Data for (Study ST002099)

(Analysis AN003430)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6
2,4-Diaminobutyric acid 0.4437 2.9712 0.4059 1.1979 0.5490 0.4323
2-Aminoimidazole 0.7155 1.4561 0.8878 1.0002 1.0446 0.8959
2-Deoxyadenosine 0.4403 2.0521 0.6571 0.7448 1.1971 0.9086
2^-Deoxycytidine 5^-monophosphate 0.5220 0.9200 0.7017 0.3820 1.5184 1.9559
2-Deoxyguanosine 0.7120 1.3857 0.8234 1.3805 0.8463 0.8521
2^-Deoxyguanosine 5^-monophosphate 0.2976 0.5698 0.6277 0.1809 1.5087 2.8153
2^-Deoxyuridine 0.7610 1.6274 0.6473 1.3985 0.8777 0.6881
3-Guanidinopropionic acid? 0.5610 2.2855 0.7303 0.8925 0.9717 0.5591
5-aminosalicylic acid 0.7425 1.4027 0.6851 0.9123 1.2238 1.0335
5-Methylcytidine 0.9905 1.6950 0.7916 1.2834 0.7762 0.4633
6-Aminocaproic acid 0.9433 1.2754 0.9084 1.5033 0.8029 0.5667
Acetylcarnitine 1.2495 1.2854 0.6897 2.0105 0.5251 0.2398
Acetylcholine 0.6361 1.0412 0.8096 0.8121 1.5334 1.1676
Adenosine 0.4548 1.9370 0.8134 0.8343 1.1593 0.8011
Alanine 0.8734 1.5981 0.6998 1.3084 0.9765 0.5439
Aminoadipic acid 1.1242 0.9860 1.0456 0.7563 1.2473 0.8406
Betaine 0.7049 2.0024 0.6978 1.1534 0.8922 0.5494
Beta-Sitosterol 0.9266 1.5427 0.5661 1.0841 1.1346 0.7460
Biotin 1.0644 1.4374 0.6962 0.5506 1.1536 1.0978
Choline 1.0186 1.4146 0.8351 1.2911 0.9250 0.5156
Creatine 0.8966 1.3961 0.8583 1.9320 0.5917 0.3254
Cytidine 0.6518 1.6852 0.6051 1.2092 1.0425 0.8061
Cytidine monophosphate 0.5609 1.2793 0.8298 0.6052 1.2231 1.5018
Cytosine 0.6064 1.2045 0.5350 1.1301 1.0640 1.4601
Deoxycytidine 0.5382 1.9084 0.5289 1.6484 0.7241 0.6521
Dopamine 0.7743 1.4451 0.6449 0.7961 1.4146 0.9249
Guanidineacetic acid 0.7224 1.9704 0.6207 1.5499 0.6667 0.4699
Guanosine 5^-monophosphate 0.4886 1.1210 0.7621 0.3503 1.0739 2.2041
his 0.8416 1.4288 0.8371 1.2775 0.9993 0.6157
Histamine 0.6520 1.5768 0.5363 1.3628 0.9568 0.9152
Hypoxanthine 0.8688 1.5725 1.1602 0.8327 0.8368 0.7290
Indole-3-acetic acid 0.9291 1.8925 0.8746 0.8648 0.9583 0.4807
Inosine 0.9923 1.5886 1.1791 1.0621 0.7402 0.4376
Isoleucine 0.8643 1.8365 0.6950 1.3324 0.7479 0.5238
Isonicotinic acid 0.8181 1.5313 1.0405 0.7925 1.1062 0.7114
L-Arginine 0.7515 2.1481 0.4912 1.8773 0.4850 0.2468
L-Carnitine hydrochloride 1.1433 1.4624 0.7805 1.1619 0.8900 0.5619
L-Citrulline 0.8327 1.2991 0.7640 0.8584 1.3077 0.9380
L-Glutamate 0.7490 1.4891 0.7615 0.7758 1.2351 0.9895
L-Glutamine 0.8208 1.7048 0.6426 1.4012 0.8606 0.5699
L-Homoserine 0.8185 1.6019 0.6597 1.3611 0.9769 0.5819
L-Leucine 0.6632 1.9084 0.7205 1.3879 0.7764 0.5436
L-Lysine 0.7466 1.7618 0.5718 1.4232 0.9011 0.5955
L-Methionine 0.8680 1.7779 0.6525 1.4251 0.7989 0.4775
L-Norleucine 0.9046 1.7869 0.7298 1.2189 0.7999 0.5600
L-Ornithine 0.8397 1.8180 0.6830 1.3920 0.7507 0.5166
L-Phenylalanine 0.8334 1.8578 0.7495 1.2857 0.7431 0.5305
L-Proline 0.8986 1.3848 0.7587 1.3522 0.9714 0.6344
L-Threonine 0.8661 1.5701 0.6620 1.3156 0.9925 0.5938
L-Valine 0.7181 1.9793 0.5879 1.5712 0.6739 0.4696
N-Acetylglutamine 0.6555 2.2124 0.6851 1.0715 0.8047 0.5707
N-Acetyl-L-methionine 0.7567 1.7087 0.7033 1.3292 0.9214 0.5806
N-Acetylornithine 0.6776 1.7034 0.6869 0.9993 1.0941 0.8387
Nicotinic acid 0.8053 1.5675 1.0450 0.8094 1.0777 0.6952
Normetanephrine 1.1025 1.2893 0.8713 0.7593 1.1023 0.8753
Norvaline 0.7225 1.9900 0.5823 1.5734 0.6696 0.4621
p-Hydroxyphenylpyruvate 2.1522 0.2736 0.2682 0.1740 1.8560 1.2761
Pyridoxal 0.8269 1.6586 0.8357 0.9783 0.9478 0.7528
Pyrogallol 0.8546 1.2721 0.6233 1.2775 1.0215 0.9510
Sarcosine 0.8799 1.5749 0.7048 1.3029 0.9916 0.5459
Spermidine 0.6746 1.4022 0.8775 1.0179 0.9925 1.0354
Sphinganine 0.7714 1.4153 0.8921 0.5894 1.0908 1.2410
Syringic acid 0.1626 2.4779 0.2580 2.7905 0.1411 0.1699
Thymine 0.6253 1.1419 0.5944 0.7643 1.4742 1.4000
Trans-4-Hydroxy-L-proline 0.8633 1.8406 0.6942 1.3307 0.7475 0.5237
Tryptophan 0.8458 1.8961 0.5666 1.7071 0.6272 0.3572
Uracil 0.7642 1.3031 0.8472 0.9120 1.2531 0.9204
Uridine 5^-monophosphate 0.3545 1.2187 0.7575 0.5227 1.5884 1.5582
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Factors:

F1Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection (10 mL/kg of olive oil)
F2Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection with 10% CCl4 (10 mL/kg of olive oil)
F3Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection with 1% CCl4 (10 mL/kg of olive oil)
F4Treatment:3 times per week with 4 consecutive respectively intraperitoneal injection with 5% CCl4 (10 mL/kg of olive oil)
F5Treatment:Only intraperitoneally (i.p) injected with 1% CCl4 (10 mL/kg, dissolved in olive oil) at the 12th injection. During the previous 11 times they were treated the same as the healthy controls with an equal volume of olive oil.
F6Treatment:Only intraperitoneally (i.p) injected with 5% CCl4 (10 mL/kg, dissolved in olive oil) at the 12th injection. During the previous 11 times they were treated the same as the healthy controls with an equal volume of olive oil.
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