Data for (Study ST002041)
(Analysis AN003321)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this studyMetabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|
5-Hydroxyisourate | 0.9469 | 0.9236 | 0.7075 | 0.6739 | 1.0579 | 0.6745 | 1.4116 | 1.2215 | 1.1467 | 1.0675 | 1.4298 | 0.7100 |
(5-L-Glutamyl)-L-glutamine | 1.6047 | 0.8805 | 1.0568 | 1.1882 | 0.6473 | 0.4109 | 0.8232 | 1.5986 | 1.3707 | 0.8307 | 1.1819 | 0.3510 |
5-Methylthioadenosine | 0.8891 | 0.9225 | 0.8864 | 0.8858 | 0.8589 | 1.7050 | 0.8550 | 0.8050 | 1.0333 | 0.8396 | 0.8775 | 1.5606 |
5-Oxoproline | 1.0203 | 0.8629 | 0.8907 | 0.7304 | 0.9977 | 0.9347 | 1.1459 | 1.1154 | 1.1663 | 0.9768 | 1.2036 | 0.9857 |
Acetylcarnitine | 0.7445 | 0.9539 | 0.9594 | 1.3241 | 0.8301 | 0.9727 | 0.9634 | 0.9382 | 1.0626 | 1.0425 | 0.9471 | 1.3424 |
Acetylcholine | 0.9497 | 0.7008 | 0.7557 | 0.8793 | 0.5966 | 1.0143 | 1.0409 | 0.9802 | 1.2866 | 1.0709 | 1.0268 | 1.9442 |
Adenine | 0.5719 | 0.4468 | 1.3483 | 1.7087 | 1.0930 | 1.1130 | 0.8560 | 0.6317 | 1.2130 | 0.8313 | 1.0657 | 1.2040 |
Adenosine | 0.4209 | 0.3180 | 1.6271 | 2.0520 | 1.3556 | 0.9237 | 0.8336 | 0.6029 | 1.0368 | 0.8388 | 0.9216 | 1.0956 |
Allantoate | 1.3044 | 0.9896 | 0.6980 | 0.5720 | 1.3045 | 0.5500 | 1.3631 | 1.1943 | 0.9420 | 0.8822 | 1.5830 | 0.5067 |
AMP | 0.4737 | 0.2562 | 0.9191 | 1.0606 | 0.6545 | 1.3355 | 1.0733 | 0.8244 | 1.6324 | 1.1643 | 1.4402 | 1.3656 |
Anthranilate | 0.9744 | 0.7399 | 0.9059 | 0.5756 | 0.8034 | 1.2803 | 1.3065 | 1.0353 | 1.1450 | 0.7781 | 1.2750 | 1.2620 |
Argininosuccinate | 1.7016 | 1.6488 | 0.9422 | 0.4708 | 1.2050 | 0.5765 | 1.0243 | 1.1996 | 1.1118 | 0.7978 | 0.7628 | 0.4762 |
Asymmetric dimethyl arginine | 2.6150 | 2.1758 | 1.0238 | 0.5998 | 1.7282 | 0.9313 | 0.4825 | 0.6036 | 0.4225 | 0.3663 | 0.4372 | 0.3731 |
Butyrylcarnitine | 0.8737 | 0.7162 | 1.0097 | 1.1823 | 0.7510 | 1.3808 | 0.7923 | 0.7437 | 1.0506 | 0.8337 | 0.8503 | 2.0322 |
Carnosine | 1.1800 | 1.0004 | 0.7150 | 0.7461 | 0.8257 | 1.1476 | 1.0612 | 1.0754 | 0.9961 | 1.1096 | 1.0106 | 1.1644 |
Choline | 1.0614 | 1.0268 | 0.8545 | 0.7713 | 1.0618 | 0.7982 | 1.1671 | 1.0687 | 1.0879 | 1.0038 | 1.1571 | 0.9487 |
CMP | 2.3989 | 2.0567 | 0.9763 | 0.6345 | 0.4265 | 0.4252 | 0.7353 | 1.4823 | 0.8841 | 0.6065 | 0.8068 | 0.4297 |
CMP-N-acetylneuraminate | 0.1219 | 0.4782 | 0.2287 | 0.3582 | 0.2948 | 1.3492 | 1.5036 | 1.6441 | 2.0554 | 1.3343 | 1.3117 | 1.4873 |
Creatine | 1.4371 | 1.3680 | 1.0603 | 1.0414 | 1.1056 | 0.4660 | 0.9262 | 1.0325 | 1.0743 | 0.8967 | 1.0119 | 0.4936 |
Creatinine | 1.0613 | 1.0732 | 1.0055 | 1.0404 | 0.9419 | 0.8443 | 1.0782 | 0.9624 | 1.0296 | 0.8590 | 1.0759 | 1.0429 |
Cys-Gly | 0.6555 | 0.8064 | 0.9925 | 1.1350 | 0.7234 | 1.0179 | 1.0076 | 0.9977 | 1.3677 | 1.4107 | 0.8567 | 1.1279 |
Cystathionine | 1.8788 | 1.1891 | 1.1225 | 1.0235 | 0.5638 | 0.4279 | 0.7494 | 1.1266 | 1.1192 | 0.8470 | 1.3786 | 0.4967 |
Cytidine | 1.9688 | 1.9827 | 0.8580 | 0.8152 | 1.1632 | 1.4043 | 0.4449 | 0.7542 | 0.3832 | 0.4210 | 0.5278 | 1.1917 |
Cytosine | 1.5377 | 1.6060 | 0.9336 | 0.8273 | 1.0456 | 1.6429 | 0.4650 | 0.6881 | 0.5045 | 0.4196 | 0.5138 | 1.8962 |
Decanoylcarnitine | 0.8020 | 0.6689 | 1.0149 | 1.6907 | 1.1689 | 0.7925 | 0.8720 | 0.6071 | 1.3374 | 0.9394 | 1.0904 | 1.1041 |
Dimethylglycine | 1.2524 | 0.8298 | 0.4929 | 0.4256 | 1.3998 | 2.3726 | 0.6835 | 0.5719 | 0.6483 | 0.4336 | 0.7359 | 2.3543 |
Dodecanoylcarnitine | 0.8592 | 0.7104 | 1.0255 | 1.2434 | 1.1733 | 0.6632 | 1.1542 | 0.7377 | 1.4991 | 0.9203 | 1.2562 | 0.8215 |
Dopamine | 0.5025 | 0.6789 | 0.6108 | 0.5154 | 0.5278 | 0.8304 | 1.6143 | 1.3859 | 1.4855 | 0.9777 | 2.0602 | 0.8847 |
gamma-Glutamyl-gamma-aminobutyrate | 0.8592 | 0.7900 | 0.8804 | 1.1290 | 1.1357 | 0.6503 | 0.8842 | 0.8622 | 1.8074 | 1.2479 | 1.2103 | 0.6313 |
gamma-L-Glutamyl-D-alanine | 1.2495 | 0.7859 | 0.8769 | 0.8054 | 0.8929 | 0.4705 | 1.1900 | 1.4621 | 1.3883 | 0.8213 | 1.6468 | 0.3600 |
gamma-L-Glutamyl-L-cysteine | 1.4498 | 1.0950 | 1.2193 | 1.3689 | 0.8998 | 0.6539 | 0.7770 | 1.0101 | 1.1720 | 0.8841 | 1.0360 | 0.3356 |
Glutathione | 0.5914 | 0.7465 | 0.9946 | 1.1834 | 0.7404 | 1.0282 | 1.0687 | 1.0333 | 1.2928 | 1.3423 | 0.9156 | 1.1516 |
Glutathione disulfide | 0.2739 | 0.5268 | 0.4125 | 0.4496 | 0.3061 | 1.1784 | 1.3664 | 1.4461 | 1.8440 | 1.4698 | 1.4221 | 1.5914 |
glycine | 1.1729 | 0.9525 | 0.9803 | 0.7782 | 1.0029 | 0.8293 | 1.0554 | 1.1168 | 1.1187 | 0.9686 | 1.1388 | 0.8865 |
g-Oxalo-crotonate | 1.3252 | 2.1799 | 0.6707 | 0.7356 | 0.5097 | 1.3956 | 0.7534 | 1.1421 | 0.4899 | 0.7887 | 0.6144 | 1.3659 |
Guanidinoacetate | 1.3456 | 1.0215 | 0.5266 | 0.5970 | 0.6966 | 0.4743 | 1.1754 | 1.8726 | 1.0724 | 0.8937 | 1.5880 | 0.6886 |
Guanine | 1.3436 | 1.3348 | 0.7618 | 1.1109 | 1.1680 | 0.6919 | 0.9908 | 1.2061 | 0.8721 | 0.6191 | 1.1303 | 0.6814 |
Hexadecadienoylcarnitine | 0.6585 | 0.3080 | 0.7865 | 1.5846 | 0.9742 | 0.5909 | 1.2274 | 0.4861 | 1.8252 | 1.0124 | 1.8300 | 0.8515 |
Hexanoylcarnitine | 0.7229 | 0.7677 | 1.0687 | 1.2432 | 0.9170 | 1.1312 | 0.9692 | 0.7292 | 1.1880 | 0.8187 | 0.9774 | 1.6306 |
Hydroxydecanoyl carnitine | 0.9443 | 1.1310 | 0.8484 | 1.0578 | 0.9185 | 0.7131 | 1.3686 | 1.2348 | 1.2407 | 1.0563 | 0.9227 | 0.5148 |
Hydroxydodecanoyl carnitine | 1.1158 | 1.3789 | 1.0350 | 1.0496 | 0.9155 | 0.6621 | 1.1194 | 1.0392 | 1.2199 | 1.1150 | 0.8038 | 0.4873 |
Hydroxyhexadecanoyl carnitine | 1.2170 | 1.2879 | 0.9899 | 1.6611 | 0.9773 | 0.6217 | 0.9233 | 0.9720 | 1.0354 | 1.0226 | 0.7622 | 0.4208 |
Hydroxyisovaleroyl carnitine | 1.0590 | 0.7471 | 0.7716 | 0.8958 | 0.9946 | 0.8868 | 1.0360 | 1.1069 | 1.2664 | 1.0892 | 1.0697 | 1.1628 |
Hydroxynonanoyl carnitine | 1.2254 | 1.8397 | 1.0886 | 0.9506 | 1.3159 | 0.6382 | 0.6320 | 0.7953 | 1.1257 | 0.6722 | 1.1296 | 0.5147 |
Hydroxyoctanoyl carnitine | 0.9045 | 1.1541 | 1.1711 | 1.1458 | 0.8639 | 0.6503 | 1.0869 | 0.9777 | 1.2271 | 1.1683 | 0.8670 | 0.7858 |
Hydroxypropionylcarnitine | 1.1902 | 1.1334 | 0.9903 | 1.0166 | 1.1214 | 0.7249 | 1.0808 | 1.0433 | 0.9900 | 0.9339 | 1.0127 | 0.7007 |
Hydroxytetradecanoyl carnitine | 1.2988 | 1.2007 | 1.0255 | 1.2352 | 1.0286 | 0.5996 | 1.1398 | 1.0766 | 1.0710 | 0.9453 | 0.8484 | 0.4307 |
Hypotaurine | 1.3060 | 1.0206 | 0.9255 | 1.0016 | 1.0055 | 0.6457 | 0.8796 | 1.0747 | 1.2959 | 0.8896 | 1.2430 | 0.7142 |
Hypoxanthine | 1.3470 | 1.8441 | 0.7167 | 0.8580 | 0.5883 | 1.3204 | 0.8058 | 1.2119 | 0.4928 | 0.8887 | 0.5347 | 1.3624 |
Indole | 1.2283 | 1.0490 | 0.6153 | 0.5297 | 1.2115 | 0.4524 | 1.5386 | 1.2757 | 1.1650 | 0.7859 | 1.5797 | 0.5023 |
Indole-3-acetate | 1.4816 | 1.3169 | 1.1927 | 1.2596 | 1.2215 | 0.5995 | 0.9541 | 0.9275 | 0.9159 | 0.6647 | 0.9183 | 0.4136 |
Indolepyruvate | 1.6546 | 1.3856 | 0.6897 | 0.6263 | 1.3884 | 0.4869 | 1.2168 | 1.0151 | 0.9169 | 0.6456 | 1.3700 | 0.4843 |
Inosine | 1.6333 | 1.8645 | 0.8368 | 1.2079 | 1.0583 | 0.5886 | 0.9045 | 1.2204 | 0.3604 | 0.9220 | 0.5452 | 0.6627 |
Isovalerylcarnitine | 1.7136 | 1.0141 | 0.6411 | 0.6548 | 0.9204 | 0.4231 | 1.1447 | 1.2231 | 1.0997 | 0.6456 | 1.7119 | 0.7849 |
Kynurenic acid | 0.7166 | 0.9891 | 1.0015 | 0.8138 | 0.8505 | 1.1850 | 1.3663 | 1.0351 | 1.0172 | 0.9587 | 0.9804 | 1.1115 |
Kynurenine | 1.3281 | 1.2156 | 0.7796 | 0.6423 | 1.1482 | 0.3899 | 1.4847 | 1.4239 | 0.9597 | 0.7930 | 1.3338 | 0.3662 |
L-alanine | 1.1350 | 0.9160 | 0.8894 | 0.6508 | 1.0118 | 0.7584 | 1.2306 | 1.2548 | 1.1475 | 0.9277 | 1.2770 | 0.7879 |
L-arginine | 1.5332 | 1.6083 | 0.7972 | 0.5776 | 1.2678 | 0.5230 | 1.1639 | 1.3440 | 0.8802 | 0.7977 | 0.8819 | 0.5017 |
L-asparagine | 1.5245 | 1.5512 | 0.8675 | 0.6536 | 1.2042 | 0.6112 | 1.0421 | 1.1771 | 0.8514 | 0.9122 | 0.9379 | 0.5468 |
L-aspartate | 0.9254 | 0.8584 | 1.0599 | 0.8727 | 0.9289 | 1.5694 | 0.7469 | 0.7873 | 1.0002 | 0.8835 | 0.6859 | 1.8520 |
L-Carnitine | 1.0664 | 0.8469 | 0.9065 | 0.8357 | 0.8872 | 1.4249 | 0.8215 | 0.9493 | 1.0098 | 0.8942 | 0.7809 | 1.7231 |
L-Citrulline | 1.5148 | 0.6733 | 0.9305 | 1.2002 | 0.7681 | 0.9993 | 0.9538 | 1.0000 | 0.8900 | 0.9605 | 1.0277 | 1.0748 |
L-cysteine | 1.3709 | 1.8220 | 1.2501 | 1.3937 | 1.2779 | 0.4148 | 0.7870 | 1.0404 | 0.7729 | 0.7548 | 0.6355 | 0.2932 |
L-cystine | 3.1565 | 1.3365 | 1.2688 | 1.0219 | 1.8023 | 0.3999 | 0.5326 | 0.4534 | 0.5635 | 0.2768 | 0.7696 | 0.1637 |
L-glutamate | 1.1171 | 1.0245 | 1.0913 | 0.8862 | 1.0038 | 1.3973 | 0.7010 | 0.8517 | 0.8886 | 0.7924 | 0.7479 | 1.5949 |
L-glutamine | 0.9160 | 0.8243 | 0.8184 | 0.7010 | 1.0114 | 0.7290 | 1.3357 | 1.2272 | 1.2768 | 1.0687 | 1.3523 | 0.7431 |
L-histidine | 0.9014 | 0.7452 | 0.5151 | 0.4693 | 0.7861 | 0.4116 | 1.7240 | 1.5811 | 1.4403 | 1.0926 | 1.7631 | 0.5727 |
L-isoleucine | 1.2474 | 1.1065 | 0.6172 | 0.5182 | 1.1179 | 0.5137 | 1.4772 | 1.3631 | 1.0904 | 0.8482 | 1.4701 | 0.5602 |
L-leucine | 1.1476 | 1.1624 | 0.6283 | 0.5682 | 1.1276 | 0.5827 | 1.3371 | 1.3423 | 1.1267 | 0.8521 | 1.4285 | 0.6523 |
L-lysine | 1.1408 | 1.0170 | 0.5503 | 0.4385 | 1.0100 | 0.5534 | 1.5679 | 1.5062 | 1.1291 | 0.8988 | 1.5441 | 0.5872 |
L-methionine | 1.3220 | 1.4645 | 0.7654 | 0.6056 | 1.2296 | 0.6755 | 1.1372 | 1.2024 | 0.9154 | 0.7691 | 1.1412 | 0.6940 |
L-Methionine S-oxide | 1.4401 | 1.3335 | 1.5308 | 1.1320 | 1.5755 | 0.9980 | 0.7356 | 0.7273 | 0.4842 | 0.5347 | 0.6858 | 0.6490 |
L-phenylalanine | 1.2661 | 1.1319 | 0.5827 | 0.4936 | 1.0920 | 0.4942 | 1.5576 | 1.4550 | 1.0461 | 0.8153 | 1.4649 | 0.5122 |
L-proline | 1.4204 | 1.1101 | 0.7774 | 0.5292 | 1.4150 | 0.7335 | 1.0966 | 1.1090 | 1.0635 | 0.6949 | 1.2967 | 0.7082 |
L-serine | 1.3483 | 1.3332 | 0.8513 | 0.6242 | 1.2308 | 0.5778 | 1.1833 | 1.2420 | 0.9491 | 0.9330 | 1.1123 | 0.5056 |
L-threonine | 1.2335 | 1.1321 | 0.8048 | 0.6046 | 1.2068 | 0.6643 | 1.2309 | 1.2478 | 1.0471 | 0.8259 | 1.2171 | 0.7433 |
L-tryptophan | 1.1970 | 1.0809 | 0.6147 | 0.5427 | 1.2271 | 0.4695 | 1.4845 | 1.3111 | 1.1671 | 0.7929 | 1.5198 | 0.5326 |
L-tyrosine | 1.3580 | 1.3086 | 0.7048 | 0.7107 | 1.2714 | 0.5542 | 1.1714 | 1.1595 | 0.9744 | 0.8037 | 1.2861 | 0.6151 |
L-valine | 1.1107 | 1.0522 | 0.6385 | 0.5980 | 1.0649 | 0.5936 | 1.3484 | 1.3999 | 1.1411 | 0.8427 | 1.4664 | 0.7148 |
Methylmalonylcarnitine | 0.9866 | 0.7633 | 0.7338 | 0.7575 | 0.8698 | 0.7048 | 1.4903 | 1.3971 | 1.3213 | 0.9510 | 1.2816 | 0.7588 |
N1-Acetylspermidine | 1.1308 | 0.8165 | 0.7111 | 0.7431 | 1.9314 | 0.7564 | 1.2296 | 0.9465 | 0.6886 | 0.6999 | 1.4546 | 0.7865 |
N-acetyl-D-glucosamine | 1.6302 | 1.2851 | 0.6866 | 0.4813 | 1.4576 | 0.7384 | 1.1837 | 1.0189 | 0.6883 | 0.6162 | 1.5065 | 0.5562 |
N-Acetyl-L-ornithine | 1.5097 | 1.0491 | 0.8799 | 1.0804 | 0.8782 | 0.9727 | 0.8190 | 1.1786 | 1.0750 | 0.8857 | 0.8864 | 0.7504 |
Nicotinamide | 0.8614 | 0.9607 | 0.8988 | 0.9604 | 0.8833 | 1.0307 | 1.0673 | 1.1180 | 1.0850 | 1.0247 | 1.0464 | 1.1005 |
Nicotinic acid | 0.8329 | 0.8801 | 0.9659 | 0.9900 | 0.8803 | 0.7664 | 1.0201 | 0.9958 | 1.4102 | 1.1006 | 1.1429 | 1.1208 |
Octanoylcarnitine | 0.8246 | 0.7271 | 1.0017 | 1.6330 | 0.9867 | 1.0292 | 0.9640 | 0.7114 | 1.1428 | 0.8233 | 0.9308 | 1.3175 |
Octenoylcarnitine | 1.0134 | 0.9056 | 0.9048 | 0.9571 | 1.1134 | 0.7843 | 1.2611 | 0.7695 | 1.1884 | 0.8554 | 1.1592 | 1.1571 |
Ornithine | 1.4420 | 0.8552 | 0.5553 | 0.4144 | 1.1993 | 0.7260 | 1.3853 | 1.1452 | 1.1723 | 0.7081 | 1.6807 | 0.6884 |
Pantetheine | 1.7074 | 2.3363 | 1.0957 | 1.3577 | 0.9632 | 0.6555 | 0.6757 | 0.7866 | 0.5767 | 0.6343 | 0.6666 | 0.3244 |
Pantetheine 4--phosphate | 1.9122 | 2.3443 | 0.6427 | 0.5664 | 0.3554 | 0.4990 | 0.8822 | 1.4413 | 1.0455 | 0.7979 | 0.9805 | 0.4271 |
Pantothenol | 1.0610 | 1.3949 | 0.9463 | 1.0265 | 1.5265 | 0.7377 | 1.0025 | 0.8750 | 0.9230 | 0.8530 | 0.9065 | 0.6646 |
Phosphocreatine | 0.9496 | 0.4617 | 1.2643 | 1.8728 | 0.9302 | 0.2207 | 0.4787 | 0.6915 | 1.3122 | 1.5950 | 1.4453 | 0.8007 |
Phosphoserine | 1.2452 | 1.2308 | 0.8675 | 0.9188 | 1.1469 | 1.1746 | 0.8515 | 0.9333 | 0.7661 | 0.7732 | 0.8230 | 1.2778 |
Propanoyl-carnitine | 1.0704 | 1.1489 | 0.9488 | 0.8739 | 1.0468 | 0.6701 | 0.9723 | 1.0672 | 1.1519 | 0.9067 | 1.1940 | 0.9743 |
Putrescine | 2.1786 | 1.4889 | 0.8589 | 1.3784 | 2.0846 | 0.4401 | 0.7050 | 0.8233 | 0.3633 | 0.4206 | 0.6914 | 0.2995 |
S-Glutathionyl-L-cysteine | 1.1126 | 1.0570 | 1.0079 | 0.8030 | 0.9944 | 0.9999 | 1.0424 | 1.1561 | 1.1399 | 0.7963 | 1.1274 | 0.7388 |
Spermidine | 1.8376 | 1.4553 | 0.7803 | 0.5931 | 0.9038 | 0.7104 | 0.7804 | 1.4675 | 0.8021 | 0.5762 | 1.2811 | 0.7160 |
Sphingosine | 1.2577 | 1.3177 | 0.8672 | 0.6955 | 1.2925 | 0.7504 | 1.3045 | 1.0013 | 0.7647 | 0.8280 | 1.2073 | 0.5826 |
trans-4-Hydroxy-L-proline | 1.1250 | 0.5457 | 1.1191 | 0.7759 | 0.7312 | 0.9753 | 1.0985 | 1.1402 | 0.9744 | 0.9736 | 1.2851 | 1.3134 |
UDP | 1.0041 | 0.8905 | 1.1872 | 1.7136 | 0.7597 | 0.8169 | 0.8829 | 0.9049 | 1.1287 | 1.1117 | 0.8409 | 0.7307 |
Factors:
F1 | Treatment:IV iron | Radiation Dose:Gy10 |
F2 | Treatment:IV iron | Radiation Dose:Gy11 |
F3 | Treatment:IV iron | Radiation Dose:Gy7 |
F4 | Treatment:IV iron | Radiation Dose:Gy8 |
F5 | Treatment:IV iron | Radiation Dose:Gy9 |
F6 | Treatment:IV iron | Radiation Dose:no irradiated |
F7 | Treatment:Saline | Radiation Dose:Gy10 |
F8 | Treatment:Saline | Radiation Dose:Gy11 |
F9 | Treatment:Saline | Radiation Dose:Gy7 |
F10 | Treatment:Saline | Radiation Dose:Gy8 |
F11 | Treatment:Saline | Radiation Dose:Gy9 |
F12 | Treatment:Saline | Radiation Dose:no irradiated |