Data for (Study ST002040)
(Analysis AN003320)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1-3-Bisphosphoglycerate | 0.8679 | 0.5647 | 0.6492 | 0.2567 | 1.4158 | 0.4123 | 0.6803 | 0.5610 | 0.3796 | 0.3145 | 1.2832 | 4.3091 |
| 2/3-Phospho-D-glycerate | 1.1666 | 0.7142 | 0.7753 | 0.6603 | 1.0924 | 0.8095 | 1.6752 | 0.6385 | 1.0936 | 0.7353 | 1.1596 | 1.5380 |
| 2-Aminomuconate | 1.0031 | 0.6661 | 0.5658 | 0.8207 | 0.9313 | 0.7408 | 1.9742 | 1.0868 | 1.5087 | 0.6027 | 1.0767 | 1.1110 |
| 2-Hydroxyglutarate | 1.0497 | 0.6840 | 0.5722 | 0.5333 | 1.0165 | 1.0430 | 1.8510 | 0.9970 | 1.3101 | 0.6343 | 1.4778 | 0.7498 |
| 2-Oxoglutaramate | 1.2002 | 0.8158 | 0.9349 | 1.0040 | 0.9789 | 0.9042 | 1.2816 | 1.0052 | 1.0240 | 0.6179 | 1.1626 | 1.0955 |
| 2-Oxoglutarate | 0.9086 | 1.0654 | 1.1436 | 0.9727 | 0.9731 | 1.3074 | 0.8095 | 1.0592 | 0.9093 | 0.8408 | 0.7512 | 1.2944 |
| 3-Methyldioxyindole | 1.1650 | 0.1167 | 0.0773 | 0.1017 | 0.1874 | 0.1019 | 3.4689 | 1.3080 | 2.2584 | 0.1335 | 2.8754 | 0.0971 |
| 3-Sulfocatechol | 1.3985 | 0.4507 | 0.1910 | 0.2009 | 0.3842 | 0.5138 | 2.6810 | 1.2568 | 1.3878 | 0.2090 | 1.6281 | 1.3412 |
| 4-Pyridoxate | 0.8861 | 0.9866 | 1.2015 | 0.9730 | 1.0564 | 1.0173 | 0.5899 | 0.6604 | 0.8215 | 1.5302 | 0.9427 | 1.3666 |
| 5-6-Dihydrothymine | 0.8852 | 1.1423 | 0.9110 | 1.7001 | 0.8116 | 1.1266 | 0.7276 | 0.8772 | 0.9109 | 1.0364 | 0.7396 | 1.3171 |
| (5-L-Glutamyl)-L-glutamine | 0.6740 | 0.9718 | 1.2047 | 2.5596 | 0.7173 | 1.3301 | 0.4821 | 0.9159 | 0.8822 | 1.1631 | 0.6980 | 0.6121 |
| 5-L-Glutamyl-taurine | 1.8997 | 0.8884 | 0.7246 | 0.8299 | 1.4002 | 0.9271 | 0.7408 | 1.3053 | 0.7940 | 0.4690 | 1.0753 | 0.8383 |
| 6-Phospho-D-gluconate | 1.2948 | 0.8754 | 0.6070 | 1.0449 | 1.2154 | 1.1666 | 0.9998 | 1.0606 | 0.8846 | 1.0308 | 1.0434 | 0.7034 |
| (7Z-10Z-13Z-16Z-19Z)-Docosa-7-10-13-16-19-pentaenoic acid | 0.8134 | 0.8174 | 1.1427 | 1.2601 | 1.1575 | 1.4754 | 0.8283 | 0.8575 | 0.9875 | 0.7352 | 0.9490 | 1.0320 |
| (8Z-11Z-14Z)-Icosatrienoic acid | 0.8988 | 0.8587 | 0.7313 | 1.2512 | 1.1345 | 1.0754 | 0.9008 | 1.1257 | 0.9747 | 0.6833 | 1.0097 | 1.5015 |
| Adenylosuccinic acid | 1.1973 | 1.1828 | 0.8932 | 1.0268 | 1.4301 | 1.5164 | 0.3504 | 0.9097 | 0.4914 | 1.3623 | 0.8672 | 0.5950 |
| ADP | 1.1596 | 1.2316 | 1.2156 | 0.9569 | 1.3237 | 0.7910 | 1.0081 | 0.9661 | 0.8239 | 0.8461 | 0.7458 | 0.8597 |
| ADP-D-ribose | 0.3987 | 0.2479 | 1.4422 | 1.1616 | 0.7418 | 1.6028 | 1.2909 | 0.1895 | 1.0801 | 1.6067 | 0.6745 | 1.7647 |
| alpha-D-Ribose 1-phosphate | 0.9460 | 1.5042 | 0.7161 | 0.7358 | 1.1435 | 1.0944 | 0.5395 | 1.6944 | 0.5768 | 0.8828 | 1.3133 | 0.6447 |
| Ascorbate | 1.0546 | 1.2215 | 1.4373 | 0.9857 | 1.0067 | 0.9317 | 0.7094 | 0.9455 | 0.8807 | 1.0194 | 0.8429 | 0.9223 |
| ATP | 0.9667 | 0.9475 | 2.0944 | 0.7884 | 1.5942 | 0.5308 | 1.0278 | 0.6057 | 0.8327 | 0.6817 | 0.5455 | 1.3863 |
| Butanoic acid | 0.5280 | 0.0540 | 0.0240 | 0.0379 | 0.3008 | 0.0444 | 4.9888 | 2.0471 | 2.2063 | 0.1206 | 1.4720 | 0.0310 |
| CDP | 1.2865 | 1.2541 | 1.3151 | 0.9726 | 1.3724 | 0.7762 | 1.0141 | 0.8653 | 0.9696 | 0.7294 | 0.5885 | 0.7989 |
| Citrate | 1.0476 | 1.2700 | 0.9390 | 0.9140 | 1.1527 | 1.0127 | 1.0332 | 1.0754 | 0.9121 | 0.7738 | 1.0625 | 0.7154 |
| CMP-N-acetylneuraminate | 1.1702 | 1.2708 | 0.7976 | 0.9193 | 1.2726 | 1.1031 | 0.8072 | 1.0380 | 0.8976 | 0.8675 | 0.9720 | 0.8096 |
| Cystathionine | 1.1236 | 0.8947 | 0.6150 | 0.6428 | 0.8537 | 0.7570 | 1.4213 | 1.5941 | 1.0380 | 1.0434 | 1.3714 | 0.4764 |
| D-Arabitol/Xylitol/Ribitol | 0.8776 | 0.8562 | 1.0828 | 0.7846 | 1.0986 | 1.5741 | 0.7926 | 0.8075 | 0.9523 | 0.7342 | 0.9606 | 1.5327 |
| Decanoic acid (caprate) | 0.8556 | 1.1218 | 0.9985 | 0.8341 | 0.9441 | 1.0804 | 0.9429 | 1.1091 | 1.0406 | 0.8500 | 0.8381 | 1.4497 |
| Dehydroascorbate | 0.9537 | 1.0185 | 1.2733 | 1.1203 | 0.9588 | 1.4022 | 0.7370 | 0.9556 | 0.8590 | 0.8544 | 0.7476 | 1.1444 |
| D-Fructose 1-6-bisphosphate | 0.8221 | 1.5364 | 0.7451 | 0.7137 | 1.6396 | 0.9624 | 0.4613 | 1.2333 | 0.5888 | 0.7934 | 1.4444 | 0.9001 |
| D-Glucono-1-5-lactone 6-phosphate | 0.8807 | 0.6272 | 0.5162 | 0.5536 | 0.8702 | 0.9925 | 1.4480 | 1.9506 | 1.0349 | 0.7333 | 1.1095 | 1.2513 |
| D-Glucoronate | 0.8593 | 0.6230 | 0.9400 | 1.4331 | 0.9941 | 1.1435 | 1.0658 | 1.0258 | 1.1873 | 0.7631 | 1.2772 | 0.7648 |
| D-Glucose | 0.9079 | 1.0902 | 0.7415 | 0.8944 | 1.0631 | 1.1990 | 0.9281 | 0.8906 | 0.9400 | 0.7857 | 0.6791 | 2.0592 |
| D-Glyceraldehyde 3-phosphate/Glycerone phosphate | 0.9661 | 1.5456 | 0.6675 | 0.7967 | 1.1535 | 1.0950 | 0.5977 | 1.3996 | 0.6628 | 0.8999 | 1.0620 | 1.0568 |
| dGMP | 1.0324 | 0.8583 | 1.3874 | 1.3892 | 1.0248 | 0.8297 | 0.8246 | 0.6054 | 1.0715 | 1.2895 | 0.6899 | 1.1117 |
| Diphosphate | 0.9999 | 1.1384 | 1.0818 | 0.7846 | 1.1156 | 1.1614 | 0.7442 | 1.1360 | 0.7475 | 0.9439 | 1.1335 | 0.8993 |
| Docosahexaenoic acid | 0.8962 | 0.8926 | 1.1346 | 1.5241 | 1.0580 | 1.4992 | 0.8192 | 0.8061 | 0.9091 | 0.7360 | 0.8159 | 0.9945 |
| Dodecanedioic acid | 0.9506 | 0.2801 | 0.2025 | 0.3499 | 0.6276 | 0.3235 | 2.9234 | 1.5684 | 1.8366 | 0.3192 | 1.8410 | 0.5689 |
| Dodecanoic acid | 0.8858 | 0.9246 | 0.9420 | 0.8544 | 1.0054 | 1.0870 | 0.9431 | 0.9072 | 1.0319 | 0.9096 | 1.0256 | 1.5759 |
| D-Rhamnose | 0.6073 | 0.6064 | 0.6876 | 0.7464 | 0.8681 | 1.5484 | 3.0416 | 0.8125 | 0.8766 | 0.6632 | 0.9530 | 0.3917 |
| D-Ribose | 0.5833 | 0.5984 | 1.2435 | 1.8290 | 0.6176 | 2.7031 | 0.6185 | 0.7089 | 0.8927 | 0.7247 | 0.7836 | 0.8014 |
| Eicosapentaenoic acid | 0.8004 | 0.6362 | 1.6277 | 1.1217 | 1.0005 | 1.9365 | 0.6308 | 0.6242 | 0.8507 | 0.7102 | 0.7342 | 1.4015 |
| Eicosatetraenoic acid | 1.0240 | 0.8929 | 1.1666 | 1.4417 | 1.1130 | 1.2765 | 0.8532 | 0.8475 | 0.8804 | 0.7675 | 0.9196 | 0.8518 |
| Fumarate | 1.4743 | 1.3560 | 0.7770 | 0.9509 | 1.1699 | 1.2759 | 0.5030 | 1.0959 | 0.6769 | 0.8666 | 0.8174 | 0.9523 |
| GDP | 1.2252 | 1.2407 | 1.5051 | 0.7108 | 1.4580 | 0.7432 | 0.9327 | 0.8133 | 0.8671 | 0.8166 | 0.7402 | 0.8284 |
| Glycerol 3-phosphate | 1.0885 | 0.6487 | 1.1418 | 0.8220 | 0.9604 | 0.7902 | 1.4960 | 0.9903 | 1.4815 | 1.0581 | 1.0470 | 0.4201 |
| GMP | 1.1707 | 1.0794 | 1.0630 | 1.0736 | 1.2286 | 1.0474 | 0.8643 | 0.7162 | 0.8370 | 1.1000 | 0.8827 | 0.8989 |
| Heptanoic acid | 0.9438 | 1.0479 | 0.8705 | 0.9026 | 0.9018 | 1.0453 | 1.0152 | 1.2690 | 0.9225 | 0.8253 | 0.8920 | 1.4111 |
| Hexadecanoic acid | 0.8091 | 0.7473 | 1.1562 | 0.8300 | 1.1613 | 1.2387 | 0.8247 | 0.8256 | 0.9269 | 0.9103 | 1.0733 | 1.5599 |
| Hexadecenoic acid | 0.5040 | 0.4297 | 1.1607 | 0.5481 | 1.4566 | 1.3579 | 0.6500 | 0.5742 | 0.9290 | 0.6545 | 1.2089 | 2.7773 |
| Hexanoic acid (caproate) | 0.7940 | 1.0015 | 0.8196 | 0.8208 | 0.8933 | 1.0152 | 1.2001 | 1.2526 | 0.9855 | 0.8026 | 0.8542 | 1.6526 |
| Indole-3-acetate | 1.1844 | 1.6606 | 0.7532 | 1.9223 | 1.1861 | 0.8487 | 0.4503 | 0.8498 | 1.2576 | 1.0461 | 0.7125 | 0.2056 |
| Indolepyruvate | 0.9080 | 0.6687 | 1.0726 | 1.7876 | 0.9185 | 1.3758 | 0.7934 | 0.6580 | 0.9166 | 1.1824 | 0.7008 | 1.1980 |
| Itaconate | 0.9601 | 1.0579 | 1.1499 | 0.9011 | 0.9484 | 1.3591 | 0.7717 | 1.0697 | 0.8711 | 0.8164 | 0.7811 | 1.3349 |
| Lactate | 1.1232 | 0.9412 | 1.1841 | 1.0656 | 0.8832 | 1.2226 | 0.6190 | 0.9526 | 0.8649 | 0.9065 | 0.8646 | 1.4483 |
| Malate | 1.2667 | 1.1684 | 0.8189 | 1.0645 | 1.1535 | 1.2224 | 0.5477 | 1.0760 | 0.7970 | 0.9490 | 0.8955 | 1.0159 |
| Maltose/Sucrose | 0.8268 | 0.3071 | 0.4153 | 1.1189 | 0.4880 | 0.7429 | 2.5881 | 1.2296 | 1.6667 | 0.6627 | 1.4045 | 0.5354 |
| Mannitol/Sorbitol | 0.7538 | 0.5117 | 1.4420 | 2.7230 | 0.7294 | 1.6442 | 0.6096 | 0.4663 | 0.5866 | 1.1465 | 0.5919 | 1.0710 |
| N-acetyl-D-glucosamine | 1.1534 | 1.0587 | 1.3301 | 0.8820 | 0.9819 | 1.0534 | 0.7560 | 1.1933 | 0.8812 | 0.7478 | 0.9046 | 1.0127 |
| N-Acetylneuraminate | 0.9307 | 1.0208 | 0.6556 | 0.9995 | 1.0933 | 1.1221 | 0.9381 | 0.8587 | 1.2555 | 0.6275 | 0.7162 | 2.0411 |
| N-Glycoloyl-neuraminate | 0.8031 | 1.0287 | 0.5882 | 0.8850 | 1.3843 | 0.8751 | 1.3039 | 1.0670 | 1.4203 | 0.5894 | 1.1107 | 1.0067 |
| Nonanoic acid (pelargonate) | 0.8575 | 1.1217 | 0.9840 | 0.9120 | 0.9055 | 1.0213 | 0.9250 | 1.1122 | 1.0419 | 0.8933 | 0.9098 | 1.3831 |
| Octadecadienoic acid | 0.7221 | 0.6219 | 1.7166 | 1.0933 | 1.0580 | 1.4252 | 0.7463 | 0.6662 | 0.9146 | 0.7356 | 0.8546 | 1.5589 |
| Octadecanoic acid | 0.9370 | 0.8171 | 1.4870 | 1.2801 | 1.1428 | 1.2659 | 0.9056 | 0.4364 | 1.0523 | 0.6239 | 0.8450 | 1.3417 |
| Octadecatrienoic acid | 0.4607 | 0.3295 | 2.1698 | 0.4411 | 0.9642 | 2.0973 | 0.6298 | 0.5259 | 0.8956 | 0.6004 | 0.9983 | 1.9434 |
| Octadecenoic acid | 0.8213 | 0.6877 | 1.1609 | 0.7202 | 1.1867 | 1.2083 | 0.9645 | 0.7908 | 0.9449 | 0.8049 | 1.2099 | 1.5412 |
| Octanoic acid (caprylate) | 0.8589 | 1.0296 | 0.9375 | 0.8942 | 0.9635 | 1.0842 | 0.8993 | 1.2115 | 0.9370 | 0.7822 | 0.8736 | 1.6185 |
| Oxaloacetate | 0.8215 | 1.0854 | 1.0418 | 0.9749 | 1.0214 | 0.9226 | 1.1140 | 1.1313 | 1.1022 | 0.8797 | 0.9106 | 1.0126 |
| Pentanoate (valerate) | 0.8713 | 0.2691 | 0.1565 | 0.2483 | 1.0032 | 0.2015 | 3.4322 | 2.4903 | 1.7079 | 0.2470 | 1.0257 | 0.1727 |
| Phosphate | 0.9936 | 1.1303 | 1.0717 | 0.8839 | 1.0839 | 1.1857 | 0.8316 | 1.0780 | 0.7526 | 0.8836 | 1.0452 | 0.9840 |
| Phosphodimethyl-ethanolamine | 0.9304 | 0.8467 | 1.6094 | 1.0224 | 0.9233 | 1.1084 | 0.7258 | 0.8435 | 0.7422 | 1.1614 | 0.6920 | 1.4342 |
| Phosphoenolpyruvate | 1.5605 | 0.6647 | 0.5151 | 0.6662 | 1.2498 | 0.7531 | 1.7606 | 0.8797 | 0.9376 | 0.5058 | 1.1517 | 1.2833 |
| Pyruvate | 1.2720 | 1.2876 | 0.9986 | 1.0398 | 0.8959 | 1.1860 | 0.6108 | 0.8826 | 0.9044 | 0.7217 | 0.7063 | 1.6040 |
| Quinolinic acid | 0.9948 | 0.4739 | 0.7255 | 0.5446 | 0.9276 | 0.8713 | 1.3891 | 0.8480 | 0.9061 | 0.4380 | 1.2177 | 2.9420 |
| (S)(+)-Allantoin | 0.8760 | 1.0679 | 0.9492 | 1.1709 | 1.2032 | 1.6300 | 0.6848 | 0.6848 | 0.7248 | 0.8746 | 0.7346 | 1.4728 |
| Sedoheptulose 1-phosphate | 1.0933 | 1.0134 | 0.5162 | 0.5808 | 0.9422 | 1.1233 | 0.9263 | 1.8590 | 0.8722 | 0.6648 | 1.3071 | 0.9901 |
| S-Glutathionyl-L-cysteine | 1.0376 | 1.1838 | 1.0286 | 1.0764 | 1.1405 | 1.2363 | 0.5785 | 1.1210 | 0.7129 | 0.7767 | 1.0002 | 1.0818 |
| Sphinganine 1-phosphate | 0.9178 | 0.8515 | 1.7128 | 1.1145 | 1.2535 | 1.1269 | 0.8989 | 0.4043 | 1.0596 | 0.6448 | 0.9371 | 1.1413 |
| Sphingosine 1-phosphate | 0.8967 | 0.8065 | 1.1207 | 0.8034 | 1.0908 | 1.2624 | 0.9841 | 0.8932 | 0.9404 | 0.8998 | 1.0394 | 1.2641 |
| Succinate | 0.8425 | 0.1662 | 1.6098 | 1.0223 | 0.7271 | 0.5523 | 1.5351 | 0.5419 | 1.5713 | 1.5262 | 0.9608 | 1.0788 |
| Tetradecanoic acid | 0.6824 | 0.4894 | 1.0603 | 0.4477 | 1.3114 | 1.0296 | 0.9512 | 0.7286 | 1.1613 | 0.8186 | 1.3122 | 2.1614 |
| Tetradecenoic acid | 0.5906 | 0.6666 | 0.7773 | 0.4272 | 1.2717 | 0.9609 | 0.7211 | 0.7201 | 0.9699 | 0.6661 | 1.5262 | 2.9771 |
| Thymine | 0.8556 | 0.4525 | 0.3586 | 2.7667 | 1.1719 | 0.4219 | 1.7150 | 0.9000 | 1.0714 | 0.6514 | 1.3908 | 0.5149 |
| trans-4-Hydroxy-L-proline | 0.9201 | 0.7931 | 0.8971 | 1.5905 | 0.8822 | 1.0308 | 0.9964 | 1.0169 | 1.0113 | 0.8960 | 0.9486 | 1.1716 |
| UDP | 1.1967 | 0.9964 | 1.4140 | 0.9443 | 1.3050 | 0.7603 | 1.2288 | 0.6093 | 0.8841 | 0.7333 | 0.5056 | 1.4847 |
| UDP-D-glucuronate | 0.8395 | 0.7393 | 1.3626 | 1.1427 | 1.3137 | 1.0084 | 0.6381 | 0.6101 | 1.0532 | 1.3845 | 0.8100 | 1.1713 |
| UDP-glucose | 0.7054 | 0.9353 | 1.3439 | 1.4231 | 1.0101 | 1.4683 | 0.8173 | 0.3930 | 0.9315 | 1.1573 | 0.4911 | 1.4933 |
| UMP | 0.8720 | 0.7788 | 1.1623 | 1.1756 | 1.0529 | 1.0733 | 0.9311 | 0.5372 | 0.8503 | 1.1465 | 0.8243 | 1.7510 |
| Uracil | 1.3377 | 1.0088 | 0.6898 | 0.8577 | 1.1215 | 0.7929 | 1.1060 | 1.2945 | 0.9645 | 0.7600 | 1.1793 | 0.8146 |
| Urate | 1.0788 | 0.9488 | 0.9634 | 0.8595 | 1.3073 | 1.3642 | 0.7201 | 0.8800 | 0.8624 | 0.8126 | 1.1878 | 0.9495 |
| UTP | 0.8817 | 0.7684 | 2.0646 | 0.8818 | 1.3299 | 0.4631 | 1.2005 | 0.4451 | 1.0051 | 0.4884 | 0.2876 | 2.2890 |
Factors:
| F1 | Condition:IV iron | Radiation Dose:Gy10 |
| F2 | Condition:IV iron | Radiation Dose:Gy11 |
| F3 | Condition:IV iron | Radiation Dose:Gy7 |
| F4 | Condition:IV iron | Radiation Dose:Gy8 |
| F5 | Condition:IV iron | Radiation Dose:Gy9 |
| F6 | Condition:IV iron | Radiation Dose:no irradiated |
| F7 | Condition:Saline | Radiation Dose:Gy10 |
| F8 | Condition:Saline | Radiation Dose:Gy11 |
| F9 | Condition:Saline | Radiation Dose:Gy7 |
| F10 | Condition:Saline | Radiation Dose:Gy8 |
| F11 | Condition:Saline | Radiation Dose:Gy9 |
| F12 | Condition:Saline | Radiation Dose:no irradiated |