Data for (Study ST002104)
(Analysis AN003440)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 |
|---|---|---|---|---|---|---|---|
| 10-hydroxy-undecanoic acid | 3.8187 | 1.2263 | 0.0174 | 1.4596 | 0.3149 | 0.1383 | 0.8142 |
| 12-epi-hapalindole F (isothiocyanate) | 0.3738 | NA | 2.3512 | 2.8953 | 0.6497 | 0.7407 | 0.4051 |
| 1-carboxymethylpyridinium | 0.0932 | NA | 2.0642 | 2.1404 | NA | 0.1974 | 0.1036 |
| 1-Nitrohexane | 1.9953 | 1.8777 | 0.8972 | 0.9787 | 0.5485 | 0.5527 | 1.0295 |
| 1-Pyrroline-5-carboxylic acid | 3.4627 | 1.0535 | 0.1458 | 0.1250 | 0.2698 | 0.4203 | 0.4183 |
| 1-thio--D-glucose | 0.5982 | 0.4382 | 0.4815 | NA | 2.6115 | 0.5895 | 0.9355 |
| 2-C-Methyl-D-erythritol 4-phosphate | 1.0940 | 0.7331 | 2.0337 | 3.3676 | 0.0519 | 0.3459 | 0.5077 |
| 2-Dodecylbenzenesulfonic acid | 0.5811 | 0.7268 | 1.0425 | 2.7120 | 1.0898 | 0.7600 | 0.6726 |
| 2-Hydroxy-2,4-pentadienoate | 1.4918 | 1.3167 | 1.5029 | 1.7520 | 0.1219 | 0.4680 | 0.7650 |
| 2-Hydroxy-3-(4-hydroxyphenyl)propenoic acid | 1.8771 | 1.7943 | NA | NA | 0.2043 | 0.1752 | 0.9490 |
| 2-Hydroxy-4-(methylthio)butanoic acid | 1.0706 | 1.0137 | NA | NA | 0.4598 | 0.2167 | 1.5370 |
| 2-Hydroxycaproic acid | 1.2300 | 1.5651 | 0.3480 | 0.5510 | 1.3693 | 0.8265 | 1.0394 |
| 2-Hydroxyglutaric acid | 3.0412 | 1.3447 | 0.7878 | 0.7451 | 0.1744 | 0.1732 | 0.5071 |
| 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate | 1.9922 | 2.0082 | NA | NA | 0.1142 | 0.0570 | 0.8284 |
| 2-Methyl-4-amino-5-hydroxymethylpyrimidine diphosphate | 0.7767 | 1.0748 | 0.1618 | NA | 1.5610 | 0.6451 | 1.2218 |
| 2-Methylacetophenone | 2.3215 | 0.8820 | 1.3285 | 0.6497 | 0.5878 | 0.5355 | 0.5111 |
| (2R,4S)-2,4-Diaminopentanoate | 0.8405 | 0.6104 | 1.6607 | 1.8894 | 0.8764 | 0.9909 | 0.6484 |
| 2-trans,6-trans-Farnesal | 0.7099 | 1.1251 | 1.2099 | 0.6383 | 1.6339 | 1.5517 | 1.0298 |
| 3,3^-Thiobispropanoic acid | 2.0593 | 1.2419 | 0.8620 | 0.8225 | 0.5121 | 0.5757 | 0.8213 |
| 3^^-Chloro-3^^-deoxytriphasiol | 2.4189 | 0.5939 | 1.9644 | 2.3728 | 0.0825 | 0.0866 | 0.2599 |
| 3-Dehydroquinate | 2.0390 | 0.7151 | 0.9690 | 1.0805 | 0.5996 | 0.6755 | 0.9378 |
| 3-Ethylmalate | 1.5788 | 1.1988 | 1.1986 | 1.3048 | 0.3757 | 0.6471 | 0.8640 |
| 4-({2-[(3-{2-[2-(acetyloxy)propan-2-yl]-7-oxo-2H,3H,7H-furo[3,2-g]chromen-6-yl}-1-hydroxy-3-methylbutan-2-yl)sulfanyl]-1-[(carboxymethyl)-C-hydroxycarbonimidoyl]ethyl}-C-hydroxycarbonimidoyl)-2-aminobutanoic acid | 1.8455 | 0.1545 | NA | NA | NA | NA | NA |
| 4-Hydroxybutyric acid | 1.8501 | 2.0645 | 0.6292 | 0.6102 | 0.4457 | 0.4737 | 0.9653 |
| 4-Hydroxymethylphenylhydrazine | 1.0571 | 0.9046 | 1.5270 | 1.3052 | 0.7593 | 0.9743 | 0.7498 |
| 4-Hydroxy tolbutamide | NA | NA | NA | NA | NA | NA | NA |
| 4^-methoxycyclopenine | NA | NA | 0.7781 | 1.3258 | 0.9328 | 0.9979 | NA |
| 4-methylmorpholine N-oxide | 2.7728 | 2.1456 | 0.6102 | 0.6117 | 0.1769 | 0.2195 | 1.1327 |
| 5-Dehydro-4-deoxy-D-glucarate | 1.6202 | 0.8869 | 2.1841 | 2.5097 | 0.4976 | 0.6122 | 0.5763 |
| 5-Hydroxypentanoic acid | 1.3186 | 1.1528 | 0.8007 | 0.9417 | 0.8883 | 0.8499 | 1.9244 |
| 5-Pyridoxolactone | 1.6679 | 1.3327 | 0.9334 | 1.0026 | 0.6844 | 0.6891 | 0.7303 |
| 5-Sulfoxymethylfurfural | 2.0846 | 1.6971 | NA | NA | 0.2484 | 0.2913 | 0.6787 |
| ADP-Mannose | 0.9338 | 0.9531 | NA | NA | 1.1615 | 1.1077 | 0.8439 |
| Ala/Cys/His/Asn/Gln | 1.6453 | 1.0592 | 0.6434 | 0.7124 | 0.7752 | 0.9520 | 0.9978 |
| Ala/Ile/Ile/Val/Val | 0.3977 | 0.6335 | 0.8525 | 0.8685 | 0.9060 | 0.8316 | 0.5633 |
| Ala/Leu/Arg/Arg | 0.4016 | 0.5773 | 0.8149 | 0.8390 | 0.9212 | 0.8693 | 0.5350 |
| Ala/Met/Thr/Asp | NA | NA | 0.0363 | NA | NA | NA | 1.6425 |
| Allantoin | 0.6010 | 0.6559 | 1.8320 | 3.2948 | 0.5722 | 0.6476 | 0.4388 |
| alpha-Irone | 0.4531 | 0.4964 | 2.3795 | 3.6327 | 0.4647 | 0.6149 | 0.4546 |
| alpha-Ketoisovaleric acid | 2.4663 | 2.7327 | 0.0137 | 0.0213 | 0.4372 | 0.3151 | 1.3471 |
| a phenothiazine | 0.4973 | 3.1277 | 0.1418 | NA | 0.3734 | NA | 0.1560 |
| Arabitol | 0.5409 | 0.5260 | 1.2520 | 1.4198 | 1.2416 | 1.3764 | 0.8672 |
| Arachidonic acid | 0.2708 | 0.2241 | 2.3310 | 3.2709 | NA | NA | 0.1038 |
| Argenonic acid | 3.0912 | 0.8363 | NA | 1.4697 | 0.1683 | 0.1926 | 0.3985 |
| ascr#24 | 1.0527 | 0.9725 | 1.7218 | 1.2872 | 0.7891 | 0.8157 | 0.6974 |
| Asp/Arg/Arg/Thr/Tyr | 0.2824 | 0.3630 | 1.3293 | 3.5317 | NA | 0.2161 | 0.2444 |
| aureothricin | 0.2353 | 0.2913 | NA | NA | 2.2115 | 1.0101 | 0.7792 |
| Brassicanal B | 0.4681 | 0.5865 | 0.8356 | 0.9245 | 0.8004 | 0.7972 | 0.5656 |
| Capric acid | 1.8097 | 1.7237 | 0.7748 | 0.8479 | 0.6919 | 0.6576 | 0.9150 |
| Caprylic acid | 1.3056 | 1.5658 | 1.3659 | 0.7088 | 0.8115 | 0.9357 | 0.7842 |
| Carmustine | 1.7484 | 0.9542 | NA | NA | NA | 0.5664 | 0.4420 |
| casuarine | 1.0843 | 1.3140 | NA | NA | NA | NA | 0.6016 |
| cis-Acetylacrylate | 0.9794 | 0.9000 | 1.2607 | 1.8609 | 0.7651 | 1.1042 | 0.7618 |
| Citric acid | 1.3669 | 1.8230 | 0.7339 | 2.1739 | 0.2934 | 0.3030 | 1.5107 |
| Cyclovariegatin | NA | NA | NA | 3.2306 | 0.3606 | 0.7365 | 0.4159 |
| Cys/Lys/Lys/Gln/Arg | NA | NA | 3.0191 | NA | 1.0710 | 0.4388 | 0.1914 |
| Cys/Met/Met/Met/Trp | 0.7340 | 0.7205 | 1.0569 | 1.4818 | NA | NA | NA |
| Deoxyuridine | NA | NA | 1.0744 | 1.3413 | NA | NA | 0.1686 |
| Dodecanoic acid | 1.5027 | 1.5319 | 1.1524 | 1.2074 | 0.6796 | 0.6152 | 0.9559 |
| Ethiin | NA | NA | 3.3790 | NA | 0.8995 | 0.3255 | 0.1221 |
| FA (18:2) | 0.9811 | 1.0701 | 1.4129 | 2.4057 | 0.7948 | 0.4857 | 1.2544 |
| FA methyl(14:0) | 1.0412 | 1.0066 | 1.7897 | 2.3695 | 0.8292 | 0.7646 | 0.6750 |
| FA methyl(8:0) | 1.3823 | 1.0522 | 1.1429 | 1.0290 | 0.9316 | 0.8943 | 0.5185 |
| FA oxo(16:0) | 1.4521 | 1.3710 | 1.1004 | 1.5795 | 0.7323 | 0.5626 | 0.9207 |
| FMPP | NA | NA | NA | NA | 0.9596 | 1.2720 | 0.8590 |
| Fructose | 1.4160 | 1.7928 | 1.3942 | 1.4682 | 0.1084 | 0.3685 | 0.7394 |
| Galactose | 0.9624 | 1.2585 | 1.1363 | 1.7346 | 0.6224 | 0.9746 | 0.6015 |
| gamma-Glutamylvaline | 2.8628 | 0.8470 | 0.2271 | 0.3279 | 0.2432 | 0.2586 | NA |
| Gln/Leu/Lys/Tyr | NA | NA | 0.3842 | 1.3079 | NA | NA | NA |
| Glucosylsphingosine | 1.2071 | 1.2573 | NA | NA | NA | NA | 0.5356 |
| Glyceric acid | 1.6247 | 0.6291 | 0.9543 | 1.1343 | 0.7808 | 0.9043 | 1.0020 |
| Glycerol 3-phosphate | 1.4897 | 0.5015 | 0.0593 | 0.0607 | 1.5550 | 1.1033 | 1.2903 |
| Glyceryl lactopalmitate | 1.6409 | 0.9085 | NA | NA | NA | NA | 0.4506 |
| Heptadecanoic acid | 1.0510 | 0.9036 | 1.7922 | 2.7486 | 0.7640 | 0.7776 | 0.7086 |
| His/Met/Phe/Gly | NA | NA | 0.8087 | 1.0957 | NA | NA | NA |
| Hydroxyphenyllactic acid | 1.6019 | 1.5302 | 0.4110 | 0.4408 | 0.8514 | 0.4220 | 1.3599 |
| hydroxypyridine N-oxide | 2.3229 | 2.4880 | 0.1328 | 0.1335 | 0.1534 | 0.1248 | 1.2872 |
| Hydroxypyruvic acid | 2.2262 | 0.6973 | 1.3626 | 1.0936 | 0.4978 | 0.5129 | 0.4269 |
| indole-3-acetyl-isoleucine | 1.8624 | 0.5537 | 1.4788 | 1.9127 | 0.1289 | 0.1289 | 0.2370 |
| Indolepyruvate | 0.9114 | 1.1967 | NA | NA | 0.3508 | NA | 1.1083 |
| Koryoginsenoside R1 | 2.0505 | 0.6140 | NA | NA | NA | 0.5213 | 0.6855 |
| Lactic acid | 1.6127 | 1.8896 | 0.1848 | 0.1768 | 1.2890 | 1.0707 | 1.2103 |
| Lys/Lys/Lys/Met/Tyr | 1.3697 | 0.2633 | 0.9258 | 1.2564 | NA | NA | NA |
| Malic acid | 2.0565 | 1.6749 | 0.1465 | 0.1517 | 0.3748 | 0.9694 | 1.0589 |
| Malonic semialdehyde | 1.6439 | 1.5104 | 0.6398 | 0.7879 | 0.6071 | 0.7486 | 1.0871 |
| Myristic acid | 1.1666 | 1.0551 | 1.8810 | 2.2025 | 0.7524 | 0.7629 | 0.7028 |
| N-(1-Deoxy-1-fructosyl)proline | 1.0000 | NA | NA | NA | NA | NA | NA |
| N3-hydroxyethylcytosine | 1.5140 | 1.2418 | 1.6953 | 1.4595 | 0.2576 | 0.2784 | 0.9384 |
| N-Acetyl-beta-alanine | 0.0753 | 0.0753 | 0.9848 | 1.2790 | 2.5015 | 1.7587 | 0.4134 |
| N-Acetyl-D-mannosaminolactone | 3.2169 | 2.1235 | 0.0616 | 0.0554 | 0.2601 | 0.1853 | 0.4696 |
| N-Desmethylzopiclone | 0.7450 | 1.2824 | 1.1489 | 1.2285 | 0.9781 | 1.0828 | 0.6602 |
| Neryl formate | 1.7545 | 1.1167 | NA | 1.3248 | 0.5492 | 0.5996 | 0.7635 |
| N-Nitrosoproline | 1.5794 | 0.4858 | NA | NA | NA | 0.1207 | 1.2279 |
| Norepinephrine sulfate | 1.3108 | 1.1834 | NA | NA | NA | NA | 0.5057 |
| N-phosphocreatinate(2-) | 0.3438 | 0.3866 | NA | NA | 2.1576 | 1.2261 | 0.8860 |
| N-Undecylbenzenesulfonic acid | 0.6142 | 0.7505 | 1.1183 | 2.9729 | 1.0776 | 0.8072 | 0.6817 |
| octadecenoic acid | 1.1997 | 1.0689 | 1.5393 | 2.2204 | 0.9863 | 0.6871 | 0.8374 |
| Oxoglutaric acid | 3.2720 | 1.2043 | 0.1033 | 0.0564 | 0.2202 | 0.5986 | 0.6327 |
| PA(30:3) | 0.5556 | 0.8884 | 1.0573 | 0.8657 | 1.4564 | 1.3692 | 0.7817 |
| Palmitic acid | 1.1368 | 1.0962 | 1.8202 | 1.7931 | 0.9374 | 0.9119 | 0.7982 |
| Palmitoleic acid | 1.3402 | 1.4021 | 1.4898 | 1.9962 | 0.7677 | 0.5024 | 0.6015 |
| PG(16:0/18:1) | 0.7511 | 0.5113 | NA | NA | 2.3134 | 0.5917 | 0.8325 |
| PG(16:0/18:2) | 0.8380 | 0.7403 | NA | NA | 1.8961 | 0.7135 | 0.8122 |
| PG(18:1/22:6) | 1.4707 | 0.6497 | NA | NA | 1.3416 | 0.7147 | 0.8233 |
| PG(22:6/22:6) | 2.3558 | 0.5679 | NA | NA | 0.4153 | 0.6064 | 0.9105 |
| PGP(a-13:0/i-22:0) | 1.5035 | 1.0620 | NA | NA | NA | NA | 0.4552 |
| Phe/Ile/Met/Arg/Val | 0.7645 | 0.7061 | 2.5077 | 3.2253 | 0.2627 | 0.3467 | 0.4313 |
| Phenol sulphate | 2.5737 | 1.1020 | 0.2032 | 0.4153 | 0.7001 | 0.6795 | 0.8657 |
| Phenyllactic acid | 0.9897 | 0.9536 | 0.3989 | 0.4518 | 1.0725 | 0.3371 | 2.4133 |
| Phosphohydroxypyruvic acid | 0.6083 | 0.9341 | 1.7487 | NA | 1.0500 | 1.2462 | 0.9118 |
| Phytuberin | 1.3524 | 1.3590 | 1.0086 | 1.0744 | 0.9948 | 0.9440 | 0.8661 |
| PI(16:0/20:2) | 0.4401 | 0.4528 | NA | NA | 2.3647 | 0.9953 | 0.7471 |
| PI(16:0/22:4) | 1.6264 | 1.3921 | 0.1908 | 0.1521 | 0.9619 | 0.4714 | 1.3833 |
| PI(18:1/20:4) | 1.4711 | 0.9253 | NA | NA | 1.0951 | 0.5393 | 0.9692 |
| Pimelic acid | 2.2785 | 1.5537 | 0.0569 | 2.1345 | 0.6481 | 0.5316 | 0.7980 |
| potassium dihydrogen phosphate | 1.9744 | 1.5424 | 0.5679 | NA | 0.7642 | 0.5599 | 0.5113 |
| PS(37:1) | NA | NA | NA | NA | 0.5395 | NA | 1.4605 |
| pyrithiamine phosphate | 1.3727 | 0.4409 | NA | NA | NA | NA | NA |
| Pyruvic acid | 2.5466 | 2.7730 | 0.0345 | 0.0264 | 0.0918 | 0.6618 | 1.1640 |
| Quercetin 3^-sulfate | 1.0341 | 0.9659 | NA | NA | NA | NA | NA |
| (R) 2,3-Dihydroxy-3-methylvalerate | 2.4309 | 1.7953 | 0.4984 | 0.4245 | 0.3372 | 0.3570 | 0.7977 |
| rCdRP | NA | NA | NA | 1.0000 | NA | NA | NA |
| Ribitol 5-phosphate | NA | NA | 1.1430 | 4.8353 | 0.1059 | 0.1943 | 0.0952 |
| Secobarbital | 0.3872 | 0.6074 | 0.9136 | 0.8186 | 0.9114 | 0.8476 | 0.5354 |
| sodium dodecyl sulfate | 0.0900 | 0.0692 | 7.4966 | 0.2442 | 0.6248 | 0.9856 | 0.3984 |
| Stearic acid | 1.1804 | 1.0994 | 1.6803 | 1.8623 | 0.9384 | 0.9408 | 0.7862 |
| Succinic acid | 2.0875 | 1.5217 | 0.8739 | 1.2919 | 0.4290 | 0.6795 | 0.7396 |
| trans-Dodec-2-enoic acid | 1.7741 | 1.8397 | NA | NA | 0.2735 | 0.2389 | 0.8738 |
| Tridecanoic acid | 1.3572 | 1.3659 | 1.2042 | 1.1090 | 0.7600 | 0.7742 | 0.7218 |
| Trifluoroacetic acid | 1.5965 | 1.5485 | 1.2998 | 0.9590 | 0.4448 | 0.7341 | 0.9295 |
| tunicamine | NA | NA | 1.4263 | 2.1792 | 0.2049 | 0.4598 | NA |
| tyrosinal | 2.4844 | 2.1838 | 0.4664 | 0.4952 | 0.1602 | 0.1985 | 0.9958 |
| Tyrosine | 2.1758 | 1.3034 | 0.5981 | 0.7019 | 0.3584 | 0.3484 | 1.2806 |
| UDP-2-acetamido-3-acetamidino-2,3-dideoxy--D-mannuronate | 1.7134 | 1.2124 | NA | NA | NA | NA | 0.0741 |
| Undecanoic acid | 1.7998 | 1.3091 | 0.5143 | 1.4847 | 0.7615 | 0.7562 | 0.8952 |
| Uridine diphosphate-N-acetylglucosamine | 0.3836 | 0.2339 | NA | NA | 1.0480 | 2.3460 | 0.7331 |
| Viscutin 1 | NA | NA | NA | NA | NA | NA | NA |
| Voglibose | NA | NA | 1.1625 | 1.3384 | NA | 0.1607 | NA |
| xi-gamma-Undecalactone | 2.0613 | 1.3526 | 0.0200 | 1.7173 | 0.7157 | 0.7144 | 0.9966 |
Factors:
| F1 | conditions:CaOV3 cell line |
| F2 | conditions:CaOV3 cell line CBPR mutation |
| F3 | conditions:culture media for CaOV3 |
| F4 | conditions:culture media for OVCAR5 |
| F5 | conditions:OVCAR5_cell line |
| F6 | conditions:OVCAR5 cell line CBPR mutation |
| F7 | conditions:pooled QC |
