Data for (Study ST001280)

(Analysis AN002121)

Values for each metabolite have been scaled by dividing by the mean across all factors

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Metabolite	F1	F2	F3	F4	F5	F6	F7	F8
1-Methylnicotinamide	0.9240	0.9780	1.0855	0.8898	0.9105	0.9610	1.0246	1.2267
2-Oxoglutarate	0.7004	1.3438	0.9664	0.8766	0.6074	1.0285	1.0310	1.4459
2-Oxoisocaproate	0.8981	1.4218	0.9750	0.6688	0.8798	1.0308	1.0426	1.0832
3-Indoxylsulfate	0.8887	1.1058	0.6205	0.8191	0.8234	1.1555	1.0742	1.5128
Acetate	0.8929	0.9274	0.5201	0.7921	1.1436	1.6957	0.9928	1.0355
Allantoin	0.8937	1.0589	1.0296	1.0271	0.9899	0.9517	0.9118	1.1373
Ascorbate	0.8862	1.8991	0.7460	0.1928	0.8876	0.9883	1.0856	1.3143
Betaine	0.8731	1.4079	1.1051	1.0013	0.6111	1.2579	1.0279	0.7156
Carnitine	1.2163	0.7529	0.7055	0.7048	1.1868	1.2599	1.0039	1.1699
Choline	0.1037	4.5763	1.8719	1.0263	0.0904	0.1173	0.1082	0.1060
cis-Aconitate	0.7615	1.1260	1.1149	0.8390	0.8831	0.9992	0.9999	1.2765
Citrate	0.7911	0.9195	1.1630	0.9033	0.9850	0.9665	0.9900	1.2816
Creatine	0.7192	1.2035	1.1092	0.7859	0.8901	1.3268	0.8831	1.0821
Creatinine	0.7797	1.1261	1.0807	0.8902	0.7623	0.9838	1.0727	1.3043
Dimethylamine	0.6666	1.4240	1.0660	1.0906	0.6507	0.9414	0.9632	1.1974
Formate	0.9796	1.2170	0.8328	1.1274	1.1574	1.1184	0.7464	0.8669
Glycine	0.7828	1.3313	0.8753	0.6778	0.8203	1.0057	1.2026	1.3043
Glycolate	0.7620	0.8632	0.8371	0.8412	1.2793	0.7995	1.1899	1.4278
Hippurate	0.7338	1.4437	1.4279	1.6915	0.2821	0.3236	0.8706	1.2268
Lactate	0.7906	0.4743	0.5050	0.5069	3.0758	1.7506	0.5248	0.8764
Methionine	0.8784	0.9278	0.6265	0.2468	0.8007	1.4577	1.4556	1.6065
Methylamine	0.5751	1.1031	0.9615	1.0772	0.5746	1.1898	1.1522	1.3667
N-Carbamoyl-β-alanine	0.8282	1.1686	1.4079	1.1037	0.8574	0.7817	0.8548	0.9978
N-Isovaleroylglycine	0.8499	1.1841	0.7295	0.4349	0.8923	1.1152	1.1949	1.5991
N,N-Dimethylglycine	0.9370	1.1757	1.2467	1.1952	0.9737	1.0795	0.7583	0.6339
Phenylalanine	0.8521	1.1116	0.8166	0.8805	0.8775	1.1541	0.9530	1.3546
Succinate	0.8368	1.1028	1.0204	0.8402	0.9180	1.0707	0.9844	1.2268
Taurine	0.9299	1.0565	0.8848	0.4747	1.0583	1.2410	1.0726	1.2822
trans-Aconitate	0.7125	1.2171	0.9983	1.1727	0.7257	1.0699	0.9184	1.1854
Trigonelline	0.8173	1.3598	1.0046	0.8605	0.8347	1.2127	0.9577	0.9527
Trimethylamine	0.4157	1.5362	1.1543	1.1017	0.4386	0.8324	1.1458	1.3754
Trimethylamine N-oxide	0.3846	1.8042	1.3454	1.5140	0.4557	0.5716	0.8579	1.0666
Tyrosine	1.0816	1.3887	0.8196	0.7108	0.9759	0.8781	1.0383	1.1070
Urea	1.1706	0.8820	0.5573	1.0496	1.1601	1.1356	0.8446	1.2001

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Factors:

F1	Condition:CFZ | Timepoint (weeks):-
F2	Condition:CFZ | Timepoint (weeks):2
F3	Condition:CFZ | Timepoint (weeks):4
F4	Condition:CFZ | Timepoint (weeks):8
F5	Condition:Placebo | Timepoint (weeks):-
F6	Condition:placebo | Timepoint (weeks):2
F7	Condition:placebo | Timepoint (weeks):4
F8	Condition:placebo | Timepoint (weeks):8