Data for (Study ST001978)
(Analysis AN003227)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 | F21 | F22 | F23 | F24 | F25 | F26 | F27 | F28 | F29 | F30 | F31 | F32 | F33 | F34 | F35 | F36 | F37 | F38 | F39 | F40 | F41 | F42 | F43 | F44 | F45 | F46 | F47 | F48 | F49 | F50 | F51 | F52 | F53 | F54 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| alanine | 0.7017 | 0.9169 | NA | 1.2655 | 0.1373 | 1.0301 | 1.2084 | 1.1552 | 1.3627 | 1.2226 | 1.1407 | 1.1369 | 0.5675 | 1.3133 | 1.5621 | 1.3935 | 1.3053 | 1.2026 | 1.1421 | 1.7921 | 2.0505 | 0.9349 | 1.4148 | 2.1986 | 1.1803 | 1.3803 | 1.3068 | 1.2283 | 1.4461 | 1.4314 | 0.1438 | 1.1528 | 1.0685 | 1.0341 | 0.9135 | 1.3733 | 1.0511 | 1.1506 | NA | 1.0828 | 0.1464 | 0.6950 | 1.1121 | 0.8820 | 1.1830 | 1.1667 | 1.0884 | 1.0954 | 1.2684 | 1.1859 | 0.1197 | 1.2484 | 1.2687 | 1.0044 |
| alanine-13C3-15N | 0.3990 | NA | NA | NA | 2.0478 | NA | 0.3437 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 2.2525 | NA | NA | NA | NA | NA | 0.5459 | 0.3411 | 0.3604 | NA | 2.4168 | NA | NA | NA | NA | NA | 0.4589 | 0.3550 | NA | NA | 2.0799 | NA | NA | NA |
| arginine | 0.6977 | 0.9666 | 0.8288 | 1.2302 | 0.2318 | 0.9348 | 0.6350 | 0.8043 | 1.1935 | 0.9910 | 1.4357 | 1.2138 | 0.7892 | 1.3931 | 1.6512 | 0.9582 | 0.9425 | 1.1842 | 0.9936 | 1.4860 | 1.5642 | 1.1639 | 1.4257 | 1.5361 | 1.0532 | 1.2113 | 1.1685 | 1.0200 | 1.0513 | 1.5005 | 0.1145 | 0.8898 | 0.7622 | 1.3271 | 1.1962 | 1.1949 | 1.2000 | 1.2394 | 1.0638 | 1.4280 | 0.1228 | 0.6324 | 1.6659 | 1.4120 | 1.6961 | 1.2323 | 1.1163 | 1.2460 | 1.3713 | 1.3301 | 0.1973 | 1.1987 | 2.0541 | 1.4006 |
| arginine-13C6-15N4 | 0.9350 | 0.6821 | 0.5387 | 1.1375 | 2.0151 | 1.1529 | 0.6926 | 0.7634 | 0.8480 | 0.8229 | 0.5234 | 0.6599 | 0.8576 | 0.6616 | 0.5515 | 0.6972 | 0.6634 | 0.6938 | 0.6740 | 0.7676 | 0.6684 | 0.7573 | 0.4985 | 0.4865 | 0.7789 | 0.6310 | 0.6448 | 0.6644 | 0.7791 | 1.2474 | 1.2295 | 1.3444 | 1.5646 | 1.3706 | 1.4261 | 1.3359 | 1.3344 | 1.1737 | 1.2697 | 1.3613 | 1.3342 | 1.7411 | 1.0651 | 1.1575 | 1.2047 | 1.3007 | 1.3544 | 1.2257 | 1.2382 | 1.1624 | 1.7390 | 1.3078 | 0.9419 | 1.2981 |
| aspartate | 0.4521 | NA | NA | 0.6878 | NA | NA | 1.8701 | 1.0942 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.9553 | 0.9744 | NA | NA | NA | NA | NA | NA | 1.0991 | 1.5500 | 0.6652 | NA | NA | NA | NA | NA | NA | NA | NA | 1.7724 | 1.7951 | NA | NA | NA | NA | NA | NA | 0.7280 | NA | NA | NA | NA | NA |
| aspartate-13C6-15N4 | 0.9050 | 0.5968 | 0.4480 | 1.2744 | 1.3849 | 1.2740 | 1.2991 | 1.2219 | 0.7980 | 0.7537 | 0.7563 | 0.6610 | 0.6921 | 0.7455 | 0.7661 | 0.6848 | 0.6885 | 0.6238 | 0.7005 | 0.8718 | 0.8207 | 0.6790 | 0.5281 | 0.7039 | 0.7046 | 0.6858 | 0.7311 | 0.7348 | 0.8712 | 1.2153 | 1.3003 | 1.2223 | 1.2759 | 1.2705 | 1.2850 | 1.3102 | 1.2108 | 1.1964 | 1.2400 | 1.2744 | 1.2532 | 1.2988 | 1.4057 | 1.2758 | 1.2989 | 1.2821 | 1.2373 | 1.2559 | 1.3979 | 1.2741 | 1.1222 | 1.2898 | 1.3226 | 1.3037 |
| ATP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| CDP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| CoA-Ellmans_unc | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| CTP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| GDP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| glutamate | 1.0566 | 0.6487 | 0.7702 | 1.4184 | 0.3078 | 0.4848 | 3.8652 | 0.9654 | 0.8881 | 1.0516 | 1.1744 | 0.9680 | 0.5585 | 0.6818 | 0.9412 | 0.4685 | 0.4258 | 0.9777 | 0.5248 | 1.7379 | 1.8548 | 0.6670 | 1.3003 | 0.7638 | 1.1285 | 0.9565 | 0.9220 | 0.8922 | 0.9426 | 3.0524 | 0.1850 | 2.3936 | 2.0529 | 0.2879 | 0.4387 | 0.6540 | 0.3183 | 0.7430 | 0.7788 | 0.3032 | 0.1927 | 1.6530 | 1.4282 | 1.9558 | 1.4242 | 0.5055 | 0.4682 | 0.5377 | 1.5462 | 0.9676 | 0.2620 | 0.2904 | 0.7981 | 0.3446 |
| glutamate-13C5,15N | 0.9065 | 0.5892 | 0.4780 | 1.2042 | 1.3910 | 1.2314 | 1.2229 | 1.1970 | 0.7488 | 0.7151 | 0.6801 | 0.6872 | 0.7260 | 0.7001 | 0.7817 | 0.6804 | 0.7376 | 0.5943 | 0.6589 | 0.9201 | 0.8264 | 0.6684 | 0.5713 | 0.6905 | 0.6992 | 0.7007 | 0.6987 | 0.6616 | 0.8502 | 1.2628 | 1.3361 | 1.2723 | 1.2391 | 1.2507 | 1.3811 | 1.2974 | 1.2313 | 1.2273 | 1.2318 | 1.3355 | 1.2768 | 1.3957 | 1.3696 | 1.3107 | 1.3286 | 1.3045 | 1.2487 | 1.1890 | 1.3947 | 1.2711 | 1.1691 | 1.3065 | 1.2704 | 1.2836 |
| glutamine | 0.6477 | 0.9325 | 1.0112 | 1.1883 | 0.2985 | 0.9952 | 1.0656 | 1.1462 | 1.3514 | 1.2760 | 1.4557 | 1.3088 | 0.9156 | 1.4035 | 1.6256 | 1.1860 | 1.1604 | 1.3300 | 1.2918 | 1.3520 | 1.3431 | 1.1289 | 1.1161 | 1.6667 | 1.0963 | 1.3001 | 1.2573 | 1.2142 | 1.3650 | 0.9399 | 0.2827 | 0.9449 | 0.8368 | 1.0907 | 1.1716 | 1.1752 | 1.1135 | 1.2118 | 1.0259 | 1.2980 | 0.2908 | 0.9624 | 1.5250 | 1.3756 | 1.4195 | 1.4735 | 1.4251 | 1.3438 | 1.2034 | 1.2044 | 0.2605 | 1.2779 | 1.4718 | 1.3481 |
| GMP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| GSH | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| GSH-13C2_15N | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| GSH_13C2-15N-Ellmans | 0.9605 | 0.0293 | 0.0864 | 0.9794 | 0.7012 | 0.6434 | 0.7027 | 2.2017 | 0.0764 | 0.0932 | 0.1283 | 0.0567 | 0.0766 | 0.0568 | 0.1069 | 0.1139 | 0.0519 | 0.0770 | 0.0608 | 0.0950 | 0.1212 | 0.0263 | 0.1250 | 0.0233 | 0.0418 | 0.0619 | 0.0611 | 0.0119 | 0.1304 | 1.1307 | 1.8178 | 1.8321 | 1.8276 | 1.7983 | 2.0652 | 1.7759 | 1.8268 | 1.9319 | 1.7489 | 1.9098 | 1.7036 | 2.1721 | 1.9760 | 2.0001 | 1.8135 | 1.9583 | 1.8627 | 2.1280 | 1.9479 | 1.8026 | 1.7322 | 1.8935 | 1.9561 | 2.0794 |
| GSH_Ellmans | 0.4971 | 0.0823 | 0.0794 | NA | NA | NA | NA | 0.1789 | NA | 0.2962 | 0.7846 | 0.9655 | 0.6183 | 0.6341 | 4.1394 | NA | 0.0980 | 0.2277 | NA | 0.3319 | 1.4048 | NA | 0.8924 | NA | NA | NA | 0.2206 | 0.4947 | 1.7187 | 10.8078 | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.3460 | NA | NA | 0.1716 | 0.1835 | NA | 0.1749 | NA | NA | NA | NA | NA | 0.3713 | NA | 2.2972 |
| GSSG | 0.2381 | NA | NA | NA | NA | NA | NA | 0.0380 | 0.3145 | 0.9752 | 1.0493 | 2.0659 | 1.8305 | 2.3035 | 0.3191 | NA | NA | NA | NA | NA | 1.9840 | NA | NA | NA | NA | NA | 0.1283 | NA | NA | 2.2997 | NA | NA | 0.1257 | NA | 0.0964 | 0.3182 | 0.1293 | NA | 0.0988 | 0.1874 | NA | NA | 2.9790 | 2.7882 | 2.2624 | NA | NA | NA | NA | NA | NA | 0.6029 | NA | 5.9603 |
| GTP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| histidine | 0.9332 | 0.6772 | 0.7843 | 1.1566 | 0.0987 | 0.7584 | 0.9006 | 1.0476 | 0.7977 | 0.8869 | 1.7074 | 1.1382 | 0.6398 | 1.3775 | 1.4977 | 0.8844 | 0.8671 | 0.7510 | 0.8989 | 1.0587 | 0.4520 | 0.6137 | 0.9947 | 1.3081 | 0.8925 | 1.0719 | 1.2734 | 1.0953 | 1.3742 | 0.4130 | 0.1076 | 1.1130 | 0.9177 | 1.4095 | 1.0526 | 1.1975 | 0.9121 | 0.8408 | 1.1116 | 1.3530 | 0.1225 | 0.6978 | 1.7955 | 1.3070 | 1.6623 | 1.2572 | 1.5042 | 1.1499 | 1.1190 | 1.1350 | 0.1010 | 1.2466 | 2.1637 | 1.3732 |
| histidine-13C6-15N3 | 0.9129 | 0.5920 | 0.4880 | 1.4440 | 1.2622 | 1.2340 | 1.0111 | 1.0762 | 0.8439 | 0.8515 | 0.6997 | 0.6957 | 0.6654 | 0.5893 | 0.4380 | 0.6914 | 0.6656 | 0.6962 | 0.7401 | 0.7812 | 0.8328 | 0.8240 | 0.5204 | 0.5437 | 0.7717 | 0.6462 | 0.6932 | 0.7274 | 0.7012 | 0.8114 | 1.5264 | 1.2476 | 1.2461 | 1.4095 | 1.5412 | 1.2137 | 1.3371 | 1.2416 | 1.2128 | 1.5592 | 1.3318 | 1.1839 | 1.2518 | 1.3524 | 1.2947 | 1.3010 | 1.3314 | 1.2739 | 1.3470 | 1.2911 | 1.3619 | 1.4465 | 0.9821 | 1.5713 |
| isoleucine | 0.8512 | 0.5526 | 0.8746 | 0.8076 | 0.1327 | 0.6731 | 0.7426 | 1.2676 | 0.8865 | 0.8687 | 1.3084 | 0.6760 | 0.2938 | 0.5394 | 1.1157 | 1.0185 | 0.7843 | 0.8298 | 1.0383 | 1.1936 | 0.9584 | 1.2505 | 1.5806 | 1.6729 | 0.7304 | 0.8092 | 1.1139 | 0.9235 | 1.5992 | 0.6435 | NA | 1.1648 | 0.7676 | 1.0014 | 1.1417 | 0.9017 | 0.7110 | 1.3317 | 0.9638 | 1.0979 | NA | 1.3680 | 1.7686 | 1.4386 | 1.0894 | 1.9330 | 0.9181 | 1.0487 | 0.9635 | 0.9942 | 0.0936 | 0.6005 | 4.5533 | 0.6437 |
| Isoleucine-13C6-15N | 0.9549 | 0.5542 | 0.3639 | 1.1886 | 1.7229 | 1.0883 | 0.9293 | 1.0744 | 0.6232 | 0.6807 | 0.5920 | 0.6424 | 0.8189 | 0.5849 | 0.4819 | 0.7098 | 0.6531 | 0.6682 | 0.5686 | 0.7828 | 0.7040 | 0.6039 | 0.5789 | 0.5421 | 0.6055 | 0.5784 | 0.6615 | 0.5199 | 0.7105 | 1.1472 | 0.5541 | 1.5091 | 1.5088 | 1.5000 | 1.6488 | 1.3201 | 1.6412 | 1.3420 | 1.4873 | 1.6051 | 0.5721 | 1.3497 | 1.2134 | 1.3035 | 1.3456 | 1.2897 | 1.3709 | 1.2921 | 1.4563 | 1.3839 | 1.5923 | 1.5879 | 0.9946 | 1.4730 |
| lactic_acid | 0.8304 | 0.6659 | 0.6770 | 1.3498 | 0.0852 | 0.7867 | 0.7991 | 0.9631 | 1.8580 | 1.1917 | 1.2891 | 0.8834 | 0.5350 | 1.4187 | 1.9309 | 0.9836 | 0.9541 | 1.4326 | 0.9968 | 1.1894 | 2.1792 | 1.0276 | 0.7921 | 1.9116 | 1.1885 | 1.2324 | 0.9427 | 1.0117 | 0.9516 | 2.0595 | 0.0773 | 0.9045 | 0.6780 | 0.9310 | 0.9586 | 0.8228 | 0.7009 | 1.0003 | 0.8568 | 0.8868 | 0.0808 | 0.6725 | 1.3605 | 1.0628 | 0.9963 | 1.0184 | 0.9029 | 0.8137 | 1.3110 | 1.4052 | 0.0786 | 1.4668 | 2.3843 | 1.2254 |
| leucine | 0.8780 | 0.7333 | 1.0268 | 0.9180 | 0.1865 | 0.8207 | 1.2536 | 1.3830 | 0.8417 | 1.0668 | 1.4328 | 0.7190 | 0.4601 | 1.2025 | 1.0231 | 0.8122 | 0.8144 | 0.8690 | 2.4200 | 0.9322 | 1.0807 | 0.7500 | 1.2984 | 1.8731 | 0.9624 | 0.9905 | 0.9020 | 0.8946 | 1.1698 | 0.6388 | 0.2218 | 1.1638 | 0.7503 | 0.9371 | 1.1139 | 0.8702 | 0.8963 | 1.0320 | 1.1982 | 1.3269 | 0.2349 | 0.9651 | 1.5698 | 1.1554 | 1.0195 | 1.7057 | 0.8142 | 0.8099 | 0.9814 | 1.0663 | 0.1746 | 0.7703 | 3.6846 | 1.0145 |
| leucine-13C6-15N | 0.8896 | 0.5805 | 0.4792 | 1.1901 | 2.1668 | 1.1391 | 1.0769 | 1.0323 | 0.7103 | 0.7079 | 0.6590 | 0.6175 | 0.7802 | 0.5970 | 0.5936 | 0.6220 | 0.5947 | 0.5930 | 0.5927 | 0.6805 | 0.6935 | 0.6599 | 0.4285 | 0.5626 | 0.5419 | 0.5940 | 0.5778 | 0.5587 | 0.5852 | 1.1657 | 2.3527 | 1.4819 | 1.1843 | 1.3477 | 1.4873 | 1.2329 | 1.4043 | 1.0840 | 1.2101 | 1.2873 | 2.3995 | 1.1345 | 1.2012 | 1.2372 | 0.9997 | 1.1620 | 1.1635 | 1.1759 | 1.2123 | 1.2220 | 2.1356 | 1.2895 | 1.1243 | 1.4562 |
| lysine | 0.6841 | 0.9526 | 0.8553 | 1.1637 | 0.1963 | 0.9385 | 1.0297 | 1.1350 | 1.1758 | 1.2507 | 1.1779 | 1.2738 | 0.6784 | 1.2485 | 1.6904 | 0.8339 | 0.8389 | 0.8355 | 0.9245 | 1.4696 | 1.5191 | 1.0539 | 1.3744 | 1.5796 | 1.2320 | 1.5025 | 1.4321 | 1.0635 | 1.4753 | 2.3905 | 0.0665 | 1.1001 | 0.8728 | 1.0999 | 0.9405 | 0.9993 | 1.2772 | 1.0963 | 0.9503 | 1.4228 | 0.0791 | 0.8957 | 1.3610 | 1.3111 | 1.3433 | 1.2711 | 1.0357 | 0.9915 | 1.3124 | 1.3155 | 0.1422 | 1.2805 | 2.5762 | 1.2327 |
| lysine-13C6-15N2 | 0.9186 | 0.5805 | 0.4078 | 1.2737 | 1.7706 | 1.2612 | 1.0889 | 0.9859 | 0.7680 | 0.7247 | 0.6368 | 0.6405 | 0.6798 | 0.6412 | 0.5989 | 0.6800 | 0.6060 | 0.6464 | 0.5623 | 0.8538 | 0.7505 | 0.6739 | 0.5308 | 0.5411 | 0.6706 | 0.6306 | 0.6385 | 0.6286 | 0.7201 | 1.1075 | 0.9850 | 1.3299 | 1.4115 | 1.4005 | 1.4879 | 1.2731 | 1.2851 | 1.2369 | 1.3168 | 1.4490 | 1.0628 | 1.4831 | 1.3817 | 1.4359 | 1.4052 | 1.4823 | 1.3414 | 1.3758 | 1.4014 | 1.3656 | 1.2364 | 1.3308 | 1.1241 | 1.4003 |
| methionine | 0.7124 | 0.3652 | 0.5881 | 0.8429 | 0.0673 | 0.6856 | 0.6673 | 1.6662 | 1.2637 | 0.8126 | 1.2072 | 0.7743 | 0.5750 | 1.1394 | 1.9504 | 1.0574 | 0.8086 | 0.7551 | 1.0867 | 0.8713 | 0.9598 | 1.0493 | 0.9810 | 2.0341 | 0.4503 | 0.5653 | 0.9220 | 0.5083 | 1.8353 | 1.7367 | NA | 0.7580 | 0.2377 | 0.9089 | 1.4207 | 0.6612 | 1.3741 | 0.8723 | 0.8547 | 1.7916 | NA | 0.9561 | 1.8742 | 1.6310 | 1.0928 | 2.3163 | 1.2066 | 0.8808 | 1.1340 | 1.3329 | 0.0572 | 1.0060 | 4.6619 | 0.6338 |
| methionine-13C5-15N | 0.9799 | 0.5744 | 0.4444 | 1.1079 | 1.7564 | 1.0105 | 0.8668 | 1.0160 | 0.5670 | 0.5725 | 0.6010 | 0.5868 | 0.7486 | 0.6178 | 0.6112 | 0.6775 | 0.5808 | 0.5632 | 0.5506 | 0.7357 | 0.6695 | 0.5897 | 0.6359 | 0.5029 | 0.5147 | 0.5824 | 0.6460 | 0.5016 | 0.6685 | 1.0546 | 0.2698 | 1.6005 | 1.2835 | 1.5215 | 1.8913 | 1.2997 | 1.7369 | 1.5287 | 1.4083 | 1.7542 | 0.2848 | 1.4040 | 1.5093 | 1.3888 | 1.3201 | 1.4240 | 1.4469 | 1.2993 | 1.4617 | 1.4765 | 1.5803 | 1.5069 | 1.2076 | 1.1625 |
| NAD+ | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| NADH | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| NADP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| NADPH | 0.8047 | 2.3003 | 1.3764 | 0.5879 | NA | 0.5566 | NA | 1.4859 | 1.1412 | 0.6478 | 3.2935 | NA | 0.5738 | 0.6152 | 0.4913 | 0.5611 | NA | 0.8033 | 0.9028 | 1.0094 | 1.1870 | 1.1498 | 0.8972 | 0.6139 | NA | 1.0620 | NA | 0.6483 | NA | NA | NA | 1.4542 | 1.3817 | NA | NA | NA | NA | 0.8859 | 1.5561 | 0.4581 | 0.4652 | 1.1287 | 0.7785 | 0.7008 | 2.3609 | NA | NA | 1.0380 | NA | 0.9691 | NA | 1.0659 | NA | NA |
| niacinamide | 0.8164 | 0.2460 | 0.2203 | 0.3604 | 0.2316 | 0.4245 | 0.6836 | 0.6019 | 0.6511 | 0.6459 | 0.6382 | 0.4982 | 0.3736 | 0.5151 | 0.3670 | 0.6823 | 0.5226 | 0.4464 | 1.2328 | 1.1999 | 0.7352 | 0.5742 | 1.9022 | 0.5291 | 0.7631 | 0.3847 | 5.0671 | 1.8649 | 0.7342 | 19.2491 | 0.3335 | 0.4841 | 0.8046 | 0.5213 | 0.3658 | 0.5725 | 0.5972 | 0.3913 | 2.1452 | 0.3082 | 0.2821 | 0.9859 | 0.5158 | 0.7340 | 0.6123 | 0.6271 | 0.6107 | 0.5058 | 0.3730 | 0.3444 | 0.1985 | 0.2798 | 0.6754 | 0.3231 |
| Nicotinic Acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| palmitate | 0.4693 | 1.6931 | 1.0742 | 0.6310 | 0.0622 | 1.2136 | 2.4090 | 2.6376 | 0.7652 | 0.6576 | 1.3445 | 1.0038 | 0.6211 | 0.8871 | 2.0397 | 0.8589 | 0.7079 | 0.4712 | 0.6472 | 1.0398 | 1.2227 | 0.4971 | 0.9496 | 1.4482 | 0.4477 | 0.7155 | 0.8790 | 1.1110 | 0.7412 | NA | 9.8480 | 0.5901 | 0.3626 | 0.5067 | 0.2521 | 0.3815 | 0.2296 | 0.4462 | 0.6492 | 0.6109 | 9.2946 | 0.3784 | 1.4069 | 1.7260 | 0.8804 | 1.0012 | 0.4830 | 0.7277 | 0.6794 | 0.8699 | NA | 0.3592 | 1.4128 | 0.2725 |
| phenylalanine | 0.6971 | 0.5407 | 0.7201 | 1.0391 | 0.1010 | 0.6787 | 1.0464 | 1.3471 | 1.1211 | 0.6357 | 2.4724 | 0.8680 | 0.4024 | 0.9403 | 1.3794 | 0.7688 | 0.6233 | 1.7744 | 0.8286 | 1.0780 | 1.2805 | 0.7661 | 0.8191 | 1.6144 | 0.9737 | 0.8901 | 0.9858 | 1.0931 | 1.2226 | 0.4264 | 0.0974 | 0.7399 | 0.6241 | 1.1133 | 0.5947 | 0.6726 | 0.7067 | 0.6987 | 0.6510 | 0.9103 | 0.1100 | 0.6889 | 2.7315 | 2.3672 | 1.1693 | 1.3863 | 1.1745 | 1.1578 | 1.1309 | 1.1864 | 0.0951 | 1.9499 | 4.2718 | 3.7866 |
| phenylalanine-13C9-15N | 0.9098 | 0.6624 | 0.5719 | 1.2311 | 1.5546 | 1.1847 | 1.0758 | 1.0935 | 0.6753 | 0.6859 | 0.6725 | 0.7289 | 0.7531 | 0.6745 | 0.6963 | 0.7134 | 0.6572 | 0.6564 | 0.6580 | 0.8497 | 0.7839 | 0.6507 | 0.5348 | 0.6195 | 0.6481 | 0.6824 | 0.6867 | 0.6075 | 0.7399 | 1.3045 | 1.4535 | 1.3543 | 1.2599 | 1.3578 | 1.3848 | 1.2742 | 1.4095 | 1.2923 | 1.3386 | 1.3762 | 1.4851 | 1.3758 | 1.1996 | 1.2881 | 1.3099 | 1.2875 | 1.2411 | 1.2450 | 1.3271 | 1.3262 | 1.3607 | 1.2236 | 1.0135 | 1.2060 |
| proline | 0.5800 | 0.2633 | 0.3782 | 0.3183 | 0.0788 | 0.2424 | 0.7255 | 0.9239 | 0.4748 | 0.3640 | 4.0003 | 1.0227 | 0.5554 | 1.8139 | 6.4832 | 0.3312 | 0.2786 | 0.3106 | 0.2697 | 0.6431 | 1.6026 | 0.8034 | 1.1802 | 0.7007 | 0.5489 | 0.9414 | 1.0779 | 0.7719 | 1.9613 | 0.9001 | 0.1588 | 0.3055 | 0.1926 | 0.2854 | 0.4120 | 0.2964 | 0.2572 | 0.7376 | 0.2677 | 0.4962 | 0.1773 | 1.6934 | 4.5307 | 2.4808 | 2.3473 | 1.6300 | 0.9188 | 0.6035 | 0.4644 | 0.4155 | 0.0566 | 0.1763 | 10.6366 | 0.2125 |
| proline-13C5-15N | 0.9356 | 0.6328 | 0.4981 | 1.1989 | 1.4375 | 1.1389 | 1.0722 | 1.1323 | 0.7279 | 0.7242 | 0.6731 | 0.7034 | 0.7848 | 0.7049 | 0.6309 | 0.7766 | 0.7040 | 0.6846 | 0.6275 | 0.8006 | 0.8937 | 0.6770 | 0.6263 | 0.6727 | 0.6929 | 0.6716 | 0.7353 | 0.6429 | 0.7688 | 1.2195 | 0.9244 | 1.3757 | 1.2694 | 1.3719 | 1.4990 | 1.2965 | 1.4038 | 1.2891 | 1.3316 | 1.4748 | 0.8981 | 1.2642 | 1.2283 | 1.2826 | 1.3341 | 1.3229 | 1.2837 | 1.2564 | 1.3870 | 1.2938 | 1.2487 | 1.4354 | 0.9409 | 1.3643 |
| serine | 0.8624 | 0.7189 | 0.5401 | 0.9429 | 0.6655 | 0.8718 | 0.8146 | 0.9512 | 1.5069 | 1.3500 | 1.4141 | 1.2207 | 1.0022 | 1.3629 | 1.6039 | 1.0055 | 0.9540 | 0.8256 | 0.8231 | 1.2001 | 1.4702 | 1.0454 | 1.5027 | 1.0560 | 0.9715 | 0.9682 | 0.8711 | 0.8529 | 1.2888 | 1.3192 | 0.6515 | 0.9204 | 0.9234 | 0.9848 | 0.9498 | 1.0398 | 0.7891 | 0.8417 | 0.9263 | 1.0793 | 0.7446 | 1.5729 | 1.3981 | 1.3069 | 1.3050 | 1.0114 | 1.0485 | 0.9207 | 0.8219 | 0.9158 | 0.4938 | 1.0279 | 0.9314 | 1.4761 |
| serine-13C3-15N | 0.9887 | 0.5742 | 0.3333 | 1.2629 | 2.0474 | 1.2587 | 1.0561 | 1.0821 | 0.6643 | 0.6200 | 0.5594 | 0.5442 | 0.7061 | 0.6643 | 0.4105 | 0.6936 | 0.3915 | 0.5717 | 0.5968 | 0.8409 | 0.9524 | 0.6494 | 0.5440 | 0.5579 | 0.6380 | 0.5804 | 0.6969 | 0.6261 | 0.6953 | 1.1396 | 1.6110 | 1.3873 | 1.4008 | 1.3395 | 1.2545 | 1.2302 | 1.3629 | 1.2890 | 1.1252 | 1.2237 | 1.6853 | 1.6024 | 1.0905 | 1.1589 | 1.1446 | 1.1596 | 1.3055 | 1.2701 | 1.2767 | 1.2725 | 1.4200 | 1.1233 | 1.1581 | 1.3201 |
| taurine | 0.6864 | 0.4804 | 0.5239 | 0.5494 | 0.0805 | 0.6901 | 0.6865 | 0.8107 | 0.9668 | 1.2082 | 1.9316 | 1.1523 | 0.7039 | 1.4773 | 2.8910 | 0.7055 | 0.8397 | 0.3564 | 1.0723 | 0.7871 | 1.1644 | 0.5513 | 0.8321 | 1.0407 | 0.7932 | 0.8604 | 0.7331 | 0.5331 | 1.1457 | 12.6839 | 0.0806 | 0.9631 | 0.7305 | 0.8530 | 0.5230 | 0.8430 | 0.9614 | 0.5990 | 0.7783 | 1.1645 | 0.0800 | 0.8432 | 1.9910 | 1.5330 | 1.5203 | 0.9097 | 0.8883 | 0.8664 | 0.6022 | 0.6354 | 0.0634 | 0.8634 | 2.0480 | 1.3073 |
| threonine | 0.8881 | 0.9723 | 0.9062 | 1.4644 | 0.2095 | 0.6151 | 1.1208 | 1.0471 | 1.1347 | 1.4694 | 1.2078 | 1.0720 | 0.3534 | 0.9323 | 1.0079 | 1.1195 | 1.1611 | 0.7243 | 1.0502 | 1.3630 | 0.9214 | 1.1330 | 1.2105 | 1.5044 | 1.2434 | 1.1274 | 1.1903 | 1.2973 | 1.6259 | 0.4371 | 0.4445 | 0.7972 | 1.3867 | 0.8621 | 1.3842 | 1.3461 | 1.0377 | 0.5327 | 1.4021 | 1.1483 | 0.2180 | 1.0783 | 0.9116 | 0.8861 | 0.8463 | 1.3478 | 1.4185 | 0.8656 | 1.2700 | 1.1968 | 0.2047 | 0.5608 | 1.9649 | 1.0583 |
| threonine-13C4-15N | 0.8917 | 0.6889 | 0.5069 | 1.1868 | 2.0889 | 1.3024 | 1.0510 | 1.0270 | 0.6179 | 0.6028 | 0.7141 | 0.7391 | 0.8379 | 0.6256 | 0.4999 | 0.7240 | 0.6341 | 0.6777 | 0.6343 | 0.7130 | 0.6795 | 0.7500 | 0.5485 | 0.4571 | 0.7483 | 0.5824 | 0.7148 | 0.6761 | 0.7117 | 0.9703 | 1.9794 | 1.2441 | 1.3166 | 1.4114 | 1.4989 | 1.1444 | 1.3649 | 1.1520 | 1.1917 | 1.2325 | 2.0086 | 1.4320 | 1.1633 | 1.2586 | 1.2895 | 1.1208 | 1.3277 | 1.3653 | 1.2236 | 1.0002 | 1.9371 | 1.1854 | 0.8811 | 1.2926 |
| tryptophan | 0.8026 | 0.5554 | 0.5604 | 0.8228 | 0.1293 | 0.5813 | 1.0690 | 0.8686 | 0.7454 | 0.6366 | 1.5611 | 1.3163 | 0.9280 | 1.5768 | 1.6145 | 0.6512 | 0.7241 | 0.7978 | 0.8677 | 1.3604 | 1.1135 | 0.8591 | 1.3040 | 1.2116 | 0.6490 | 0.8224 | 0.8619 | 0.6228 | 1.2053 | 0.5399 | NA | 1.0309 | 0.9251 | 0.9026 | 0.9522 | 1.0187 | 1.0045 | 0.9459 | 1.1505 | 1.0092 | NA | 0.8117 | 2.0265 | 2.1060 | 1.7698 | 0.7322 | 0.7231 | 0.8066 | 0.9991 | 1.0042 | 0.0938 | 1.6599 | 3.2526 | 2.6779 |
| tyrosine | 0.6918 | 0.6910 | 0.7923 | 1.0909 | 0.1247 | 0.4961 | 1.0165 | 1.1559 | 0.9831 | 0.7102 | 1.5465 | 1.6702 | 0.7157 | 1.6498 | 2.2204 | 0.8767 | 0.8529 | 0.9027 | 0.8562 | 1.0444 | 1.5550 | 1.3994 | 1.1129 | 1.6877 | 0.7509 | 0.9062 | 1.0705 | 0.7931 | 1.2864 | 0.5487 | 0.1211 | 0.5410 | 0.6463 | 0.9071 | 0.9679 | 0.9841 | 1.4053 | 0.9228 | 0.5698 | 1.3896 | 0.1271 | 0.6830 | 1.8744 | 1.7921 | 1.5326 | 1.4673 | 1.2195 | 0.9192 | 1.2979 | 1.3099 | 0.1177 | 1.5690 | 3.1697 | 2.1985 |
| tyrosine-13C9-15N | 0.9310 | 0.6052 | 0.4805 | 1.1538 | 1.8252 | 1.0807 | 1.0872 | 1.1396 | 0.6648 | 0.6717 | 0.5567 | 0.6110 | 0.7449 | 0.6690 | 0.6509 | 0.7397 | 0.6448 | 0.6079 | 0.4863 | 0.7372 | 0.8077 | 0.6375 | 0.5620 | 0.6040 | 0.5904 | 0.6313 | 0.6763 | 0.5377 | 0.6981 | 1.1330 | 1.4537 | 1.4321 | 1.1879 | 1.4500 | 1.5726 | 1.3161 | 1.4760 | 1.3210 | 1.3883 | 1.5249 | 1.3945 | 1.1383 | 1.1513 | 1.2120 | 1.3059 | 1.2418 | 1.3003 | 1.2464 | 1.3417 | 1.3327 | 1.6011 | 1.4265 | 0.9582 | 1.2962 |
| UMP | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| valine | 0.9064 | 0.9077 | 0.7300 | 0.7888 | 0.2808 | 0.6790 | 1.1501 | 0.8641 | 0.7852 | 0.6565 | 1.1532 | 0.6986 | 0.7030 | 0.8016 | 1.5066 | 1.0271 | 1.3873 | 0.6880 | 1.1161 | 1.0036 | 1.1361 | 0.5699 | 1.3962 | 1.6753 | 0.8962 | 0.8399 | 0.9702 | 0.6795 | 1.6107 | 0.3098 | NA | 1.0605 | 0.7791 | 0.7682 | 0.8694 | 0.8856 | 1.1604 | 1.5949 | 0.6773 | 1.1495 | NA | 1.5785 | 1.5838 | 1.2434 | 1.3825 | 1.6469 | 1.1494 | 1.0583 | 0.9676 | 1.0072 | 0.2473 | 1.0184 | 2.8501 | 0.7141 |
| valine-13C5-15N | 0.9377 | 0.5883 | 0.4581 | 1.2075 | 1.7498 | 1.0394 | 0.9691 | 1.0105 | 0.5771 | 0.5984 | 0.5431 | 0.5805 | 0.7442 | 0.5851 | 0.5431 | 0.8253 | 0.8074 | 0.5469 | 0.5323 | 0.7196 | 0.8341 | 0.6166 | 0.5582 | 0.5516 | 0.5887 | 0.5728 | 0.6281 | 0.4979 | 0.7704 | 1.1913 | 0.3729 | 1.5790 | 1.2869 | 1.4545 | 1.6804 | 1.3422 | 1.6261 | 1.4135 | 1.3222 | 1.7012 | 0.3775 | 1.7709 | 1.2936 | 1.2752 | 1.3863 | 1.3187 | 1.3470 | 1.3051 | 1.5874 | 1.4941 | 1.5721 | 1.6877 | 0.9209 | 1.4460 |
Factors:
| F1 | Factor:- |
| F2 | Factor:L10-1 |
| F3 | Factor:L10-2 |
| F4 | Factor:L1-1 |
| F5 | Factor:L1-2 |
| F6 | Factor:L1-3 |
| F7 | Factor:L1-4 |
| F8 | Factor:L1-5 |
| F9 | Factor:L2-1 |
| F10 | Factor:L2-2 |
| F11 | Factor:L3-1 |
| F12 | Factor:L3-2 |
| F13 | Factor:L3-3 |
| F14 | Factor:L3-4 |
| F15 | Factor:L3-5 |
| F16 | Factor:L4-1 |
| F17 | Factor:L4-2 |
| F18 | Factor:L5-1 |
| F19 | Factor:L5-2 |
| F20 | Factor:L6-1 |
| F21 | Factor:L6-2 |
| F22 | Factor:L6-3 |
| F23 | Factor:L7-1 |
| F24 | Factor:L7-2 |
| F25 | Factor:L8-1 |
| F26 | Factor:L8-2 |
| F27 | Factor:L9-1 |
| F28 | Factor:L9-2 |
| F29 | Factor:L9-3 |
| F30 | Factor:mouse control |
| F31 | Factor:N25 |
| F32 | Factor:N55 |
| F33 | Factor:N58 |
| F34 | Factor:N61 |
| F35 | Factor:N66 |
| F36 | Factor:N75 |
| F37 | Factor:N88 |
| F38 | Factor:N9 |
| F39 | Factor:N91 |
| F40 | Factor:N93 |
| F41 | Factor:N95 |
| F42 | Factor:NJ3 |
| F43 | Factor:patient12_1 12/5/02 |
| F44 | Factor:patient12_2 1/16/03 |
| F45 | Factor:patient12_3 5/23/03 |
| F46 | Factor:patient13_1 12/29/11 |
| F47 | Factor:patient13_2 4/28/14 |
| F48 | Factor:patient13_3 7/16/14 |
| F49 | Factor:patient2_1 6/10/07 |
| F50 | Factor:patient2_2 6/11/07 |
| F51 | Factor:patient2_3 4/22/08 |
| F52 | Factor:patient4_1 8/31/10 |
| F53 | Factor:patient4_2 6/11/11 |
| F54 | Factor:patient4_3 7/9/11 |
