Data for (Study ST001523)

(Analysis AN002541)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Metabolite	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12
1-monoolein	0.6021	1.0976	1.3005	0.5780	0.6157	1.1435	1.2789	0.6828	1.5059	1.3743	0.8652	1.0261
1-monopalmitin	0.8443	0.6828	0.7988	1.3592	1.2183	0.8601	0.8441	0.9511	1.1569	1.1586	0.7749	1.1766
1-monostearin	0.9954	0.9088	0.8602	1.7956	1.1312	0.6894	0.6990	0.8961	0.9457	1.0581	0.9142	0.9687
2,3-dihydroxybutanoic acid NIST	1.4860	1.0848	0.8130	1.0584	0.9004	0.5680	1.7377	1.2585	0.6310	1.2247	0.8169	0.5564
2,5-dihydroxypyrazine NIST	1.1569	1.2834	1.0188	0.9111	1.0943	1.0628	0.8737	1.0458	0.9129	0.9558	0.9273	0.8421
2-deoxytetronic acid	1.0410	0.9957	0.8659	0.9056	0.9534	0.7674	1.0797	1.1804	0.8341	1.2176	1.1635	0.9781
2-hydroxybutanoic acid	1.5407	0.7315	0.7914	1.1187	0.5037	0.6844	1.5933	1.2035	0.6586	1.8477	0.8031	0.5410
2-hydroxyglutaric acid	1.1978	1.5303	0.8297	0.8013	1.0293	0.8424	0.8557	1.0956	0.8858	0.7450	1.2023	1.1411
2-ketoisocaproic acid	1.1826	1.0045	0.9229	1.2302	0.8734	0.6927	1.2595	1.1335	0.8341	1.2165	0.9806	0.6889
3-hydroxybutyric acid	2.1626	0.7740	0.3283	1.6957	0.6488	0.1960	1.8977	1.0968	0.2941	2.1064	0.6488	0.1456
5-methoxytryptamine	0.9214	0.8049	0.8806	1.0320	0.9607	0.9744	1.0800	1.0127	1.0954	1.1204	1.0347	0.9969
aconitic acid	1.5538	1.4598	1.0275	0.6056	0.7729	0.7817	0.5699	0.9136	1.0415	0.9599	1.3866	1.1430
adenosine	0.4240	0.3049	0.9864	0.5364	1.2256	1.0302	0.5391	0.7334	2.4320	0.9707	1.3071	1.2844
adenosine-5-monophosphate	0.8203	0.7892	1.1249	1.1519	1.3358	1.3240	0.6634	0.5835	1.0479	1.1285	0.9715	0.8629
alanine	0.8618	0.8964	1.1839	0.9111	0.7703	1.2856	0.8891	0.8918	1.1669	0.8902	0.9396	1.3375
allantoic acid	0.8792	0.8709	0.6564	1.1680	1.1249	0.5576	0.6763	1.2890	0.5151	1.2504	1.5444	1.2614
alpha-aminoadipic acid	1.3296	1.1244	0.9403	0.9133	0.8220	0.8944	1.3014	1.0508	1.0596	0.9338	0.8073	0.9937
alpha-ketoglutarate	0.8196	1.5045	0.9002	0.7429	0.9169	0.9980	1.0348	1.2935	1.3263	0.5648	1.0388	1.0202
aminomalonate	1.3282	0.8301	0.9753	0.9752	0.8756	1.3956	0.9718	1.0451	1.0011	0.9059	0.8031	0.9228
arabinose	1.3378	0.6203	1.0253	1.3295	0.8583	1.0074	1.0033	0.7075	0.9827	0.9414	1.0169	1.1413
arabitol	0.8697	1.0214	1.2389	0.6713	0.7984	1.0856	0.7970	0.9646	1.3988	0.8750	0.9305	1.4770
arachidic acid	0.9768	0.8588	0.9335	1.0057	1.2231	0.7481	1.1910	0.9669	0.8311	0.9479	1.1878	1.0719
arachidonic acid	1.1849	0.8685	0.8721	1.1292	1.2113	0.5266	1.3671	1.2930	0.8474	1.0360	1.0766	0.5783
asparagine	0.9649	1.6288	0.9467	0.8034	0.7531	0.8922	0.7307	0.9007	1.0451	0.8896	1.3209	1.2708
aspartic acid	0.8390	0.7789	1.1415	0.9620	1.0320	1.5529	0.7974	0.6834	1.0749	0.8585	0.8920	1.2978
behenic acid	0.8376	0.7753	0.8422	2.2502	0.9725	0.6988	0.9180	1.1754	0.7670	0.8585	0.9156	0.7823
benzoic acid	1.1866	0.8256	1.0041	1.1052	1.0402	0.8597	1.0872	0.8666	0.9419	1.1356	1.0369	0.8834
beta-alanine	1.0819	0.9506	1.1936	0.7670	1.1205	0.9721	0.7763	0.8109	1.0630	0.8617	1.1808	1.2757
capric acid	1.1973	0.8492	0.8451	1.0525	1.1885	0.8054	0.8950	1.2455	0.9825	1.1846	1.0704	0.6157
cholesterol	1.0870	0.8429	0.9737	1.1081	1.0666	0.8654	1.0724	0.9332	0.9972	1.1850	0.9480	0.8755
cis-gondoic acid	1.2062	0.9957	0.7672	1.0442	1.1056	0.5722	1.3352	1.5822	0.9486	0.8114	1.0426	0.6544
citric acid	1.0544	1.2349	0.8114	0.9275	1.0548	0.6870	0.9616	1.2671	0.8876	1.0460	1.2005	0.8981
citrulline	0.9443	1.0519	0.9331	0.8495	0.9587	0.9885	0.7780	1.0731	1.1705	0.9391	0.9200	1.4390
conduritol-beta-expoxide	0.4451	0.8463	1.2591	0.4782	0.8487	1.6686	0.5049	0.7220	1.7408	0.6708	0.9310	1.8768
creatinine	1.4888	1.0805	1.0665	1.3877	0.7223	0.8755	1.1697	0.9968	0.6878	1.3686	0.6971	0.5563
cysteine	0.9794	1.2274	1.2145	0.7217	0.9201	1.2269	0.8065	0.7872	1.0129	0.9644	1.1352	1.0794
cystine	1.3093	1.0473	0.8324	1.0642	0.8273	0.9463	1.0824	0.9604	0.9363	1.2872	0.8713	0.8677
dehydroascorbic acid	1.0559	0.9060	0.9673	1.2561	0.9446	1.0316	1.3403	0.8962	0.8307	1.1841	0.7741	0.7696
ethanolamine	1.3298	0.8970	1.0842	0.9987	0.9193	0.7402	1.0137	1.0186	0.9030	1.0480	1.0862	1.0479
fructose	0.8279	0.8718	1.0470	0.8685	1.1883	1.6159	0.7249	0.9235	0.8461	0.8763	1.0612	1.0049
fucose	1.1598	0.9950	0.8283	1.1694	1.0010	0.6189	1.1688	1.1160	0.7254	1.3386	1.1335	0.6990
fumaric acid	1.1335	1.2729	1.0351	1.0836	1.0520	0.8430	0.9676	1.2517	0.9634	0.8489	0.8992	0.7683
galacturonic acid	1.1809	1.1645	0.8904	0.9512	1.0456	0.8166	1.0117	1.1737	0.7428	1.1479	1.0271	0.8889
gluconic acid	0.4739	0.8316	1.6814	0.4009	0.7617	1.7234	0.5646	0.6615	1.4874	0.5894	0.8009	2.1417
glucose	0.8931	1.1391	0.8284	0.9837	1.1135	0.7242	1.3430	1.3033	1.0013	0.8764	1.0859	0.7210
glucose-6-phosphate major	1.8112	0.7172	0.7071	1.3455	1.5489	0.7071	0.6748	0.9179	0.7207	0.9062	1.1621	0.7090
glutamate minor	1.1169	0.9282	1.1672	0.9352	0.7789	1.2484	0.8212	0.8644	1.0794	1.0125	0.9525	1.1427
glutamic acid	0.9844	0.9727	0.9988	0.9854	0.9475	1.2058	0.8418	0.9076	1.0844	0.8992	0.9999	1.1588
glutamine	1.1386	1.0758	0.8877	0.8888	0.9994	0.6691	1.1182	1.1945	0.9880	0.8868	1.1843	1.0478
glyceric acid	1.4317	0.9258	0.7376	1.0690	1.0923	0.6852	1.1135	1.0032	0.9251	1.1939	0.9735	0.8627
glycerol	1.2510	1.1419	0.7960	0.9415	1.0708	0.5371	1.3583	1.2836	0.8745	1.0306	1.1344	0.6594
glycerol-3-galactoside	0.2869	0.9324	1.4587	0.2276	0.6605	1.8724	0.1748	0.7084	2.0109	0.6375	0.9250	2.1640
glycerol-alpha-phosphate	1.1549	0.9837	1.0348	1.0669	1.1544	0.9245	0.9907	1.0483	0.9820	0.9626	0.8429	0.8913
glycine	1.0317	0.8512	1.1046	1.0267	0.9475	1.1278	1.0116	0.8057	0.9990	0.9645	1.0400	1.0699
glycolic acid	0.9364	1.0225	0.8630	1.1518	1.0223	0.9962	0.9003	0.9161	1.0227	1.2735	0.9801	0.8148
heptadecanoic acid	1.0544	0.8741	0.8972	1.0182	1.0622	0.7168	1.2170	1.1550	0.8802	1.0362	1.0917	0.9803
hexadecane	0.8193	1.2302	1.1427	1.4794	1.0684	0.6699	1.2171	0.7932	0.6727	1.0614	1.2003	0.5975
hexitol	1.1388	1.0477	0.9501	0.9629	1.0156	1.0249	1.1456	0.8356	1.1647	0.8167	0.9047	1.0614
hexuronic acid	1.2503	1.1889	0.8045	0.9845	1.0058	0.7278	1.2294	1.0912	0.7869	1.0473	1.1149	0.8291
hippuric acid	0.6049	1.3422	1.0408	0.4845	0.9473	1.3179	0.3874	0.6767	1.6421	0.3777	1.4570	1.7887
histidine	0.8935	1.0077	1.0835	0.7947	0.7557	1.3404	0.8818	1.0268	1.3591	0.7754	0.8574	1.3008
hydrocinnamic acid	0.3096	0.6912	1.1165	0.2993	0.6715	1.6916	0.3519	0.6747	2.4941	0.3884	1.0414	2.2740
hydroxycarbamate NIST	1.1734	0.9699	0.7399	1.0815	1.0482	0.8847	1.0582	1.0115	0.9354	1.0760	1.1255	0.8404
hydroxylamine	0.8969	0.8508	1.0319	1.0149	1.1486	0.7650	1.0152	0.8476	1.0440	1.0329	1.2270	1.0570
hypoxanthine	0.5892	0.5259	0.7294	0.7643	0.9811	1.6110	0.8362	0.7855	1.4438	0.2863	1.3755	1.8762
indole-3-acetate	0.8167	1.1703	1.3931	0.7514	0.9056	1.2883	0.5888	0.9987	1.5463	0.7273	0.8744	1.0780
indole-3-lactate	0.8593	1.0667	1.0915	0.7023	0.8909	1.0522	0.9314	1.0887	1.3092	0.8409	0.9889	1.2683
indoxyl sulfate	0.8913	1.2251	1.0039	0.9982	1.1422	0.9649	0.7833	0.7890	0.9281	1.0578	0.9746	1.2387
inosine	0.5554	0.3210	0.9488	0.9198	0.7233	1.8744	0.8195	0.4797	2.0667	0.6445	1.0784	1.3327
isocitric acid	1.1031	1.3534	0.7624	0.9698	1.0466	0.6506	0.9847	1.3322	0.8151	1.0687	1.1129	0.8621
isohexonic acid	0.8650	1.0970	0.9791	0.8792	0.8943	1.0763	0.9271	0.8258	1.0180	1.0294	1.0710	1.3363
isoleucine	0.9279	0.9205	1.0334	0.9011	0.8604	1.1317	0.8392	0.8151	1.0995	1.1582	1.0908	1.1789
isothreonic acid	1.2552	1.1393	0.8081	1.0594	0.8783	0.6971	1.1418	1.2943	0.8004	1.0959	1.0711	0.8259
lactamide	1.2581	1.2878	0.8795	1.2093	0.8130	1.2936	0.7846	1.1619	0.8295	0.9559	0.8662	0.7085
lactic acid	1.0500	1.1634	1.0887	1.0434	1.0463	1.1974	0.7899	1.0383	0.8746	0.9551	0.8225	0.9699
lauric acid	1.2315	0.9362	0.8287	1.1252	1.2503	0.7234	1.1656	1.0002	0.8414	1.1136	0.9795	0.7716
leucine	0.9457	0.9512	1.0826	0.8800	0.8353	1.2551	0.8470	0.8326	1.0414	0.9925	1.0839	1.2416
linoleic acid	1.3158	0.8751	0.5385	0.9510	1.1844	0.3626	1.7219	1.6383	0.6155	1.2573	1.0993	0.4196
lysine	1.0497	0.9755	1.0146	0.6835	0.8172	1.1332	1.1020	0.9445	1.3339	0.8747	0.9937	1.1672
lyxitol	0.8632	1.0216	1.2433	0.6663	0.8512	1.1617	0.7910	1.0045	1.3754	0.8607	0.9385	1.3309
lyxose	0.6757	1.4150	1.3928	0.5761	1.2352	0.7566	0.5672	1.1162	1.0739	0.7473	1.0543	1.5752
malic acid	0.9429	1.4706	1.1844	0.9255	1.0210	1.0820	0.8690	1.1479	1.0619	0.7269	0.8501	0.8832
mannitol	0.6842	1.8753	0.8914	0.6074	1.1532	0.9854	0.9311	1.0629	1.2119	0.6217	0.9261	1.2422
mannose	1.2432	0.9216	0.7388	1.4182	1.1367	0.3480	1.4608	1.0463	0.5054	1.5116	1.1341	0.4278
methanolphosphate	1.0235	0.7532	1.1374	0.8508	1.2447	0.7889	1.2522	0.5739	1.1730	0.9838	1.3019	0.8742
methionine	0.9435	0.8366	1.2263	0.9624	0.7489	1.3493	1.0783	0.6348	1.1604	0.9573	0.8850	1.2344
methionine sulfoxide	0.8608	0.8600	1.0476	1.0970	0.9890	1.2382	0.7664	0.7623	1.0282	0.9550	0.9653	1.3510
myo-inositol	0.8241	0.9989	1.1030	0.8174	0.9335	1.1172	0.8261	0.9495	1.1618	0.9777	1.0472	1.2492
myristic acid	1.1264	0.8280	0.8069	0.9485	1.2143	0.5558	1.3392	1.4124	0.8009	1.1080	1.1891	0.6281
n-acetylglutamate	1.2128	0.8213	0.8210	0.8740	1.0841	0.6028	0.8551	1.1218	1.0049	1.0569	1.2801	1.2580
N-acetylglycine NIST	1.9507	1.0254	0.5486	1.6357	1.1035	0.2871	1.5475	0.7245	0.2653	1.7001	0.8957	0.2998
N-methylalanine	1.2807	1.0200	1.1021	1.2792	0.8425	0.7883	1.5501	0.8607	0.8032	1.1741	0.8187	0.5638
oleic acid	1.2757	0.8639	0.6060	0.9521	1.2202	0.3143	1.6786	1.7726	0.5703	1.2394	1.0863	0.4096
ornithine	0.7088	0.7481	1.1044	0.7971	0.8610	1.3894	0.7338	0.7831	1.4269	0.8101	0.9262	1.6740
oxalic acid	1.0869	0.9118	0.8102	1.7018	1.0120	0.5785	0.9683	1.1468	0.8621	1.3663	0.8915	0.5403
oxoproline	0.9159	1.0277	1.0253	0.9749	1.1948	0.8568	1.0164	0.8359	0.9489	1.0375	1.1484	0.9770
palmitic acid	1.0577	0.8803	0.8440	1.0388	1.1390	0.7216	1.1693	1.1964	0.8436	1.0940	1.1637	0.7889
palmitoleic acid	1.2625	0.9905	0.5111	0.8383	1.4465	0.2324	1.7350	1.9719	0.5138	1.0282	1.2406	0.2254
pelargonic acid	1.4754	0.9843	0.8733	1.0785	1.0438	0.7620	1.1439	0.9129	0.9498	1.0512	0.9363	0.8653
pentadecanoic acid	0.6534	0.9093	0.9034	1.0648	1.1359	0.7819	1.2277	1.2774	1.0034	0.9863	1.1347	0.8156
phenylalanine	0.8296	0.8508	1.1037	0.7923	0.7413	1.1959	0.9251	0.8602	1.3880	0.9721	0.9679	1.3923
phosphate	1.3558	1.0795	0.8888	1.0402	1.1368	0.6546	1.2807	0.9919	0.6140	1.1635	1.1551	0.6681
phosphoethanolamine	1.0616	0.7122	0.8672	1.1348	1.1553	0.9687	1.0085	0.6170	0.9256	1.1479	1.0354	1.2321
pinitol	0.1871	1.1262	1.3580	0.1435	0.7426	1.6320	0.2340	1.1190	2.3011	0.4532	0.7725	2.0853
proline	0.6984	0.6663	1.3317	0.6219	0.6055	1.7351	0.6969	0.5912	1.4254	0.7254	0.9500	1.9619
pseudo uridine	1.1583	1.0993	0.8382	0.9022	1.1884	0.6675	1.0418	1.2230	0.7044	1.0704	1.2333	0.8789
p-tolyl glucuronide	1.7240	0.8963	0.4916	2.0579	0.9335	0.3577	1.2518	0.8504	0.2297	1.9402	0.9092	0.1766
pyruvic acid	1.0385	0.6136	1.0337	0.9416	0.7557	1.1807	1.1147	1.1148	1.2039	0.9982	0.8763	1.1174
ribose	0.7532	0.8682	1.0782	1.3375	0.9838	0.7940	1.0384	0.6652	1.0627	0.9882	1.0280	1.3305
saccharic acid	0.8339	1.0881	0.9947	0.9390	0.8408	1.0460	0.9436	0.9108	1.0285	1.0193	1.0689	1.2869
salicylic acid	0.7464	1.7046	0.7312	1.6496	0.7005	0.7310	0.6268	0.8239	0.6558	1.4642	1.4636	0.5646
serine	0.9890	0.7641	1.2522	0.9272	0.7154	1.2840	1.0095	0.7370	1.3241	0.8061	0.8223	1.4443
sorbitol	0.7401	1.2497	1.1945	1.0066	1.2338	1.0753	0.7905	0.9463	0.9610	0.9090	0.8991	1.0043
stearic acid	0.9704	0.8660	0.8945	1.1039	1.0959	0.8221	1.0794	1.0071	0.8966	1.0391	1.1555	0.9884
succinic acid	0.9883	1.5201	1.0783	0.8558	0.9590	1.1396	0.9719	1.1125	0.9804	0.8304	0.8431	0.8804
sucrose	0.6338	0.5709	2.3790	0.6041	0.8457	1.9538	0.5843	0.7922	0.7533	0.8952	0.7166	1.3658
taurine	1.0468	0.8675	0.9827	1.2806	1.0607	1.0270	1.0151	0.9597	0.8672	1.2325	0.8653	0.7001
threonic acid	1.1909	0.8390	0.8085	1.2868	1.0712	0.7447	1.1455	0.9835	0.7279	1.3801	0.9718	0.7475
threonine	0.8655	0.8354	1.1785	1.0990	0.6908	1.3750	0.8605	0.6778	1.4345	0.8980	0.8321	1.2503
thymidine	1.1196	0.7576	0.9153	1.1239	0.7059	1.0589	1.1189	1.1616	0.6326	1.2926	1.3769	0.6086
tocopherol alpha-	0.9410	0.8454	1.0979	1.0028	0.9844	0.7503	1.3056	1.1780	1.3134	1.0166	0.8612	0.7482
tryptophan	0.7918	0.8970	1.1860	0.8239	0.8615	1.2104	0.8251	0.8957	1.5112	0.7471	1.0422	1.2398
tyrosine	0.8091	0.7851	1.1805	0.7619	0.6080	1.5356	0.8706	0.7064	1.4707	0.8442	0.8313	1.6288
uracil	1.2426	1.2507	0.9871	1.1462	0.8073	0.8751	0.9124	1.2526	0.5874	1.0687	1.0687	0.8869
urea	1.0634	1.0320	1.0104	0.8964	0.9166	0.8709	1.2400	1.0305	0.9720	1.0358	1.0072	0.9880
uric acid	1.4956	0.8942	0.9206	1.3503	0.9463	0.6861	1.0566	0.8111	0.7128	1.2099	0.8783	1.0782
uridine	1.2149	0.8729	0.8805	1.2890	1.1817	0.8132	1.0295	1.0579	0.6576	1.1223	1.0439	0.7563
valine	0.8244	0.8949	1.1278	0.8009	0.8153	1.3712	0.7118	0.7768	1.2729	0.9594	1.0980	1.3137
xanthine	0.8191	0.5386	0.8173	1.1336	1.0955	1.0713	1.0201	0.8901	1.2118	0.4336	1.3553	1.4613
xylitol	1.7042	1.0248	0.9403	1.0376	0.8419	0.8151	1.0112	1.0159	0.8266	1.0939	0.9515	0.8919
xylose	0.6475	1.6234	1.0783	0.6652	0.8974	0.5276	0.5671	1.3468	1.8233	0.5289	0.9983	1.5846
xylulose NIST	0.8654	0.8580	1.0934	1.1063	0.9666	1.2879	0.8518	0.7203	1.0754	0.9851	1.0280	1.0690

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Factors:

F1	Treamtent group:Sirt1+6 OE - 16h fast
F2	Treamtent group:Sirt1+6 OE - 4h fast
F3	Treamtent group:Sirt1+6 OE - fed
F4	Treamtent group:Sirt1 OE - 16h fast
F5	Treamtent group:Sirt1 OE - 4h fast
F6	Treamtent group:Sirt1 OE - fed
F7	Treamtent group:Sirt6 OE - 16h fast
F8	Treamtent group:Sirt6 OE - 4h fast
F9	Treamtent group:Sirt6 OE - fed
F10	Treamtent group:WT - 16h fast
F11	Treamtent group:WT - 4h fast
F12	Treamtent group:WT - Fed