Data for (Study ST002038)
(Analysis AN003315)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
4-Acetamidobutanoate | 0.8730 | 0.9278 | 1.1467 | 0.9869 | 1.0894 | 1.0657 | 1.1651 | 0.9852 | 0.8707 | 0.6177 | 1.2147 | 1.0390 |
5-6-Dihydrothymine | 0.8249 | 0.5079 | 1.1066 | 0.5109 | 0.7070 | 0.8041 | 1.7744 | 1.2252 | 1.1384 | 0.6606 | 1.8219 | 0.9323 |
5-Hydroxyindoleacetate | 0.7728 | 0.8249 | 0.8639 | 0.8097 | 1.0007 | 1.6902 | 1.0050 | 0.7969 | 1.3478 | 0.8310 | 1.0334 | 1.1164 |
5-Hydroxyisourate | 1.2811 | 1.1271 | 0.8791 | 0.9103 | 1.0772 | 1.1024 | 1.4275 | 0.6044 | 0.8045 | 0.9546 | 0.7899 | 1.0036 |
(5-L-Glutamyl)-L-glutamine | 1.3208 | 1.6896 | 0.8088 | 0.9832 | 0.9914 | 1.1141 | 1.2203 | 0.6784 | 0.8249 | 0.7754 | 0.7253 | 0.7912 |
6-Hydroxykynurenic acid | 1.2099 | 0.5959 | 0.6534 | 0.4885 | 1.2816 | 1.2619 | 1.4447 | 0.6861 | 1.9009 | 0.5356 | 1.3485 | 0.7163 |
6-Phospho-D-gluconate | 0.7396 | 0.8850 | 1.0670 | 0.9274 | 0.7424 | 1.2071 | 0.7378 | 1.2991 | 1.1425 | 1.0721 | 1.1762 | 1.0404 |
acetyl-carnitine (acyl-C2) | 0.8625 | 1.0676 | 0.9991 | 1.1939 | 0.8842 | 0.7880 | 0.7301 | 1.4736 | 0.8845 | 1.3274 | 0.8681 | 0.8723 |
Acetylcholine | 0.9006 | 0.6514 | 0.8847 | 0.7152 | 0.6734 | 0.7159 | 1.4607 | 1.0083 | 1.1770 | 1.0642 | 1.4238 | 1.4505 |
acyl-C18:2 (Linoleoyl-CoA) | 0.7691 | 0.9430 | 0.8853 | 0.9653 | 1.0446 | 1.1418 | 1.0449 | 1.0555 | 0.9370 | 1.1322 | 1.0697 | 0.9985 |
acyl-C18:2-OH | 0.6822 | 0.7010 | 0.9499 | 0.9398 | 0.7739 | 0.8125 | 0.8803 | 1.0370 | 1.2501 | 1.3826 | 1.2733 | 1.4592 |
acyl-C20:4 | 1.1547 | 1.0114 | 0.7780 | 1.3334 | 1.1350 | 0.9460 | 0.7870 | 1.0049 | 0.9686 | 1.2917 | 0.7702 | 0.7659 |
acyl-C4-DC | 0.8329 | 0.7617 | 1.0105 | 0.7165 | 0.8647 | 0.9502 | 0.9617 | 1.1531 | 1.0000 | 1.0461 | 1.6246 | 1.0975 |
acyl-C4-OH | 0.7664 | 0.9344 | 0.8597 | 1.0051 | 0.7302 | 0.9938 | 0.8664 | 1.0186 | 1.4739 | 1.1236 | 0.9488 | 1.4673 |
acyl-C5-OH | 0.9015 | 0.6825 | 1.0015 | 0.9545 | 0.9034 | 0.9052 | 0.9645 | 1.1346 | 1.2967 | 1.0627 | 1.2086 | 1.0545 |
acyl-C6-DC | 0.9054 | 1.2565 | 1.3090 | 0.6806 | 0.5640 | 1.1052 | 0.9072 | 1.2471 | 1.0952 | 0.8809 | 1.0644 | 1.0043 |
Adenine | 0.6757 | 1.0855 | 1.3130 | 1.0483 | 1.0036 | 0.8586 | 0.7470 | 1.4244 | 0.5965 | 1.1307 | 1.1792 | 0.8212 |
Adenosine | 0.5283 | 1.2335 | 1.3769 | 1.2284 | 1.2999 | 0.7235 | 0.5120 | 1.6701 | 0.4477 | 0.7942 | 1.3181 | 0.6959 |
Allantoate | 1.1839 | 0.9205 | 0.7732 | 0.7891 | 0.9972 | 0.9167 | 1.5263 | 0.6197 | 1.1184 | 0.7073 | 1.1956 | 1.3448 |
Argininosuccinate | 1.0722 | 0.7980 | 0.7736 | 0.8458 | 1.1773 | 1.2942 | 1.3597 | 0.5948 | 0.9706 | 0.8016 | 1.0666 | 1.2997 |
butanoyl-l-carnitine (acyl-C4) | 0.8965 | 0.9193 | 0.9552 | 1.2457 | 0.8912 | 0.8003 | 0.8922 | 1.1209 | 1.1782 | 1.2613 | 0.7839 | 1.1137 |
Carnosine | 1.1352 | 0.5612 | 0.5822 | 0.9787 | 1.5013 | 2.0784 | 1.0871 | 0.5124 | 0.9690 | 0.6097 | 0.9067 | 1.0898 |
Choline | 0.9160 | 1.1437 | 1.0177 | 0.9253 | 1.0446 | 0.8575 | 1.1024 | 1.1031 | 0.9165 | 0.8635 | 1.0693 | 1.0296 |
Creatine | 1.1551 | 1.1126 | 0.9990 | 0.9307 | 0.9332 | 0.9300 | 1.1410 | 1.0027 | 0.8761 | 0.8898 | 1.0770 | 0.9101 |
Creatinine | 1.0653 | 0.9825 | 0.9377 | 0.8981 | 0.9596 | 0.9289 | 1.1243 | 1.0714 | 1.0004 | 0.9117 | 1.0972 | 1.0288 |
Cys-Gly | 0.8021 | 0.9933 | 1.1149 | 1.1353 | 1.0337 | 1.0184 | 0.8904 | 1.1646 | 1.0950 | 0.9532 | 0.8273 | 0.9886 |
Cytidine | 1.0986 | 0.9228 | 1.0223 | 1.1412 | 1.0474 | 1.7660 | 0.9096 | 0.6943 | 1.2824 | 0.5824 | 0.8048 | 0.7308 |
Cytosine | 1.4024 | 1.0454 | 0.9273 | 1.0742 | 1.0364 | 1.3985 | 1.0459 | 0.7009 | 0.9857 | 0.6772 | 0.8288 | 0.8431 |
dCMP | 0.6766 | 0.3648 | 0.6497 | 1.2091 | 0.4246 | 1.1769 | 1.6420 | 1.1093 | 1.6831 | 1.5498 | 0.9234 | 0.6841 |
Dimethylglycine | 1.0503 | 1.1555 | 1.0133 | 0.8817 | 0.9799 | 0.9824 | 1.0309 | 1.0664 | 0.9717 | 1.0266 | 1.1767 | 0.5738 |
Dopamine | 1.1165 | 0.9200 | 0.5887 | 0.8235 | 1.1547 | 1.2521 | 1.6153 | 0.6221 | 0.8241 | 0.7515 | 1.2039 | 1.1156 |
Ectoine | 0.6834 | 0.3987 | 1.1121 | 0.2389 | 0.6252 | 0.6532 | 2.2513 | 1.3423 | 1.0089 | 0.8257 | 1.8718 | 0.9879 |
gamma-Glutamyl-gamma-aminobutyrate | 1.1401 | 0.8111 | 0.6991 | 0.8075 | 1.0396 | 1.3520 | 1.1625 | 0.6559 | 1.5715 | 0.5869 | 0.9314 | 1.4459 |
gamma-Glutamyl-Se-methylselenocysteine | 1.0930 | 0.8956 | 0.7826 | 0.8041 | 0.9365 | 0.9381 | 1.3302 | 0.6206 | 1.3375 | 0.8352 | 1.3025 | 1.2393 |
gamma-L-Glutamyl-D-alanine | 1.1647 | 1.1651 | 0.8754 | 0.8288 | 0.9881 | 1.4521 | 0.9610 | 0.8864 | 1.1704 | 0.8654 | 0.7916 | 0.8563 |
gamma-L-Glutamylputrescine | 1.2487 | 0.4258 | 0.5671 | 1.1715 | 1.4430 | 2.4025 | 1.1289 | 0.4636 | 0.9977 | 0.4683 | 0.8565 | 0.7824 |
glycine | 1.0812 | 1.0048 | 0.9958 | 0.8819 | 1.0471 | 1.0513 | 1.2792 | 0.8179 | 1.0039 | 0.8591 | 0.9704 | 1.0103 |
g-Oxalo-crotonate | 1.2932 | 1.4571 | 0.8205 | 1.2273 | 0.8808 | 0.6932 | 1.2027 | 0.8744 | 1.4621 | 0.7092 | 0.7605 | 0.6397 |
Guanidinoacetate | 0.9261 | 1.3022 | 0.6493 | 0.5249 | 1.0581 | 1.3417 | 1.4379 | 0.8772 | 0.9180 | 0.5912 | 0.8600 | 1.6213 |
Guanine | 1.1622 | 0.9350 | 0.6743 | 0.9232 | 1.0891 | 1.0444 | 1.4418 | 0.8168 | 0.9261 | 0.7710 | 1.0540 | 1.1842 |
Hexadecenoyl-carnitine (acyl-C16:1) | 0.8818 | 0.8549 | 0.9473 | 1.2900 | 1.0967 | 1.0619 | 1.0495 | 0.9203 | 0.9983 | 1.1624 | 0.8305 | 0.8825 |
hexanoyl-L-carnitine (acyl-C6) | 0.6968 | 0.9062 | 0.9923 | 1.0644 | 0.8021 | 0.7499 | 0.8544 | 1.5961 | 0.9894 | 1.4444 | 0.9661 | 0.9200 |
Hypotaurine | 1.5176 | 1.2203 | 0.8607 | 1.0181 | 1.3321 | 0.6272 | 0.9196 | 1.0207 | 1.0862 | 0.7175 | 0.8956 | 0.7521 |
Hypoxanthine | 1.2217 | 1.4149 | 0.9300 | 1.0987 | 0.9024 | 0.5876 | 0.9262 | 1.1636 | 1.4980 | 0.8260 | 0.8535 | 0.5962 |
Indole | 1.0140 | 0.8498 | 0.6740 | 0.8087 | 1.2298 | 1.5424 | 1.4097 | 0.6410 | 0.8448 | 0.7238 | 1.2119 | 1.0239 |
Indole-3-acetaldehyde | 0.7414 | 1.0887 | 0.9547 | 1.0454 | 1.0680 | 0.6760 | 1.0181 | 1.2518 | 0.7922 | 1.2762 | 1.2129 | 0.7911 |
Indole-3-acetate | 0.9456 | 1.1696 | 0.9838 | 0.9587 | 1.0063 | 0.9635 | 0.8919 | 1.1685 | 1.0345 | 0.8548 | 1.1088 | 0.9013 |
Indoxyl | 1.0715 | 0.6545 | 0.7589 | 0.7232 | 1.1438 | 1.0954 | 1.5608 | 1.1124 | 0.9577 | 0.8649 | 1.3649 | 0.6045 |
Inositol 1-2-3-5-6-pentakisphosphate | 1.1808 | 1.1929 | 0.9715 | 0.8692 | 1.0488 | 1.0286 | 1.1744 | 0.7197 | 0.7875 | 0.6887 | 1.1079 | 1.2416 |
L-alanine | 1.0876 | 0.9076 | 0.8874 | 0.8514 | 1.1025 | 1.2052 | 1.2816 | 0.7201 | 0.9262 | 0.8589 | 1.0561 | 1.1257 |
L-arginine | 1.1345 | 0.6703 | 0.4745 | 1.0095 | 1.1890 | 2.0009 | 1.4853 | 0.5415 | 0.8433 | 0.6587 | 0.9993 | 0.9523 |
L-asparagine | 1.1199 | 1.0259 | 0.7966 | 0.8571 | 1.1137 | 1.0936 | 1.6066 | 0.6433 | 0.7811 | 0.7615 | 1.0833 | 1.0921 |
L-aspartate | 1.0614 | 0.8888 | 0.7959 | 0.8693 | 1.1067 | 1.1942 | 1.3822 | 0.6778 | 0.8851 | 0.8898 | 1.0771 | 1.1859 |
L-Carnitine | 1.0474 | 0.8920 | 0.9426 | 0.9812 | 0.8140 | 0.7873 | 1.1521 | 1.0802 | 1.0092 | 1.1028 | 1.1733 | 1.0248 |
L-Citrulline | 0.9531 | 0.8668 | 0.9890 | 0.8720 | 1.1348 | 1.0311 | 0.9683 | 1.0390 | 0.9629 | 0.8736 | 1.1746 | 1.1593 |
L-cysteine | 1.2814 | 0.9767 | 0.8636 | 0.9986 | 0.6558 | 1.0064 | 1.5387 | 0.9976 | 1.3226 | 0.6644 | 0.9336 | 0.7815 |
L-cystine | 1.2738 | 0.9354 | 0.5815 | 0.5793 | 1.3502 | 1.4584 | 1.6576 | 0.5240 | 0.9500 | 0.4807 | 0.8377 | 1.4518 |
L-glutamate | 1.1012 | 0.9886 | 0.9164 | 0.8159 | 1.0286 | 1.0934 | 1.3913 | 0.7956 | 0.9849 | 0.8594 | 1.0343 | 0.9842 |
L-glutamine | 1.2513 | 1.0947 | 0.7965 | 0.9521 | 1.1122 | 1.1607 | 1.4104 | 0.5840 | 0.8370 | 0.9127 | 0.8615 | 0.9928 |
L-histidine | 1.1299 | 0.9361 | 0.7061 | 0.8444 | 1.2421 | 1.2533 | 1.6242 | 0.6433 | 0.8003 | 0.7188 | 1.0438 | 1.0222 |
L-Homocysteine | 0.8679 | 1.3091 | 0.9758 | 1.3705 | 0.9670 | 0.7327 | 0.7416 | 0.9237 | 1.3183 | 1.1665 | 1.0260 | 0.5807 |
L-leucine/isoleucine | 1.1229 | 0.9059 | 0.7579 | 0.8903 | 1.1352 | 1.2616 | 1.3804 | 0.6774 | 0.9265 | 0.8037 | 1.0987 | 1.0310 |
L-lysine | 1.1375 | 0.8192 | 0.6189 | 0.7815 | 1.1753 | 1.4328 | 1.6034 | 0.5994 | 0.8556 | 0.7283 | 1.1779 | 1.0517 |
L-methionine | 1.1369 | 0.9020 | 0.7825 | 0.9030 | 1.0871 | 1.1062 | 1.3962 | 0.7212 | 0.9464 | 0.8289 | 1.1092 | 1.0872 |
L-Methionine S-oxide | 0.8691 | 0.6862 | 0.8284 | 0.4740 | 0.9114 | 1.0838 | 1.8078 | 0.7393 | 0.9452 | 0.9273 | 1.1789 | 1.6719 |
L-octanoylcarnitine (acyl-C8) | 0.6367 | 0.8012 | 0.8772 | 1.3890 | 0.8512 | 0.7791 | 0.8442 | 1.4511 | 1.0519 | 1.4652 | 0.8218 | 1.0522 |
L-Palmitoylcarnitine (acyl-C16) | 1.0821 | 0.9874 | 0.7716 | 1.1445 | 1.0384 | 0.8281 | 1.1131 | 1.0927 | 0.9543 | 1.0304 | 1.0653 | 0.8537 |
L-phenylalanine | 1.1402 | 0.9189 | 0.7109 | 0.9730 | 1.0418 | 1.2673 | 1.3960 | 0.6462 | 0.9704 | 0.7859 | 1.0400 | 1.1293 |
L-proline | 1.0979 | 1.0603 | 0.8517 | 0.6820 | 1.1536 | 1.1223 | 1.2734 | 0.8107 | 0.8432 | 0.7775 | 1.1789 | 1.1465 |
L-serine | 1.1442 | 0.9866 | 0.7817 | 0.9082 | 1.0494 | 1.0933 | 1.6070 | 0.6440 | 0.8245 | 0.7997 | 1.0510 | 1.0943 |
L-threonine | 1.1204 | 0.9784 | 0.7408 | 0.8089 | 1.1085 | 1.1925 | 1.5887 | 0.6829 | 0.8635 | 0.7833 | 1.0855 | 1.0240 |
L-tryptophan | 1.0858 | 0.9406 | 0.7069 | 0.8244 | 1.1644 | 1.4771 | 1.4026 | 0.6520 | 0.8578 | 0.7186 | 1.1304 | 1.0136 |
L-tyrosine | 1.1627 | 0.8708 | 0.7650 | 0.9238 | 1.1183 | 1.1352 | 1.3081 | 0.7096 | 0.9732 | 0.8315 | 1.0690 | 1.1592 |
L-valine | 1.1589 | 0.8979 | 0.7777 | 0.9202 | 1.0275 | 1.0590 | 1.3682 | 0.8649 | 0.8863 | 0.9148 | 1.1245 | 0.9717 |
N-Acetylornithine | 1.2961 | 0.6830 | 0.7087 | 0.9340 | 1.2312 | 1.6126 | 0.9816 | 0.5685 | 1.2337 | 0.6366 | 0.8757 | 1.3565 |
NAD+ | 0.4819 | 0.4791 | 1.6167 | 0.9600 | 1.1894 | 1.0462 | 0.5606 | 0.8475 | 1.3834 | 1.8589 | 0.6551 | 0.9971 |
N-formyl kynurenine | 0.5293 | 0.2677 | 1.3846 | 1.1160 | 0.4614 | 1.4416 | 0.8035 | 0.4932 | 0.8942 | 1.0988 | 1.1854 | 2.6289 |
Nicotinamide | 0.9935 | 1.0954 | 0.9623 | 0.9804 | 0.9408 | 0.9061 | 0.8824 | 1.2249 | 1.1094 | 0.8889 | 1.1182 | 0.8995 |
octenoyl-l-carnitine (acyl-C8:1) | 0.7520 | 0.8370 | 1.0164 | 0.8219 | 0.6174 | 0.7037 | 1.1871 | 1.7427 | 0.8502 | 1.2114 | 1.1024 | 1.1599 |
O-Decenoyl-L-carnitine (acyl-C10:1) | 0.5430 | 0.8501 | 0.9209 | 1.0381 | 0.8173 | 1.2079 | 0.8171 | 1.2339 | 0.7472 | 1.4751 | 0.8184 | 1.6006 |
O-dodecanoyl-carnitine (acyl-C12) | 0.6851 | 0.7601 | 0.8696 | 1.1412 | 0.9983 | 0.9506 | 1.1472 | 1.3693 | 0.8614 | 1.1500 | 1.0043 | 1.0441 |
O-dodecenoyl-carnitine (acyl-C12:1) | 1.1043 | 0.6199 | 0.7939 | 1.3651 | 0.9747 | 1.2186 | 0.8512 | 0.8889 | 0.9007 | 1.4409 | 0.8456 | 0.9703 |
O-octadecenoyl-L-carnitine (acyl-C18:1) | 0.9223 | 1.0472 | 1.0293 | 1.1965 | 0.9288 | 1.0526 | 0.9661 | 0.9334 | 0.9944 | 1.0146 | 1.0189 | 0.8685 |
Ornithine | 1.2070 | 0.8828 | 0.6206 | 0.6652 | 1.0695 | 1.0908 | 1.8815 | 0.5308 | 0.9553 | 0.6591 | 1.2898 | 1.1734 |
O-tetradecanoyl-L-carnitine (acyl-C14) | 0.5880 | 0.8063 | 0.8180 | 1.0649 | 0.9095 | 0.7559 | 1.3865 | 1.3475 | 0.9055 | 1.1987 | 1.1592 | 1.0514 |
Phosphoserine | 1.0501 | 1.0372 | 0.9456 | 0.9558 | 0.9795 | 0.9276 | 1.1006 | 0.8993 | 1.0248 | 1.0036 | 1.0673 | 1.0168 |
Picolinic acid | 0.6214 | 0.7909 | 1.3346 | 1.0569 | 1.1317 | 0.8567 | 0.8203 | 1.3314 | 0.9493 | 1.2815 | 0.8328 | 0.9780 |
propionyl-carnitine (acyl-C3) | 1.1660 | 0.8770 | 0.7276 | 1.1208 | 1.0494 | 0.8870 | 0.8777 | 1.1943 | 0.9381 | 1.0253 | 1.0346 | 1.1123 |
Putrescine | 1.0411 | 1.0964 | 0.7099 | 1.1802 | 0.7031 | 0.6902 | 1.1375 | 1.2489 | 1.1951 | 1.0471 | 1.0507 | 0.9235 |
S-Adenosyl-L-homocysteine | 0.8172 | 1.3146 | 0.8827 | 0.8718 | 0.7010 | 0.7286 | 1.1369 | 1.1589 | 1.5153 | 1.1151 | 0.8515 | 1.0119 |
S-Adenosyl-L-methionine | 0.7471 | 0.9378 | 1.1367 | 1.2516 | 0.8842 | 0.9936 | 0.9565 | 0.7902 | 0.8435 | 0.8802 | 1.0322 | 1.6440 |
Serotonin | 0.7377 | 1.0369 | 0.9834 | 1.0279 | 1.1116 | 0.6923 | 0.8676 | 1.3863 | 0.8256 | 1.2431 | 1.2208 | 0.7899 |
Spermidine | 1.0513 | 0.8345 | 0.6819 | 0.9139 | 0.9869 | 2.1119 | 1.1794 | 0.6186 | 1.1825 | 0.6695 | 0.8720 | 0.9176 |
Sphingosine | 1.1565 | 1.0001 | 0.8454 | 0.8237 | 0.9634 | 1.1679 | 1.8321 | 0.5841 | 1.3632 | 0.6290 | 1.0351 | 0.5902 |
Tetradecenoyl Carnitine (acyl-C14:1) | 0.6992 | 0.8786 | 0.8567 | 1.2549 | 1.0251 | 0.9305 | 1.1605 | 0.9505 | 0.7784 | 1.3435 | 0.9143 | 1.2044 |
Xanthine | 1.1141 | 0.9910 | 0.7685 | 0.9145 | 0.8189 | 0.8681 | 1.4418 | 0.8197 | 1.4903 | 0.8363 | 1.1239 | 0.8888 |
Factors:
F1 | Treatment:IV iron | Radiation Dose:Gy10 |
F2 | Treatment:IV iron | Radiation Dose:Gy11 |
F3 | Treatment:IV iron | Radiation Dose:Gy7 |
F4 | Treatment:IV iron | Radiation Dose:Gy8 |
F5 | Treatment:IV iron | Radiation Dose:Gy9 |
F6 | Treatment:IV iron | Radiation Dose:no irradiated |
F7 | Treatment:Saline | Radiation Dose:Gy10 |
F8 | Treatment:Saline | Radiation Dose:Gy11 |
F9 | Treatment:Saline | Radiation Dose:Gy7 |
F10 | Treatment:Saline | Radiation Dose:Gy8 |
F11 | Treatment:Saline | Radiation Dose:Gy9 |
F12 | Treatment:Saline | Radiation Dose:no irradiated |