Data for (Study ST002011)

(Analysis AN003277)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
2_3-Diphosphoglyceric acid 1.1853 0.8412
2-dehydro-D-gluconate 1.3003 0.7748
2-Hydroxy-2-methylbutanedioic acid 1.3011 0.7742
3-phosphoglycerate 1.1087 0.9185
3-phospho-serine 1.1650 0.8585
4-aminobutyrate 1.2711 0.7966
4-phosphopantetheine 1.0071 0.9915
4-phosphopantothenate 1.2801 0.7899
4-Pyridoxic acid 1.3392 0.7456
5-phosphoribosyl-1-pyrophosphate 1.0493 0.9578
6-phospho-D-gluconate 1.2483 0.8137
acetyl-aspartate 1.2892 0.7831
acetyl-CoA 1.2289 0.8038
Acetyllysine 1.1802 0.8455
ADP-D-glucose 1.0342 0.9590
a-ketoglutarate 1.2484 0.8137
alanine/sarcosine 1.1953 0.8535
arginine 1.0410 0.9693
asparagine 1.2660 0.8005
aspartate 1.2938 0.7796
aspartate (standard) 0.9261 1.0554
Asp-Leu-His (DLH) 0.9994 1.0007
Asp-Leu-Ser (DLS) 1.2874 0.7845
Atovaquone NA 1.0000
biotin 1.1879 0.8591
CDP 1.1335 0.8665
CDP-choline 1.0254 0.9695
CDP-ethanolamine 1.1987 0.8297
chlorpropamide 0.9918 1.0062
citrate/isocitrate 1.2615 0.8039
CMP 1.0952 0.8857
coenzyme A 1.1912 0.8361
CTP 1.1865 0.8402
cyclic-AMP 1.2391 0.8207
cytidine 1.1464 0.8902
dAMP 1.0790 0.9210
dATP 1.1583 0.8643
dCDP 1.0928 0.9072
dCMP 1.1093 0.8907
dCTP 1.0553 0.9447
Decanoyl-CoA 1.1592 0.8636
deoxyuridine 1.2640 0.8020
dGDP/ADP 1.2545 0.8091
D-gluconate 1.2760 0.7930
D-glucosamine-1/6-phosphate 1.0392 0.9608
dGMP/AMP 1.2314 0.8265
dGTP/ATP 1.2517 0.8112
dihydroorotate 0.7697 1.1727
dihydroxy-acetone-phosphate 1.0696 0.9478
DL-Pipecolic Acid 1.2045 0.8466
D-sedoheptulose-1/7-phosphate 1.2604 0.8047
dTDP 1.0312 0.9626
dTMP 1.3274 0.7544
dTTP 1.2888 0.7834
FAD 1.0123 0.9852
FMN 1.0279 0.9665
folate 1.1503 0.8711
fructose-1-6-bisphosphate 1.0843 0.9278
fructose-6-phosphate 1.2273 0.8295
fumarate 1.2431 0.8177
GDP 1.2418 0.8186
glucono-lactone 1.3521 0.7359
glucose-1-phosphate 1.2273 0.8295
glutamate 1.2724 0.7957
glutamine 1.2711 0.7967
glutathione 1.2835 0.7873
glutathione disulfide 1.2362 0.8229
glycerate 1.0440 0.9670
GMP 1.2511 0.8117
GTP 1.1483 0.8729
guanine 1.1662 0.8753
guanosine 1.2203 0.8348
Hexose 1.3887 0.7085
histidine 1.2531 0.8102
His-Val-Asp-Asp (HVDD) 1.1549 0.8838
hydroxyproline/Aminolevulinate 1.2614 0.8040
hypoxanthine 1.2714 0.7964
IMP 1.2445 0.8166
indole 0.9994 1.0007
inosine 1.2617 0.8037
isoleucine 1.2588 0.8059
lactate 1.1577 0.8817
L-arginino-succinate 1.1058 0.8731
Leu-Asp (LD) 1.3212 0.7591
leucine 1.2430 0.8178
lysine 1.3080 0.7690
malate 1.2402 0.8198
maleic acid 1.2275 0.8294
methionine 1.2513 0.8115
N-acetyl-glucosamine-1/6-phosphate 0.9564 1.0523
N-acetyl-glutamate 1.3071 0.7696
N-acetyl-glutamine 1.2210 0.8342
N-Acetyl-L-alanine 1.2547 0.8090
N-acetyl-L-ornithine 1.2861 0.7854
NAD+ 1.2799 0.7901
NADH 0.9753 1.0296
NADP+ 1.2092 0.8207
NADPH 1.0812 0.9188
N-carbamoyl-L-aspartate 1.0672 0.9496
nicotinamide mononucleotide 1.2969 0.7773
nicotinate 1.0455 0.9545
Octulose 8/1P 1.2769 0.7924
Octulose Bisphosphate 0.9830 1.0204
orotate 1.3791 0.7157
orotidine-5^-phosphate 1.0295 0.9646
pantothenate 1.2707 0.7970
Phenol Red 1.2631 0.8027
phenylalanine 1.2404 0.8197
phosphoenolpyruvate 1.1782 0.8664
Pro-Asp (PD) 1.2281 0.8289
Pro-Glu-Glu-Lys (PEEK) 1.0263 0.9684
Pro-Glu-Glu (PEE) 1.2666 0.8000
Pro-Glu (PE) 1.2360 0.8230
proline 1.2420 0.8185
Pro-Val-Asn-Phe (PVNF) 0.9949 1.0061
pyridoxine 1.2236 0.8323
Pyroglutamic acid 1.1657 0.8758
pyruvate 1.1288 0.9034
ribose 1.2451 0.8162
Ribose-5-phosphate 1.2446 0.8166
ribose-phosphate 1.2009 0.8494
ribulose-5-phosphate 1.2323 0.8258
S-adenosyl-L-homocysteine 1.0795 0.9205
Sedoheptulose bisphosphate 1.1265 0.8916
Ser-Asp (SD) 1.2228 0.8329
Ser-Ile-Asp (SID) 1.2907 0.7820
serine 1.2834 0.7875
sn-glycerol-3-phosphate 1.1695 0.8729
succinate/Methylmalonic acid 1.2048 0.8464
succinyl-CoA/methylmalonyl-CoA 0.9731 1.0322
thiamine 1.2761 0.7929
Thiamine pyrophosphate 0.9843 1.0188
threonine/homoserine 1.2792 0.7906
thymidine 1.1925 0.8556
tryptophan 1.2438 0.8172
tyrosine 1.2571 0.8071
UDP 1.3168 0.7624
UDP-D-glucose 1.1052 0.8948
UDP-D-glucuronate 1.0171 0.9795
UDP-N-acetyl-glucosamine 1.1136 0.8864
UMP 1.3415 0.7439
uridine 1.3491 0.7381
UTP 1.1917 0.8357
Val-Asp (VD) 1.2653 0.8011
valine 1.2337 0.8247
xanthosine 1.0687 0.9313
xanthosine-5-phosphate 1.2773 0.7623
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Factors:

F1Concentration:10X IC50 | Treatment time:2.5 hours | Parasite Stage:MACS purified Troph
F2Concentration:N/A | Treatment time:N/A | Parasite Stage:MACS purified Troph
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