | 1.0025 | 1.0017 | 1.0017 |
uracil | 1.0027 | 1.0036 | 0.9777 | 1.0051 | 1.0075 | 1.0044 |
valine | 1.0001 | 0.9978 | 0.9962 | 1.0051 | 1.0006 | 1.0005 |
xanthosine | 1.0269 | 0.9815 | 1.0058 | 0.9951 | 0.9959 | 0.9852 |
Factors:
F1 | Time point:baseline | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- |
F2 | Time point:baseline | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 |
F3 | Time point:week 4 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- |
F4 | Time point:week 4 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 |
F5 | Time point:week 6 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):- |
F6 | Time point:week 6 | OS_Censor (1 means the time is a censoring time and 0 means a failure time in OS):1 |