Data for (Study ST001833)
(Analysis AN002975)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylornithine | 0.8188 | 1.4205 | 0.7737 | 1.6510 | 1.2744 | 1.1593 | 0.0600 | 0.5674 | 1.0711 | 0.5502 | 0.2208 | 0.6680 | 1.3770 | 0.3004 | 1.4990 | 0.9439 | 1.3041 | 1.8023 |
Alanine | 0.3092 | 0.1357 | 0.2206 | 0.7238 | 0.3917 | 0.2124 | 0.0686 | 0.7873 | 0.5131 | 1.4137 | 1.5957 | 1.3658 | 1.3651 | 1.4143 | 1.4064 | 1.2899 | 2.2591 | 2.2384 |
Alpha- Aminoadipic acid | 0.2312 | 0.2523 | 2.6431 | NA | NA | 1.8909 | 0.2799 | 0.3120 | 0.4085 | 0.9690 | 1.0738 | 0.9138 | 1.3817 | 0.7016 | 0.7937 | 0.7306 | 1.4907 | 1.1983 |
Arginine | 0.6687 | 0.5481 | 0.4570 | 0.6087 | 0.8954 | 0.3991 | 0.2015 | 0.5597 | 0.6046 | 1.2155 | 1.0035 | 1.0690 | 1.1508 | 0.9675 | 1.3659 | 1.9637 | 2.5381 | 1.7353 |
Asparagine | 0.1101 | 0.1364 | 0.2863 | NA | 0.6083 | 0.2650 | 0.0959 | 0.1395 | 0.2311 | 1.5217 | 1.2699 | 1.2978 | 1.8165 | 1.2716 | 1.3721 | 1.3668 | 1.8159 | 1.1478 |
Aspartate | 1.1761 | 1.1977 | 0.8370 | 3.3984 | 1.9751 | 1.3330 | 0.4579 | 1.7070 | 2.1749 | 0.5120 | 0.7719 | 0.6267 | 0.2645 | 0.7287 | 0.2698 | 0.4245 | 0.8910 | 0.5723 |
Asymmetric dimethylarginine | 0.3594 | 1.5847 | 1.2288 | 3.6863 | 1.4101 | 1.8041 | 0.5413 | 1.8921 | 0.6570 | 0.4270 | 0.3965 | 0.6001 | NA | 0.4317 | 0.6589 | 0.3165 | 1.5158 | 0.4877 |
Carnosine | 1.0429 | 4.4081 | 0.8541 | 1.9187 | 1.9978 | 1.6065 | 0.4711 | 2.2013 | 0.7146 | 0.5344 | 0.3578 | 0.6440 | 1.0086 | 0.3875 | 0.5395 | 0.3780 | 0.4273 | 0.4508 |
cis-4-Hydroxyproline | NA | 8.1454 | 0.0719 | 0.3085 | NA | 0.0390 | 0.0138 | 2.8746 | 0.0018 | 0.0087 | 0.0100 | 0.0079 | NA | 1.8822 | 0.0068 | 0.0041 | 0.9283 | 0.0036 |
Citrulline | 0.8834 | 0.1956 | 0.6836 | 1.5959 | 1.0408 | 0.3976 | 0.0311 | 0.4425 | 0.6866 | 0.9463 | 1.0082 | 1.0169 | 1.0160 | 0.8861 | 1.1142 | 1.1807 | 2.2559 | 2.1209 |
Creatinine | 0.0187 | 1.3191 | 0.0113 | 0.0951 | 0.0944 | 0.0239 | 0.3110 | 0.3109 | 0.7000 | 1.5894 | 1.6169 | 1.4154 | 0.9400 | 1.5546 | 1.2763 | 1.5384 | 1.2234 | 1.3042 |
Dihydroxyphenylalanine | 0.6180 | 0.5258 | 0.9337 | 2.7621 | 2.6043 | 2.2022 | 0.4159 | 3.0687 | 1.3176 | 0.3737 | 0.3875 | 0.3793 | 0.2698 | 0.3502 | 0.4114 | 0.4116 | 0.4252 | 0.4044 |
Dopamine | 0.8551 | 2.2908 | 0.7008 | NA | 1.2570 | 1.0928 | 0.9680 | 1.3555 | 1.0210 | 0.9389 | 0.8765 | 0.8585 | NA | 0.8527 | 0.8500 | 0.8855 | 0.8291 | 0.8705 |
Glutamate | 1.1325 | 0.4892 | 0.8277 | 1.6277 | 0.8525 | 1.0197 | 0.3437 | 0.6604 | 1.2523 | 1.2507 | 1.2124 | 0.9446 | 0.9785 | 1.0873 | 0.7562 | 1.0418 | 1.3067 | 1.0881 |
Glutamine | 0.0485 | 0.0342 | 0.0252 | NA | 0.0522 | 0.0217 | 0.0232 | 0.0238 | 0.1546 | 1.6152 | 1.8026 | 2.0540 | NA | 1.8444 | 2.0734 | 2.1727 | 1.7175 | 1.7447 |
Glycine | 0.6207 | 0.6597 | 0.5856 | 0.5844 | 0.6647 | 0.6103 | 0.5268 | 1.1459 | 0.9914 | 1.1978 | 1.3669 | 1.5064 | 1.3050 | 1.1540 | 1.2255 | 1.3048 | 1.2560 | 1.1939 |
Histamine | 0.6125 | 1.6659 | 0.7786 | 0.7423 | 0.9796 | 3.2747 | 0.7255 | 0.9167 | 0.6979 | 0.7448 | 0.9282 | 0.7580 | 0.6372 | 0.8646 | 0.9214 | 0.8570 | 0.7962 | 0.7459 |
Histidine | 0.0977 | 0.1452 | 0.1032 | 0.1252 | 0.2004 | 0.1257 | 0.0639 | 0.3456 | 0.3717 | 1.6799 | 1.6378 | 1.7277 | 1.8573 | 1.5059 | 1.7590 | 1.7290 | 2.3413 | 1.9798 |
Isoleucine | 0.1182 | 0.7617 | 0.2376 | 0.3070 | 0.3874 | 0.4854 | 0.1696 | 0.5928 | 0.3373 | 1.8990 | 1.9978 | 1.9486 | NA | 1.7266 | 1.8005 | 1.9088 | 2.1432 | 1.5819 |
Kynurenine | 1.7420 | 1.4594 | 0.1687 | NA | 0.7135 | 0.9175 | 0.0558 | 0.1520 | 0.5847 | 0.8629 | 0.8788 | 0.8129 | 0.6931 | 0.9996 | 0.6504 | 0.7945 | 4.5817 | 0.2863 |
Leucine | 0.1349 | 0.6704 | 0.2303 | 0.2122 | 0.1448 | 0.2474 | 0.1476 | 1.3656 | 0.4238 | 1.8023 | 1.8638 | 1.7290 | NA | 1.5867 | 1.6209 | 1.7557 | 1.8504 | 1.4623 |
Lysine | 0.4658 | 0.2026 | 0.2898 | 0.6027 | 0.5569 | 0.2633 | 0.0906 | 0.3761 | 0.6628 | 2.1145 | 1.9676 | 2.1380 | 2.2223 | 1.7762 | 1.8878 | 1.8322 | 1.7690 | 1.8554 |
Methionine | 0.8917 | 0.4414 | 0.7051 | 1.2947 | 1.1756 | 0.5933 | 0.1304 | 1.1880 | 0.7082 | 1.2069 | 1.0584 | 1.3471 | 1.6394 | 1.0209 | 1.1502 | 0.9336 | 1.1512 | 1.1332 |
Methioninesulfoxide | 1.6744 | 1.3300 | 1.1298 | 2.1071 | 2.2993 | 1.0839 | 0.1112 | 1.1231 | 1.7945 | 0.9692 | 0.3156 | 0.5997 | 0.7855 | 0.3408 | 0.6852 | 0.3996 | 0.4283 | 0.5932 |
Nitrotyrosine | 1.1797 | 3.7911 | 0.6205 | 1.1647 | 0.9094 | 2.1424 | 0.2421 | 1.0897 | 0.4328 | 0.1577 | 0.2544 | 0.1933 | 0.1410 | 4.8561 | 0.2834 | 0.2456 | 1.2903 | 0.2693 |
Ornithine | 0.1625 | 0.0299 | 0.0924 | 0.2672 | 0.1460 | 0.1440 | 0.0204 | 0.2016 | 0.4611 | 1.6010 | 1.4798 | 2.2776 | 1.5493 | 1.0925 | 1.5930 | 1.2744 | 2.7606 | 2.0535 |
Phenylalanine | 0.5422 | 0.2648 | 0.3706 | 0.7699 | 0.5971 | 0.2286 | 0.1044 | 1.2903 | 0.7534 | 1.4685 | 1.3525 | 1.4737 | 1.7236 | 1.2359 | 1.3776 | 1.3322 | 1.5218 | 1.4672 |
Phenylethylamine | 1.4269 | 3.2359 | 0.1933 | 0.3757 | 0.8136 | 0.8842 | NA | 3.9931 | 0.3580 | 0.0342 | NA | 0.0898 | 0.1191 | 5.2250 | 0.0928 | NA | 1.8702 | 0.1463 |
Proline | 0.2611 | 0.3130 | 0.1462 | 0.3899 | 0.3099 | 0.1271 | 0.0523 | 2.0044 | 1.1194 | 1.5310 | 1.2154 | 1.4062 | 2.1674 | 0.9610 | 1.1215 | 0.9174 | 1.6895 | 1.7819 |
Putrescine | 1.5820 | 1.2079 | 0.1124 | 0.1931 | 0.0953 | 0.1773 | 0.5051 | 7.2005 | 0.3341 | 0.1178 | 0.1672 | 0.1048 | 0.0173 | 1.5345 | 0.0997 | 0.1110 | 1.9685 | 0.2388 |
Serine | 0.2945 | 0.2211 | 0.1977 | 0.4842 | 0.4524 | 0.2092 | 0.1043 | 0.2954 | 0.2765 | 1.6748 | 2.0066 | 1.9042 | 1.4509 | 1.8292 | 1.6409 | 1.6531 | 2.7878 | 2.1723 |
Serotonine | 2.0898 | 3.6614 | 0.2028 | 0.0967 | 0.4737 | 0.3465 | 0.0815 | 1.1475 | 0.3887 | 0.3873 | 0.9872 | 0.4095 | NA | 1.7271 | 0.3345 | 0.0950 | 3.5301 | 0.7791 |
Spermidine | 0.5266 | 0.6159 | 0.6620 | NA | 0.5707 | 0.7072 | 0.9174 | 2.2491 | 0.7523 | 1.1462 | 1.3083 | 1.0126 | NA | 0.9990 | 1.1270 | 1.0265 | 0.7754 | 1.0453 |
Spermine | NA | NA | NA | NA | NA | NA | NA | 2.6737 | 0.7571 | NA | 0.1629 | 0.9990 | NA | 0.0383 | 0.4456 | NA | 1.1811 | 0.5343 |
Symmetric dimethylarginine | 0.2353 | 3.7489 | 0.3252 | 2.3255 | NA | 0.2647 | 0.4416 | 1.6395 | 0.7386 | 0.7912 | 0.7205 | 0.7829 | NA | 0.6088 | 0.8698 | 0.7525 | 0.7229 | 1.6646 |
Taurine | 0.3039 | 0.8860 | 0.2630 | 0.6938 | 0.2668 | 0.1342 | 0.0955 | 1.0469 | 0.4932 | 1.5966 | 1.9980 | 1.6145 | 1.4222 | 1.0850 | 1.6688 | 1.9286 | 1.5172 | 1.2944 |
Threonine | 0.4576 | 0.2335 | 0.2940 | 0.6698 | 0.6182 | 0.2140 | 0.1013 | 0.4071 | 0.5956 | 2.2453 | 2.2244 | 2.4517 | NA | 2.3031 | 1.9977 | 1.7198 | 1.2368 | 1.0405 |
trans-4-Hydroxyproline | 0.6800 | 2.6695 | 0.0827 | 0.1782 | 0.0757 | 0.1999 | 0.0819 | 0.8735 | 0.4345 | 1.0898 | 1.1235 | 1.2548 | 1.3418 | 1.5588 | 1.5239 | 1.2923 | 1.1821 | 1.1962 |
Tryptophan | 0.1055 | 0.1666 | 0.0770 | 0.1246 | 0.1660 | 0.0700 | 0.0551 | 0.1596 | 0.2793 | 1.9815 | 2.0798 | 2.0046 | 2.1070 | 1.9241 | 1.7938 | 2.0507 | 1.4291 | 1.5707 |
Tyrosine | 0.5193 | 0.2512 | 0.3680 | 0.8434 | 0.6931 | 0.2147 | 0.0881 | 1.0456 | 0.5050 | 1.4686 | 1.5205 | 1.4622 | 1.5306 | 1.3341 | 1.3383 | 1.3401 | 1.5878 | 1.7352 |
Valine | 0.3718 | 0.2256 | 0.2202 | 0.4630 | 0.5344 | 0.1643 | 0.0917 | 1.3836 | 0.7968 | 1.6110 | 1.4723 | 1.5230 | 1.9869 | 1.2716 | 1.4341 | 1.3585 | 1.5508 | 1.4524 |
Factors:
F1 | Tissue:Caecum | Sample treatment:DIO |
F2 | Tissue:Caecum | Sample treatment:DIO_AB |
F3 | Tissue:Caecum | Sample treatment:DIO_FMT_RYGB |
F4 | Tissue:Caecum | Sample treatment:DIO_PF_FMT |
F5 | Tissue:Caecum | Sample treatment:FMT_lean |
F6 | Tissue:Caecum | Sample treatment:Lean |
F7 | Tissue:Caecum | Sample treatment:Lean_AB |
F8 | Tissue:Caecum | Sample treatment:RYGB_AB |
F9 | Tissue:Caecum | Sample treatment:RYGB_Donor |
F10 | Tissue:Serum | Sample treatment:DIO |
F11 | Tissue:Serum | Sample treatment:DIO_AB |
F12 | Tissue:Serum | Sample treatment:DIO_FMT_RYGB |
F13 | Tissue:Serum | Sample treatment:DIO_PF_FMT |
F14 | Tissue:Serum | Sample treatment:FMT_lean |
F15 | Tissue:Serum | Sample treatment:Lean |
F16 | Tissue:Serum | Sample treatment:Lean_AB |
F17 | Tissue:Serum | Sample treatment:RYGB_AB |
F18 | Tissue:Serum | Sample treatment:RYGB_Donor |