Data for (Study ST001749)

(Analysis AN002848)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4
1-methyl-4-imidazoleacetate 1.0013 0.9535 1.0472 0.9942
1-methylnicotinamide 0.8399 0.9291 1.0286 1.1832
1-methylurate 1.1764 0.8945 1.2672 0.6684
1-ribosyl-imidazoleacetate* 0.9091 0.8956 1.1537 1.0253
2-aminobutyrate 1.0793 1.0461 0.9339 0.9511
2-aminoheptanoate 0.9226 1.1260 0.9769 0.9786
2-hydroxyglutarate 1.0102 1.0587 0.9766 0.9602
2-methylbutyrylcarnitine (C5) 0.9715 0.8841 0.9447 1.1807
2-methylbutyrylglycine 0.9085 1.1790 0.8720 1.0752
2-methylmalonylcarnitine (C4-DC) 0.9848 1.0293 1.0262 0.9632
2-methylserine 1.1229 0.7200 1.0729 1.0587
2^-O-methylcytidine 1.0745 0.8868 1.0009 1.0158
2-oxoarginine* 0.9808 0.8342 0.9224 1.2472
2-piperidinone 0.8526 1.4740 1.0293 0.6713
3-aminoisobutyrate 1.0230 1.0362 0.9627 0.9830
3-(cystein-S-yl)acetaminophen* 1.4683 0.9878 NA 0.5439
3-hydroxybutyroylglycine** 1.1699 1.1137 0.9447 0.7954
3-hydroxybutyrylcarnitine (1) 1.0961 1.4476 0.8306 0.6710
3-hydroxybutyrylcarnitine (2) 1.1509 1.0880 0.9017 0.8784
3-hydroxystachydrine* 1.0235 0.6304 1.4405 0.8358
3-methoxytyrosine 0.9804 0.9295 1.1162 0.9663
3-methylcytidine 0.9513 1.0426 0.9912 1.0144
3-methylglutarylcarnitine (2) 1.1293 0.9963 0.9701 0.9149
3-phosphoglycerate 0.6282 1.6255 0.7182 1.0183
3-ureidopropionate 0.9295 1.0511 1.0482 0.9478
4-acetamidophenol 1.5146 1.3241 0.4090 0.7642
4-guanidinobutanoate 0.8457 0.6677 1.0005 1.4179
4-hydroxyglutamate 0.8709 0.6843 1.1894 1.1757
5-(galactosylhydroxy)-L-lysine 1.0103 0.9173 1.1367 0.9296
5-hydroxyindoleacetate 0.8892 0.9389 1.0456 1.1317
5-hydroxylysine 1.0212 0.9477 0.9830 1.0455
5-methylthioadenosine (MTA) 1.0161 0.9587 1.0484 0.9747
7-methylguanine 0.9784 1.0004 1.0090 1.0105
7-methylxanthine 1.2041 0.6315 1.2881 0.8501
acetoacetate 1.1001 1.3948 0.8329 0.7135
acetylcarnitine (C2) 1.0095 1.0985 0.9419 0.9591
adenine 0.9992 1.0981 1.0015 0.9093
adenosine 0.8102 1.2903 0.9043 0.8585
adenosine 5^-monophosphate (AMP) 0.5009 1.6601 0.8073 1.0451
adipoylcarnitine (C6-DC) 1.1327 1.1800 0.7932 0.9179
alanine 0.9929 0.9522 1.0731 0.9773
alliin 0.6102 0.4831 1.4371 1.3455
anthranilate 1.0719 1.0215 0.7425 1.0465
argininate* 1.0935 0.8967 0.8750 1.1340
arginine 1.0193 0.9610 1.0187 0.9993
argininosuccinate 0.8847 1.0540 1.0545 1.0169
asparagine 1.0031 0.9566 1.0165 1.0204
aspartate 0.7695 1.3681 0.8615 1.0124
atenolol NA NA 0.7849 1.2151
benzoylcarnitine* 0.8496 0.9035 1.0220 1.2094
beta-alanine 1.0083 0.9217 1.0200 1.0442
betaine 1.0462 1.0015 0.9879 0.9683
betonicine 1.1738 0.7308 1.0276 1.0375
butyrylcarnitine (C4) 1.0974 1.1691 0.8471 0.9086
caffeine 0.9130 0.7984 1.5412 0.7221
carboxyethyl-GABA 1.0245 1.0433 0.9935 0.9443
carnitine 1.0244 0.9558 0.9862 1.0319
choline 1.0799 0.9743 0.9741 0.9762
choline phosphate 0.7762 1.3090 0.8930 1.0289
citramalate 0.9420 0.9880 1.1376 0.9309
citrulline 1.0191 1.0059 0.9788 0.9983
cotinine 1.2342 1.6357 0.0035 0.0226
creatine 1.0326 0.9469 0.9709 1.0479
creatinine 0.9909 0.9539 1.0447 1.0059
cys-gly, oxidized 0.9100 0.9563 0.9933 1.1293
cystathionine 0.7760 0.7889 1.1009 1.3063
cysteine 0.9997 1.0696 0.9799 0.9566
cysteine-glutathione disulfide 0.9402 1.2487 0.9072 0.9196
cysteine s-sulfate 1.0054 1.1401 0.8456 1.0211
cysteine sulfinic acid 1.0720 1.0335 0.9097 0.9861
cysteinylglycine 0.9596 1.0346 1.0179 0.9874
cysteinylglycine disulfide* 1.0025 0.9952 0.9941 1.0080
cystine 1.0702 1.1334 0.7129 1.1006
cytidine 1.0023 1.2481 1.0466 0.7239
cytosine 0.8220 0.8956 1.3410 0.9144
deoxycarnitine 1.0394 0.9768 0.9630 1.0222
dimethylarginine (SDMA + ADMA) 1.0120 0.9887 1.0012 0.9982
dimethylglycine 1.0753 1.0043 0.9499 0.9771
dimethyl sulfone 1.1322 1.4601 0.7648 0.6923
ectoine 0.6388 0.6555 1.1490 1.4978
ergothioneine 0.9583 0.9449 1.1370 0.9518
formiminoglutamate 1.2619 1.5338 0.5146 0.7560
gamma-carboxyglutamate 0.9236 1.0158 1.0129 1.0426
gamma-glutamyl-2-aminobutyrate 1.1053 1.1429 0.8815 0.8930
gamma-glutamylalanine 0.9369 0.9785 1.2099 0.9052
gamma-glutamyl-alpha-lysine 1.0749 0.9818 0.9682 0.9799
gamma-glutamylcitrulline* 1.0181 1.0960 0.8871 1.0083
gamma-glutamyl-epsilon-lysine 1.0525 0.9779 1.0006 0.9715
gamma-glutamylglutamate 1.0265 1.0224 0.9366 1.0186
gamma-glutamylglutamine 0.9893 1.0237 0.9925 0.9956
gamma-glutamylglycine 1.0048 0.9445 1.0426 1.0039
gamma-glutamylhistidine 0.9011 0.8905 1.1377 1.0534
gamma-glutamylisoleucine* 0.9610 0.9106 0.9852 1.1326
gamma-glutamylleucine 0.9860 0.9590 0.9505 1.0999
gamma-glutamylmethionine 1.0771 1.0157 0.9409 0.9741
gamma-glutamylphenylalanine 1.0045 0.9889 0.9683 1.0377
gamma-glutamylthreonine 1.0268 0.9380 1.0417 0.9906
gamma-glutamyltryptophan 1.0402 1.0661 0.9736 0.9289
gamma-glutamyltyrosine 1.0232 1.0331 0.9512 0.9959
gamma-glutamylvaline 0.8974 0.9990 1.0174 1.0776
glutamate 0.9352 1.1187 0.9138 1.0367
glutamine 0.9980 0.9922 1.0078 1.0012
glutarylcarnitine (C5-DC) 1.0337 0.9425 1.0491 0.9728
glycerol 3-phosphate 1.1559 0.7311 1.0649 1.0386
glycerophosphoethanolamine 0.9172 1.1954 0.9426 0.9542
glycerophosphorylcholine (GPC) 1.0381 0.9946 1.0522 0.9179
glycine 1.0055 0.9461 1.0508 0.9935
hexanoylcarnitine (C6) 1.0718 1.0424 0.9897 0.9057
histidine 1.0073 0.9800 0.9837 1.0280
homoarginine 0.9897 1.0509 0.9222 1.0406
homocitrulline 0.9274 0.9109 0.9007 1.2476
homostachydrine* 1.0918 1.0919 0.7148 1.1168
hydroxyasparagine** 0.9735 0.9905 1.0243 1.0087
hypotaurine 0.7244 1.4241 0.8967 0.9672
imidazole lactate 1.1634 0.8611 1.0084 0.9691
imidazole propionate 0.9578 1.3290 0.7924 0.9549
iminodiacetate (IDA) 1.1967 0.7824 1.2010 0.8182
indoleacetylcarnitine* 0.7811 0.9689 0.9123 1.3168
indoleacetylglutamine 0.6687 0.6964 1.2977 1.2842
indolin-2-one 1.3372 0.9366 0.6285 1.1040
isobutyrylcarnitine (C4) 1.0805 0.8591 1.0074 1.0480
isoleucine 1.0050 0.9698 1.0014 1.0217
isovalerylcarnitine (C5) 1.1456 0.9602 0.8563 1.0467
kynurenine 0.9319 0.9336 1.0261 1.0973
lamotrigine 0.8316 2.4662 NA 0.0390
lanthionine 0.9297 0.7535 0.9025 1.2813
leucine 0.9948 0.9616 0.9748 1.0653
leucylglycine 0.7778 1.2403 0.9430 0.9699
levetiracetam 0.0287 NA 2.4703 0.0021
lysine 1.0428 0.9993 0.9744 0.9870
malonylcarnitine 1.0260 0.9006 1.0622 1.0072
methionine 1.0436 0.9576 0.9978 1.0011
methionine sulfone 0.9406 0.9101 1.1455 0.9915
methionine sulfoxide 1.0721 0.9445 0.9714 1.0133
methyl indole-3-acetate 0.8618 0.9524 1.0590 1.1113
methylsuccinoylcarnitine 0.8450 0.7981 1.1733 1.1538
N1-Methyl-4-pyridone-3-carboxamide 0.8410 0.9645 1.0449 1.1334
N1-methyladenosine 1.0114 1.0021 0.9919 0.9958
N1-methylinosine 0.8573 1.1033 0.9624 1.0737
(N(1) + N(8))-acetylspermidine 0.9867 0.9800 1.0435 0.9870
N2,N2-dimethylguanosine 0.9871 0.9296 1.0630 1.0133
N6,N6,N6-trimethyllysine 1.0713 0.8817 0.9601 1.0829
N-acetyl-1-methylhistidine* 0.8570 0.7879 1.2005 1.1298
N-acetyl-3-methylhistidine* 0.8079 0.7163 1.2787 1.1622
N-acetylalliin 0.6208 0.3780 1.7454 1.0436
N-acetylarginine 0.9957 0.9728 0.9437 1.0852
N-acetyl-aspartyl-glutamate (NAAG) 1.0495 0.9816 0.9761 0.9980
N-acetylcarnosine 0.9183 0.9173 1.1014 1.0493
N-acetylglucosamine/N-acetylgalactosamine 0.9988 1.0459 0.9660 0.9930
N-acetylglucosaminylasparagine 0.8620 1.0426 1.0349 1.0526
N-acetylglutamate 0.9957 1.0234 1.0479 0.9345
N-acetylglycine 0.9849 1.0661 1.0680 0.8853
N-acetyl-isoputreanine* 1.0501 0.9853 1.0102 0.9573
N-acetylneuraminate 0.8515 1.1148 0.9674 1.0634
N-acetylputrescine 0.9844 0.9958 1.0049 1.0132
N-alpha-acetylornithine 0.9995 0.9476 1.0359 1.0051
N-carbamoylalanine 1.2228 0.6847 0.9173 1.0760
nicotinamide 0.6351 1.4523 0.8651 1.0548
nicotinamide riboside 0.8945 1.0075 0.9352 1.1575
N-methylhydroxyproline** 1.1771 0.8026 1.2092 0.7318
N-methylpipecolate 0.9521 1.0050 0.9067 1.1327
N-methylproline 1.3460 0.6967 1.1476 0.8133
N,N,N-trimethyl-5-aminovalerate 0.9825 0.8946 1.0737 1.0389
O-desmethyltramadol 0.8488 1.4535 NA NA
O-desmethylvenlafaxine 1.5702 0.8565 0.0031 NA
ornithine 1.0156 0.9912 0.9640 1.0298
phenylacetylcarnitine 1.2352 0.9693 0.7024 1.1102
phenylalanine 0.9976 0.9747 0.9963 1.0291
phenylalanylalanine 1.0164 0.9211 0.8929 1.1402
phenylalanylglycine 1.0218 1.0046 0.8941 1.0747
phosphate 0.9868 0.9897 0.9951 1.0264
phosphoethanolamine 0.7021 1.5293 0.8239 0.9640
picolinate 0.9027 0.8963 1.0126 1.1717
pimeloylcarnitine/3-methyladipoylcarnitine (C7-DC) 1.1949 0.8987 1.0834 0.8308
pipecolate 0.8413 0.9547 1.3155 0.8715
pro-hydroxy-pro 1.0032 0.9429 1.0314 1.0180
proline 1.0175 0.9850 0.9665 1.0312
prolylglycine 1.1941 0.8459 0.9137 1.0497
propionylcarnitine (C3) 1.1009 0.9382 0.9066 1.0575
pyroglutamine* 1.0437 1.0324 0.9920 0.9383
pyrraline 1.0876 1.0052 1.0126 0.9027
quinolinate 0.8402 0.8806 1.0634 1.1925
S-1-pyrroline-5-carboxylate 1.0390 0.9419 1.0746 0.9429
S-allylcysteine 0.6629 0.5236 1.0945 1.5285
sarcosine 1.2206 0.7426 1.1845 0.8493
serine 1.0518 1.0071 0.9781 0.9679
serotonin 0.3742 0.9631 0.4497 2.1394
S-methylcysteine sulfoxide 0.9709 0.8668 1.2012 0.9476
S-methylmethionine 0.7418 0.8855 1.3393 1.0592
spermidine 0.5139 1.3038 1.0681 1.0906
stachydrine 1.2164 0.6699 1.2860 0.8182
suberoylcarnitine (C8-DC) 0.8544 0.9155 1.0854 1.1370
succinylcarnitine (C4-DC) 1.0556 1.0434 0.9525 0.9527
taurine 0.8199 1.3118 0.9177 0.9616
theobromine 1.1240 0.8516 1.0906 0.9256
thioproline 1.0433 1.0191 1.0009 0.9419
threonine 1.0441 0.9512 0.9954 1.0089
tiglylcarnitine (C5:1-DC) 0.9406 0.9272 1.0168 1.1044
trans-4-hydroxyproline 1.0936 0.8743 1.0071 1.0223
trans-urocanate 1.2058 0.8983 0.9498 0.9422
trazadone 1.6617 1.1095 0.9520 0.7749
trigonelline (N^-methylnicotinate) 1.0620 1.1566 1.0421 0.7575
trimethylamine N-oxide 1.0909 0.8944 0.7933 1.2202
tryptophan 0.9432 0.9820 1.0094 1.0592
tryptophan betaine 1.4148 0.8765 0.6944 1.0386
tyrosine 0.9990 0.9961 0.9683 1.0363
urea 0.9721 0.9684 0.9755 1.0789
valine 1.0084 0.9802 0.9436 1.0669
valylglycine NA 1.1316 0.6051 NA
valylleucine 1.0588 1.0820 0.8440 1.0269
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Factors:

F1Treatment:Enhanced Physical Activity | Timepoint:Post
F2Treatment:Enhanced Physical Activity | Timepoint:Pre
F3Treatment:Usual Physical Activity | Timepoint:Post
F4Treatment:Usual Physical Activity | Timepoint:Pre
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