Data for (Study ST001917)
(Analysis AN003115)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 2-Methylbutyrylcarnitine | NA | NA | NA | NA |
| Acetyl Carnitine | 0.6548 | 0.0942 | 1.6271 | 1.6238 |
| Adenine | 0.9462 | 1.1149 | 0.8873 | 1.0516 |
| Adenosine | 0.9805 | 1.0383 | 0.9603 | 1.0209 |
| ADP | 1.1414 | 0.9842 | 1.1614 | 0.7129 |
| Alanine | NA | NA | NA | NA |
| AMP | 0.9943 | 0.9916 | 1.0092 | 1.0050 |
| Arginine | NA | NA | NA | -0.3359 |
| Asparagine | 5.4815 | NA | 5.2197 | NA |
| Aspartic acid | NA | NA | NA | NA |
| Butyrylcarnitine | NA | NA | -1.9686 | -1.0753 |
| Carnitine | NA | NA | NA | NA |
| cis-aconitate | 0.7816 | 0.3035 | 1.6031 | 1.3118 |
| Citrate | 0.9800 | 0.7722 | 1.1589 | 1.0889 |
| Citrulline | NA | NA | NA | NA |
| Cytidine | 0.9931 | 1.0475 | 0.9165 | 1.0430 |
| Cytidine 5^-diphosphate | 0.9036 | 1.0857 | 0.8574 | 1.1533 |
| Cytidine 5 -Monophosphate | 0.9901 | 1.0411 | 0.9414 | 1.0275 |
| Cytosine | 1.0624 | 0.9992 | 0.9159 | 1.0226 |
| Deoxy carnitine | NA | NA | NA | NA |
| dGMP | 0.9687 | 0.9892 | 1.0060 | 1.0362 |
| Erythrose-4-P | 0.8050 | 1.4913 | 1.0791 | 0.6247 |
| Fumarate | 1.5262 | 1.7363 | NA | 1.4381 |
| G6P/F6P | 0.9378 | 0.9673 | 1.2243 | 0.8706 |
| GlucoseFructose | 0.9226 | 0.9926 | 1.0197 | 1.0651 |
| Glutamic acid | 1.0100 | 0.9904 | 0.9837 | 1.0158 |
| Glutamine | 1.0009 | 0.9775 | 1.0042 | 1.0174 |
| Glycerol 3 Phosphate | -0.1139 | NA | -21.9488 | -4.2638 |
| GMP | 1.0029 | 1.0156 | 0.9897 | 0.9918 |
| Guanine | 1.0443 | 1.0626 | 0.9393 | 0.9538 |
| Guanosine | 1.0568 | 1.0750 | 0.9186 | 0.9496 |
| Heptanoyl Carnitine | NA | NA | NA | NA |
| Histidine | NA | NA | NA | NA |
| Homocysteine | NA | NA | NA | NA |
| Homoserine | NA | NA | NA | NA |
| Hydroxy glutarate | 1.0258 | 0.9630 | 0.9630 | 1.0482 |
| Hypoxanthine | 1.0256 | 1.0116 | 0.9868 | 0.9760 |
| IMP | 1.0119 | 0.9893 | 1.0120 | 0.9868 |
| Inosine | 1.0104 | 1.0576 | 0.9688 | 0.9632 |
| Isobutyryl Carnitine | NA | NA | -1.9780 | -0.9655 |
| Isoleucine | 0.9926 | 0.9831 | 0.9947 | 1.0297 |
| Isovaleryl Carnitine | NA | NA | NA | NA |
| Ketoglutarate | 1.0142 | 0.9494 | 0.9349 | 1.1016 |
| Lactate | 1.0284 | 0.9221 | 1.0864 | 0.9631 |
| Lysine | NA | NA | NA | NA |
| Malate | 1.0197 | 1.0515 | 0.8969 | 1.0319 |
| Methionine | -0.8211 | NA | -0.1985 | NA |
| MethylGlutaryl carnitine | NA | NA | NA | NA |
| Octanoylcarnitine | NA | NA | NA | NA |
| Ornithine | NA | NA | NA | NA |
| Palmitoylcarnitine | NA | NA | NA | NA |
| Phenyl alanine | 1.0220 | 0.9794 | 1.0189 | 0.9796 |
| Proline | -0.9372 | NA | NA | NA |
| Propionyl Carnitine | NA | NA | 5.3030 | 7.2623 |
| Putrescine | NA | NA | NA | NA |
| Ribose/Ribulose/xylulose-5P | 1.0492 | 1.0312 | 0.9076 | 1.0121 |
| Serine | NA | NA | NA | NA |
| Spermidine | NA | NA | NA | NA |
| Spermine | NA | NA | NA | NA |
| Succinate | 0.9319 | 0.3499 | 1.5934 | 1.1248 |
| Succinyl CoA | NA | NA | NA | NA |
| Threonine | NA | NA | NA | NA |
| Tryptophan | 1.1881 | 0.8734 | 1.0847 | 0.8537 |
| Tyrosine | 3.6881 | NA | 1.6824 | NA |
| Uridine | 0.9861 | 1.0316 | 0.9732 | 1.0091 |
| Valine | NA | NA | NA | NA |
| Xanthine | 1.0381 | 0.9845 | 1.0103 | 0.9671 |
Factors:
| F1 | Group:KO_ZT18 | Genotype:Rev-erb cardiomyocyte specific knock out | Experimental variables:KO mouse heart ventrcle harvest at ZT18 |
| F2 | Group:KO_ZT6 | Genotype:Rev-erb cardiomyocyte specific knock out | Experimental variables:KO mouse heart ventrcle harvest at ZT6 |
| F3 | Group:WT_ZT18 | Genotype:wild type control | Experimental variables:WT mouse heart ventrcle harvest at ZT18 |
| F4 | Group:WT_ZT6 | Genotype:wild type control | Experimental variables:WT mouse heart ventrcle harvest at ZT6 |
