Data for (Study ST002039)
(Analysis AN003317)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
5-6-Dihydrouracil | 0.8148 | 0.9635 | 1.1103 | 0.7841 | 1.2562 | 1.1591 | 0.9601 | 0.8716 | 1.0587 | 0.9289 | 1.0489 | 1.0695 |
5-Guanidino-2-oxopentanoate | 1.1187 | 0.5780 | 1.2188 | 0.9966 | 1.0773 | 1.1089 | 1.0580 | 0.8733 | 1.0133 | 1.1834 | 0.6278 | 1.1858 |
5-Hydroxyindoleacetate | 1.4247 | 1.6366 | 0.8306 | 0.5791 | 0.8336 | 0.7354 | 1.1844 | 0.7783 | 1.1844 | 0.8356 | 0.7917 | 1.2781 |
5-Hydroxyisourate | 1.2873 | 1.0665 | 0.9194 | 1.0011 | 1.1187 | 0.9443 | 0.9742 | 0.9487 | 0.8959 | 0.9599 | 0.9152 | 0.9348 |
5^-Phosphoribosyl-N-formylglycinamide | 0.9691 | 1.0988 | 1.1862 | 1.1410 | 0.9974 | 0.9229 | 0.8464 | 0.5906 | 1.7555 | 0.6810 | 0.8005 | 1.2020 |
6-Hydroxykynurenic acid | 1.0061 | 0.9411 | 0.9505 | 0.8766 | 1.3054 | 0.9730 | 0.7274 | 0.4869 | 1.1366 | 0.6464 | 1.3839 | 1.7416 |
6-Phospho-D-gluconate | 1.0480 | 0.9588 | 0.9455 | 1.0577 | 1.0843 | 1.0094 | 0.8293 | 0.8819 | 1.0566 | 1.0267 | 0.9622 | 1.1888 |
acetyl-carnitine (acyl-C2) | 0.9104 | 0.9517 | 1.0677 | 0.9742 | 1.2543 | 1.3088 | 0.7739 | 0.8614 | 1.0575 | 1.0471 | 0.9540 | 0.8130 |
Acetylcholine | 1.1185 | 0.9768 | 0.6988 | 1.1733 | 0.6985 | 0.6041 | 1.6484 | 1.4589 | 0.7063 | 0.8173 | 0.9120 | 1.1605 |
acyl-C18:2 (Linoleoyl-CoA) | 1.2856 | 1.2231 | 1.0822 | 1.0580 | 1.2184 | 1.0020 | 0.6952 | 0.7105 | 0.9899 | 0.9825 | 0.7204 | 1.0376 |
acyl-C20:4 | 1.3980 | 0.9416 | 0.8229 | 1.4547 | 1.2236 | 0.6834 | 0.8458 | 0.9110 | 0.7250 | 0.9107 | 0.7265 | 1.3773 |
acyl-C4-DC | 1.0251 | 0.6842 | 1.2167 | 0.5797 | 1.2852 | 1.3985 | 0.6474 | 0.5635 | 1.2761 | 0.9773 | 1.3450 | 1.0706 |
acyl-C4-OH | 0.9762 | 1.0733 | 0.8758 | 0.9503 | 1.4008 | 0.8920 | 0.9850 | 1.0209 | 1.0662 | 0.9544 | 0.8511 | 0.9591 |
acyl-C5-OH | 0.9922 | 1.0471 | 1.1152 | 0.9289 | 1.1931 | 1.2399 | 0.9020 | 0.8416 | 1.0610 | 0.9530 | 0.9191 | 0.7739 |
Adenosine | 0.8545 | 1.2247 | 0.6742 | 1.9635 | 0.5642 | 0.6262 | 1.1411 | 1.3146 | 0.9151 | 1.1138 | 0.6534 | 0.9222 |
ADP-D-ribose | 0.5526 | 0.7794 | 1.3094 | 0.6338 | 0.7584 | 1.5745 | 0.7683 | 0.7097 | 1.6415 | 1.6043 | 1.0705 | 0.6576 |
Allantoate | 1.0109 | 0.9900 | 0.9707 | 1.0908 | 0.9422 | 0.9140 | 1.0615 | 0.8871 | 1.0289 | 1.0282 | 0.9625 | 1.1488 |
butanoyl-l-carnitine (acyl-C4) | 0.9376 | 0.9239 | 1.0772 | 0.9722 | 1.0239 | 0.9660 | 1.0704 | 1.2490 | 0.8916 | 0.9106 | 0.8502 | 1.1320 |
Carnosine | 2.2273 | 0.5086 | 1.1327 | 0.4591 | 0.4376 | 0.9008 | 0.5090 | 0.3568 | 1.1635 | 2.2376 | 0.4308 | 1.8361 |
Choline | 0.9480 | 0.9271 | 1.0790 | 0.8204 | 1.2825 | 1.1545 | 0.8591 | 0.9366 | 1.1572 | 0.7564 | 1.1537 | 0.9462 |
Creatinine | 0.9521 | 0.9990 | 1.0170 | 0.9775 | 1.1691 | 1.0960 | 0.9228 | 0.8795 | 0.9942 | 0.9771 | 1.0184 | 0.9952 |
Cys-Gly | 0.9634 | 0.9518 | 1.0022 | 0.9176 | 0.9409 | 0.9357 | 1.0764 | 1.1523 | 1.0402 | 1.0645 | 0.9306 | 1.0404 |
Cytidine | 1.0065 | 0.9649 | 0.8037 | 1.1861 | 0.9322 | 0.7289 | 0.9882 | 1.3504 | 0.8412 | 0.9197 | 1.0498 | 1.2459 |
Cytosine | 0.9606 | 1.0189 | 0.7701 | 1.2430 | 0.9545 | 0.8651 | 1.1095 | 1.3671 | 0.7025 | 0.9405 | 0.8893 | 1.1492 |
Dimethylglycine | 1.0833 | 0.9553 | 0.9213 | 0.7335 | 0.9895 | 1.0585 | 0.9451 | 0.9397 | 1.0716 | 1.0702 | 1.0048 | 1.3019 |
Flavin mononucleotide | 0.8069 | 1.1899 | 0.9829 | 0.8727 | 1.2912 | 1.0551 | 0.9280 | 0.9105 | 0.9221 | 0.9496 | 1.0431 | 1.0407 |
gamma-Glutamyl-gamma-aminobutyrate | 0.7963 | 1.0239 | 1.4438 | 0.7705 | 1.2888 | 1.5110 | 0.7027 | 0.6648 | 1.2168 | 0.9215 | 0.8226 | 0.8510 |
gamma-L-Glutamyl-L-cysteine | 0.9894 | 0.8372 | 1.0957 | 0.8827 | 1.1927 | 1.4007 | 0.7315 | 0.6074 | 1.2040 | 0.9799 | 0.8645 | 1.3189 |
gamma-L-Glutamylputrescine | 0.9325 | 1.3648 | 1.4767 | 0.6532 | 0.9657 | 1.3270 | 0.6110 | 0.5592 | 1.4851 | 1.0037 | 0.9646 | 0.6920 |
Glutathione | 0.9038 | 0.9742 | 0.9768 | 0.9855 | 0.9406 | 0.9855 | 1.0486 | 1.1326 | 0.9525 | 1.1107 | 0.9380 | 1.0523 |
glycine | 1.1889 | 1.0842 | 1.2575 | 0.6498 | 0.9632 | 1.0336 | 0.9092 | 0.7271 | 1.4312 | 1.0113 | 1.0805 | 0.6872 |
Guanidinoacetate | 0.8731 | 1.1821 | 1.0731 | 0.7650 | 1.0173 | 1.1055 | 1.0139 | 0.7926 | 1.1403 | 0.9152 | 1.0964 | 1.0669 |
Guanine | 0.7781 | 0.9255 | 1.1194 | 0.9262 | 1.3385 | 1.2897 | 0.7284 | 0.8441 | 1.0944 | 1.0357 | 0.9901 | 0.9361 |
Guanosine | 0.9255 | 0.9713 | 0.9822 | 0.8815 | 1.1753 | 1.1053 | 0.8779 | 0.9208 | 1.1140 | 1.0087 | 1.0021 | 1.0727 |
Hexadecenoyl-carnitine (acyl-C16:1) | 1.4534 | 1.4681 | 1.2000 | 0.8390 | 0.9943 | 0.9168 | 0.8719 | 0.7166 | 0.9515 | 0.8644 | 0.8414 | 0.8411 |
hexanoyl-L-carnitine (acyl-C6) | 0.9579 | 1.0904 | 1.0142 | 1.0101 | 0.8971 | 0.8785 | 1.1073 | 1.3413 | 0.6930 | 0.8283 | 0.9340 | 1.2331 |
Hypoxanthine | 0.9913 | 0.9908 | 0.9720 | 0.7325 | 1.3278 | 1.1070 | 0.7682 | 0.7398 | 1.1728 | 0.9636 | 1.1339 | 1.1688 |
Indole | 1.3138 | 1.0689 | 0.8752 | 1.0044 | 1.3318 | 0.8716 | 0.9479 | 0.9193 | 0.9650 | 0.8022 | 0.9015 | 0.9893 |
Indole-3-acetaldehyde | 1.4065 | 1.4059 | 0.8160 | 0.8214 | 0.4906 | 0.4568 | 1.4695 | 1.5468 | 1.0114 | 0.9387 | 0.6630 | 0.9694 |
Indole-3-acetate | 1.0265 | 0.8925 | 0.9487 | 0.9007 | 1.2575 | 1.0327 | 0.8655 | 0.7368 | 1.1927 | 0.9515 | 1.1104 | 1.1538 |
Indolepyruvate | 1.0014 | 0.9659 | 1.0841 | 0.8166 | 1.3230 | 1.0133 | 0.8662 | 0.5727 | 1.4106 | 0.8690 | 1.1418 | 1.0220 |
Indoxyl | 1.2158 | 0.6969 | 0.7148 | 0.8482 | 1.2567 | 0.9779 | 1.5445 | 1.0799 | 0.9507 | 0.8318 | 1.1513 | 0.6523 |
Inosine | 1.0243 | 1.0616 | 0.9433 | 0.7821 | 1.1194 | 1.0093 | 0.8513 | 0.9034 | 1.2122 | 1.1070 | 1.0161 | 1.0156 |
L-Adrenaline | 1.0301 | 1.0088 | 1.0734 | 0.7451 | 1.3006 | 1.3208 | 0.8172 | 0.8509 | 1.0710 | 0.9496 | 0.8804 | 0.9581 |
L-alanine | 1.0162 | 0.9539 | 0.9309 | 0.9249 | 0.9986 | 0.9586 | 1.1850 | 1.0446 | 0.9399 | 0.9338 | 1.0963 | 1.0068 |
L-arginine | 1.0568 | 1.0369 | 0.9533 | 0.7706 | 1.0104 | 0.9884 | 0.9237 | 1.0480 | 1.2049 | 1.0422 | 0.9507 | 1.0689 |
L-asparagine | 1.2670 | 1.0742 | 0.8505 | 0.9645 | 0.7719 | 0.8446 | 1.2435 | 0.9464 | 1.0955 | 0.9352 | 0.9924 | 1.0419 |
L-aspartate | 1.1207 | 1.0306 | 1.0158 | 0.9012 | 0.9669 | 0.9910 | 0.9521 | 0.7985 | 1.1520 | 0.9994 | 1.0192 | 1.1037 |
L-Carnitine | 0.8486 | 0.9927 | 1.1745 | 0.8787 | 1.2186 | 1.2762 | 0.7688 | 0.8536 | 1.0770 | 1.0910 | 0.9673 | 0.8356 |
L-Citrulline | 0.8987 | 0.8147 | 1.0961 | 0.8507 | 1.2290 | 1.2846 | 0.8989 | 0.8720 | 1.0865 | 0.9405 | 0.9903 | 1.0691 |
L-cysteine | 1.2526 | 0.8911 | 1.2468 | 0.7634 | 1.0196 | 1.0076 | 0.9195 | 0.9165 | 1.1048 | 0.9775 | 0.9972 | 0.9055 |
L-glutamate | 0.9359 | 1.0561 | 0.9266 | 1.1502 | 0.9399 | 0.8659 | 1.1397 | 1.0488 | 0.9351 | 0.9242 | 1.0342 | 1.0382 |
L-glutamine | 1.2324 | 1.0590 | 0.9383 | 1.0985 | 0.9939 | 0.9318 | 0.9652 | 1.0666 | 0.8610 | 0.9716 | 0.9329 | 0.9012 |
L-histidine | 1.4283 | 0.8339 | 1.1441 | 0.7753 | 0.9268 | 1.0093 | 0.7583 | 0.7458 | 1.2421 | 1.2785 | 0.8133 | 1.1157 |
L-leucine/isoleucine | 1.0758 | 0.9811 | 0.9082 | 0.8740 | 1.1523 | 0.9609 | 1.0553 | 0.9388 | 1.0800 | 0.9025 | 0.9732 | 1.1424 |
L-lysine | 0.9980 | 1.0242 | 0.9860 | 0.9652 | 1.0005 | 1.0052 | 0.9696 | 0.9231 | 1.1073 | 1.0384 | 0.9264 | 1.0969 |
L-methionine | 1.0975 | 0.7210 | 0.9738 | 0.7380 | 0.9902 | 0.9536 | 1.1445 | 1.1652 | 1.0093 | 0.8843 | 1.1327 | 1.2396 |
L-octanoylcarnitine (acyl-C8) | 1.0384 | 0.9878 | 0.9695 | 1.0207 | 1.0028 | 1.0550 | 0.9646 | 1.0101 | 0.9084 | 0.9038 | 1.0471 | 1.0919 |
L-Palmitoylcarnitine (acyl-C16) | 1.1620 | 1.2793 | 1.1440 | 0.8159 | 1.1568 | 0.9433 | 0.8079 | 0.7694 | 1.1351 | 0.8863 | 0.8202 | 1.1333 |
L-phenylalanine | 1.3329 | 0.9905 | 0.9031 | 1.0048 | 1.1445 | 0.8949 | 0.9413 | 1.0649 | 0.9753 | 0.9130 | 0.8831 | 0.9333 |
L-proline | 1.0878 | 0.8930 | 0.9233 | 0.9111 | 1.0272 | 0.9527 | 0.9957 | 0.9135 | 1.0934 | 0.9081 | 1.0483 | 1.3306 |
L-serine | 0.9947 | 1.0723 | 0.8066 | 1.1070 | 0.7980 | 0.6162 | 1.2491 | 1.2692 | 0.9586 | 0.9637 | 1.1011 | 1.0688 |
L-threonine | 0.8398 | 1.0653 | 0.9560 | 0.8386 | 0.9624 | 0.9181 | 1.0669 | 1.0821 | 1.1277 | 1.0196 | 1.2236 | 0.9066 |
L-tryptophan | 1.3290 | 1.0477 | 0.9034 | 0.9842 | 1.2851 | 0.8886 | 0.9242 | 0.9597 | 0.9273 | 0.8006 | 0.9288 | 1.0086 |
L-tyrosine | 1.5012 | 0.7310 | 0.7814 | 1.0133 | 1.1228 | 0.8240 | 0.9547 | 1.0833 | 0.9901 | 0.9407 | 0.9646 | 1.1135 |
L-valine | 1.0036 | 0.9854 | 0.9212 | 0.8552 | 1.1711 | 1.0374 | 1.0244 | 0.9282 | 1.1063 | 0.9149 | 0.9369 | 1.1707 |
N-Acetylornithine | 1.4297 | 1.0643 | 1.0649 | 1.0641 | 1.2384 | 1.3362 | 0.7502 | 0.8588 | 0.7602 | 0.8275 | 0.6535 | 0.8803 |
NAD+ | 1.1249 | 0.9208 | 0.9111 | 1.2550 | 0.8343 | 0.6476 | 1.4071 | 1.3620 | 0.6541 | 0.8055 | 0.8692 | 1.1740 |
NADP+ | 0.9436 | 0.7754 | 1.0554 | 1.1884 | 0.8793 | 0.8080 | 1.2748 | 1.1739 | 0.8048 | 1.0200 | 0.9457 | 1.1146 |
Nicotinamide | 0.9522 | 0.9238 | 1.0029 | 0.7907 | 1.1819 | 1.2444 | 0.8072 | 0.8490 | 1.2288 | 1.0233 | 1.0520 | 0.9870 |
Octadecanoyl-L-carnitine (acyl-C18) | 1.1849 | 1.0666 | 1.0491 | 0.9436 | 1.1774 | 1.0584 | 0.9655 | 0.7735 | 0.8657 | 0.9423 | 0.9333 | 1.0161 |
O-Decenoyl-L-carnitine (acyl-C10:1) | 1.8165 | 1.4470 | 0.9106 | 1.1266 | 1.0251 | 0.6049 | 0.8939 | 0.7196 | 0.5129 | 0.7730 | 0.8537 | 1.2736 |
O-dodecanoyl-carnitine (acyl-C12) | 1.2492 | 1.3659 | 1.2889 | 0.7330 | 0.9119 | 0.9507 | 0.9375 | 0.8434 | 1.0459 | 0.9578 | 0.8836 | 0.8017 |
O-dodecenoyl-carnitine (acyl-C12:1) | 1.7869 | 1.5664 | 1.3204 | 0.8157 | 0.8532 | 0.8398 | 0.7448 | 0.5929 | 1.0586 | 0.8251 | 0.8087 | 0.7489 |
O-octadecenoyl-L-carnitine (acyl-C18:1) | 1.1995 | 1.2938 | 1.1532 | 0.8389 | 1.0632 | 1.0466 | 0.8197 | 0.8012 | 1.0543 | 0.9307 | 0.8372 | 0.9655 |
O-tetradecanoyl-L-carnitine (acyl-C14) | 1.0569 | 1.3307 | 1.1181 | 0.8463 | 0.9791 | 0.8409 | 0.9087 | 0.8567 | 1.1617 | 0.9005 | 1.1048 | 0.9100 |
Pantetheine | 0.9548 | 0.8277 | 0.7766 | 0.5025 | 1.5856 | 1.1461 | 0.9747 | 1.1011 | 0.9448 | 0.8000 | 1.4231 | 0.9401 |
Pantetheine 4--phosphate | 0.8915 | 0.9488 | 1.1259 | 0.6089 | 2.0275 | 1.2730 | 0.7928 | 0.8552 | 0.9652 | 0.7711 | 1.0674 | 0.5824 |
Pantothenol | 1.0126 | 1.0405 | 1.0328 | 0.8842 | 1.3978 | 1.2879 | 0.7140 | 0.8066 | 1.0040 | 1.0079 | 0.8218 | 0.9883 |
Phosphoserine | 0.8311 | 0.9546 | 0.9562 | 1.0764 | 1.0871 | 0.9664 | 1.1933 | 0.8959 | 0.9833 | 0.8920 | 1.0890 | 1.0893 |
Picolinic acid | 1.0299 | 0.9838 | 0.9034 | 1.0711 | 1.1284 | 1.0355 | 1.0739 | 0.8571 | 0.9678 | 0.8454 | 1.0421 | 1.0689 |
propionyl-carnitine (acyl-C3) | 0.7800 | 0.8059 | 1.1235 | 0.9022 | 1.2281 | 1.3573 | 0.7546 | 1.0756 | 1.0826 | 1.0259 | 0.9418 | 0.9238 |
Pyridoxamine 5^-phosphate | 1.4116 | 1.0635 | 0.9055 | 1.1675 | 1.0370 | 0.8080 | 0.8243 | 0.9278 | 0.8231 | 0.8713 | 1.2099 | 0.8942 |
S-Adenosyl-L-homocysteine | 1.2043 | 1.1585 | 0.8651 | 0.7141 | 1.2482 | 0.8809 | 0.8781 | 1.1792 | 1.0551 | 0.8879 | 0.9156 | 1.0301 |
S-Adenosyl-L-methionine | 1.0635 | 0.6786 | 1.2308 | 0.9104 | 0.9099 | 0.9945 | 0.9683 | 0.8806 | 1.1277 | 1.1452 | 0.9875 | 1.1607 |
Serotonin | 1.3287 | 1.4224 | 0.7858 | 0.8020 | 0.5717 | 0.5505 | 1.4883 | 1.4973 | 0.9679 | 0.9226 | 0.7362 | 0.9003 |
Spermidine | 1.1285 | 1.0524 | 0.8491 | 0.9843 | 1.1236 | 0.8732 | 1.0866 | 0.8849 | 1.2102 | 0.8195 | 0.7984 | 1.2892 |
Spermine | 1.0245 | 1.0312 | 0.8196 | 1.3845 | 0.9491 | 0.6881 | 1.2508 | 0.8831 | 0.7577 | 0.7697 | 0.9462 | 1.5588 |
Sphingosine | 0.8654 | 0.8772 | 0.7555 | 1.2554 | 0.9546 | 0.9207 | 0.9817 | 1.1308 | 1.0469 | 1.0187 | 1.0766 | 1.1574 |
Tetradecenoyl Carnitine (acyl-C14:1) | 1.2493 | 1.4521 | 1.3310 | 0.8486 | 0.8789 | 0.9252 | 0.8199 | 0.8106 | 1.0082 | 0.8637 | 0.9012 | 0.8914 |
Xanthine | 1.1677 | 0.9255 | 0.8655 | 0.7846 | 1.2157 | 1.0011 | 0.8485 | 0.8097 | 1.1817 | 0.9780 | 1.1658 | 1.1156 |
Factors:
F1 | Treatment:IV iron | Radiation Dose:Gy10 |
F2 | Treatment:IV iron | Radiation Dose:Gy11 |
F3 | Treatment:IV iron | Radiation Dose:Gy7 |
F4 | Treatment:IV iron | Radiation Dose:Gy8 |
F5 | Treatment:IV iron | Radiation Dose:Gy9 |
F6 | Treatment:IV iron | Radiation Dose:no irradiated |
F7 | Treatment:Saline | Radiation Dose:Gy10 |
F8 | Treatment:Saline | Radiation Dose:Gy11 |
F9 | Treatment:Saline | Radiation Dose:Gy7 |
F10 | Treatment:Saline | Radiation Dose:Gy8 |
F11 | Treatment:Saline | Radiation Dose:Gy9 |
F12 | Treatment:Saline | Radiation Dose:no irradiated |