Data for (Study ST002040)

(Analysis AN003319)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12
5-Hydroxyisourate 1.0080 1.0348 0.9045 1.4675 0.8635 1.0885 0.6964 0.9417 0.9333 1.2130 0.7554 1.2171
5-Methylthioadenosine 0.6296 1.2702 1.4077 1.4539 1.0874 1.2330 0.5832 0.5866 0.8565 1.2215 0.6722 1.0750
5-Oxoproline 0.9219 0.9321 0.9679 1.6010 0.9576 1.2368 0.6801 0.9142 0.9041 1.1614 0.7758 1.0600
Acetylcarnitine 0.9631 1.0931 1.0260 1.1591 0.9452 0.7953 0.8823 1.0596 0.8190 1.1672 0.7410 1.4310
Acetylcholine 0.9230 0.4750 0.7276 0.5242 0.8148 0.9481 1.6307 1.1479 1.3353 0.9382 0.8572 1.8126
Adenine 1.1197 1.2733 0.8224 0.6818 0.9203 0.6579 1.2626 1.6922 0.7601 0.8253 1.2782 0.4933
Adenosine 1.3094 2.1241 0.8711 0.5313 1.0289 0.6336 0.7221 1.6853 0.6535 0.8358 0.9011 0.4260
Allantoate 0.8625 0.6445 1.1958 0.7339 0.9643 1.8369 1.0197 0.7271 1.0742 0.9479 0.7867 1.2101
alpha-D-Glucosamine 1-phosphate 1.1060 1.0252 1.2290 0.6972 0.8845 1.1840 0.8165 1.1192 0.8965 0.8357 0.9155 1.2618
AMP 0.8905 0.7605 1.4942 1.3687 1.0592 0.9080 0.8053 0.4800 1.2024 1.3954 0.7024 1.0597
Argininosuccinate 1.1263 1.0109 0.7200 1.6176 1.2381 1.4268 0.2779 0.6969 0.3719 1.4512 0.8750 1.2317
Asymmetric dimethyl arginine 0.9489 0.8203 1.1612 1.2098 1.2126 1.2413 0.7296 0.7739 0.7963 0.9624 0.7951 1.4374
Butyrylcarnitine 1.3607 0.6675 0.4412 0.5514 0.6607 0.2239 2.0272 2.4590 0.9498 1.0111 0.9998 0.4350
Carnosine 0.7961 0.6303 1.1906 3.2673 0.6967 1.6444 0.5469 0.5019 0.6234 1.0743 0.5271 0.8488
Creatine 0.9349 0.8451 1.2309 1.1487 0.9715 1.1879 0.8186 0.8896 0.7257 0.9818 0.9146 1.4069
Creatinine 0.9563 0.7895 0.9567 1.0120 0.9592 1.0436 1.2938 0.8212 1.0306 0.9306 1.0106 1.2555
Cys-Gly 0.8626 0.8989 1.2011 0.8458 0.9202 1.0117 1.1313 0.9999 0.9167 1.0955 1.0756 0.9915
Cytosine 0.9615 1.0965 0.7516 3.0934 0.7589 0.7734 0.5499 1.5285 0.6441 0.7930 0.8241 0.4658
dAMP 0.5710 0.7609 0.9995 3.5072 0.6015 0.3226 1.0512 0.7359 0.7599 1.4846 0.7792 0.8498
Decanoylcarnitine 0.7979 0.4834 1.8223 0.7656 0.7557 1.1770 0.6200 0.3892 1.3222 1.0556 0.5843 2.5049
Dimethylglycine 1.1416 0.7749 1.2074 0.8864 1.1206 1.3237 0.8504 0.7254 0.7939 0.8356 0.7690 1.6338
Dodecanoylcarnitine 1.2083 0.5690 1.4318 1.1785 0.8166 0.7218 0.7334 0.8055 1.2413 0.9784 0.6682 1.9139
Flavin mononucleotide 0.9168 0.9300 1.1420 0.9277 1.0479 1.0949 1.1300 1.0963 0.9231 0.7478 1.0303 0.9612
gamma-Glutamyl-gamma-aminobutyrate 0.8847 0.5305 1.1818 1.2317 0.8994 1.2486 1.2087 0.8927 1.1911 0.9712 1.0522 0.7400
gamma-Glutamyl-Se-methylselenocysteine 0.9431 0.8579 0.3409 0.7335 0.7020 1.0500 1.0876 2.2209 0.9883 0.6122 1.4535 0.7919
gamma-L-Glutamyl-D-alanine 1.0299 0.7112 1.2390 0.9448 0.9226 1.1873 0.7296 1.1034 0.9643 0.9141 1.3972 0.7981
gamma-L-Glutamyl-L-cysteine 0.9276 1.2180 1.4594 0.9501 1.0307 1.3118 0.5601 0.8958 0.7491 1.1073 0.9106 0.7741
gamma-L-Glutamylputrescine 0.1511 0.1329 1.5713 7.6915 0.1260 1.7746 0.1763 0.0571 0.2868 0.8085 0.1002 0.1490
Glutathione 0.9521 0.9608 1.0684 0.9462 0.9922 0.8601 1.0295 0.9970 0.9642 1.1993 1.0231 0.9865
Glutathione disulfide 0.9995 1.1460 0.8234 0.8762 1.1155 0.9758 0.7842 1.2973 0.9443 0.8056 1.1787 1.0220
glycine 0.9393 0.8458 1.1648 1.2977 0.9928 1.2246 0.6769 0.8647 0.8856 1.0524 0.8949 1.2463
g-Oxalo-crotonate 1.1214 1.2413 0.5608 0.6683 0.8860 1.0131 0.8071 1.4993 0.9398 0.7410 1.0108 1.5409
Guanidinoacetate 0.7412 0.6123 1.4102 0.6526 0.6716 1.7133 0.7382 1.0630 0.9055 0.9058 0.8075 1.8632
Guanine 0.8939 1.0117 1.0436 1.5249 0.8277 1.3204 0.7861 0.9777 0.8301 0.9268 1.0126 0.8944
Guanosine 1.1177 1.8317 0.6213 0.4942 1.0117 0.9177 0.7019 1.8789 0.7941 0.7108 1.1620 0.5195
Hexadecadienoylcarnitine 0.7455 0.3291 2.2166 1.8751 0.6570 0.8846 0.5521 0.5806 1.1733 0.9634 0.4153 2.0214
Hexanoylcarnitine 1.1159 1.0330 1.2918 1.0032 0.7450 0.5343 0.8509 1.2387 1.1856 1.2416 0.5696 1.2853
Hydroxydecanoyl carnitine 0.6942 1.0145 1.3398 1.1758 0.9979 1.1973 0.3783 0.6905 0.6984 1.0527 0.7063 2.2865
Hydroxydodecanoyl carnitine 0.8098 1.0451 1.4179 0.8900 1.0359 1.2726 0.3412 0.6403 0.6952 1.1053 0.7337 2.1627
Hydroxyhexadecanoyl carnitine 0.7815 1.0527 1.2238 0.9677 1.1447 1.3744 0.2882 0.5876 0.7246 1.0353 0.6430 2.3937
Hydroxyhexanoyl carnitine 2.9075 0.7186 0.8079 0.6581 0.8132 0.6870 1.0433 0.8023 0.8783 0.7962 0.9874 0.7592
Hydroxyisovaleroyl carnitine 1.1373 0.8105 1.0987 1.0330 1.0063 1.1453 0.8625 0.9727 0.8910 0.9601 0.7818 1.3569
Hydroxyoctanoyl carnitine 0.6841 1.0417 1.3444 1.0041 0.9258 1.1573 0.5743 0.8195 0.8960 1.2037 0.6184 1.8884
Hydroxypropionylcarnitine 0.8729 0.5437 1.6386 0.6304 0.6405 1.7085 0.9279 0.9069 0.6210 0.6731 0.8890 1.9975
Hydroxytetradecanoyl carnitine 0.8217 0.8418 1.2197 1.2851 0.9786 1.4007 0.3231 0.5701 0.5487 1.0778 0.6277 2.5896
Hydroxyundecanoyl carnitine 1.0719 0.4105 1.1085 2.3209 0.6140 0.4292 1.3130 1.4285 1.5502 0.5217 0.7515 1.0237
Hypotaurine 1.5036 1.0813 0.5606 0.8778 1.1588 0.3685 1.1677 1.5561 1.0477 0.7721 1.4076 0.3541
Hypoxanthine 1.1070 1.2456 0.5435 0.7802 0.9554 1.2394 0.6907 1.5188 0.8864 0.7425 1.0667 1.1964
IMP 0.8790 1.5042 1.1319 1.5676 1.2067 1.6062 0.5076 0.5860 0.6946 1.2134 0.6014 0.4421
Indole 0.5107 0.5335 1.2993 3.4106 0.6876 1.6441 0.4023 0.3539 0.4829 1.4527 0.4390 1.0412
Indoxyl 1.0831 0.3302 0.0973 0.2243 0.8558 0.3334 3.5492 1.4761 1.6351 0.2585 1.7606 0.2103
Inosine 0.9189 1.6246 0.5160 0.6117 0.9264 1.2211 0.4808 2.0899 0.6855 0.9011 1.3601 0.4040
Isovalerylcarnitine 1.6778 0.9433 0.4787 0.8109 1.1096 0.3685 1.4248 1.6158 0.8904 0.8275 1.1518 0.5514
Kynurenic acid 0.7755 0.4097 0.2788 0.5339 0.7663 0.4620 2.8794 1.4393 1.6283 0.5466 1.6922 0.5258
Kynurenine 0.5504 0.7377 0.4810 0.9375 0.7845 0.3407 1.2382 2.8772 0.8914 1.0716 1.5569 0.3734
L-alanine 0.9756 0.7219 1.1179 1.3653 1.0253 1.2721 0.7214 0.8596 0.9028 1.1109 0.9598 1.0262
L-arginine 0.3456 0.3696 1.0740 6.2006 0.4638 1.2869 0.2725 0.3202 0.3788 1.2633 0.3169 0.5296
L-asparagine 0.5074 0.4350 1.3563 3.1085 0.5926 1.6955 0.5361 0.3667 0.4878 1.6170 0.4949 1.1519
L-aspartate 0.7722 0.5378 0.9544 1.5645 0.9571 1.1271 0.9995 0.8707 0.9706 1.1630 0.8189 1.4640
L-Carnitine 1.0160 0.9517 1.2520 1.1434 0.9912 1.1535 0.6316 1.0447 0.7994 1.1335 0.6992 1.2153
L-Citrulline 0.7168 0.3597 1.5601 1.0098 0.7072 1.5704 0.8200 0.6614 0.7559 1.2485 0.8390 1.8805
L-cysteine 0.8525 0.7664 1.5274 1.9029 0.7336 1.5881 0.4833 0.8983 0.4837 1.1273 0.7921 0.9020
L-cystine 0.6366 0.4928 1.6132 2.5888 0.7400 2.3416 0.1681 0.8049 0.3754 0.6614 0.5707 1.2493
L-glutamate 0.9366 0.8292 0.9436 1.4410 1.0188 1.2064 0.8247 1.0904 0.9870 1.0421 0.8496 0.8952
L-glutamine 0.8545 0.9951 0.9765 1.8131 0.9166 1.2256 0.5738 0.8103 0.8389 1.2053 0.7092 1.2644
L-histidine 0.6501 0.6244 1.1631 2.8181 0.8427 1.5055 0.4322 0.5206 0.6290 1.4821 0.5449 1.0961
Linoelaidyl carnitine 0.7616 0.5219 2.0336 1.3475 0.9044 0.9474 0.5665 0.6439 1.0440 0.9492 0.5134 2.0562
L-leucine 0.8516 0.7496 1.5010 0.6092 0.8950 1.6743 0.6884 0.6717 0.7740 1.4949 0.6813 1.2592
L-lysine 0.5362 0.5958 1.3337 3.2641 0.7768 1.5892 0.4518 0.4523 0.6254 1.3681 0.5486 0.7949
L-methionine 0.8464 0.6530 1.1536 1.7904 0.8643 1.3975 0.7881 0.8008 0.7911 1.0670 0.7808 1.2291
L-phenylalanine 0.5643 0.5400 1.2931 3.5749 0.7432 1.5738 0.4830 0.4494 0.5391 1.3003 0.4583 0.8793
L-proline 0.8726 0.7035 1.2672 1.6776 0.9602 1.3307 0.6263 0.7113 0.6954 1.1308 0.7470 1.4399
L-serine 0.6787 0.6130 1.2440 2.7284 0.8480 1.4732 0.4111 0.5966 0.6928 1.2791 0.5629 1.1954
L-threonine 0.6525 0.6655 1.1000 2.1389 0.8535 1.4143 0.6548 0.7001 0.8200 1.2226 0.8046 1.2064
L-tryptophan 0.5806 0.6235 1.4108 3.0905 0.7631 1.6279 0.3934 0.3748 0.5093 1.4328 0.4341 1.0991
L-tyrosine 0.7988 0.6511 1.2707 1.9870 0.8414 1.4882 0.7078 0.6524 0.7672 1.1931 0.6708 1.1531
L-valine 0.9484 0.7086 1.2531 1.5315 1.0215 1.0719 0.8791 0.8663 0.8520 1.0783 0.8367 1.0369
Malonylcarnitine 1.1519 0.8392 0.7890 0.8631 0.9274 1.1590 1.1925 1.0771 1.3091 0.8566 1.1567 0.5580
Methylglutarylcarnitine 1.3141 1.8571 1.6795 1.1831 2.0129 0.6492 0.0830 0.3792 0.5156 1.2555 0.5159 0.3681
Methylmalonylcarnitine 0.6331 0.8303 1.6288 0.9770 0.8717 1.1779 0.6239 0.6970 0.8117 1.2093 0.5637 2.1667
N-Acetyl-L-citrulline 0.1030 NA 1.6986 4.4635 0.0685 1.6668 0.2955 0.1359 0.2851 0.9196 0.1665 0.6562
N-Acetyl-L-ornithine 1.0605 0.6782 1.1001 1.2775 0.9014 1.4870 0.9964 0.8259 0.9187 1.0038 0.8213 0.9606
NAD+ 0.7451 0.2537 1.1038 1.2463 0.8812 0.7856 2.0162 0.1925 1.8983 0.7383 0.6573 1.4525
Nicotinamide 0.8973 1.1230 1.2465 0.9440 1.0168 1.3687 0.7405 0.6532 0.7623 1.0957 0.7719 1.4018
Nicotinic acid 1.7774 0.4795 0.2337 0.5292 1.0443 0.4540 1.5961 2.1142 1.1296 0.4651 1.6429 0.3323
Octanoylcarnitine 0.7711 0.5744 1.6742 1.1022 0.6924 0.8754 0.6299 0.6183 1.4248 1.2004 0.6150 2.1590
Octenoylcarnitine 1.2692 0.9262 1.2459 0.9252 0.8445 0.6605 0.9217 0.8989 0.9509 1.0202 0.9090 1.5038
Ornithine 0.6212 0.4501 1.5062 1.0298 0.8543 2.9083 0.6551 0.4741 0.7812 1.0986 0.5529 1.0379
Palmitoylcarnitine 0.9338 0.7388 1.1615 1.2256 1.1746 1.0351 0.7033 0.6950 1.0391 1.0381 0.7060 1.7525
Pantetheine 1.2480 0.9196 0.9700 1.1329 0.7050 1.2480 1.1099 1.1735 0.8654 0.8473 0.9982 0.7275
Pantetheine 4--phosphate 1.1456 0.9646 0.9493 0.6430 0.8569 1.1168 1.1507 1.5182 0.8075 0.9044 1.1844 0.5609
Phosphocreatine 0.4748 0.1083 0.7929 0.2789 1.3404 0.2792 1.3450 0.0792 1.7996 0.4652 0.6502 5.2525
Phosphoethanolamine 0.9306 1.0194 1.0580 0.9744 1.0274 0.9489 0.7549 1.2458 0.8152 1.1720 0.7229 1.3605
Phosphoserine 0.9945 0.9699 0.7014 0.8364 0.9903 0.9117 1.1190 1.3195 1.2714 0.9862 1.0830 0.7978
Propanoyl-carnitine 2.7046 0.8462 0.1508 0.4129 0.9902 0.1606 0.9282 1.6627 0.8027 0.7827 1.1095 1.3649
Putrescine 1.1539 1.0711 1.1662 1.1578 0.8500 0.8152 1.0070 1.0971 0.7606 1.3059 0.9902 0.5106
Pyridoxal 0.9329 0.5548 0.7727 0.7646 0.6814 0.5008 2.0748 1.1952 1.6630 0.6987 1.6827 0.4548
S-Adenosyl-L-homocysteine 0.9993 0.9863 0.9611 1.0498 0.9718 0.9554 0.8178 0.7780 0.9668 1.3556 1.0216 1.1871
S-Adenosyl-L-methionine 0.5437 1.3190 1.4134 1.5360 0.8582 1.4232 0.5346 0.4724 0.8821 1.3452 0.7174 1.0480
Serotonin 1.3195 0.6678 1.1320 0.9175 0.8720 0.9583 1.1284 1.0088 1.4374 1.2290 0.4827 0.8968
sn-glycero-3-Phosphoethanolamine 0.5493 0.8913 0.9806 0.8975 0.7690 1.5089 0.8348 0.8891 0.8719 0.9707 0.6265 2.4553
Spermidine 0.9512 0.9686 0.7211 1.9157 0.8575 1.0185 1.0371 1.0256 0.9174 1.1006 0.9601 0.6166
Spermine 0.7093 1.1386 0.4401 1.4432 0.9936 0.9625 0.7917 0.7508 0.4417 0.9030 0.6278 3.2184
Sphingosine 0.4022 0.5924 1.4962 3.6909 0.7177 1.7423 0.5155 0.5449 0.4972 0.9560 0.4734 0.7611
Taurine 1.0095 1.0479 1.0416 1.0160 1.0895 1.1181 0.8869 0.8959 0.9909 1.0097 0.9244 0.9638
Xanthine 1.1324 1.1210 0.6517 0.6239 1.0117 0.9703 0.9747 1.3963 0.8562 0.7696 1.0372 1.4388
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Factors:

F1Condition:IV iron | Radiation Dose:Gy10
F2Condition:IV iron | Radiation Dose:Gy11
F3Condition:IV iron | Radiation Dose:Gy7
F4Condition:IV iron | Radiation Dose:Gy8
F5Condition:IV iron | Radiation Dose:Gy9
F6Condition:IV iron | Radiation Dose:no irradiated
F7Condition:Saline | Radiation Dose:Gy10
F8Condition:Saline | Radiation Dose:Gy11
F9Condition:Saline | Radiation Dose:Gy7
F10Condition:Saline | Radiation Dose:Gy8
F11Condition:Saline | Radiation Dose:Gy9
F12Condition:Saline | Radiation Dose:no irradiated
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