Data for (Study ST002078)
(Analysis AN003387)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| 2_3-Diphosphoglyceric acid | 1.4897 | 1.2574 | 1.0473 | NA | 1.1095 | NA | 1.0942 | NA |
| 3-phosphoglycerate | 1.1266 | 1.0604 | 0.8633 | NA | 1.0065 | NA | 0.9431 | NA |
| 3-phospho-serine | 1.1383 | 1.1605 | 1.2765 | NA | 1.3209 | NA | 1.1036 | NA |
| 4-aminobutyrate | 1.0665 | 1.1299 | 1.2502 | NA | 1.3265 | NA | 1.1864 | NA |
| 4-phosphopantetheine | 1.0211 | 0.9655 | 1.0279 | NA | 1.0859 | NA | 0.8995 | NA |
| 4-phosphopantothenate | 1.0526 | 1.0527 | 1.1512 | NA | 1.1240 | NA | 0.9526 | NA |
| 4-Pyridoxic acid | 1.2144 | 1.1454 | 1.2176 | NA | 1.1359 | NA | 1.1082 | NA |
| 5-phosphoribosyl-1-pyrophosphate | 0.6309 | 0.4576 | 1.3184 | NA | 1.6925 | NA | 0.9007 | NA |
| 6-phospho-D-gluconate | 0.6705 | 0.9393 | 1.2168 | NA | 1.2908 | NA | 0.8826 | NA |
| acetyl-aspartate | 1.0787 | 1.1022 | 1.0837 | NA | 1.1152 | NA | 1.0440 | NA |
| acetyl-CoA | 1.0165 | 1.0143 | 1.0412 | NA | 1.0538 | NA | 0.8741 | NA |
| Acetyllysine | 0.8504 | 0.9724 | 1.6462 | NA | 1.3707 | NA | 1.0758 | NA |
| ADP-D-glucose | 1.0988 | 0.9470 | 1.0333 | NA | 1.0405 | NA | 0.8803 | NA |
| a-ketoglutarate | 0.8428 | 0.9525 | 1.3194 | NA | 1.7335 | NA | 1.1248 | NA |
| alanine/sarcosine | 0.9366 | 1.3361 | 1.2285 | NA | 1.1079 | NA | 0.9944 | NA |
| arginine | 1.2124 | 1.3020 | 1.0396 | NA | 1.0849 | NA | 1.0853 | NA |
| asparagine | 1.2323 | 1.2660 | 1.2563 | NA | 1.1099 | NA | 1.1181 | NA |
| aspartate | 1.3039 | 1.4427 | 1.1232 | NA | 1.0810 | NA | 1.0400 | NA |
| aspartate (standard) | 1.0296 | 0.9879 | 0.9574 | NA | 0.9403 | NA | 0.9040 | NA |
| Asp-Leu-His (DLH) | 0.5650 | 0.6471 | 1.2536 | NA | 1.5358 | NA | 0.9985 | NA |
| Asp-Leu-Ser (DLS) | 0.8153 | 0.8012 | 1.5523 | NA | 1.6965 | NA | 1.1303 | NA |
| CDP | 1.5367 | 1.7907 | 1.0863 | NA | 0.6165 | NA | 0.9237 | NA |
| CDP-choline | 1.0779 | 0.9058 | 1.0262 | NA | 1.0812 | NA | 0.9089 | NA |
| CDP-ethanolamine | 1.2890 | 0.9362 | 0.9130 | NA | 0.9628 | NA | 0.8991 | NA |
| chlorpropamide | 1.0255 | 1.0337 | 1.0214 | NA | 1.0114 | NA | 0.9205 | NA |
| citrate/isocitrate | 0.9898 | 1.3498 | 1.2687 | NA | 1.0703 | NA | 1.0897 | NA |
| CMP | 1.6593 | 1.1592 | 0.5738 | NA | 0.7790 | NA | 0.8287 | NA |
| coenzyme A | 0.8824 | 0.9834 | 1.0277 | NA | 1.4109 | NA | 1.0269 | NA |
| CTP | 1.6160 | 1.3842 | 0.9865 | NA | 1.0003 | NA | 1.0121 | NA |
| cyclic-AMP | 0.7665 | 0.7796 | 1.2457 | NA | 1.2547 | NA | 0.9534 | NA |
| Cystine | 0.8192 | 0.7739 | 1.8659 | NA | 1.1335 | NA | 1.3190 | NA |
| cytidine | 1.4895 | 1.3887 | 0.9709 | NA | 0.9497 | NA | 1.2006 | NA |
| dAMP | 1.2928 | 1.2237 | 0.9536 | NA | 0.6366 | NA | 0.8933 | NA |
| dATP | 1.4354 | 1.1310 | 1.0696 | NA | 1.1749 | NA | 1.1880 | NA |
| dCDP | 0.8496 | 1.3833 | 1.2644 | NA | 0.6489 | NA | 0.8538 | NA |
| dCMP | 0.9583 | 1.4297 | 1.3211 | NA | 1.1961 | NA | 1.0752 | NA |
| dCTP | 0.9773 | 1.1333 | 1.2375 | NA | 1.2563 | NA | 1.0620 | NA |
| Decanoyl-CoA | 1.0540 | 1.2055 | 0.8619 | NA | 0.9984 | NA | 0.8802 | NA |
| dGDP/ADP | 1.1318 | 1.2657 | 1.2481 | NA | 0.9740 | NA | 1.0469 | NA |
| D-glucarate | 1.1275 | 1.1081 | 1.2774 | NA | 1.0546 | NA | 1.1320 | NA |
| D-gluconate | 1.2255 | 1.3784 | 1.0815 | NA | 1.0852 | NA | 1.2152 | NA |
| D-glyceraldehdye-3-phosphate | 1.2465 | 1.1007 | 1.0976 | NA | 1.4402 | NA | 1.1093 | NA |
| dGTP/ATP | 1.2122 | 1.1089 | 1.2040 | NA | 1.3162 | NA | 1.1559 | NA |
| dihydroorotate | 0.3481 | 0.4535 | 0.6554 | NA | 0.8345 | NA | 3.7016 | NA |
| DL-Pipecolic Acid | 1.3177 | 1.5853 | 1.1034 | NA | 0.9365 | NA | 1.0044 | NA |
| D-sedoheptulose-1/7-phosphate | 1.1123 | 1.3854 | 1.2418 | NA | 0.8902 | NA | 1.0368 | NA |
| dTDP | 1.4431 | 1.4293 | 1.1267 | NA | 0.7358 | NA | 0.9302 | NA |
| dTMP | 1.1233 | 1.3520 | 1.0670 | NA | 0.6653 | NA | 0.7923 | NA |
| dTTP | 1.4804 | 1.2012 | 1.1413 | NA | 1.1772 | NA | 0.9998 | NA |
| dUTP | 0.7758 | 0.7988 | 1.3273 | NA | 1.0930 | NA | 1.0050 | NA |
| FAD | 1.0103 | 0.9630 | 1.0207 | NA | 1.0532 | NA | 0.9528 | NA |
| FMN | 0.8987 | 1.0418 | 1.0880 | NA | 1.0497 | NA | 0.9217 | NA |
| folate | 1.0433 | 0.9907 | 0.9926 | NA | 1.0439 | NA | 0.9295 | NA |
| fructose-6-phosphate | 1.1886 | 1.1436 | 1.2388 | NA | 1.2819 | NA | 1.1467 | NA |
| fumarate | 0.9220 | 1.1732 | 1.3111 | NA | 1.4212 | NA | 1.0392 | NA |
| GDP | 0.9694 | 1.2425 | 1.1055 | NA | 0.7451 | NA | 0.9375 | NA |
| glucono-lactone | 1.2384 | 1.0658 | 1.1185 | NA | 1.2978 | NA | 1.0785 | NA |
| glutamate | 1.0649 | 1.1213 | 1.2835 | NA | 1.3647 | NA | 1.1639 | NA |
| glutamine | 1.1850 | 1.1927 | 1.2966 | NA | 1.1793 | NA | 1.1396 | NA |
| glutathione | 1.2268 | 1.0641 | 0.9561 | NA | 1.6137 | NA | 1.1388 | NA |
| glutathione disulfide | 1.3226 | 1.2745 | 1.2123 | NA | 1.1032 | NA | 1.0873 | NA |
| GMP | 1.0580 | 1.0029 | 0.7994 | NA | 1.1668 | NA | 0.9728 | NA |
| GTP | 1.2158 | 1.1616 | 1.1915 | NA | 1.2754 | NA | 1.1516 | NA |
| guanine | 1.0315 | 1.2406 | 1.4592 | NA | 1.0774 | NA | 1.1903 | NA |
| Hexose | 1.2671 | 1.2349 | 1.1720 | NA | 1.1684 | NA | 1.1479 | NA |
| hexose-phosphate | 1.1695 | 1.1494 | 1.3437 | NA | 1.3337 | NA | 1.0035 | NA |
| His-Val-Asp-Asp (HVDD) | 0.5473 | 0.7250 | 1.4116 | NA | 1.4244 | NA | 0.8917 | NA |
| hydroxyproline/Aminolevulinate | 1.1628 | 1.1940 | 1.2216 | NA | 1.1975 | NA | 1.1578 | NA |
| hypoxanthine | 1.2530 | 1.1958 | 1.2299 | NA | 1.2442 | NA | 1.0741 | NA |
| IDP | 1.1369 | 0.7255 | 1.1842 | NA | 1.1079 | NA | 0.8456 | NA |
| isoleucine | 1.1762 | 1.2423 | 1.2887 | NA | 1.1629 | NA | 1.0838 | NA |
| lactate | 0.9563 | 1.2600 | 1.3885 | NA | 1.0111 | NA | 1.1263 | NA |
| L-arginino-succinate | 0.9808 | 1.0473 | 1.1395 | NA | 0.9806 | NA | 0.8518 | NA |
| Leu-Asp (LD) | 0.7106 | 1.1111 | 1.4079 | NA | 1.5449 | NA | 1.1249 | NA |
| leucine | 1.1261 | 1.2085 | 1.3266 | NA | 1.2138 | NA | 1.1050 | NA |
| lysine | 1.2717 | 1.3696 | 1.1103 | NA | 0.9616 | NA | 1.1744 | NA |
| malate | 0.9595 | 1.1571 | 1.3963 | NA | 1.3516 | NA | 1.0959 | NA |
| maleic acid | 0.9641 | 1.1589 | 1.3865 | NA | 1.3156 | NA | 1.0923 | NA |
| methionine | 1.1735 | 1.2237 | 1.2645 | NA | 1.2055 | NA | 1.1296 | NA |
| Myristoyl/tetradecanoyl-CoA | 1.1293 | 0.9676 | 1.1470 | NA | 0.8324 | NA | 0.9237 | NA |
| N-acetyl-glucosamine-1/6-phosphate | 0.9253 | 0.8924 | 1.1633 | NA | 1.2217 | NA | 1.1293 | NA |
| N-acetyl-glutamate | 1.1766 | 1.2785 | 1.1878 | NA | 1.1777 | NA | 1.1201 | NA |
| N-acetyl-glutamine | 1.1022 | 1.2137 | 1.2311 | NA | 1.3517 | NA | 1.0505 | NA |
| N-Acetyl-L-alanine | 1.0774 | 1.3095 | 1.2305 | NA | 1.1393 | NA | 1.1323 | NA |
| N-acetyl-L-ornithine | 0.7271 | 0.7603 | 1.6758 | NA | 1.7216 | NA | 1.0978 | NA |
| NAD+ | 1.1233 | 1.0551 | 1.0641 | NA | 1.0844 | NA | 1.0063 | NA |
| NADH | 1.0049 | 1.0177 | 0.9153 | NA | 1.1211 | NA | 0.9410 | NA |
| NADP+ | 1.1054 | 0.9521 | 0.9843 | NA | 1.0417 | NA | 0.9165 | NA |
| NADPH | 1.0181 | 0.9676 | 0.8871 | NA | 1.1605 | NA | 0.9667 | NA |
| N-carbamoyl-L-aspartate | 0.4524 | 0.6415 | 1.0334 | NA | 1.0662 | NA | 2.8055 | NA |
| nicotinate | 1.1448 | 1.3378 | 1.3206 | NA | 0.9884 | NA | 1.0378 | NA |
| Octulose 8/1P | 1.2554 | 1.1122 | 1.1472 | NA | 1.1065 | NA | 1.0445 | NA |
| Octulose Bisphosphate | 1.0852 | 1.0612 | 0.9921 | NA | 0.9509 | NA | 0.9106 | NA |
| ornithine | 0.9608 | 0.9663 | 1.2793 | NA | 1.2924 | NA | 1.0838 | NA |
| Phenol Red | 0.9740 | 0.9489 | 1.0803 | NA | 1.0624 | NA | 0.9344 | NA |
| phenylalanine | 1.1178 | 1.1803 | 1.2922 | NA | 1.2401 | NA | 1.1544 | NA |
| phosphoenolpyruvate | 1.3844 | 1.2516 | 1.0181 | NA | 1.2164 | NA | 1.1221 | NA |
| Pro-Asp (PD) | 0.7741 | 0.8310 | 1.2971 | NA | 1.3909 | NA | 1.0402 | NA |
| Pro-Glu-Glu-Lys (PEEK) | 0.5871 | 0.6615 | 1.3089 | NA | 1.5542 | NA | 0.8883 | NA |
| Pro-Glu-Glu (PEE) | 0.5461 | 0.6648 | 1.3848 | NA | 1.4548 | NA | 0.9495 | NA |
| Pro-Glu (PE) | 0.8039 | 0.8550 | 1.5741 | NA | 1.6092 | NA | 1.1570 | NA |
| proline | 1.2719 | 1.1111 | 1.1207 | NA | 1.0791 | NA | 1.1564 | NA |
| Pro-Val-Asn-Phe (PVNF) | 0.6231 | 0.7123 | 1.3414 | NA | 1.4042 | NA | 0.9190 | NA |
| Pyroglutamic acid | 1.0104 | 1.0993 | 1.1640 | NA | 1.2108 | NA | 1.1233 | NA |
| Pyrophosphate | 0.9302 | 1.0457 | 1.5086 | NA | 1.2809 | NA | 1.1442 | NA |
| ribose | 1.1026 | 1.2803 | 1.2658 | NA | 1.1559 | NA | 1.0965 | NA |
| Ribose-5-phosphate | 1.0481 | 1.0992 | 1.0746 | NA | 1.1277 | NA | 0.9837 | NA |
| ribose-phosphate | 1.1055 | 1.2010 | 1.2625 | NA | 1.2864 | NA | 1.1429 | NA |
| ribulose-5-phosphate | 1.0603 | 1.1075 | 1.1924 | NA | 1.0043 | NA | 0.9685 | NA |
| S-adenosyl-L-homocysteine | 0.9692 | 1.0516 | 1.1509 | NA | 1.1340 | NA | 1.0276 | NA |
| Sedoheptulose bisphosphate | 1.0764 | 0.9602 | 0.9831 | NA | 1.0459 | NA | 0.9345 | NA |
| Ser-Asp (SD) | 0.7615 | 0.7132 | 1.3971 | NA | 1.7189 | NA | 1.0749 | NA |
| serine | 1.1158 | 1.1448 | 1.1681 | NA | 1.1064 | NA | 1.0541 | NA |
| sn-glycerol-3-phosphate | 1.2287 | 1.1824 | 1.1594 | NA | 1.2696 | NA | 1.1288 | NA |
| succinate/Methylmalonic acid | 1.0697 | 1.1129 | 1.1731 | NA | 1.1992 | NA | 1.1110 | NA |
| succinyl-CoA/methylmalonyl-CoA | 0.9391 | 0.8820 | 1.1060 | NA | 1.1720 | NA | 0.9009 | NA |
| thiamine | 1.3602 | 1.2366 | 1.0908 | NA | 1.0120 | NA | 0.9651 | NA |
| Thiamine pyrophosphate | 0.8945 | 0.9742 | 1.1232 | NA | 1.0801 | NA | 0.9281 | NA |
| threonine/homoserine | 1.1246 | 1.1688 | 1.2259 | NA | 1.2396 | NA | 1.0968 | NA |
| thymine | 0.9744 | 1.0947 | 0.9353 | NA | 1.1560 | NA | 1.2745 | NA |
| tryptophan | 1.1701 | 1.1886 | 1.2725 | NA | 1.2202 | NA | 1.1330 | NA |
| tyrosine | 1.2113 | 1.2114 | 1.2831 | NA | 1.2129 | NA | 1.0643 | NA |
| UDP | 1.2849 | 1.5401 | 1.1961 | NA | 0.7276 | NA | 0.9178 | NA |
| UDP-D-glucose | 1.0903 | 1.0043 | 0.9938 | NA | 0.9951 | NA | 0.9165 | NA |
| UDP-D-glucuronate | 1.1204 | 0.9920 | 0.9589 | NA | 1.0275 | NA | 0.9012 | NA |
| UDP-N-acetyl-glucosamine | 1.1731 | 1.0606 | 0.9375 | NA | 0.9356 | NA | 0.8932 | NA |
| UMP | 1.3617 | 1.0762 | 0.7513 | NA | 1.0017 | NA | 0.8091 | NA |
| UTP | 1.3767 | 1.2048 | 1.1829 | NA | 1.2366 | NA | 0.9984 | NA |
| Val-Asp-Pro-Val-Asn-Phe (VDPVNF) | 0.6325 | 0.6237 | 1.4958 | NA | 1.6053 | NA | 0.9745 | NA |
| Val-Asp (VD) | 0.7605 | 0.8575 | 1.5506 | NA | 1.6325 | NA | 1.1932 | NA |
| valine | 1.1064 | 1.2465 | 1.3597 | NA | 1.2095 | NA | 1.0341 | NA |
| xanthosine | 0.9136 | 0.8834 | 0.9582 | NA | 1.2197 | NA | 1.0251 | NA |
| xanthosine-5-phosphate | 0.7359 | 0.9657 | 1.3968 | NA | 1.0321 | NA | 0.8695 | NA |
| Xanthurenic acid | 0.9151 | 1.7684 | 1.3716 | NA | 0.7172 | NA | 1.1952 | NA |
Factors:
| F1 | Drug:Halofuginone |
| F2 | Drug:MMV1081413 |
| F3 | Drug:MMV1091186 |
| F4 | Drug:MMV1578884 |
| F5 | Drug:ND |
| F6 | Drug:OSM-S-106 |
| F7 | Drug:Pool |
| F8 | Drug:TCMDC-124553 |
